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All Journal Jurnal Kesehatan Masyarakat Journal of Health Education Indonesian Journal of Medicine Medica Hospitalia Diponegoro International Medical Journal (DIMJ) Indonesian Journal of Cancer
Farokah, Farokah
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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 1 
Determinant of Voice Handicap Index Degree as Dysphonia Patients’ Quality of Life Indicator Yusuf, Muhammad; Dewi, Anna Mailasari Kusuma; Yunika, Kanthi; Yusmawan, Willy; Farokah, Farokah; Budiarti, Rery; Muyassaroh, Muyassaroh
JHE (Journal of Health Education) Vol 6 No 1 (2021): April 2021
Publisher : Universitas Negeri Semarang cooperate with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jhe.v6i1.42118

Abstract

Background: Dysphonia will interfere with communication which will have an impact on social life such as depression, disrupt activities, work and can affect the quality of life. Dysphonia risk factors such as age, sex, duration of illness and etiology will affect the course of it. The purpose of this study was to identify risk factors for with the degree of Voice Handicap Index (VHI) as an indicator of dysphonia patients.Methods: Analytical descriptive study with cross-sectional design in dysphonia patients, the sample was determined as many as 62 who met the inclusion criteria. Quality of life was assessed by the VHI questionnaire. VHI degrees are classified into mild and moderate-severe. Data analysis using chi-square test and multivariate logistic regression. Results:Thirty-two (51.6%) subjects were women. Mean age was 47.26 +12.2. The most common causes of dysphonia (85.5%) were due to organic disorders and laryngopharyngeal reflux (LPR) is the most common cause (37.1%) of all organic dysphonia disorders. Analysis of risk factors for age, gender, etiology of dysphonia and duration of illness with VHI degree were p = 0.282, p =0.76, p= 0.067, p= 0.001, respectively. Duration of illness ≥2 weeks has a 38.3x risk to severity VHI compared to <2 weeks. Conclusion: The duration of illness is a determinan related to of the degree of VHI that quality of life indicator in dysphonia patients. Key Words: Risk factors, Dysphonia, Voice Handicap Index
Determinant of Voice Handicap Index Degree as Dysphonia Patients’ Quality of Life Indicator Yusuf, Muhammad; Dewi, Anna Mailasari Kusuma; Yunika, Kanthi; Yusmawan, Willy; Farokah, Farokah; Budiarti, Rery; Muyassaroh, Muyassaroh
Journal of Health Education Vol 6 No 1 (2021): April 2021
Publisher : Universitas Negeri Semarang cooperate with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jhe.v6i1.42118

Abstract

Background: Dysphonia will interfere with communication which will have an impact on social life such as depression, disrupt activities, work and can affect the quality of life. Dysphonia risk factors such as age, sex, duration of illness and etiology will affect the course of it. The purpose of this study was to identify risk factors for with the degree of Voice Handicap Index (VHI) as an indicator of dysphonia patients.Methods: Analytical descriptive study with cross-sectional design in dysphonia patients, the sample was determined as many as 62 who met the inclusion criteria. Quality of life was assessed by the VHI questionnaire. VHI degrees are classified into mild and moderate-severe. Data analysis using chi-square test and multivariate logistic regression. Results:Thirty-two (51.6%) subjects were women. Mean age was 47.26 +12.2. The most common causes of dysphonia (85.5%) were due to organic disorders and laryngopharyngeal reflux (LPR) is the most common cause (37.1%) of all organic dysphonia disorders. Analysis of risk factors for age, gender, etiology of dysphonia and duration of illness with VHI degree were p = 0.282, p =0.76, p= 0.067, p= 0.001, respectively. Duration of illness ≥2 weeks has a 38.3x risk to severity VHI compared to <2 weeks. Conclusion: The duration of illness is a determinan related to of the degree of VHI that quality of life indicator in dysphonia patients. Key Words: Risk factors, Dysphonia, Voice Handicap Index
Identifying Risk Factors of Speech and Language Delay on Children Muyassaroh, Muyassaroh; Fahrizal, Fahrizal; Naftali, Zulfikar; Yunika, Kanthi; Farokah, Farokah; Widodo, Pujo; Ruspita, Dian Ayu
KEMAS: Jurnal Kesehatan Masyarakat Vol 17, No 3 (2022)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v17i3.27676

