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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran Diponegoro Majalah Kedokteran Bandung Jurnal Kesehatan Masyarakat Indonesian Journal of Cancer Chemoprevention Oto Rhino Laryngologica Indonesiana Medica Hospitalia Indonesian Journal of Global Health research Indonesian Journal of Cancer
Zulfikar Naftali, Zulfikar
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Pengaruh Hemodialisis Terhadap Kejadian Kurang Pendengaran Sensorineural Pada Penderita Gagal Ginjal Kronik Ulfa, Loriana; Muyassaroh, Muyassaroh; Naftali, Zulfikar; Arwanto, Arwedi; Murbani, Ita
Majalah Kedokteran Bandung Vol 48, No 2 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.479 KB) | DOI: 10.15395/mkb.v48n2.763

Abstract

Kurang pendengaran sensorineural (KPSN) dapat terjadi pada kasus gagal ginjal kronik (GGK) yang dilakukan hemodialisis (HD). KPSN akibat HD terjadi pada berbagai frekuensi. Faktor yang diduga dapat mempengaruhi adalah usia, hipertensi, diabetes melitus (DM). Menganalisis pengaruh HD terhadap kejadian KPSN pada penderita GGK. Penelitian kohort pada 52 penderita GGK yang memenuhi kriteria inklusi. Terdiri dari dua kelompok, 26 penderita GGK mendapat HD dan 26 penderita GGK tanpa HD. Kelompok HD dilakukan pemeriksaan timpanoaudiometri sebelum HD dan setelah HD III. Kelompok tanpa HD dilakukan pemeriksaan timpanoaudiometri dalam waktu yang sama. Data usia, hipertensi, DM diperoleh dari rekam medik. Analisis menggunakan uji Chi-Square. Didapatkan 30,7% penderita KPSN dari kelompok HD, terdiri dari 26,9% derajat ringan dan 3,8% derajat sedang. Rerata penurunan NAP adalah 8,13 ± 5,30. Tidak didapatkan KPSN pada kelompok tanpa HD. Hemodialisis berpengaruh terhadap kejadian KPSN (p=0,004). Usia (p=0,084), hipertensi (p=0,215), DM (p=0,683) tidak berpengaruh terhadap kejadian KPSN. Hemodialisis berpengaruh terhadap kejadian KPSN. Usia, hipertensi dan DM tidak berpengaruh terhadap kejadian KPSN. [MKB. 2016;48(2):98–104]Kata kunci: Gagal ginjal kronik, hemodialisis, kurang pendengaran sensorineuralThe Effect of Hemodialysis on Sensorineural Hearing Loss in  Chronic Renal Failure PatientsSensorineural hearing loss (SNHL) can occur in patients with chronic renal failure (CRF) who receive hemodialysis (HD). SNHL is caused by hemodialysis occured in any frequency. The factors affect the disease include, among others, age, hypertension, and diabetes mellitus (DM).  The effect of hemodialysis onSNHL occurrence in patients with CRF was analyzed in this study. It was a cohort study on 52 patients with CRF who met the inclusion criteria. The sample consists of two groups, 26 patients with CRF who received hemodialysis and 26 patients with CRF who did not received hemodialysis. Timpanoaudiometry was performed on HD group (patient with HD) before the first HD and after the third HD. Timpanoaudiometry was performed on HD group (patient without HD) at the same time with  the first group. The data on age, hypertension, and DM were obtained from medical records. The results were analyzed with Chi-Square test. It was found that 30.7% SNHL patients  were in the HD group consisting of 26.9% mild degree patients and 3.8% moderate degree patients . Mean of hearing threshold decrease was 8.13 ± 5.30. There was no patient with SNHL in the non-HD group. Analysis with Chi-Square test showed that hemodialysis affects SNHL occurrence (p=0.004). Age (p=0.084), hypertension (p=0.215), and DM (p=0.683) do not affect SNHL occurrence. It is concluded that hemodialysis affects SNHL occurrence whileage, hypertension, and DM do not. [MKB. 2016;48(2):98–104]Key words: Chronic renal failure, hemodialysis, sensorineural hearing loss
THE DIFFERENCE OF NEUTROPHIL LYMPHOCYTE RATIO (NLR) IN CONVENTIONAL AND ELECTRIC SMOKERS Sarah, Diah Ayu Siti; Naftali, Zulfikar; Yusmawan, Willy; Suprihati, Suprihati
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (402.527 KB)

