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Epidemiological Characteristics and 3-year Overall Survival Outcome of Nasopharyngeal Cancer in Central Java: A Single Institution Retrospective Study Liemiyah, Rikha; Ruspita, Dian Ayu; Naftali, Zulfikar; Muyassaroh, Muyassaroh; Farokah, Farokah
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1083

Abstract

Background: Nasopharyngeal cancer (NPC) has a high incidence and mortality rate in Indonesia, indicating poor survival outcomes. We aimed to evaluate the survival rate of NPC patients and the influence of specific underlying epidemiological characteristics on the overall survival (OS) rate of NPC patients. Methods: We reviewed the medical data from Dr. Kariadi General Hospital's clinical registry system for all newly diagnosed NPC patients between January and December 2018. We retrieved NPC patients' medical record data that met our inclusion/exclusion criteria. The overall survival rate (OS) was estimated using the Kaplan-Meier method. Between-group stratified three-year OS comparisons were conducted using weighted log-rank tests. All statistical analysis was performed in R statistical software. Results: A total of 50  NPC patients were included in the study. Majority of NPC patients were diagnosed in younger age group (58.0%). Male NPC patients dominated this study (74.0%). NPC patients were mostly diagnosed at the advanced stage (76.0%). Nonkeratinizing histology types were frequently found in the study (82.0%). NPC patients achieved a desirable better performance status (78.0%) and had no comorbidities (74.0%). Most NPC patients demonstrated a complete response to therapy (58.0%). The mean follow-up was 26.36 ± 9.5 months and drop-out rate was 18.0%. The three-year OS was 60.8%. Age, sex, stage, histological classification, performance status, comorbidity, therapy response, and therapy drop-out stratified OS did not statistically differ among NPC patients. Conclusions: We found a satisfactory NPC three-year OS. The underlying epidemiological characteristics did not significantly influence the NPC patients' three-year OS.
Fibrous Dysplasia in the Maxillary Bone: The Early Diagnosis of Progressive Pain with Facial Asymmetry Liemiyah, Rikha; Dewi, Anna Mailasari Kusuma; Antono, Dwi; Nugroho, Nur Iman; Muyassaroh, Muyassaroh; Kusumaningrum, Lely; Arsita, Cynthia
Indonesian Journal of Cancer Vol 19, No 1 (2025): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i1.1316

Abstract

Introduction: Fibrous dysplasia (FD) is a genetic, non-familial skeletal disorder, where in medullary bone is replaced by fibro-osseus tissue. Ninety percent of FD instances involve the craniofacial region, which usually involves one or more bones. The ethmoid, sphenoid, frontal, maxillary, and temporal bones are the most affected, but the maxilla is most affected. Misdiagnosis and inappropriate diversity in investigations and therapies are frequently caused by the disease’s rarity and varying presentation to other specialties. This study aims to analyze the signs, symptoms, and laboratory-radiology examinations of suspected FD patients at Dr. Kariadi General Hospital Semarang so that it can increase the sensitivity of medical personnel in establishing this diagnosis based on the symptoms and signs complained of by the patient.Case Presentation: A case series study assessing three patients diagnosed with FD of the maxillae between January and December 2021 at Dr. Kariadi General Hospital, Semarang. The study found 3 patients diagnosed with FD of the maxillae consisting of 2 males and 1 female. The initial complaints reported in all patients were progressive facial pain, thick sensation in the cheek area, and asymmetrical facial shape due to abnormal protrusions. Physical examination found an increase in facial volume with a hard consistency. CT scan evaluation obtained a sclerotic image with ground glass opacity in two patients and hyperostosis in one patient. Surgery with the Weber Ferguson technique was undergone by two patients, while one patient underwent the Weber Ferguson Technique + Zoledronic Acid for 6 cycles. Both patients who underwent Weber Ferguson technique surgery experienced recurrence related to symptoms in the form of pain and increased volume in the facial area within 2–4 weeks after surgery.Conclusions: Patients with complaints of progressive pain and asymmetrical shape in the facial area and physical examination found an increase in facial volume with hard consistency should be able to increase the suspicion of medical personnel regarding the diagnosis of FD. Further radiological examination with tissue histopathology should be performed to rule out or confirm the diagnosis of FD.
Implementasi program pembinaan kebugaran jamaah haji berbasis latihan terstruktur di Kota Semarang Mukarromah, Siti Baitul; Sahri, Sahri; Anggita, Gustiana Mega; Liemiyah, Rikha
Darmabakti: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 1 (2025): November
Publisher : CV Rezki Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56003/darmabakti.v2i1.667

Abstract

Mayoritas jamaah haji di Kota Semarang berusia di atas 50 tahun dan memiliki tingkat kebugaran yang beragam, dengan aktivitas fisik yang belum terstruktur sebelum keberangkatan. Kondisi ini meningkatkan risiko kelelahan, keluhan muskuloskeletal, serta menurunkan kesiapan fisik dalam menjalankan rangkaian ibadah haji. Untuk menjawab kebutuhan tersebut, tim pengabdian melaksanakan program pembinaan kebugaran berbasis latihan terstruktur yang disesuaikan dengan kondisi jamaah. Program dilaksanakan selama delapan minggu dengan pendampingan tiga sesi latihan per minggu, mencakup latihan aerobik intensitas ringan–sedang, penguatan otot, fleksibilitas, serta edukasi gaya hidup sehat terkait nutrisi, istirahat, dan manajemen stres. Metode dan hasil kegiatan, pengabdian dilaksanakan di Kota Semarang dengan melibatkan 75 jamaah yang terdaftar pada musim haji 2025. Pelaksanaan program menggunakan metode latihan terencana selama delapan minggu dengan frekuensi tiga kali setiap minggu, mencakup latihan aerobik intensitas ringan sampai sedang, penguatan otot untuk meningkatkan daya tahan, latihan fleksibilitas, serta edukasi gaya hidup sehat mengenai pola makan, istirahat, dan pengelolaan stres. Evaluasi dilakukan melalui tes kebugaran kardiorespirasi (6-minute walk test), pengukuran kekuatan otot tungkai, dan indeks massa tubuh. Hasil program menunjukkan adanya peningkatan yang bermakna pada aspek kebugaran peserta, ditandai peningkatan jarak tempuh 6MWT dari 420,3 ± 52,1-meter menjadi 510,7 ± 47,6 meter (p < 0,05), peningkatan kekuatan otot tungkai sebesar 18,4%, serta penurunan IMT rata-rata sebesar 0,9 kg/m². Peserta juga melaporkan motivasi dan pemahaman yang lebih baik terkait pentingnya persiapan fisik. Program ini terbukti efektif dan dapat direkomendasikan sebagai strategi pembinaan kebugaran bagi jamaah haji.