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All Journal PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Pharmaceutical Sciences and Research (PSR)
Ariestanti, Donna Maretta
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Agriculture, Biological Sciences & Forestry Economics, Econometrics & Finance Law, Crime, Criminology & Criminal Justice Public Health Social Sciences

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Exploring Rosella (Hibiscus sabdariffa L.) Calyx Extracts as Natural Dye and Antioxidants in Lip Cream Product: Formulation and Evaluation Ariestanti, Donna Maretta; Mun'im, Abdul; Djajadisastra, Joshita; Hutami, Riska Amalia Putri; Fadhila, Redhalfi; James, Richard Johari
Pharmaceutical Sciences and Research Vol. 10, No. 3
Publisher : UI Scholars Hub

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Abstract

Rosella, also known as Hibiscus sabdariffa L., is a plant that contains anthocyanin compounds in its calyx, which are known for their antioxidant properties. These compounds give the plant a captivating red color and can be used as natural dyes. This study aimed to exploit anthocyanins in rosella calyx as natural dyes and antioxidants in lip cream product. The formulations employed extracts from rosella calyx, a viscous extract from maceration in 96% ethanol (F1) and a commercially available powdered rosella extract (F2). Evaluation on the formulations demonstrated that both F1 and F2 effectively maintained the color integrity of the lip cream. Moreover, an irritation test among 10 respondents showed no adverse reactions. Additionally, a hedonic test of 30 respondents revealed uniformity in homogeneity, odor, and spreadability on both formulations. However, a noticeable contrast emerged in color intensity, with F2 exhibiting greater intensity and preference over F1. The rosella calyx extract also demonstrated its antioxidant potential with an IC50 value of 130.11 ± 2.08 µg/ml. The study highlights the utility of rosella calyx extracts as a dual-functioning component in lip cosmetics. The findings indicate the variations in formulation efficacy and color intensity, emphasizing the potential of rosella-derived extracts in developing cosmetics with enhanced aesthetic appeal and functional antioxidant attributes.
Antioxidant Activities and Protective Effects of Shorea macrophylla Leaf and Bark Extracts Ramli, Salfarina; Sukri, Nik Nor Sabrina; Zulkifli, Nur Adhwa’ Faqihah; Ariestanti, Donna Maretta; Choo, Chee Yan; Halim, Hasseri; Manshoor, Nurhuda; James, Richard Johari
Pharmaceutical Sciences and Research Vol. 11, No. 1
Publisher : UI Scholars Hub

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Abstract

Shorea macrophylla, also known as the ‘Engkabang’ tree or Light Red Meranti, is renowned for its role in reforestation efforts. Despite lacking records of traditional use, the reported biological activities of other species within the Shorea genus spark curiosity about the potential biological activities of this plant. Therefore, this study aims to explore the antioxidant capabilities of S. macrophylla leaf and bark extracts, along with their protective effects against oxidative stress using a brine shrimp model. In the evaluation of antioxidant potential, 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays were employed. Extracts were incubated in DPPH and FRAP solutions, and absorbances were measured at 517 and 593 nm, respectively. The brine shrimp lethality assay (BSLT) involved exposing brine shrimps (Artemia salina) to various concentrations of the extract, with LC50 values determined through probit regression analysis. Oxidative stress protection assays entailed treating brine shrimps with safe doses of S. macrophylla extracts before exposure to H2O2, with subsequent observation of survival rates. The DPPH assay unveiled IC50 values of 1.025 and 0.693 mg/mL for S. macrophylla leaf and bark extracts, respectively, while FRAP values exhibited a concentration-dependent relationship. BSLT demonstrated concentration-dependent mortality, with LC50 values of 0.93 and 0.6455 mg/mL for S. macrophylla leaf and bark extracts, respectively. Pre-treatment with S. macrophylla extracts significantly increased brine shrimp survival against H2O2-induced oxidative stress. In conclusion, both S. macrophylla leaf and bark water extracts demonstrated noteworthy antioxidant activities and exhibited protective effects against oxidative stress in brine shrimps. These findings provide insights into the antioxidant activities and protective effects of S. macrophylla Leaf and Bark extracts.
Pemberdayaan Masyarakat Desa Sukajaya Sumedang Selatan dalam Produksi Minuman Kesehatan dan Bumbu Rempah berbasis Teknologi Farmasi: Empowering the Sukajaya Village Community South Sumedang in the Production of Health Drinks and Spices based on Pharmaceutical Technology Elya, Berna; Forestrania, Roshamur Cahya; Rahmasari, Ratika; Ariestanti, Donna Maretta; Nur, Syamsu
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 2 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i2.5888

Abstract

As a result of observations and joint discussions with the Village Community, information was obtained that there are agricultural products in the form of spices with high annual production quantities. However, the selling value of these spices still needs to be improved. Technology has not touched them and has yet to be managed optimally. Therefore, the team empowers the community to process herbs into food products, namely health drinks and spices based on pharmaceutical technology. This activity aims to improve community welfare and mutual elements of human resources in the region. This activity was attended by 28 community members who are Partners and Village Officials. Social empowerment of the society involved in the downstream activities of agricultural products in Sukajaya Village will be carried out through socialization stages, FGD with society and village officials, establishing a micro business plan for downstream health drink products and spices building production facilities, and assistance. This activity produces products in spices, health drinks, and herbal candy. At least 80-90% of the community understands each stage of the activity so that it can become a provision for self-development. The output of this activity is in the form of innovative products, such as health drinks and spice products, which can increase partner empowerment.
Co-Authors Berna Elya Choo, Chee Yan Fadhila, Redhalfi Forestrania, Roshamur Cahya Halim, Hasseri Hutami, Riska Amalia Putri James, Richard Johari Joshita Djajadisastra, Joshita Manshoor, Nurhuda Mun'im, Abdul Rahmasari, Ratika Ramli, Salfarina Sukri, Nik Nor Sabrina Syamsu Nur, Syamsu Zulkifli, Nur Adhwa’ Faqihah