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The Effect of Administering Kelor Flower (Moringa Oleifera) Extract on Reducing Cholesterol Levels and Histopathological Features of The Testis of White Rats (Rattus norvegicus) Male Wistar Strain Obesity Irawan, Muhammad Andi; Tarigan, Antje Irmella; Dalimunthe, Siti Aisyah
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.756

Abstract

Obesity and high cholesterol levels have garnered clinical attention for male infertility. The numerous compounds in Kelor flowers or Moringa make it a potential cholesterol medication. The research data were analyzed using SPSS, and the study was conducted as a true experiment using test animal samples of twenty-four male Wistar rats (Rattus norvegicus). The purpose of this study was to examine the histopathological features of obese male Wistar rats (Rattus norvegicus) and to determine whether or not the administration of Kelor flower extract (Moringa ternatea) reduced cholesterol levels and improved testicular function. Obese white Wistar rats had their total cholesterol levels decreased by 400 mg/kgBW and 600 mg/kgBW of Kelor flower extract, respectively, according to the study's results. The group that received 600 mg/kgBW of Kelor flower extract showed the most improvement and was the most similar to the control group in testicular histopathology studies. The substances found in Kelor or Moringa flowers have been found to improve testicular function and lower total cholesterol levels in people who suffer from obesity, according to the research.
Early menopause and type 2 diabetes: A cross-sectional study at Royal Prima Hospital Waren, N Wignes; Wijaya, Johanna Fransisca; Dalimunthe, Siti Aisyah
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5606

Abstract

Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting various organs and causing hormonal disorders. Estrogen deficiency can alter a woman's menstrual cycle and trigger menopause, which affects reproductive health, fat distribution, lipid profiles, and the nervous system. This study aimed to assess the relationship between T2DM and menopausal age in women in the menopausal phase. The research method used was observational with a cross-sectional design, using 120 medical records of menopausal women from the period 2020-2022 at the Royal Prima Hospital. To explore the relationship between menopausal age and T2DM, bivariate analysis was performed, including the Chi-square test or Fisher's Exact Test for categorical variables, as well as t-test or Mann-Whitney U test for numerical variables. The results showed that the age range of 51-60 years constituted the largest group of 120 T2DM patients (29.17%). The most common age of onset of menopause was between 46-50 years, and showed a significant influence on the risk of T2DM (sig value 0.026 and t value 2.257). Blood pressure, which varied from 81 mmHg to 283 mmHg, showed no significant association with T2DM. It can be concluded that age at the onset of menopause was significantly associated with the risk of T2DM, whereas blood pressure had no significant effect on T2DM in this study. These findings highlight the importance of health monitoring in women with early menopause to prevent the development of T2DM.
Early menopause and type 2 diabetes: A cross-sectional study at Royal Prima Hospital Waren, N Wignes; Wijaya, Johanna Fransisca; Dalimunthe, Siti Aisyah; Kuswani, Lili; Riskaldy, Riskaldy; Munadi, Munadi
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5606

Abstract

Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting various organs and causing hormonal disorders. Estrogen deficiency can alter a woman's menstrual cycle and trigger menopause, which affects reproductive health, fat distribution, lipid profiles, and the nervous system. This study aimed to assess the relationship between T2DM and menopausal age in women in the menopausal phase. The research method used was observational with a cross-sectional design, using 120 medical records of menopausal women from the period 2020-2022 at the Royal Prima Hospital. To explore the relationship between menopausal age and T2DM, bivariate analysis was performed, including the Chi-square test or Fisher's Exact Test for categorical variables, as well as t-test or Mann-Whitney U test for numerical variables. The results showed that the age range of 51-60 years constituted the largest group of 120 T2DM patients (29.17%). The most common age of onset of menopause was between 46-50 years, and showed a significant influence on the risk of T2DM (sig value 0.026 and t value 2.257). Blood pressure, which varied from 81 mmHg to 283 mmHg, showed no significant association with T2DM. It can be concluded that age at the onset of menopause was significantly associated with the risk of T2DM, whereas blood pressure had no significant effect on T2DM in this study. These findings highlight the importance of health monitoring in women with early menopause to prevent the development of T2DM.
The Effect of Administering Kelor Flower (Moringa Oleifera) Extract on Reducing Cholesterol Levels and Histopathological Features of The Testis of White Rats (Rattus norvegicus) Male Wistar Strain Obesity Irawan, Muhammad Andi; Tarigan, Antje Irmella; Dalimunthe, Siti Aisyah
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.756

Abstract

Obesity and high cholesterol levels have garnered clinical attention for male infertility. The numerous compounds in Kelor flowers or Moringa make it a potential cholesterol medication. The research data were analyzed using SPSS, and the study was conducted as a true experiment using test animal samples of twenty-four male Wistar rats (Rattus norvegicus). The purpose of this study was to examine the histopathological features of obese male Wistar rats (Rattus norvegicus) and to determine whether or not the administration of Kelor flower extract (Moringa ternatea) reduced cholesterol levels and improved testicular function. Obese white Wistar rats had their total cholesterol levels decreased by 400 mg/kgBW and 600 mg/kgBW of Kelor flower extract, respectively, according to the study's results. The group that received 600 mg/kgBW of Kelor flower extract showed the most improvement and was the most similar to the control group in testicular histopathology studies. The substances found in Kelor or Moringa flowers have been found to improve testicular function and lower total cholesterol levels in people who suffer from obesity, according to the research.
The Relationship Between Screen Time and Nutritional Status of Children at SDN 060838 Medan in 2024 Siregar, Anggi Dolse Maria; Yasirah, Tarisya; Dalimunthe, Siti Aisyah; Wijaya, Johanna Fransiska
J-Kesmas: Jurnal Fakultas Kesehatan Masyarakat (The Indonesian Journal of Public Health) Vol 11, No 2 (2024): Oktober 2024
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/j-kesmas.v11i2.10373

Abstract

Excess weight in children and adolescents is a global health problem that can result in various serious complications. One of the main factors that trigger obesity is lack of physical activity, which is largely influenced by the length of time using screen devices. Screen use of more than two hours a day has been linked to increased sedentary behavior, decreased physical activity, disrupted sleep patterns, and unhealthy eating patterns, all of which contribute significantly to the risk of obesity. This study aims to assess the relationship between duration of screen use and nutritional status among students at SDN 060838 in Medan City. With a cross-sectional analytical research design, the sample used was 50 students selected from a population of 198 students. Data were analyzed using the Mann-Whitney test, which showed a statistically significant relationship between screen time duration and nutritional status (p < 0.001). These results emphasize the importance of managing screen time as a key element in preventing obesity in children. Appropriate policies and guidelines are needed to support their health and well-being, especially amidst the increasing use of screen devices for social and educational needs.