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All Journal Syntax Literate: Jurnal Ilmiah Indonesia JOURNAL SPORT AREA Medicinus : Jurnal Kedokteran Health Information : Jurnal Penelitian Jurnal Manajemen Bisnis dan Kewirausahaan Jurnal Health Sains KESANS : International Journal of Health and Science International Journal of Public Health Excellence (IJPHE)
Tjahyanto, Teddy
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Humanities Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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HUBUNGAN KECERDASAN EMOSIONAL TERHADAP TINGKAT DEPRESI MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS TARUMANAGARA Tjahyanto, Teddy
Jurnal Health Sains Vol. 2 No. 7 (2021): Jurnal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v2i7.254

Abstract

World Health Organization (WHO) secara resmi mendeklarasikan COVID-19 sebagai pandemi yang menjadi problema kesehatan di dunia. Pembatasan sosial dan kebijakan pemerintah lainnya yang diberlakukan selama pandemi COVID-19 untuk menurunkan penyebaran virus yang sangat menular menyebabkan banyak orang mengalami kesepian, ketakutan, kecemasan dan berakhir pada depresi. Prevalensi depresi di Indonesia saat pandemi COVID-19 mencapai angka 62%. Kecerdasan emosional merupakan kemampuan dalam mengatur dan mengontrol emosi yang dapat berperan dalam menyikapi kebijakan selama pandemi COVID-19 dan kejadian depresi. Penelitian dilakukan untuk mengetahui hubungan antara kecerdasan emosional dengan depresi pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara angkatan 2019. Menggunakan desain penelitian deskriptif analitik dengan pendekatan cross-sectional, kami memperoleh data melalui simple random sampling sebanyak 154 responden yang menjawab kuesioner kecerdasan emosional yang digunakan sebagai proksi dalam menentukan skala kecerdasan emosional. Hasil chi-square hubungan kecerdasan emosional dengan depresi didapatkan p-value 0.003. Berdasarkan hasil penelitian didapatkan bahwa terdapat hubungan yang bermakna antara kecerdasan emosional dan depresi pada mahasiswa saat pandemi COVID-19. Oleh karena itu, diharapkan mahasiswa dapat meningkatkan kecerdasan emosional yang mereka miliki sebagai upaya preventif akan terjadinya depresi.
Peran Mikrobiota Saluran Cerna pada Artritis Reumatoid Tjahyanto, Teddy; Eldy, Eldy; Felicia, Clarissa; Niaga, Karmenia Jessica Kurnia
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (602.799 KB) | DOI: 10.36418/syntax-literate.v6i11.4568