Abstract

Background: Smoking is an unhealthy lifestyle causing health problems that may lead to high morbidity and mortality rates. One way to stop smoking habit is by replacing conventional cigarettes with electric cigarettes. Cigarette smoke exposure can trigger an inflammatory reaction that can be measured using Neutrophil Lymphocyte Ratio (NLR). Aim: Proving of NLR in electric smoker are higher than conventional smoker. Method: The research used descriptive analytic design. The number of samples were 34 people, divided into 17 people each group (conventional smoker and electric smoker). The subjects were asked to fill out a questionnaire and their blood samples were taken by 3 cc. Then, the blood samples were tested in a laboratory to obtain NLR values. The data was then analyzed using unpaired T-test.  Result: NLR mean in the conventional smoker group is 1,364 ± 0,28 and 1,791 ± 0,49 in the electric smoker group. The unpaired T-test indicates there is significant difference in the value of NLR between conventional smoker and electric smoker (p=0,005).  Conclusion: NLR in electric smoker are higher than conventional smoke.
Identifying Risk Factors of Speech and Language Delay on Children Muyassaroh, Muyassaroh; Fahrizal, Fahrizal; Naftali, Zulfikar; Yunika, Kanthi; Farokah, Farokah; Widodo, Pujo; Ruspita, Dian Ayu
KEMAS: Jurnal Kesehatan Masyarakat Vol 17, No 3 (2022)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v17i3.27676

Abstract

Speech and language delay are usually found in various disorders such as mental retardation, hearing impairment, psychosocial, autism, receptive aphasia and cerebral palsy and speech organ disorders. Retrospective research at Dr. Kariadi Hospital found that children aged 13 months to 60 months with complaints of speech problems that were subjected to an objective audiometric examination showed that 79.1% had hearing loss. This research aims to determine the relationship of risk factors with speech and language delays in children. This research was conducted in April 2020 using the cross-sectional with suspicion of late speaking who were examined by Brain evoked response audiometry (BERA) at Dr Kariadi Hospital Semarang. Researchers assessed the delay with the Languange evaluation Scale Trivandum (LEST) questionnaire. Researchers analyzed the data with chi-square test, fisher’s exact. The sample was 80 patients with the mean age was 22.35 months. Mostly in men (67.5%). The most common risk factor was hearing impairment. Hearing impairmentwas associated with speech and language delay. Economic status and bilingual were not associated with speech and language delay in children.
Factors Associated with Hearing Loss in Helicopter Aircrew of Indonesian Army Aviation Center, Semarang Muyassaroh, Muyassaroh; Sayuti, Fajri Imam; Ruspita, Dian Ayu; Dewi, Anna Mailasari kusuma; Budiarti, Rery; Naftali, Zulfikar; Widodo, Pujo
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 12, No 2 (2021): December 2021
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.258 KB) | DOI: 10.30659/sainsmed.v12i2.12819

Abstract

Introduction: Hearing loss and tinnitus may occur in pilots due to exposure of the high noise level (ranges from 104-110 dB) generated by aircraft/helicopters. In addition, flying time, acoustic trauma, diabetes mellitus, hypertension and smoking are risk factors of hearing loss. Objective: to identify the factors associated with hearing loss in the crew of the Indonesian Army Aviation Center, SemarangMethods: in the cross-sectional research, 114 military helicopter aircrews aged 20-58 years, working for the Army Aviation Center in Semarang were included. The exclusion criteria were history of previous ear surgery, infection of the outer and middle ear, the use of ototoxic drugs (kanamycin, cisplatin and carboplatin). The level of hearing loss and tinitus was assessed by otoscopy and audiometry. Whereas, tinnitus was obtained from the history taking. Data were analyzed using chi-square test and fisher's exact and Yates’s correction.Results: One hundred and fourteen subjects (mean age of 26.54 + 4.72) were included. Several factors such as flight time (p = 0.698), acoustic trauma (p = 0.151), diabetes mellitus (p = 0.596), smoking (p = 0.222), hypertension (p = 0.356) were not associated with sensorineural hearing loss. Several factors such as flight time (p = 0.706), acoustic trauma (p = 0.5160), diabetes mellitus (p = 0.789), smoking (p = 0.495), hypertension (p = 0.112) were not associated with tinnitus.Conclusion: There is no association between flight time, acoustic trauma, diabetes mellitus, hypertension, and smoking and hearing loss.
Epidemiological Characteristics and 3-year Overall Survival Outcome of Nasopharyngeal Cancer in Central Java: A Single Institution Retrospective Study Liemiyah, Rikha; Ruspita, Dian Ayu; Naftali, Zulfikar; Muyassaroh, Muyassaroh; Farokah, Farokah
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1083

