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Vitamin K Supplementation for Reducing Cardiovascular Events in End-Stage Chronic Kidney Disease: A Systematic Review Liora, Kevin; Wiyono, Putri Dhiya Prameswari; Putra, Ananda; Alexander, Devin; Ramadhan, Afif; Oktavia, Anissya Rima; Larissa, Olivia; Nugroho, Fajar Prianto; Tjahyanto, Teddy
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 1 (2024): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i1.919

Abstract

This study was conducted to analyze the hSIL of Vitamin K Supplementation in Reducing Cardiovascular Events in End-Stage Chronic Kidney Disease: A Systematic Review. Cardiovascular disease (CVD) is the leading source of morbidity and mortality worldwide, and chronic kidney disease (CKD) is a major contributor to this matter. Kidney disease is estimated to affect over 850 million people worldwide. The present systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. We searched studies from electronic databases (PubMed Central, ScienceDirect, PLoS One, Google Scholar, Nature). Studies were considered eligible if they met the following criteria : (1) the study is a randomized controlled trial (RCT), (2) the study was published in the last 5 years (2018– 2022), (3) the study participants were adult patients with kidney disease from stage III to end-stage who were given vitamin K supplementation, (4) the study reported coronary artery calcium scores pre- and post- vitamin K supplementation, (5) the study was published in English. Risk of bias of each study was evaluated using Cochrane Risk of Bias (RoB) 2 tool. Data were descriptively examined and narratively reported. In conclusion, our results do not suggest that vitamin K supplementation may affect vascular calcification as measured by the CAC score. Up till now there is no treatment to reverse vascular calcification in ESKD patients. The current clinical practice should focus on prevention and retardation of its progression.
Management of Palpebra Rupture Cases in Children: A Case Report Syawali, Milenia; Juwita, Oktarina Nila; Oktavia, Anissya Rima
Jurnal Impresi Indonesia Vol. 4 No. 4 (2025): Indonesian Impression Journal (JII)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i4.6408

Abstract

Eyelid injuries, particularly palpebral lacerations, are common in pediatric patients and require meticulous management to prevent long-term functional and cosmetic issues. These injuries, often resulting from trauma, pose significant challenges, as they involve both the skin and deeper structures of the eyelid. This case report discusses the management of a 7-year-11-month-old child who sustained a full-thickness eyelid laceration after falling and hitting a stone. The patient presented with sharp pain, difficulty in opening the eyelid, and bleeding. A physical examination revealed a full-thickness laceration on the superior margin of the left eyelid, with accompanying edema and subconjunctival hemorrhage. Imaging tests were not required as no orbital injury was suspected. The patient underwent eyelid reconstruction within 72 hours, and postoperative care included antibiotic treatment and wound management. The surgical outcome was successful, with optimal cosmetic and functional results. This case underscores the importance of timely and precise surgical intervention to minimize complications and achieve satisfactory results in pediatric palpebra injuries. Further research is needed to establish comprehensive guidelines for managing eyelid trauma in children, particularly regarding surgical techniques and postoperative care to ensure the best outcomes for young patients.