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The Profiles of Infantile Hemangiomas Patients hidayati, Arie; earlia, Nanda; Sari, Ninda; Vella; Maulida, Mimi; asrizal, Cynthia wahyu
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 2 (2023): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.2.2023.130-135

Abstract

Background: Infantile hemangiomas (IH) are the most prevalent benign tumors in children, predominantly in girls. Most IH cases do not require treatment due to spontaneous involution, but 10% of cases do require early treatment due to size, location, and complications. Purpose: This study tried to define the profile, clinical aspects, and therapy of IH in Dr. Zainoel Abidin General Hospital, Banda Aceh. Methods: A descriptive approach using a retrospective analysis employing secondary data from the outpatient clinic's patient registration book. This study included all new cases of infantile hemangioma at the outpatient clinic general hospital between 2013 and 2021. Result: A total of 105 patients were involved in this study. The majority of IH patients (59%) were under the age of one year, with 64 female patients (61%) making the most visits to the pediatric clinic in 2017, 2018, and 2019 (77.1%). The most prevalent clinical features of skin lesions were nodules in 69 individuals (65.7%), and the most common site was the facial region (13.3%) in 44 patients. In 20 individuals, a combination of propanolol and oral corticosteroids was used as the most effective treatment strategy (19% ). Conclusion: Infantile hemangiomas is the most frequently reported benign tumor in children. Females are more likely than males to develop IH. The majority of IH is minor and normally resolves on its own without therapy. However, certain rare kinds of IH require clinician attention and systematic treatment.
Generalized Pustular Psoriasis in Childhood: A Rare Case Asnawi, Vella; Maulida, Mimi; Earlia, Nanda; Hidayati, Arie; Ismida, Fitri Dewi; Liana, Mahda Rizki; Maghfirah, Karamina; Bulqiah, Mikyal
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.231-236

Abstract

Background: Generalized pustular psoriasis (GPP) rarely occurs under 10 years of age. GPP is typically characterized by an eruption of generalized pustules accompanied by systemic symptoms such as fever for several days, malaise, and anorexia. Pustules are sterile, with a size of 2-3 mm, and spread over the trunk and extremities. This disease can be life-threatening; therefore, optimal therapy is required. Purpose: to report a rare case of GPP in childhood. Case: A 4-year-old girl with complaints of widespread red patches that spread to her neck, back, and hands, with red patches turning into streaks that are partially pus-filled and itchy. In almost all parts of the body, skin abnormalities were seen in the form of generalized erythematous plaques, well-defined borders, multiple pustules on the edges, and some plaques covered by thick scales and crusts. In the calculation of body surface area (BSA), the result is 44%, and in the calculation of generalized pustular psoriasis area and severity index (GPPASI), the result is 21.30. The patient was treated with combination topical therapy of 3% salicylic acid, desoximethasone cream 0.25%, momethasone cream 0.1% vaseline albume as emollients, and coal tar. Significant improvement was seen after 1 month of therapy. Discussion: GPP in children is a rare case. GPP is idiopathic and can be life-threatening. Until now, there has been no standard therapy that is considered the most effective and safe for children. Topical therapy may be an option.
A fatal case of Harlequin ichthyosis: Experience from low-resource setting Vella, Vella; Maulida, Mimi; Earlia, Nanda; Hidayati, Arie; Handriani, Risna; Gondokaryono, Srie P.; Dwiyana, Reiva F.; Doris , Ezigbo E.; Pradistha , Aldilla; Bulqiah, Mikyal
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.302