Abstract

Background: Nasopharyngeal cancer (NPC) has a high incidence and mortality rate in Indonesia, indicating poor survival outcomes. We aimed to evaluate the survival rate of NPC patients and the influence of specific underlying epidemiological characteristics on the overall survival (OS) rate of NPC patients. Methods: We reviewed the medical data from Dr. Kariadi General Hospital's clinical registry system for all newly diagnosed NPC patients between January and December 2018. We retrieved NPC patients' medical record data that met our inclusion/exclusion criteria. The overall survival rate (OS) was estimated using the Kaplan-Meier method. Between-group stratified three-year OS comparisons were conducted using weighted log-rank tests. All statistical analysis was performed in R statistical software. Results: A total of 50  NPC patients were included in the study. Majority of NPC patients were diagnosed in younger age group (58.0%). Male NPC patients dominated this study (74.0%). NPC patients were mostly diagnosed at the advanced stage (76.0%). Nonkeratinizing histology types were frequently found in the study (82.0%). NPC patients achieved a desirable better performance status (78.0%) and had no comorbidities (74.0%). Most NPC patients demonstrated a complete response to therapy (58.0%). The mean follow-up was 26.36 ± 9.5 months and drop-out rate was 18.0%. The three-year OS was 60.8%. Age, sex, stage, histological classification, performance status, comorbidity, therapy response, and therapy drop-out stratified OS did not statistically differ among NPC patients. Conclusions: We found a satisfactory NPC three-year OS. The underlying epidemiological characteristics did not significantly influence the NPC patients' three-year OS.
Hubungan Kebisingan Dengan Gangguan Pendengaran Dan Kejiwaan Para Pekerja Terpapar Bising Subekti, Rohmatullah; Muyassaroh, Muyassaroh; Naftali, Zulfikar
Medica Hospitalia : Journal of Clinical Medicine Vol. 6 No. 2 (2019): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.313 KB) | DOI: 10.36408/mhjcm.v6i2.391