Abstract

Speech and language delay are usually found in various disorders such as mental retardation, hearing impairment, psychosocial, autism, receptive aphasia and cerebral palsy and speech organ disorders. Retrospective research at Dr. Kariadi Hospital found that children aged 13 months to 60 months with complaints of speech problems that were subjected to an objective audiometric examination showed that 79.1% had hearing loss. This research aims to determine the relationship of risk factors with speech and language delays in children. This research was conducted in April 2020 using the cross-sectional with suspicion of late speaking who were examined by Brain evoked response audiometry (BERA) at Dr Kariadi Hospital Semarang. Researchers assessed the delay with the Languange evaluation Scale Trivandum (LEST) questionnaire. Researchers analyzed the data with chi-square test, fisher’s exact. The sample was 80 patients with the mean age was 22.35 months. Mostly in men (67.5%). The most common risk factor was hearing impairment. Hearing impairmentwas associated with speech and language delay. Economic status and bilingual were not associated with speech and language delay in children.
Epidemiological Characteristics and 3-year Overall Survival Outcome of Nasopharyngeal Cancer in Central Java: A Single Institution Retrospective Study Liemiyah, Rikha; Ruspita, Dian Ayu; Naftali, Zulfikar; Muyassaroh, Muyassaroh; Farokah, Farokah
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1083

Abstract

Background: Nasopharyngeal cancer (NPC) has a high incidence and mortality rate in Indonesia, indicating poor survival outcomes. We aimed to evaluate the survival rate of NPC patients and the influence of specific underlying epidemiological characteristics on the overall survival (OS) rate of NPC patients. Methods: We reviewed the medical data from Dr. Kariadi General Hospital's clinical registry system for all newly diagnosed NPC patients between January and December 2018. We retrieved NPC patients' medical record data that met our inclusion/exclusion criteria. The overall survival rate (OS) was estimated using the Kaplan-Meier method. Between-group stratified three-year OS comparisons were conducted using weighted log-rank tests. All statistical analysis was performed in R statistical software. Results: A total of 50  NPC patients were included in the study. Majority of NPC patients were diagnosed in younger age group (58.0%). Male NPC patients dominated this study (74.0%). NPC patients were mostly diagnosed at the advanced stage (76.0%). Nonkeratinizing histology types were frequently found in the study (82.0%). NPC patients achieved a desirable better performance status (78.0%) and had no comorbidities (74.0%). Most NPC patients demonstrated a complete response to therapy (58.0%). The mean follow-up was 26.36 ± 9.5 months and drop-out rate was 18.0%. The three-year OS was 60.8%. Age, sex, stage, histological classification, performance status, comorbidity, therapy response, and therapy drop-out stratified OS did not statistically differ among NPC patients. Conclusions: We found a satisfactory NPC three-year OS. The underlying epidemiological characteristics did not significantly influence the NPC patients' three-year OS.
PENGARUH SUPLEMENTASI KOENZIM Q10 TERHADAP KADAR LAKTAT DEHIDROGENASE PENDERITA LIMFOMA NON-HODGKIN YANG MENJALANI KEMOTERAPI DI RSUP Dr.KARIADI SEMARANG Kusulistyo, Farryanto; Suprihati, Suprihati; Yusmawan, Willy; Antono, Dwi; Budiarti, Rery; Farokah, Farokah; Widodo, Pujo
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 2 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.886 KB) | DOI: 10.36408/mhjcm.v8i2.580