Abstract

Artritis rheumatoid merupakan suatu penyakit autoimun yang ditandai dengan adanya proses inflamasi kronis sistemik dan berakibat pada kerusakan sendi. Mekanisme etiopatogenik yang menyebabkan inflamasi yang sangat kompleks dan melibatkan berbagai faktor, termasuk keseimbangan mikrobiota saluran cerna. Tujuan penelitian dilakukan untuk meninjau lebih dalam mengenai peran interaksi inang-mikrobiota terhadap sistem kekebalan inang, mendiskusikan kemungkinan hubungan patofisiologi antara disbiosis mikrobiota saluran cerna dan manifestasi, serta menyarankan langkah preventif dan terapi potensial untuk artritis rheumatoid melalui perbaikan disbiosis mikrobiota saluran cerna. Sumber literatur diambil dari artikel jurnal yang dipublikasikan secara online dalam rentang waktu tahun 2016-2021. Database yang digunakan adalah PubMed, Science Direct, Cochrane, dan Wiley. Penelitian menunjukkan adanya korelasi yang kuat antara disbiosis dan inflamasi mukosa saluran cerna dengan patogenesis artritis reumatoid. Disbiosis mikrobiota saluran cerna menyebabkan terbentuknya imunotoleransi yang berakibat pada penyakit autoimun. Peran mikrobiota pada artritis rheumatoid meliputi produksi sitokin proinflamasi dan sel Th17, serta pembentukan autoantibodi ACPA. Metabolit anti inflamasi mikrobiota seperti butirat yang meregulasi keseimbangan TFH/TFR didapatkan menurun pada artritis reumatoid. Disbiosis mikrobiota saluran cerna telah terbukti menjadi salah satu faktor penting dalam manifestasi artritis rheumatoid pada model hewan. Studi tambahan perlu dilakukan untuk mengeksplorasi keterlibatan mikrobiota dalam saluran cerna yang berbeda dalam modulasi imun selama patogenesis artritis reumatoid.
Risiko Paparan Asap Rokok Pada Ibu Hamil Terhadap Kejadian Penyakit Paru Anak : Tinjauan Pustaka Syarifah, Anisa Ulaya; Riskyana, Claudya Dwie; Tjahyanto, Teddy
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kesehatan pada masa kehamilan harus dijadikan perhatian khusus pada ibu hamil karena memiliki pengaruh terhadap kesehatan janin dan anak di masa mendatang. Terutama pengaruh paparan asap rokok pada lingkungan yang menjadi salah satu faktor risiko penyakit saluran pernapasan. Dalam hal ini Secondhand Smoke (SHS) memiliki pengaruh kuat yang dapat berdampak pada gangguan perkembangan janin seperti pada organ paru, Berat Bayi Lahir Rendah (BBLR), peningkatan kejadian ISPA, dll. Penelitian ini dilakukan untuk mengetahui dan menyimpulkan zat SHS yang berdampak pada perkembangan dan penyakit paru anak. Penulis melakukan pencarian, pemilahan dan analisis literatur-literatur ilmiah dengan kata kunci exposure tobacco smoke, pregnancy, prenatal, maternal, respiratory tract disease, children. Sumber literatur yang digunakan adalah google scholar, pubmed, science direct dengan jangka waktu 10 tahun terakhir (2012-2022). Hal yang paling penting dalam SHS yaitu zat yang terkandung dalam asap rokok yang dihirup oleh ibu hamil. Terdapat tiga jenis zat yang memiliki mekanisme kuat yang mempengaruhi janin, diantaranya Karbon Monoksida menyebabkan kurangnya pasokan oksigen pada darah bayi melalui plasenta sehingga dapat menyebabkan cacat lahir, dll. Nikotin yang mempengaruhi perkembangan paru janin dengan nAChRs (reseptor asetilkolin nikotinat) dan mengurangi aktivitas enzim antioksidan dan Polycyclic Aromatic Hydrocarbons (PAHs) yang dapat menimbulkan asma pada anak dengan memodulasi metilasi DNA dari gen pertumbuhan melalui plasenta ibu. Dari ketiga jenis zat tersebut dapat disimpulkan bahwa SHS berpengaruh kuat terhadap perkembangan dan penyakit paru anak dengan mekanisme sama yaitu dapat melewati plasenta. Namun, mengenai dampak langsung atau terdapat durasi rentang dari prenatal ke postnatal penyakit paru pada anak belum didapatkan laporan pasti, diharapkan pada penelitian selanjutnya dapat menguraikan lebih lanjut.
The Effectiveness of Using Laser Therapy on Outcome of Carpal Tunnel Syndrome Patients : A Literature Review Tjahyanto, Teddy; Mayung, Claraiva; Yohanes, Guntur; Erwin, Ferdinand; Wiracakra, I Gusti Lanang Krisna
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 1 (2023): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i1.523

Abstract

Carpal Tunnel Syndrome (CTS) is a neuropathy caused by compression of the median nerve that passes through the carpal tunnel structure in the wrist. If the CTS condition is not treated, complications will occur such as irreversible damage to the median nerve resulting in permanent impairment and disability, chronic wrist pain, and muscle atrophy and weakness. Currently there are various CTS therapies such as splinting , local injection of corticosteroids, oral medications such as prednisone, physical therapy such as carpal bone mobilization, ultrasound therapy , and nerve glides exercises , as well as surgical therapy. However, these various therapies have not provided optimal results and there are complications such as neuromas, hypertrophic wounds, dysesthesia, wrist joint stiffness, and the inability of various to reduce CTS symptoms. Therefore, more effective therapy with minimal side effects is needed. Therefore, in this literature review, an analysis of the effect of laser therapy on various outcomes of CTS patients as an innovative therapy was carried out. Study searches were performed on various databases such as Pubmed, ScienceDirect , Directory of Open Access Journal , Epistemonikos, and Cochrane Library . From the search results obtained a total of 389 studies. The 7 studies that met the inclusion and exclusion criteria were the studies that were analyzed in this literature review. Various types of laser therapy showed better outcome results than the control group, with LLLT laser therapy showing the best results in various outcomes in CTS patients. LLLT laser therapy also shows better results when combined with other types of therapy. No adverse events were reported with any type of laser therapy in all inclusion studies. Therapy is the newest type of innovative therapy with better effects and minimal side effects compared to conventional therapy in CTS patients.
Vitamin K Supplementation for Reducing Cardiovascular Events in End-Stage Chronic Kidney Disease: A Systematic Review Liora, Kevin; Wiyono, Putri Dhiya Prameswari; Putra, Ananda; Alexander, Devin; Ramadhan, Afif; Oktavia, Anissya Rima; Larissa, Olivia; Nugroho, Fajar Prianto; Tjahyanto, Teddy
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 1 (2024): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i1.919

