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All Journal Program Kreativitas Mahasiswa - Pengabdian Kepada Masyarakat Berkala Ilmu Kesehatan Kulit dan Kelamin Narra J Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh Indonesian Journal of Case Reports
Mikyal Bulqiah, Mikyal
Fakultas Kedokteran Universitas Syiah Kuala, Banda Aceh
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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ARTHERY (Action and Rehabilitation to be Healthy for Geriatry) Pratama, Rovy; Bulqiah, Mikyal
Program Kreativitas Mahasiswa - Pengabdian Kepada Masyarakat PKM-M 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ARTHERY (Action & Rehabilitation to be heatlhy for Geriatry) is a social programs that have a long-term goal to improve the quality of life of the elderly who suffer knee osteoarthritis and prevents osteoartristis progression. The program is implemented at the UPTD Rumoh Seujahtra Geunaseh Sayang that is the only nursing home in the city of Banda Aceh for three months. The method applied in this program is introduce laterally wedged insoles and do osteoarthritis exercise. The results of the implementation of this program are improvement average of WOMAC scores on pain and stiffness of knee osteoarthritis in 13 people and 55 other elderly people have undergone knee osteoarthritis prevention program with 12 times oateoartritis exercise and wearing laterally wedged insoles.Keywords: Laterally wedged insoles, Osteoarthritis Exercise, UPTD Rumoh Seujahtra Geunaseh Sayang
Generalized Pustular Psoriasis in Childhood: A Rare Case Asnawi, Vella; Maulida, Mimi; Earlia, Nanda; Hidayati, Arie; Ismida, Fitri Dewi; Liana, Mahda Rizki; Maghfirah, Karamina; Bulqiah, Mikyal
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.231-236

Abstract

Background: Generalized pustular psoriasis (GPP) rarely occurs under 10 years of age. GPP is typically characterized by an eruption of generalized pustules accompanied by systemic symptoms such as fever for several days, malaise, and anorexia. Pustules are sterile, with a size of 2-3 mm, and spread over the trunk and extremities. This disease can be life-threatening; therefore, optimal therapy is required. Purpose: to report a rare case of GPP in childhood. Case: A 4-year-old girl with complaints of widespread red patches that spread to her neck, back, and hands, with red patches turning into streaks that are partially pus-filled and itchy. In almost all parts of the body, skin abnormalities were seen in the form of generalized erythematous plaques, well-defined borders, multiple pustules on the edges, and some plaques covered by thick scales and crusts. In the calculation of body surface area (BSA), the result is 44%, and in the calculation of generalized pustular psoriasis area and severity index (GPPASI), the result is 21.30. The patient was treated with combination topical therapy of 3% salicylic acid, desoximethasone cream 0.25%, momethasone cream 0.1% vaseline albume as emollients, and coal tar. Significant improvement was seen after 1 month of therapy. Discussion: GPP in children is a rare case. GPP is idiopathic and can be life-threatening. Until now, there has been no standard therapy that is considered the most effective and safe for children. Topical therapy may be an option.
Pengaruh Fototerapi Terhadap Mikrobioma Kulit dan Keparahan Penyakit Pada Pasien Dermatitis Atopik: Effect of Phototherapy on Skin Microbiome and Disease Severity in Atopic Dermatitis Patients Earlia, Nanda; Elfa Wirdani Fitri; Bulqiah, Mikyal; Tasrif, Aqil Yuniawan
Journal of Medical Science Vol 5 No 1 (2024): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v5i1.139