Abstract

Latar belakang: Kebisingan di tempat kerja seringkali menjadi problem bagi tenaga kerja. Paparan bising dapat menyebabkan gangguan auditori yaitu noise-induced hearing loss (NIHL) dan gangguan non auditori berupa gangguan kejiwaan seperti depresi, kecemasan serta stress. Tujuan: Untuk mengetahui hubungan antara kebisingan terhadap kejadian gangguan pendengaran dan kejiwaan pada pekerja terpapar bising. Metode: Penelitian ini bersifat deskriptif analitik dengan design belah lintang. Tingkat kebisingan diukur dengan menggunakan alat sound level meter (SLM), gangguan pendengaran dinilai dari hasil audiometri, gangguan kejiwaan dinilai dari jawaban kuesioner Depression Anxiety Stress Scale 42 (DASS 42) dari WHO. Analisis data dengan uji chi square. Hasil : Data yang didapatkan dari 326 sampel menunjukkan bahwa 179 (54.9%) subjek mempunyai masa kerja lebih dari 10 tahun dan 147 (45.1%) subjek mempunyai masa kerja kurang dari 10 tahun. Sebanyak 51 (15.6%) pekerja mengalami NIHL dan 154 (47.2%) pekerja mengalami gangguan jiwa. Terdapat hubungan antara lama paparan bising (P= 0.000) dan intensitas kebisingan (P= 0.022) terhadap kejadian NIHL, dan intensitas kebisingan terhadap derajat keparahan depresi (P= 0.007) Kesimpulan: Lama paparan dan intensitas bising berhubungan dengan gangguan pendengaran sedangkan intensitas bising berhubungan dengan derajat keparahan depresi. Dibandingkan dengan intensitas bising, lama paparan bising mempunyai hubungan yang lebih besar terhadap kejadian NIHL. Kata kunci : Kebisingan, NIHL, depresi, ansietas, stres Background: Noise can raise significant issues in the workplaces. It can affect either auditory disturbance called Noise Induce Hearing Loss (NIHL) or non-auditory disturbance involving psychiatric disorders such as depression, anxiety and stress. Objective: To examine the relationship between noise in the workplace and the incidence of hearing impairment and psychiatric disorders. Method: The study design is analitic desciptive with cross-sectional approach. The noise level was measured with sound-level-metre (SLM), hearing disorders was assessed with audiometric and psychiatric disorder was assessed with Depression Anxiety Stress Scale 42 (DASS 42). The data were analized with chi square. Results : A total of 326 workers were sampled during this study showing that 179 (54.9%) workers have worked over 10 years and 179 (54.9%) workers have worked less than 10 years. It was found that 51 (15.6%) workers suffered from NHIL and 154 (47.2%) workers suffered from mental disorders. A significant relationship was found between the incidence of NIHL and years of noise exposure (P= 0.000) and noise intensity (P= 0.022). A significant relationship was found between noise intensity and depression severity (P= 0.007) Conclusion: The years of noise exposure and noise intensity were related to haring disorders. The noise intensity were related to the depression severity. In comparison with noise intensity, a stronger relationship was found between years of noise exposure and the incidence of NIHL. Keywords : Noise, NIHL, depression, anxiety, stress
Faktor Risiko Air Bone Gap Pada Otitis Media Supuratif Kronik Inardi, Yoke Kurniawan; Widodo, Pujo; Naftali, Zulfikar; Yusmawan, Willy
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.224 KB) | DOI: 10.36408/mhjcm.v7i1.422

Abstract

Latar belakang : Kehilangan pendengaran merupakan komplikasi otitis media kronik (OMSK) yang paling sering, jenis kehilangan pendengaran yang tersering adalah tuli konduktif, yang disebabkan oleh adanya air bone gap (ABG), ABG pada pasien OMSK mempunyai variasi yang berbeda-beda dan karakter yang khas berdasarkan faktor risiko. Tujuan : Menganalisis hubungan faktor risiko dengan ABG pada penderita OMSK. Metode : Penelitian desain observational analitik retrospektif di RSUP Dr Kariadi Semarang pada bulan September 2018 - Januari 2019. Data diambil dari rekam medis. jumlah sampel ditentukan sebanyak 100. Analisis data dengan uji chi-square. Hasil : Jenis kelamin laki-laki 46 orang, wanita 54 orang, rerata usia 32 tahun. Status osikula, lama sakit, kolesteatom, luas perforasi membran telinga berhubungan terhadap ABG (p <0,05). Kesimpulan : Faktor risiko (status osikula, lama sakit, kolesteatom, perforasi membran timpani) berhubungan dengan air bone gap pada penderita OMSK. Kata kunci : Air bone gap, faktor risiko, otitis media supuratif kronik. Background: Hearing loss is the most frequent complication of chronic otitis media (CSOM), hearing loss is usually caused by conductive deafness caused by the presence of an air bone gap (ABG). ABG in CSOM patients has different variations and distinctive characters based on the factors. Objective: To analyze the relationship of risk factors ABG in CSOM patients. Methods: Observational analytic study with a retrospective observational analytic design at Dr. Kariadi Hospital Semarang in September 2018 - January 2019. Subjects were 100 patients. Data retrieval is done based on medical records about history taking, physical examination and investigation. Data were analyzed by Chi-square test. Results: A total male 46 and female. Avarage age 32 years. Oscular status, duration of illness, cholesteatom, area of ??ear membrane perforation associated with ABG (p <0.05). Conclusion: Risk factors (osicular status, duration of illness, cholesteatom, tympanic membrane perforation) associated with air bone gap in CSOM patients. Keywords: Chronic supurative otitis media, air bone gap, risk factors
Risk Factors for Peripheral Vertigo Sekarwangi, Yuni Retno; Marliyawati, Dwi; Yunika, Kanti; Naftali, Zulfikar
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.977