Abstract

LATAR BELAKANG : Peningkatan kadar LDH dikenal sebagai penanda tumor yang menggambarkan aktivitas tumor termasuk tumor sel germinal, sarkoma dan LNH. Koenzim Q10 bekerja sebagai kofaktor dalam Siklus Krebs yang berperan dalam mengatasi kondisi kekurangan ATP dalam sel melalui reaksi reduksi dan oksidasi. TUJUAN : Membuktikan pengaruh pemberian koenzim Q10 terhadap kadar LDH penderita LNH yang mendapat kemoterapi di RSUP Dr.Kariadi, Semarang. METODE : Penelitian intervensi dengan desain randomized pre and post test double blind control group design. Subyek yang ditentukan sebanyak 34 orang. Subjek penelitian adalah penderita LNH yang mendapat kemoterapi dengan pemberian terapi selama 21 hari. Kelompok penelitian dibagi menjadi 2, yaitu kelompok perlakuan (penderita LNH yang mendapat kemoterapi, dan koenzim Q10 100mg/hari) sebanyak 17 orang, serta kelompok kontrol (penderita LNH yang mendapat kemoterapi dan plasebo) sebagai sisanya. Analisis data dengan deskriptif dan uji hipotesis HASIL : Terdapat perbedaan signifikan sebelum dan setelah intervensi, dimana terjadi penurunan kadar LDH pada kelompok perlakuan sedangkan pada kelompok kontrul justru terjadi peningkatan kadar LDH. KESIMPULAN : Kadar LDH pada pasien LNH yang diberikan koenzim Q10, lebih baik dibandingkan tanpa pemberian koenzim Q10. Terdapat perbedaan bermakna secara statistik pada penelitian ini Kata Kunci : Limfoma Non-Hodgkin (LNH); Lactate Dehidrogenase (LDH); Koenzim Q10, prognosis
FAKTOR RISIKO OBSTRUCTIVE SLEEP APNEA PADA PASIEN DIABETES MELLITUS : FAKTOR RISIKO OBSTRUCTIVE SLEEP APNEA PADA PASIEN DIABETES MELLITUS Patria, Dimas Adi; Budiarti, Rery; Ayu Ruspita, Dian; Yunika, Kanti; Tedjo Minuljo, Tania; Farokah, Farokah
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 3 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v9i3.824

Abstract

LATAR BELAKANG : Sleep Disordered Breathing(SDB) memiliki hubungan dua arah dengan sindrom metabolik seperti Diabetes Mellitus (DM) dan hipertensi, komponen sindrom metabolik meningkatkan risiko terjadinya SDB. IMT >30 kg/m2, aktivitas fisik, lingkar leher >40 cm dan hipertensi berisiko tinggi terhadap kejadian SDB. SDB telah terbukti meningkatkan risiko dan keparahan DM, sehingga penanganan SDB dibutuhkan untuk tindakan preventif  DM. TUJUAN : Mengetahui bahwa obesitas, lingkar leher besar, hipertrofi konka inferior, deviasi septum hidung, hipertrofi tonsila palatina, makroglosia, obstruksi saluran nafas atas dan hipertensi merupakan faktor resiko yang mempengaruhi kejadian SDB pada penderita DM. METODE : Penelitian observasional analitik dengan desain cross sectional melibatkan subyek sebanyak 57 penderita DM rawat jalan di Poli Penyakit Dalam RSUP Kariadi Semarang yang memenuhi kriteria inklusi pada bulan Januari 2022 - Maret 2022. Data diperoleh dari rekam medik, kuesioner ESS, pemeriksaan fisik THT dan pemeriksaan Laryngoscopy Flexible. Analisis menggunakan uji chi-square dan uji regresi multivariat. HASIL : Rerata usia 51.87 tahun, dengan SD 9.094, termuda usia 27 tahun, tertua usia  63 tahun. Laki-laki sebanyak 28(49.1%) dan perempuan 29 (50.9%). Obesitas (p= 0,036), lingkar leher besar(p=0.017), hipertrofi konka inferior(p=0,020), makroglossia(p=0,012), hipertrofi tonsila palatina(p=0,017), hipertensi (p=0,001), dan obstruksi saluran nafas atas(p=0,020) merupakan faktor risiko SDB pada penderita DM. Analisis regresi multivariat didapatkan obesitas (p=0,043 RP=13,387.CI 95%:1,083-165,475)dan hipertropi tonsil palatina(p=0,019 RP=9,703.CI 95%=1,446-65,121) merupakan faktor risiko yang paling dominan. SIMPULAN : Obesitas, lingkar leher besar, hipertrofi konka inferior, makroglossia, hipertrofi tonsila palatina, hipertensi, dan obstruksi saluran nafas atas merupakan faktor resiko SDB pada penderita DM. Obesitas dan hipertropi tonsil palatina merupakan faktor risiko yang paling dominan KATA KUNCI: SDB, DM, faktor risiko, hipertrofi tonsil, makroglosia
RISK FACTORS FOR SMELL AND TASTE DISORDER IN MILD AND MODERATE COVID-19 IN SEMARANG Dewi, Anna Mailasari Kusuma; Astika, Ismiar; Farokah, Farokah; yunika, kanti; Marliyawati, Dwi
Diponegoro International Medical Journal Vol 4, No 2 (2023): December 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i2.17892

