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Pengaruh Pemberian Ekstrak Buah Pala (Myrisca Fragnant Houtt) Terhadap Proses Penyebuhan Luka Sayat Dan Hispatologi Jaringan Kulit Tikus Putih Galur Wistar Jantan Yang Mengalami Diabetes Melitus Josika, Winita; Riskaldy, Riskaldy; Sherliana, Ferra
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.756

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak buah pala (Myristica fragrans Houtt) terhadap proses penyembuhan luka dan gambaran histopatologi jaringan kulit pada tikus putih jantan galur Wistar yang menderita diabetes melitus. Induksi diabetes melitus dilakukan dengan pemberian aloksan dan tikus dibagi menjadi beberapa kelompok, yaitu kelompok kontrol, kelompok diabetes, dan kelompok perlakuan yang diberi ekstrak buah pala dengan dosis yang berbeda-beda. Proses penyembuhan luka dievaluasi dengan mengukur waktu penyembuhan dan perubahan ukuran luka, sedangkan pemeriksaan histopatologi jaringan kulit dilakukan dengan pewarnaan hematoksilin dan eosin. Hasil penelitian menunjukkan bahwa pemberian ekstrak buah pala secara bermakna mempercepat proses penyembuhan luka dan memperbaiki gambaran histopatologi jaringan kulit yang rusak akibat diabetes melitus. Ekstrak buah pala terbukti berpotensi dalam mendukung proses penyembuhan luka pada tikus diabetes.
Factors influencing the participation of mothers with toddlers in posyandu activities in Kemenangan Tani Village, Medan Tuntungan District Mujahidin, Mujahidin; Wenti Anggraeni, Wenti; Daeli, Elisa Hotmauli Gratia; Sabri, Ihsan; Ivonne, Ivonne; Muchtar, Muhammad Arafat; Riskaldy, Riskaldy; Dewani , Yunita; Ferdinand, Sahna; Mukhtar, Zulfikri; Reza, Faisal
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7442

Abstract

Posyandu is a type of community-based health effort (UKBM) which is managed and organized by, for, and with the community in the implementation of health development. Empowering the community to obtain essential health services, accelerating the reduction of maternal and child mortality. This study aims to determine the relationship between knowledge and characteristics of mothers under five with visits to posyandu activities in Kelurahan Kemenangan Tani. This research is an analytic survey with a cross-sectional approach. The population in this study were mothers of children under five at the Kelurahan Kemenangan Tani Posyandu. The sample in this study was 60 respondents with the determination of the number of samples using the slovin formula. The sampling technique used is proportional random sampling with inclusion and exclusion criteria. Data was collected through interviews using a questionnaire. This study used the chi-square statistical test (Confidance Interval (CI) 95%; = 0.05). Multivariate analysis using logistic regression. The results of this study indicate that there is a significant relationship between mother's knowledge and mother's characteristics with the visit of mothers under five in posyandu activities (p < 0.05). The dominant independent variable was education (p= 0.011; PR= 14,903, 95% CI = 1,872-118,660). The conclusion of this study is that there is a significant relationship between mother's knowledge and mother's characteristics with the visit of mothers under five in posyandu activities. The dominant independent variable is education.
Early menopause and type 2 diabetes: A cross-sectional study at Royal Prima Hospital Waren, N Wignes; Wijaya, Johanna Fransisca; Dalimunthe, Siti Aisyah; Kuswani, Lili; Riskaldy, Riskaldy; Munadi, Munadi
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5606

Abstract

Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting various organs and causing hormonal disorders. Estrogen deficiency can alter a woman's menstrual cycle and trigger menopause, which affects reproductive health, fat distribution, lipid profiles, and the nervous system. This study aimed to assess the relationship between T2DM and menopausal age in women in the menopausal phase. The research method used was observational with a cross-sectional design, using 120 medical records of menopausal women from the period 2020-2022 at the Royal Prima Hospital. To explore the relationship between menopausal age and T2DM, bivariate analysis was performed, including the Chi-square test or Fisher's Exact Test for categorical variables, as well as t-test or Mann-Whitney U test for numerical variables. The results showed that the age range of 51-60 years constituted the largest group of 120 T2DM patients (29.17%). The most common age of onset of menopause was between 46-50 years, and showed a significant influence on the risk of T2DM (sig value 0.026 and t value 2.257). Blood pressure, which varied from 81 mmHg to 283 mmHg, showed no significant association with T2DM. It can be concluded that age at the onset of menopause was significantly associated with the risk of T2DM, whereas blood pressure had no significant effect on T2DM in this study. These findings highlight the importance of health monitoring in women with early menopause to prevent the development of T2DM.
Factors influencing the participation of mothers with toddlers in posyandu activities in Kemenangan Tani Village, Medan Tuntungan District Mujahidin, Mujahidin; Wenti Anggraeni, Wenti; Daeli, Elisa Hotmauli Gratia; Sabri, Ihsan; Ivonne, Ivonne; Muchtar, Muhammad Arafat; Riskaldy, Riskaldy; Dewani , Yunita; Ferdinand, Sahna; Mukhtar, Zulfikri; Reza, Faisal
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7442

Abstract

Posyandu is a type of community-based health effort (UKBM) which is managed and organized by, for, and with the community in the implementation of health development. Empowering the community to obtain essential health services, accelerating the reduction of maternal and child mortality. This study aims to determine the relationship between knowledge and characteristics of mothers under five with visits to posyandu activities in Kelurahan Kemenangan Tani. This research is an analytic survey with a cross-sectional approach. The population in this study were mothers of children under five at the Kelurahan Kemenangan Tani Posyandu. The sample in this study was 60 respondents with the determination of the number of samples using the slovin formula. The sampling technique used is proportional random sampling with inclusion and exclusion criteria. Data was collected through interviews using a questionnaire. This study used the chi-square statistical test (Confidance Interval (CI) 95%; = 0.05). Multivariate analysis using logistic regression. The results of this study indicate that there is a significant relationship between mother's knowledge and mother's characteristics with the visit of mothers under five in posyandu activities (p < 0.05). The dominant independent variable was education (p= 0.011; PR= 14,903, 95% CI = 1,872-118,660). The conclusion of this study is that there is a significant relationship between mother's knowledge and mother's characteristics with the visit of mothers under five in posyandu activities. The dominant independent variable is education.