Abstract

Harlequin ichthyosis is a severe and fatal presentation of ichthyosis with an autosomal recessive inheritance. Infants with Harlequin ichthyosis have a high mortality rate, and a dismal prognosis; therefore the majority of neonates die shortly after birth from infection, heat loss, dehydration, electrolytic imbalances, or respiratory distress. The aim of this case report was to present a fatal case of Harlequin ichthyosis with no family history of any inherited skin disorder. A 3-day-old baby was presented to the emergency room with congenital abnormalities at birth, fissured hyperkeratotic skin, and thick yellow plates of scales. The parents had no history of consanguineous marriage, no relevant past medical history, and no family history of the same condition. The patient was unwell, pulse 162 times/minute, respiratory rate 48 times/minute, and axillary temperature 36.9oC. APGAR score was 8 in the 1st minute and 9 in the 5th minute. Based on the typical clinical appearance, the patient was diagnosed with Harlequin ichthyosis. Due to a lack of facility, a mutation analysis was not carried out. The patient was then transferred to the neonatal intensive care unit (NICU) and treated in a humidified incubator and medicated with intravenous antibiotics (ampicillin sulbactam 125 mg/12 hour and gentamicin 13 mg/24 hour), topically fusidic acid and mild emollients. A central venous catheter was used for intravenous access. The poor prognosis resulted in the patient dying at the age of 5-day-old. This case highlights that prenatal diagnosis is critical for early detection and disease prevention. Mutation screening for the ABCA12 gene is suggested for consanguinity marriages and with a history of ichthyosis.
Dermatological Presentations in Systemic Lupus Erythematosus: A Comprehensive Case Study Earlia, Nanda; Salim, Fitria; Hidayati, Arie; Pradistha, Aldilla; Ibrahim, Teuku Maulana Malik; Azzahra, Shelda Syifa; Maulidina, Rizka Yuliani
Indonesian Journal of Case Reports Vol. 2 No. 2 (2024): December 2024
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v2i2.188

Abstract

Lupus erythematosus (LE) is an inflammatory autoimmune disease with a broad clinical spectrum of multi-organ inflammation and can be life-threatening. Manifestations of LE can occur confined to the skin (cutaneous lupus erythematosus, CLE) or systemic involving several organs such as the kidneys, heart, and lungs (systemic lupus erythematosus, SLE). We report a female, 27-year-old with complaints of black spots on her back, stomach area, hands, and feet. The patient feels that the spots increase when doing activities outside the home. Patients also complain of fever, pain when swallowing, joint pain, fatigue, and hair loss. Dermatological status in the abdominal, posterior thoracic, and extremities regions shows the presence of macules accompanied by hyperpigmented patches with unclear borders, irregular edges, gutta-plaque size, multiple numbers, and atypical arrangement and configuration. In the ANA profile examination, the native SS-A antigen (60 kDa) +++ results were strongly positive. The examination results concluded CLE type Subacute CLE (SCLE). The patient was given Calcium Carbonate capsules, Folic Acid tablets, and Methylprednisolone tablets. Topical medications include tretinoin 0.25% cream, momethasone 0.1% cream, Desoximethasone 0.25% cream, clobetasol propional 0.05% cream, and must use Sunscreen morning and evening. After 2 weeks, the patient showed good results. The black spots are starting to fade. Other complaints, such as fever, fatigue, and pain when swallowing, have decreased. Cutaneous lupus can be a challenge to treat because the symptoms are varied and complex. Management of CLE aims to eliminate symptoms and signs of the disease, prevent damage from occurring, minimize side effects of drugs, and improve quality of life.
Dermagistry: Sistem Registri Penyakit Dermato Alergo-Imunologi : Dermagistry: Dermatology Allergy-Immunology Disease Registry System Earlia, Nanda; Hidayati, Arie; Bulqiah, Mikyala; Agustyananda, Dedi
Journal of Medical Science Vol 6 No 2 (2025): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v6i2.224

Abstract

Penyakit dermato alergo imunologi merupakan penyakit kulit yang ditandai dengan keterlibatan sistem imunitas. Penyakit ini merupakan penyakit kulit dan kelamin yang cukup banyak diderita oleh pasien dan mendominasi keluhan penyakit kulit pada umumnya. Saat ini, kebutuhan akan data sangat penting. Data penting digunakan untuk keperluan klinis, penemuan obat hingga untuk data epidemiologi sehingga dibutuhkan suatu sistem registri.  Disease Registry System (DRS) adalah sistem dengan standar data tentang populasi pasien yang telah ditentukan sebelumnya berdasarkan penyakit atau kondisi yang sama yang dikumpulkan, dianalisis, dan dilaporkan secara berkelanjutan. Tujuan penelitian ini adalah untuk terciptanya sistem registri penyakit dermato alergo imunologi berbasis web-aplikasi. Penelitian ini observasional analitik dengan desain kohort prospektif dengan penggunaan teknologi sistem registri (WebApp). Telah berhasil dibuat portal Web-Aplikasi Sistem Registri Dermato Alergo-Imunologi telah selesai dan dapat digunakan dengan nama “Dermagistry (https://dermagistry.id/). Melalui portal ini diharapkan data pasien dapat disimpan dengan baik dan dapat dimanfaatkan untuk data baik untuk penelitian dan pelayanan.