Abstract

ABSTRACK Background: COVID-19 can make smell and taste disorder due to Angitensin Converting Enzyme 2 (ACE2) binding to olfactory tractus and taste bud that affected by gender, age, comorbid and COVID-19 severerity.Aim: To analyze age, gender, comorbid and COVID-19 severity as risk factor for smell and or taste disorder in mild and moderate Covid -19 patient in SemarangMethods: Observational research used cross section design. Sample is COVID-19 patients age >10 years old with severity mild and moderate nonhospitalize that record on Health Center of Semarang City June – July 2021. Sampling metode using purposive sampling with secondary data. Association between variable analyze using Chi square or Fisher exact test, multivariate analyze with logistic regression.Results: Research on 4337 people, 2.0% smell disorder and 0.5% taste disorder. Prevalence COVID-19 mostly on women 50.5% and adult (20-60 years old) 82.5%. Risk factor gender, age and COVID-19 severity is not associated with smell and taste disorder on COVID-19 patients (p<0.05). Chronic liver disease as a risk factor only for smell disorder on COVID-19 patients (p 0.04, CI 3.029-786.993, RP 48.828). Conclusion: Chronic liver disease is a comorbid as a risk factor for smell disorder ini COVID-19 patients at Semarang. age, gender and other comorbid not as a risk factor for smell and or taste disorder. 
Effect of Administration of Phaleria Macrocarpa on Liver Function of Nasopharyngeal Carcinoma Patients who Receive Cisplatin Chemotherapy Akbar, Adi Januar; Yusmawan, Willy; Farokah, Farokah; Nugroho, Nur Iman
Indonesian Journal of Medicine Vol. 7 No. 1 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.248 KB)

Abstract

Background: Nasopharyngeal cancer (NPC) is a malignant tumor located in the nasopharynx, which can be treated by Cisplatin, a chemotherapy that has a side effect of increasing the production of Reactive Oxygen Species (ROS) that can damage the liver. We aim to determine the effect of giving Mahkota Dewa (Phaleria macrocarpa) as an antioxidant on liver function of NPC patients receiving Cisplatin chemotherapy. Subjects and Method: Forty subjects of stage III and IV Nasopharyngeal Carcinoma patients were divided into treatment and control groups. Subjects will be tested for SGOT SGPT before cisplatin chemotherapy. The treatment group was given Phaleria macrocarpa capsules 300 mg/24 hours for 5 weeks since a week before chemotherapy. The control group was given placebo capsules/24 hours for 5 weeks since a week before chemotherapy. The patients received two series of cisplatin chemotherapy with an interval of 3 weeks, then a second blood sample was taken 1 week after the second series of cisplatin chemotherapy.Results: There was a significant difference in SGOT levels in the post-treatment group of Phaleria macrocarpa and control, as well as the difference in the pre- and post- treatment group between the Phaleria macrocarpa and control groups. Also, there was a significant difference in SGPT levels in the pre- and post- treatment in the Phaleria macrocarpa and control groups.Conclusion: The administration of Phaleria macrocarpa has an effect on decreasing the levels of SGOT and SGPT in NPC patients receiving Cisplatin chemotherapy therapyKeywords: Phaleria macrocarpa, SGOT, SGPT, Nasopharyngeal Carcinoma, CisplatinCorrespondence: Adi Januar Akbar. ENT Department of Diponegoro University. Prof. Sudarto Street No. 13, Tembalang, Tembalang Sub-district, Semarang City, Central Java, 50275. Email: diaz17akbarsaleh­@gmail.com. +628161455179.Indonesian Journal of Medicine (2022), 07(01): 1-8https://doi.org/10.26911/theijmed.2022.07.01.01
Co-Authors Akbar, Adi Januar Aminuyati Antono, Dwi Astika, Ismiar Ayu Ruspita, Dian Budiarti, Rery Dewi, Anna Mailasari Kusuma Kanti Yunika, Kanti Kusulistyo, Farryanto Liemiyah, Rikha Marliyawati, Dwi Muhammad Yusuf Muyassaroh Muyassaroh Nugroho, Nur Iman Patria, Dimas Adi Pujo Widodo, Pujo Ruspita, Dian Ayu Suprihati - Tedjo Minuljo, Tania Willy Yusmawan, Willy Yunika, Kanthi Zulfikar Naftali, Zulfikar