Abstract

This study was conducted to analyze the hSIL of Vitamin K Supplementation in Reducing Cardiovascular Events in End-Stage Chronic Kidney Disease: A Systematic Review. Cardiovascular disease (CVD) is the leading source of morbidity and mortality worldwide, and chronic kidney disease (CKD) is a major contributor to this matter. Kidney disease is estimated to affect over 850 million people worldwide. The present systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. We searched studies from electronic databases (PubMed Central, ScienceDirect, PLoS One, Google Scholar, Nature). Studies were considered eligible if they met the following criteria : (1) the study is a randomized controlled trial (RCT), (2) the study was published in the last 5 years (2018– 2022), (3) the study participants were adult patients with kidney disease from stage III to end-stage who were given vitamin K supplementation, (4) the study reported coronary artery calcium scores pre- and post- vitamin K supplementation, (5) the study was published in English. Risk of bias of each study was evaluated using Cochrane Risk of Bias (RoB) 2 tool. Data were descriptively examined and narratively reported. In conclusion, our results do not suggest that vitamin K supplementation may affect vascular calcification as measured by the CAC score. Up till now there is no treatment to reverse vascular calcification in ESKD patients. The current clinical practice should focus on prevention and retardation of its progression.
Yo-Yo Intermitten Recovery Test: A study of football players’ VO2max physical condition Suryadi, Didi; Yanti, Novi; Tjahyanto, Teddy; Ramli; Rianto, Louis
Journal Sport Area Vol 8 No 2 (2023): August
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2023.vol8(2).12392

Abstract

The Yo-Yo Intermittent Recovery Test is frequently used to evaluate VO2max and is crucial for determining an athlete's physical condition. However, its effectiveness in accurately assessing the physical condition of football players remains limited. This study aims to analyze the level of the physical condition of football players' VO2max which will be used as evaluation material for designing training programs so that the pattern of coaching becomes focused and produces achievements. This research used a quantitative approach to the survey method. The subjects of this study were Pusaka FC football club athletes, the sampling technique used total sampling so that all athletes were a sample of 23 players. The test instrument used the Yo-Yo Intermitten Recovery Test level 2. Data analysis used descriptive percentages, with the assistanceof the Microsoft Excel 2019 software application. The results of the study show that the VO2max level value in soccer athletes is 13.04% of athletes in the poor category and 34.78% in the good category. Below average, 47.82% shows the average category, and there is only 4.35%, which shows the value of the good category. Based on the results of the VO2max ability test, the average classification of Club Pusaka FC players is still relatively low. However, it is necessary to know that the limitations of this study lie in the condition of the players' nutritional intake which has not been controlled and their age which must also be taken into consideration by researchers. Furthermore, it can find information on the effect of athlete nutrition on endurance ability.
Characteristics of COVID-19 Therapy Based on Disease Severity at Siloam Kebon Jeruk Hospital Tjahyanto, Teddy; Herwanto, Velma
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9233

