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The Effectiveness of Vitamin E Soft Capsules as an Antioxidant Putri, Syakirah Yasmin; Isadiartuti, Dewi; Isnaeni, Isnaeni; Aulya Farah Fahreza; Alvina Violita Mulyanto Putri; Zulfa Diana; Nafa Nazilatul Fatihah; I Gede Rekyadji Arimbawa; Alya Fakhirah; Talitha Nabilla Wijayanata; Muhammad Pramudya Pangestu; Azzalia Firdanthi; Oudrey Addriana; Umi Aida Rohma
Berkala Ilmiah Kimia Farmasi Vol. 11 No. 1 (2024): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v11i1.51902

Abstract

Antioxidants inhibited the oxidation of other molecules and played an important role in maintaining a healthy body. Antioxidants were found in fruits, vegetables, all parts of plants, and were present in the body as enzymes or products of metabolism. Vitamin E referred to a large number of natural or synthetic compounds, with alpha-tocopherol being the most active and widely distributed form in nature. Alpha-tocopherol was the most active antioxidant form of vitamin E and served as the primary lipophilic antioxidant in plasma, membranes, and tissues. The most important function of vitamin E was its antioxidant capability, counteracting free radical attacks that could damage cells and cause various degenerative diseases. Additionally, antioxidants helped reduce the effects of photoaging on the skin, potentiated anti-aging and anti-inflammatory activity, increased the rate of wound healing, and helped maintain healthy eyes and the immune system. One form of vitamin E dosage form was a soft capsule, which had several advantages, including the ease of filling the Active Pharmaceutical Ingredient (API) in liquid form, higher production capacity, and formulation uniformity compared to gelatin tablets or hard capsules. Soft capsule preparations also had rapid API release, which could result in achieving therapeutic blood levels more quickly and achieving greater bioavailability. This study aimed to evaluate soft capsule dosage forms in enhancing the effectiveness of vitamin E as an antioxidant. The research utilized review articles sourced from national and international journals, as well as scientific journals. The results showed that vitamin E supplementation in soft capsules could increase its effectiveness as an antioxidant.Keywords:  Soft Capsule, Increase Effectiveness, α-tocopherol, Vitamin E, Antioxidant
Profil Pengetahuan dan Kepatuhan Pekerja di Jawa Timur tentang Protokol Kesehatan Selama Work From Office (WFO) Putra, Anggara Satria; Denayu Pebrianti; Nur Fahmyta Zairoh; Mochamad Iqbal Jaelani; Insania Kamilla Putrihana; Tarishah Wahyu Ramadhani; Umi Aida Rohma; Farah Shafiyya Salsabila; Nuro Khoiri Asyhari; Septia Indah Fridayanti S; Febrinar Hera Rahmaniar; Nafa Nazilatul Fatihah; Broto Anung Laksono; Samirah
Jurnal Farmasi Komunitas Vol. 10 No. 2 (2023): JURNAL FARMASI KOMUNITAS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfk.v10i2.45505

Abstract

Ekonomi dalam skala internasional, pada sektor bisnis dan industri dihadapkan pada tantangan untuk mengatasi ancaman pandemi COVID-19. Pemerintah memberikan Ministerial Statement yang dikenal sebagai Work From Office (WFO) untuk mengatasi keadaan ekonomi tersebut. Tujuan penelitian ini adalah mengetahui profil pengetahuan dan kepatuhan pekerja di Jawa Timur tentang protokol kesehatan selama WFO yang meliputi tingkat pemahaman dan kepatuhan terhadap protokol kesehatan yang diterapkan. Profil pengetahuan dan kepatuhan ini diteliti secara kuantitatif melalui survei yang menggunakan teknik purposive sampling terhadap 166 responden. Instrumen yang digunakan untuk penelitian ini adalah kuesioner online menggunakan platform google form dengan sasaran responden pekerja WFO yang berlokasi kerja di wilayah Jawa Timur. Dari 166 responden, 96,99% memiliki pengetahuan yang tinggi tentang protokol kesehatan selama WFO pada masa pandemi COVID-19, tetapi hanya 61 responden (36,7%) tersebut yang tingkat kepatuhannya tinggi. Oleh karena itu, diperlukan adanya pengawasan dan dukungan sesama pekerja untuk mengingatkan dalam rangka meningkatkan kepatuhan terhadap protokol kesehatan sebagai salah satu upaya pencegahan COVID-19 selama WFO.