Abstract

Background: Several risk factors influence the occurrence of peripheral vertigo, including advanced age, gender, and chronic metabolic diseases. This disease is not widely recorded in primary care due to the need for detection with simple examinations. Research on the association of several risk factors has yet to be reported. Objectives: To examine the relationship between age, gender, type 2 diabetes mellitus (DM2), and hypertension as risk factors for peripheral vertigo. Methods: This study is a case-control study that used consecutive sampling. The study sample consisted of 39 people: 19 in the case group and 20 in the control group. Data were obtained from 2 health centers and Diponegoro National Hospital, Semarang City. The data were obtained from history taking and physical examinations such as the Gans Sensory Organization Performance Test (SOP), past pointing test, and dysdiadokokinesia test. DM2 disease and hypertension were gathered from medical records. Data analysis used univariate analysis, bivariate analysis with chi-square, and logistic regression multivariate analysis. Results:  Statistical test results concluded that hypertension is a risk factor for peripheral vertigo (p = 0.008; OR = 6.964; 95%CI = 1.657 - 29.263). Whereas age, gender, and DM2 were not risk factors, with p-values of 0.187, 0.378, and 0.417, respectively. Conclusion: The significant risk factor associated with the occurrence of peripheral vertigo was hypertension by 6.964 times.
The Relationship Between Cumulative Platinum-Based Chemotherapy Dose And The Occurrence Of Ototoxicity In Head And Neck Malignancies Purnomo, Hendro; Marliyawati, Dwi; Muyassaroh, Muyassaroh; Ruspita, Dian Ayu; Naftali, Zulfikar
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.1085

Abstract

BACKGROUND: Chemotherapy is a treatment for head and neck malignancies. Hearing impairment is a side effect of chemotherapy, especially caused by platinum-based chemotherapy. Hearing impairment generally occurs at high frequencies after the administration of chemotherapy. AIMS: To prove assosciation between cumulative doses of platinum-based chemotherapy and ototoxic events in head and neck malignancies. METHOD: This is a cross-sectional study. The sample is patients with head and neck malignancy receiving platinum-based chemotherapy at Dr. Kariadi Hospital Semarang from March to June 2023. Hearing assessment using pure tone audiometry was performed randomly at all chemotherapy cycles. Data was analyzed with a chi-square test. RESULT:  Eighty-one subjects (52 male, 29 female), consisting of 71 subjects received cisplatin, and 10 subjects received carboplatin. Ototoxicity occurs in 91.7% of subjects receiving cumulative doses of cisplatin >300mg/m2 and carboplatin >1500mg/m2 compared to cumulative doses of cisplatin <300mg/m2 and carboplatin <1500mg/m2, which was 46.7% (p = 0.001, CI 1.416-2.725). CONCLUSION: There was a significant association between cumulative doses of platinum-based chemotherapy and ototoxicity incidence of head and neck malignancy patients.
Relationship mastoid pneumatization and eustachian tube shape with tympanic cavity in chronic otitis media Herjanto, Ferry; Naftali, Zulfikar; Santosa, Yanuar Iman; Hendaraningrum, Farah
Oto Rhino Laryngologica Indonesiana Vol. 52 No. 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v52i2.457

