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Erawati, Rika
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Agriculture, Biological Sciences & Forestry Education Health Professions Public Health Other

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Efektivitas E-Liquid Daun Bungkus (Smilax Rotundifolia) Terhadap Nyamuk Anopheles Penyebab Malaria Ni'ma, Eka Savira; Hardiansyah, La Ode; Fadhilah, Windi Nur; Erawati, Rika; Muslihin, A. M.; Fabanyo, Syahrul H; Mustopa, Mustopa; Maulana, Fajar
Biolearning Journal Vol 11 No 02 (2024): Biolearning Journal (Juli 2024)
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalbiolearning.v11i02.4880

Abstract

Malaria is a public health problem that predominantly occurs in Eastern Indonesia. Papua is a highly endemic area for Anopheles mosquitoes. According to the Sustainable Development Goal (SDG), malaria is the target disease for pandemic elimination by 2030. The highest cases are in the eastern region of Indonesia with a percentage reaching 86%. Efforts have been made to prevent the transmission of malaria by the local government, such as the distribution of insecticide-treated mosquito nets and the proliferation of various types of mosquito repellent. Currently, the government itself is preventing the spread of malaria by distributing insecticide-treated mosquito nets and using mosquito repellent, but this has detrimental impacts. Insecticide-treated bed nets can decrease in effectiveness over time. Using mosquito coils can trigger respiratory problems and cause mucosal cells to enlarge (hypertropy) and mucous glands to increase in number (hyperplasia) resulting in narrowing of the airways. So there is a need for other alternatives, one of which is wrap leaves (Smilax rotundifolia) as a vegetable insecticide. Wrap leaves (Smilax rotundifolia) contain saponin which has stomach poisoning properties for insects. This research uses a true experimental design method to see the effectiveness of e-liquid leaf wrap. This research used 150 mosquitoes obtained from areas with high malaria cases in the Sorong area. Mosquitoes were divided into 3 groups consisting of a 30 minute time group, a 60 minute time group and a 90 minute time group. By giving the same treatment to each group, namely a concentration of 20% of the active substance of wrapper leaves (Smilax rotundifolia). The results of this study show that there is an effect of a 20% concentration of e-liquid in the leaves of the wrapper (Silax rotundifolia) on Anopheles mosquitoes, which is proven by mosquitoes that are knocked off and die. 
Uji Aktivitas Antioksidan Fraksi Ekstrak Etanol Tali Kuning (Anamirta cocculus) Dengan Metode DPPH Erawati, Rika; Muslihin, A. M.; Hardia, Lukman
Jurnal Promotif Preventif Vol 7 No 2 (2024): April 2024: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/jpp.v7i2.1264

Abstract

Tumbuhan tali kuning (Anamirta cocculus) ialah tumbuhan obat yang secara turun-temurun sudah dimanfaatkan sebagai obat antimalaria. Penelitian tentang pemisahan serta penentuan zat-zat aktif di tumbuhan tersebut menunjukkan adanya kandungan senyawa alkaloid kuartener di akar serta batangnya. Tujuan penelitian ini adalah untuk menentukan aktivitas antioksidan fraksi ekstrak etil asetat, fraksi ekstrak kloroform dan fraksi ekstrak n-heksan dengan metode DPPH. Tali kuning diesktraksi dengan metode maserasi menggunakan pelarut etanol 70%. Ekstrak etanol tali kuning (Anamirta cocculus) di fraksinasi dengan tiga pelarut yaitu etil asetat, kloroform dan n-heksan. Masing-masing fraksi diuji aktivitasnya terhadap radikal bebas DPPH dan diukur absorbansinya menggunakan spektrofotometri uv-vis pada panjang gelombang 516,2 nm. Hasil penelitian menunjukkan bahwa fraksi etil asetat, fraksi kloroform dan fraksi n-heksan tali kuning (Anamirta cocculus) memiliki aktivitas antioksidan dengan nilai IC50 masing-masing 16,16 μg/mL, 42,56 μg/mL, dan 129,03 μg/mL. Berdasarkan penelitian yang dilakukan dapat disimpulkan bahwa fraksi etil asetat dan fraksi kloroform memiliki aktivitas antioksidan sangat kuat sedangkan fraksi n-heksan sedang.
Co-Authors A. M. Muslihin Fabanyo, Syahrul H Fadhilah, Windi Nur Hardiansyah, La Ode Lukman Hardia Maulana, Fajar Mustopa Mustopa Ni'ma, Eka Savira