Abstract

Dermatitis atopik (DA) merupakan salah satu penyakit inflamasi kronis bersifat gatal dan residif. Pasien DA cenderung mengalamiinfeksi kulit yang dapat memperparah dan mencetus kekambuhan. Modalitas tatalaksana DA sedang dan berat terkini adalah penggunaan fototerapi. Fototerapi dengan menggunakan Narrowband-UVB (NB-UVB) dapat dipertimbangkan sebagai terapi lini kedua pasien DA sedang dan berat setelah gagal terapi lini pertama. Selain efek antiinflamasi, fototerapi NB-UVB memiliki efek antibiotik sehingga bermanfaat dalam mengatasi infeksi kulit pada pasien DA. Tujuan penelitian ini adalah untuk mengetahuiefektivitas pemberian fototerapi terhadap mikrobioma kulit dan keparahan penyakit DA. Penelitian ini merupakan penelitian uji klinis(clinical trials) desain paralel dengan matching. Populasi penelitian ini adalah seluruh penderita DA yang berobat di poliklinik kulit dankelamin RSUDZA yang memenuhi kriteria inklusi dan ekslusi. Sebanyak 20 pasien terlibat dalam penelitian ini, yang terbagi menjadi 2 kelompok yaitu kelompok perlakuan yaitu pasien yang diterapi dengan fototerapi sebanyak 2 kali per minggu, selama 4 minggu dan kelompok kontrol tanpa fototerapi. Pemeriksaan keparahan penyakit dengan parameter SCORAD, EASI, ADSI, TEWL dan Scap sertaswab kulit untuk deteksi mikrobioma dilakukan sebelum dan sesudah intervensi. Hasil analisa menggunakan uji t tidak berpasanganmenunjukkan pemberian fototerapi selama 8 kali secara signifikan mengurangi keparahan penyakit dengan parameter SCORAD, EASI, ADSI, TEWL dan Scap (nilai p<0.05) dibandingkan dengan kelompok kontrol. Namun, tidak halnya dengan mikrobioma kulit(p>0.05).
Systemic manifestation of necrotic erythema nodosum leprosum: A case report of a fatal leprosy Maulida, Mimi; Vella, Vella; Budini, Sulamsih S.; Kamarlis, Reno K.; Junaidi, Fachrul; Pradistha, Aldilla; Bulqiah, Mikyal
Narra J Vol. 3 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i2.216

Abstract

Necrotic erythema nodosum leprosum (ENL) is an uncommon manifestation of type 2 lepra reaction, encountered in lepromatous and borderline lepromatous cases of leprosy. Necrotic ENL is associated with the involvement of multiple organs, therefore delayed diagnosis and treatment will lead to complications and poor prognosis. The aim of this case report was to report a challenging case of necrotic ENL misdiagnosed with multiple cellulitis since there were no signs of prior leprosy nor had any antimycobacterial treatment. A 45-year-old man was presented to the surgery department of Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia, with complaints of fever, joint pain, and painful tender skin lesions with ulceration over the trunk, extremities, and ears for one month. The patient was diagnosed clinically with multiple cellulitis and underwent a debridement procedure. Clinical improvement was absent, the patient was then consulted to the dermatology department. Physical examination showed normal vital signs, madarosis, inguinal lymphadenopathy, thickening of nerves, and sensation of numbness in both hands and feet. Laboratory examinations on admission showed leucocytosis, anemia, thrombocytopenia, hypoalbuminemia, hypocalcemia, and elevated creatinine and ureum level. A slit skin smears examination yielded positive acid-fast bacilli (AFB) with a bacteriological index (BI) value of 3+ and morphological index (MI) of 72%. The patient was diagnosed with lepromatous leprosywith necrotic ENL reaction. Intravenous methylprednisolone and cefoperazone-sulbactam were given. Multidrug therapy mulitbacillary (MDT-MB) without dapsone, and ofloxacin 400 mg was initiated. On day 17, the patient had septic shock. The patient became unconscious and experienced death. This case highlights that medical professionals should be aware of the various manifestations of necrotic ENL to correctly diagnose and provide treatment as soon as possible to prevent mortality, especially in leprosy-endemic country, Indonesia.
A fatal case of Harlequin ichthyosis: Experience from low-resource setting Vella, Vella; Maulida, Mimi; Earlia, Nanda; Hidayati, Arie; Handriani, Risna; Gondokaryono, Srie P.; Dwiyana, Reiva F.; Doris , Ezigbo E.; Pradistha , Aldilla; Bulqiah, Mikyal
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.302

Abstract

Harlequin ichthyosis is a severe and fatal presentation of ichthyosis with an autosomal recessive inheritance. Infants with Harlequin ichthyosis have a high mortality rate, and a dismal prognosis; therefore the majority of neonates die shortly after birth from infection, heat loss, dehydration, electrolytic imbalances, or respiratory distress. The aim of this case report was to present a fatal case of Harlequin ichthyosis with no family history of any inherited skin disorder. A 3-day-old baby was presented to the emergency room with congenital abnormalities at birth, fissured hyperkeratotic skin, and thick yellow plates of scales. The parents had no history of consanguineous marriage, no relevant past medical history, and no family history of the same condition. The patient was unwell, pulse 162 times/minute, respiratory rate 48 times/minute, and axillary temperature 36.9oC. APGAR score was 8 in the 1st minute and 9 in the 5th minute. Based on the typical clinical appearance, the patient was diagnosed with Harlequin ichthyosis. Due to a lack of facility, a mutation analysis was not carried out. The patient was then transferred to the neonatal intensive care unit (NICU) and treated in a humidified incubator and medicated with intravenous antibiotics (ampicillin sulbactam 125 mg/12 hour and gentamicin 13 mg/24 hour), topically fusidic acid and mild emollients. A central venous catheter was used for intravenous access. The poor prognosis resulted in the patient dying at the age of 5-day-old. This case highlights that prenatal diagnosis is critical for early detection and disease prevention. Mutation screening for the ABCA12 gene is suggested for consanguinity marriages and with a history of ichthyosis.
Evaluation of atopic dermatitis severity using artificial intelligence Maulana, Aga; Noviandy, Teuku R.; Suhendra, Rivansyah; Earlia, Nanda; Bulqiah, Mikyal; Idroes, Ghazi M.; Niode, Nurdjannah J.; Sofyan, Hizir; Subianto, Muhammad; Idroes, Rinaldi
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.511

Abstract

Atopic dermatitis is a prevalent and persistent chronic inflammatory skin disorder that poses significant challenges when it comes to accurately assessing its severity. The aim of this study was to evaluate deep learning models for automated atopic dermatitis severity scoring using a dataset of Aceh ethnicity individuals in Indonesia. The dataset of clinical images was collected from 250 patients at Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia and labeled by dermatologists as mild, moderate, severe, or none. Five pre-trained convolutional neural networks (CNN) architectures were evaluated: ResNet50, VGGNet19, MobileNetV3, MnasNet, and EfficientNetB0. The evaluation metrics, including accuracy, precision, sensitivity, specificity, and F1-score, were employed to assess the models. Among the models, ResNet50 emerged as the most proficient, demonstrating an accuracy of 89.8%, precision of 90.00%, sensitivity of 89.80%, specificity of 96.60%, and an F1-score of 89.85%. These results highlight the potential of incorporating advanced, data-driven models into the field of dermatology. These models can serve as invaluable tools to assist dermatologists in making early and precise assessments of atopic dermatitis severity and therefore improve patient care and outcomes.
An Intriguing Case of Erythroderma Possibly Related to Psoriasis Vulgaris Earlia, Nanda; Umborowati, Menul Ayu; Tasrif, Aqil Yuniawan; Pradistha, Aldilla; Liana, Mahda Rizki; Bulqiah, Mikyal
Indonesian Journal of Case Reports Vol. 1 No. 1 (2023): August 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v1i1.56

Abstract

Erythroderma or generalized exfoliating dermatitis is an inflammatory disease characterized by erythema and thickened scales. A woman, 34 years old, was consulted with complaints of red spots accompanied by blisters and peeling skin almost all over her body for 4 days. Complaints are accompanied by itching and burning sensations. The patient had experienced complaints like this 5 months ago and had been treated at three different hospitals. Physical examination found in the facial region, thorax, superior and inferior right and left extremities, erythematous patches with diffuse borders, thick scales, erosions, and a generalized distribution. The patient's fingernails were found to have a change in shape (pitting nails). Examination of the ANA profile was negative, IgE atopy did not show an allergic reaction to a specific allergen, and histopathological examination was within normal limits. The patient was diagnosed with erythroderma based on psoriasis vulgaris. Treatment includes injection of methylprednisolone, cetirizine 10 mg tablets, and wound care with wet gauze and topical cream. After giving therapy, the patient's clinical improvement. Erythroderma occurs because of an underlying condition and cannot be prevented by itself. Erythroderma because of an underlying inflammatory skin condition usually resolves with treatment but can recur at any time. Overall, the prognosis for erythroderma depends on the underlying cause and is generally good if the underlying disease can be treated effectively.
Comprehensive Treatment Approaches in a Unique Case of Generalized Pustular Psoriasis Earlia, Nanda; Maulida, Mimi; Badiri, Istanul; Pradistha, Aldilla; Bulqiah, Mikyal; Fajrina, Nur
Indonesian Journal of Case Reports Vol. 1 No. 2 (2023): December 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v1i2.113

Abstract

Psoriasis is an immunological inflammatory disease characterized by skin inflammation and epidermal hyperplasia. One type of psoriasis is Generalized Pustular Psoriasis (GPP), which is usually preceded by other diseases. A 56-year-old woman presented to the Department of Dermatology and Venereology with a recent onset of red spots accompanied by pustules distributed across her body. The initial manifestation of these symptoms occurred approximately one month prior, and the condition has progressively worsened over the past three days. Physical examination of dermatological status showed erythematous plaques with smooth, well-defined scales with irregular, round edges, lenticular size, multiple, discrete, and confluent distribution, generalized distribution in the pedis dextra et sinistra, manus dextra et sinistra, and femoral regions. Skin biopsy examination results showed skin tissue with hyperkeratosis, acanthosis, and parakeratosis, with PMN inflammatory cells (Munro's micro abscess). The conclusion of the skin biopsy is pustular psoriasis. The patient was diagnosed with GPP. Patients were given Methotrexate, calcitriol tablets 0.25 mcg twice a day, cetirizine tablets 10 mg twice a day, and topical cream. After one week of treatment, the patient's lesions improved. Treatment continues, and patients are given education to avoid trigger factors such as stress, excessive activity, extreme temperature changes, and focal infections. The management must consider various influencing factors, including genetic factors, skin barriers, predisposing factors, and trigger factors. Prevention is also important. The patient needs to be educated about the details of the disease, how to prevent a recurrence, and treatment when the disease recurs.
Successful Treatment of Burn Wounds with Combined Astaxanthin and Gentamycin Topical: A Serial Case Report Sari, Ninda; Bulqiah, Mikyal
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 3 (2025): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.3.2025.222-227

Abstract

genodermatosis with an estimated incidence of 0.7–1.2 per 100,000 live births. It is caused by mutations in the IKBKG gene. Affected women have a 50% chance of transmitting the defective gene, while male fetuses usually do not survive due to the lethal effect of the mutation. Purpose: This report aims to present a rare surviving male case of incontinentia pigmenti with early dermatological manifestations and to highlight the importance of clinical recognition and multidisciplinary follow-up. Case: A 4-day-old male newborn presented with blisters on the left leg since birth. Dermatological examination showed multiple papules and vesicles arranged along Blaschko’s lines on erythematous macules without erosion. Based on clinical findings, the patient was diagnosed with stage 1 incontinentia pigmenti. Management included the use of moisturizers, topical antibiotics, and parental education regarding potential multi-organ involvement. Regular monitoring for neurological and ophthalmological manifestations was advised. Discussion: Incontinentia pigmenti is caused by an IKBKG gene mutation that disrupts NF-κB signaling, leading to increased apoptosis. It mainly affects ectodermal tissues such as the skin, hair, teeth, eyes, and CNS. The disease progresses through four skin stages: vesiculobullous, verrucous, hyperpigmented, and atrophic/alopecic. Diagnosis is mostly clinical, with histopathology or genetic testing used in atypical cases. Skin lesions usually resolve on their own, but preventing secondary infections is important. Conclusion: Incontinentia pigmenti in male infants is exceedingly rare. Early recognition, supportive care, and vigilant multidisciplinary monitoring are crucial to detect and manage possible systemic complications, improving survival and quality of life.
Co-Authors Asnawi, Vella Badiri, Istanul Budini, Sulamsih S. Doris , Ezigbo E. Dwiyana, Reiva F. Earlia, Nanda Elfa Wirdani Fitri Gondokaryono, Srie P. Handriani, Risna hidayati, Arie Hizir Sofyan Idroes, Ghazi M. Ismida, Fitri Dewi Junaidi, Fachrul Kamarlis, Reno K. Liana, Mahda Rizki Maghfirah, Karamina Maulana, Aga Maulida, Mimi Menul Ayu Umborowati, Menul Ayu Muhammad Subianto Noviandy, Teuku R. NUR FAJRINA Nurdjannah J. Niode Pradistha , Aldilla Pradistha, Aldilla Rinaldi Idroes Rovy Pratama, Rovy Sari, Ninda Suhendra, Rivansyah Tasrif, Aqil Yuniawan Vella, Vella