Abstract

ABSTRACTBackground: Chronic suppurative otitis media (CSOM) is one of the causes of morbidity and mortality in developing countries. The worldwide prevalence of CSOM according to WHO is estimated at 330 million people. Pneumatic type mastoid pneumatization, narrow Eustachian tube angle, and narrow Eustachian tube diameter in the diseased ear can result in cholesteatoma formation. Objective: This study aimed to determine the relationship between mastoid pneumatization, Eustachian tube angle and diameter with tympanic cavity abnormalities in CSOM patients. Methods: This was a retrospective analysis study using cross sectional method. The data were taken from the patient’s medical records at Dr. Kariadi Hospital, Semarang, from January 2020 to June 2021. Subjects were CSOM sufferers. Mastoid multisliced computed tomography (MSCT) scan examination was carried out in the Radiology Section, using the AW Volume Share 5 application, to assess the type of mastoid pneumatization, Eustachian tube angle, Eustachian tube diameter, and tympanic cavity abnormalities in the form of cholesteatoma, granulation, and erosion of the ossicles. Statistical analysis using Chi Square test, and multivariate test. Result: There were 90 subjects with CSOM, 44 (48.9%) had tympanic cavity abnormalities and 46 (51.1%) without tympanic cavity abnormalities. Sclerotic mastoid pneumatization was more than pneumatic (p=0.001), narrow Eustachian tube angle (p=0.041), and narrow Eustachian tube diameter (p=<0.001). Logistic regression results showed that mastoid pneumatization had a dominant relationship to abnormalities in the tympanic cavity. Conclusion: There was a relationship between sclerotic mastoid pneumatization, narrow Eustachian tube angle, and narrow Eustachian tube diameter with abnormalities in the tympanic cavity. ABSTRAKLatar belakang: Otitis media supuratif kronik (OMSK) merupakan salah satu penyebab morbiditas serta mortalitas di negara berkembang. Prevalensi OMSK menurut WHO di seluruh dunia diperkirakan 330 juta orang. Pneumatisasi mastoid tipe pneumatik, sudut tuba Eustachius yang sempit, dan diameter tuba Eustachius yang lebih sempit pada telinga yang sakit dapat menyebabkan terjadinya kolesteatoma. Tujuan: Penelitian bertujuan untuk mengetahui hubungan pneumatisasi mastoid, sudut dan diameter tuba Eustachius dengan kelainan kavum timpani pada penderita OMSK. Metode: Merupakan penelitian analisis retrospektif menggunakan metode cross sectional. Data diambil dari rekam medis pasien di RSUP Dr.Kariadi Semarang, dari Januari 2020 sampai Juni 2021. Subjek adalah penderita OMSK. Pemeriksaan multisliced computed tomography (MSCT) scan mastoid dilakukan di Bagian Radiologi, dengan aplikasi AW Volume Share 5, untuk menilai jenis pneumatisasi mastoid, sudut tuba Eustachius, diameter tuba Eustachius, dan kelainan kavum timpani berupa kolesteatoma, granulasi, dan erosi pada osikula. Analisis statistik menggunakan uji Chi Square, dan uji multivariat. Hasil: Didapatkan 90 subjek penderita OMSK, adanya kelainan kavum timpani 44 (48,9%) dan yang tidak adanya kelainan kavum timpani 46 (51,1%). Pneumatisasi mastoid sklerotik lebih banyak daripada pneumatik (p=0,001), sudut tuba Eustachius sempit (p=0,041), dan diameter tuba Eustachius pendek (p=<0,001. Hasil regresi logistik menunjukan bahwa pneumatisasi mastoid memiliki hubungan yang dominan terhadap kelainan pada kavum timpani. Kesimpulan: Terdapat hubungan antara pneumatisasi mastoid sklerotik, sudut tuba Eustachius sempit, dan diameter tuba Eustachius kecil dengan kelainan pada kavum timpani.  
Co-Authors Aminullah, Yusuf Aminuyati Arwanto, Arwedi Budiarti, Rery Dewi, Anna Mailasari Kusuma Efendi, Dhanang Farokah, Farokah Fitria Handayani Hendaraningrum, Farah Hendro Purnomo Herjanto, Ferry Hertanto Wahyu Subagio Inardi, Yoke Kurniawan Kanti Yunika, Kanti Liemiyah, Rikha Marliyawati, Dwi Murbani, Ita Muyassaroh Muyassaroh Pujo Widodo, Pujo Ruspita, Dian Ayu Santosa, Damai Sarah, Diah Ayu Siti sayuti, fajri imam Sekarwangi, Yuni Retno Subekti, Rohmatullah Suprihati - Ulfa, Loriana Willy Yusmawan, Willy Yanuar Iman Santosa Yunika, Kanthi