Abstract

Introduction : COVID-19 is an infectious disease that can cause acute respiratory syndrome by droplet transmission. Along with the very fast spread of the virus which occurs in almost all countries, it is necessary to have therapies that can reduce the morbidity and mortality of patients infected with COVID-19. Various factors affect the administration of therapy so a management guideline is needed for medical personnel so that the administration of therapy can be consistent and efficient in accordance with scientific evidence. This study aims to determine the characteristics and therapeutic options of COVID-19 patients based on the severity of the disease so it can be an evaluation for policymakers and health workers in providing COVID-19 therapy. Methods : This type of research is descriptive, and the research design is cross-sectional with a total population sampling. The study was conducted at Siloam Kebon Jeruk Hospital with a total of 135 respondents from secondary medical record data. Results : The observed data include the characteristics of the respondents and the therapies for COVID-19 patients, which consist of antiviral, anti-inflammatory, and anticoagulant treatments. Based on the collected data, COVID-19 patients were predominantly male (55.6%) with an average age of 55 years. Many patients presented with moderate severity without requiring oxygen (34.1%) and were classified as having referred outcomes (47.4%). Antiviral therapy using favipiravir was predominantly administered to patients with mild to moderate severity, while remdesivir was mostly given to those with moderate to severe severity. Corticosteroids, such as dexamethasone and methylprednisolone, were the preferred choice for anti-inflammatory therapy (72.2%). Heparin was the most commonly used anticoagulant therapy across all severity levels, and antibiotics were administered to the majority of patients infected with COVID-19 (73.3%). Conclusions : Evaluation of the low rate of use of corticosteroids and anticoagulants in COVID-19 patients is needed.
Predictive Value of Optic Nerve Sheath Diameter in Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis Tjahyanto, Teddy; Suryakanto, Milani
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9240

Abstract

Introduction : Optic nerve sheath diameter (ONSD) is a promising non-invasive marker for elevated intracranial pressure (ICP), potentially aiding in the prognostication of subarachnoid hemorrhage (SAH) outcomes. This study aimed to evaluate the predictive value of ONSD for poor outcomes in SAH patients, defined by the Glasgow Outcome Scale (GOS). Methods : A systematic review and meta-analysis were conducted, including studies from 2010 to 2021 that examined the relationship between ONSD and outcomes in SAH patients. A total of 615 patients were analyzed, with mean ages ranging from 54.1 to 58.8 years, and a predominance of males (38.2%). SAH severity was stratified using the Hunt and Hess classification, ranging from Grade 1 to Grade 5. The QUADAS-2 tool assessed the risk of bias, and the GRADE framework evaluated evidence certainty. Results : The pooled analysis revealed moderate predictive accuracy for ONSD in determining poor outcomes, with a pooled proportion of 0.70 (95% CI: 0.61–0.78). Significant heterogeneity (I² = 77.4%, p = 0.004) was observed, likely due to variability in ONSD thresholds, measurement techniques, and timing. Funnel plot analysis suggested potential publication bias, although further statistical testing is needed. Conclusions : ONSD demonstrates potential as a non-invasive tool for predicting poor outcomes in SAH patients. However, significant heterogeneity and moderate accuracy highlight the need for standardization of ONSD thresholds and measurement protocols. Further multicenter studies are required to validate its clinical utility and integrate it into comprehensive prognostic models.
COX-2 Expression and Its Prognostic Implications in Uterine Leiomyosarcoma: A Systematic Review and Meta-Analysis Suherman, Levita Dyah Kartika; Sungkarto, Kenny; Ellyamurti, Devanti Octavia; Tarigan, Tiara Namora; Negara, Puspa; Tjahyanto, Teddy; Wijaya, Jeremiah Hilkiah
Medicinus Vol. 14 No. 2 (2025): February
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i2.9547

Abstract

Background : Uterine leiomyosarcoma (ULMS) is a rare, aggressive malignancy with high recurrence and poor survival, necessitating prognostic biomarkers and therapeutic targets. Cyclooxygenase-2 (COX-2), implicated in tumorigenesis and angiogenesis, remains understudied in ULMS. This systematic review and meta-analysis assessed COX-2’s prognostic role in ULMS. Methods : Following PRISMA guidelines, six studies (n=185) were retrieved from PubMed, EMBASE, and Scopus (2001–2024). Inclusion criteria required ULMS cohorts with COX-2 expression data and survival outcomes. Risk of bias was assessed using QUADAS-2, and evidence certainty via GRADE. A random-effects meta-analysis calculated pooled effect estimates with 95% confidence intervals (CIs), while heterogeneity was evaluated using I² statistics. Result : COX-2 expression correlated moderately with epithelial components (pooled effect: 0.51, 95% CI: 0.26–0.77) and weakly with mesenchymal components (0.26, 95% CI: 0.06–0.45). High heterogeneity (I² = 89.5% and 82.2%) reflected differences in study design, tumor subtypes, and COX-2 measurement thresholds. QUADAS-2 indicated a low risk of bias, and GRADE confirmed high evidence certainty. Stronger epithelial correlations were observed in Asian cohorts, highlighting geographic variability. Conclusions: COX-2 plays a more significant role in epithelial-driven ULMS carcinogenesis. Despite heterogeneity, robust methodologies support these findings. Future studies should standardize COX-2 assessment, expand cohort sizes, and integrate multi-omics approaches to refine prognostic and therapeutic applications.
Analisa kepuasan pasien rawat jalan jaminan BPJS terhadap pelayanan kefarmasian di instalasi farmasi Rumah Sakit Sumber Waras Jakarta Barat Tjahyanto, Teddy; Saryatmo, Mohammad Agung
Jurnal Manajemen Bisnis dan Kewirausahaan Vol 9 No 3 (2025): Jurnal Manajemen Bisnis dan Kewirausahaan
Publisher : Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmbk.v9i3.34344

Abstract

Service quality becomes the main indicator affecting outpatient satisfaction. Aspects such as the physical quality of the hospital, drug quality standards, staff attention to patients, a straightforward administration system to competent health workers in their fields are some factors affecting patient satisfaction. The many complaints about the poor facilities provided and the long waiting times at Sumber Waras Hospital raise questions about how much influence service quality has on patient satisfaction. Therefore, a study was conducted to evaluate the influence of tangible, reliability, responsiveness, assurance and empathy dimensions on patient satisfaction. This study was conducted using the SEM-PLS. Data on this research collected through questionnaires based on a Likert scale with 1-5 representing respondents' agreement on each statement from each dimension. Furthermore, the questionnaire data was analyzed using SmartPLS3 software. The results of the study showed that the tangible, reliability, responsiveness and assurance dimensions had a significant effect on outpatient satisfaction. Meanwhile, the empathy dimension was observed to have no effect on patient satisfaction. From these results, it give an overview that patients at Sumber Waras Hospital prioritize the physical quality of the hospital, drug quality standards, a straightforward administration system, and competent health workers in their fields compared to staff attention to patients. The results of this study are expected to provide an overview of the quality of service at Sumber Waras Hospital. Kualitas pelayanan rumah sakit menjadi salah satu indikator kunci yang mempengaruhi kepuasan dari pasien rawat jalan. Aspek seperti kualitas fisik rumah sakit, standar mutu obat, perhatian staf kepada pasien, sistem administrasi yang tidak berbelit hingga petugas kesehatan yang kompeten pada bidangnya menjadi acuan terhadap kepuasan pasien. Banyaknya pengaduan tentang buruknya fasilitas yang diberikan serta lamanya waktu tunggu pada rumah sakit sumber waras memberikan pertanyaan seberapa besar pengaruh kualitas pelayanan terhadap kepuasan pasien. Oleh itu dilakukan penelitian untuk menguji pengaruh dimensi tangible, reliability, resposiveness, assurance dan empathy terhadap kepuasan pasien. Penelitian ini dilakukan dengan metode SEM-PLS dengan sumber data primer diambil dari jawaban kuesioner. Kuesioner yang digunakan dalam penelitian ini disusun berdasarkan skala likert dengan angka 1-5 yang merepresentasikan kesetujuan dari responden terhadap pertanyaan dari masing-masing dimensi. Selanjutnya data kuesioner dianalisa dengan perangkat lunak SmartPLS3. Dari penelitian didapatkan hasil dimana dimensi tangible, reliability, responsiveness dan assurance berpengaruh signifikan terhadap kepuasan pasien rawat jalan. Sementara itu dimensi empathy teramati tidak berpengaruh terhadap kepuasan pasien. Dari hasil ini terlihat bahwa pasien rumah sakit sumber waras lebih mementingkan kualitas fisik rumah sakit, standar mutu obat, sistem administrasi yang tidak berbelit hingga petugas kesehatan yang kompeten pada bidangnya dibandingkan dengan perhatian staf kepada pasien. Hasil penelitian ini diharapkan bisa memberikan gambaran kualitas pelayanan pada rumah sakit Sumber Waras.
Co-Authors Afif Ramadhan, Afif Alexander, Devin Angelica Novian, Gabriel Angellina Mulyadi, