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Immunostimulant Compounds Identification in Indonesian Underutilized Zingiberaceae Spices Rosalina, Dian; Yuliana, Nancy Dewi; Anggraeni, Ririn; Prangdimurti, Endang
Molekul Vol 18 No 3 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.3.7589

Spices are known for its health beneficial effect beside its function as flavouring and condiment. This study aimed to screen immunostimulant activities of 12 underutilized species of Zingiberaceae grown in Indonesia. The compound associated with immunostimulant activity in the most active sample was identified by linking the chromatogram profile of hexane, chloroform, ethyl acetate, methanol, and water fractions of the selected spices to its activity using orthogonal projection to the least square (OPLS) analysis, followed by LC-MS characterization. The result showed that Alpinia malaccensis and Zingiber ottensii had the highest lymphocyte cell proliferation index (SI) at concentrations of 400 ppm. A. malaccensis was chosen for the next step. The results of OPLS analysis showed that the retention time interval which strongly correlated with the immunostimulant activity was 27.0 – 28.5 minutes, which were abundant in methanol fraction. The mass spectra analysis of methanol fraction using UHPLC-HRMS showed that the respective retention time was attributed to flavokawain B. This compound was reported to increase rat splenocyte proliferation in vivo.

Pembinaan Keagamaan Mualaf di Pesantren Mualaf Indonesia Dompet Dhuafa Rosalina, Dian; Wasil, Wasil
Inklusiva: Jurnal Studi Agama-Agama Vol 2, No 2 (2024): Inklusiva
Publisher : Faculty of Ushuluddin Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/ijsaa.v2i2.42472

This study examines the religious guidance of converts at Pesantren Mualaf Indonesia Dompet Dhuafa through the frameworks of Max Heirich’s conversion theory and Glock and Stark’s religiosity theory. Heirich’s theory is applied to analyze the transformation of spiritual identity and commitment among converts within the pesantren environment. Meanwhile, Glock and Stark’s theory is used to assess the dimensions of belief, practice, experience, and affective religiosity of the converts. The findings indicate that the pesantren's comprehensive approach and intensive support significantly enhance the religiosity and spiritual integration of the converts. This research provides valuable insights into the effectiveness of religious guidance methods in strengthening the religious identity and commitment of new Muslims in the pesantren context.

Optimization of Chitosan Production from Mangrove Crab Shell Waste Using Response Surface Methodology (RSM) Rosalina, Dian; Wijayanti, Willy
Jurnal Teknologi Pengolahan Pertanian Vol 7, No 1 (2025): Jurnal Teknologi Pengolahan Pertanian
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/jtpp.v7i1.12305

This study optimized chitin extraction into chitosan from mangrove crab shells using the Response Surface Methodology (RSM) approach. Three independent factors were used: NaOH concentration (A), deacetylation temperature (B), and deacetylation time (C) at five levels (-α, -1, 0, +1, α). The NaOH concentration ranged from 43.2% to 78.8%, the deacetylation temperature ranged from 83.2°C to 116.8°C, and the deacetylation time ranged from 0.4 hours to 3.6 hours. The dependent variables were yield (Y1), degree of deacetylation (Y2), intrinsic viscosity (Y3), and molecular weight (Y4). The results of chitin deacetylation to chitosan optimization using the Design Expert program with the RSM approach led to 42 optimization formulas. The formula with the highest desirability value of 0.927 was the extraction condition using a 50% NaOH concentration, 110°C deacetylation temperature, and 1 hour deacetylation time. Chitosan obtained under these extraction conditions yielded 33.61%, a deacetylation degree of 79.2%, an intrinsic viscosity of 34.96 ml/g, and a molecular weight of 9.25 kDa. The deacetylation of the chitosan produced met the quality standards from Protan Laboratory, as deacetylation was ≥70%.

Peningkatan Kompetensi Pengelola Website melalui Pelatihan Berbasis Andragogi di Lingkungan Perguruan Tinggi Syahputra, Rizki Agam; Rosalina, Dian; Maliza, Noer Octaviana; Kasmawati, Kasmawati; Safitriyawi, Roja; Lestari, Suci Ayu; Ulfah, Tya
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 6 No. 2 (2025): Jurnal Pengabdian kepada Masyarakat Nusantara Edisi April - Juni
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar

Pelatihan pengelolaan dan pengembangan website di Universitas Teuku Umar bertujuan untuk meningkatkan kompetensi para pengelola website di lingkungan fakultas dan unit kerja universitas. Dalam era digital ini, pengelolaan website yang efektif sangat penting untuk memastikan informasi yang disampaikan selalu up-to-date, menarik, dan mudah diakses oleh mahasiswa, dosen, serta masyarakat umum. Pelatihan ini melibatkan peserta dari berbagai fakultas dan unit kerja yang bertanggung jawab atas pengelolaan website, dengan tujuan untuk memastikan bahwa setiap bagian terkait memiliki keterampilan yang seragam dalam mengelola konten website. Materi pelatihan mencakup pengelolaan konten dan penggunaan sistem WordPress sebagai platform pengelolaan website yang fleksibel dan mudah digunakan. Pelatihan ini juga membahas pengelolaan warna dan konten sesuai dengan standar yang ditetapkan oleh masing-masing instansi. Hasil dari pelatihan menunjukkan bahwa peserta mampu mengatasi tantangan yang dihadapi dalam mengelola website, serta dapat langsung mempraktikkan pengetahuan yang diperoleh, seperti pengeditan konten dan pembaruan tampilan website. Keberhasilan pelatihan ini diharapkan dapat mendukung proses Re-Akreditasi dan peralihan status Universitas Teuku Umar menuju Badan Layanan Umum (BLU), serta memberikan kontribusi positif dalam meningkatkan kualitas pengelolaan website universitas di masa mendatang. Pelatihan ini diharapkan dapat dilanjutkan secara berkala untuk memperkuat kapasitas pengelola website dalam menghadapi perkembangan teknologi digital.

Pembinaan Keagamaan Mualaf di Pesantren Mualaf Indonesia Dompet Dhuafa Rosalina, Dian; Wasil, Wasil
Inklusiva: Jurnal Studi Agama-Agama Vol. 2 No. 2 (2024): Inklusiva
Publisher : Faculty of Ushuluddin Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/ijsaa.v2i2.42472

This study examines the religious guidance of converts at Pesantren Mualaf Indonesia Dompet Dhuafa through the frameworks of Max Heirich’s conversion theory and Glock and Stark’s religiosity theory. Heirich’s theory is applied to analyze the transformation of spiritual identity and commitment among converts within the pesantren environment. Meanwhile, Glock and Stark’s theory is used to assess the dimensions of belief, practice, experience, and affective religiosity of the converts. The findings indicate that the pesantren's comprehensive approach and intensive support significantly enhance the religiosity and spiritual integration of the converts. This research provides valuable insights into the effectiveness of religious guidance methods in strengthening the religious identity and commitment of new Muslims in the pesantren context.

Eksplorasi Potensi Cascara (Cascara) terhadap Kesehatan: Kajian Pustaka Wijayanti, Willy; Rosalina, Dian; Dahlan, Andi; Baihaqi, Baihaqi
Jurnal Minfo Polgan Vol. 14 No. 2 (2025): Artikel Penelitian
Publisher : Politeknik Ganesha Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33395/jmp.v14i2.15679

Cascara, kulit ceri kopi kering, telah menarik minat sebagai makanan fungsional potensial karena konsentrasi senyawa bioaktifnya yang kaya dan manfaat kesehatan yang terkait. Cascara mengandung kadar asam klorogenat, flavonoid, kafein, dan berbagai senyawa fenolik yang signifikan, yang telah dikaitkan dengan sifat antioksidan, anti-inflamasi, dan pengatur metabolisme. Selain itu, cascara mengandung serat larut yang meningkatkan kesehatan usus dengan meningkatkan pencernaan dan bertindak sebagai prebiotik, yang mendorong mikrobioma usus yang seimbang. Penelitian-penelitian mengenai pemanfaatan cascara, khususnya dalam pembuatan minuman seperti kombucha cascara, menyoroti keserbagunaannya sebagai bahan makanan fungsional. Proses fermentasi ini tidak hanya meningkatkan ketersediaan hayati senyawa-senyawa bermanfaatnya, tetapi juga menciptakan profil rasa yang unik, menarik bagi konsumen yang peduli kesehatan. Selain itu, aspek keberlanjutan dalam memanfaatkan cascara, produk sampingan dari pengolahan kopi, berkontribusi pada pengurangan limbah dalam industri kopi sekaligus memberikan nilai gizi. Meningkatnya minat pada produk alami dan peningkat kesehatan membuka jalan baru bagi cascara, menekankan potensi perannya dalam strategi kesehatan preventif. Dengan demikian, cascara merupakan tambahan yang berharga bagi praktik diet, menawarkan manfaat lingkungan dan sifat-sifat yang signifikan untuk meningkatkan kesehatan. Oleh karena itu, cascara muncul sebagai kandidat yang menjanjikan untuk eksplorasi lebih lanjut dalam penelitian klinis dan nutrisi, yang memerlukan minat lebih besar untuk aplikasinya dalam meningkatkan kesehatan masyarakat,

Profil Metabolit Volatil dan Non Volatil Bangle Hitam Wardayanie, Ning Ima Arie; Prangdimurti, Endang; Hunaefi, Dase; Batubara, Irmanida; Tunnisa , Fitra; Rosalina, Dian; Afriyanti , Ani; Yuliana , Nancy Dewi
Jurnal Teknologi dan Industri Pangan Vol. 36 No. 2 (2025): Jurnal Teknologi dan Industri Pangan
Publisher : Perhimpunan Ahli Teknologi Pangan Indonesia bekerjasama dengan Departemen Ilmu dan Teknologi Pangan, IPB University Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.6066/jtip.2025.36.2.208

The study discovering chemical compounds of black bangle (Zingiber ottensii Val.), which is a member of Zingiberaceae family, is rather scarce. This research aimed to determine the composition of volatile dan non-volatile compounds of the rhizome. The volatile compound was analyzed using solid phase microextraction gas chromatography mass spectrometry (SPME GC-MS), while non-volatile compound was determined by Ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS). The experiment by SPME GC-MS successfully identified 31 compounds with monoterpenes showing the most abundant group at 54 %. The main volatile compounds are β-Phellandrene, β-pinene, γ-Terpinene and α-pinene, then followed by sesquiterpene and terpene, namely humulene and terpinen-4-ol, respectively. Furthermore, analysis using UHPLC-HRMS detected 37 compounds with some pre dominant compounds, i.e. zerumbone, choline, isoleucine, phenylalanine, afzelin and malic acid. These findings indicate that black bangle rhizome is rich in various volatile and non-volatile compounds, especially terpenoid, flavonoid, amino acid and malic acid, some of which have certain bioactivities.

Dampak Deep-Fat Frying Berulang terhadap Degradasi Minyak dan Transformasi Mutu Organoleptik Singkong Goreng Agustina, Nur Ariyani; Rosalina, Dian
Jurnal Pertanian Khairun Vol 4, No 2: (Desember 2025)
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/jpk.v4i2.11030

This study aims to evaluate the effects of repeated cassava frying using the deep-fat frying method at 180°C on the physicochemical and sensory quality of Red Palm Oil and Palm Oil. The experiment employed a two-factor Completely Randomized Design (CRD) consisting of five frying repetitions and two types of oil. The analytical parameters assessed included peroxide value, moisture content, free fatty acid (FFA) content, impurity level, and organoleptic attributes (taste, texture, aroma, and color). The findings demonstrated that repeated frying exerted a significant influence (p 0.05) on both oils, particularly in terms of moisture content, FFA concentration, and peroxide value. Sensory evaluation indicated that cassava fried in Red Palm Oil consistently achieved higher scores for texture, aroma, and color compared to that fried in Palm Oil. Moreover, the interaction between oil type and frying frequency showed a statistically significant effect on the measured parameters. Red Palm Oil exhibited superior oxidative stability relative to Palm Oil and maintained favorable sensory characteristics up to the second frying cycle. Based on these results, it can be concluded that using oil more than two to three times during deep-fat frying markedly decreases oil quality and may compromise the sensory attributes of the resulting fried products.

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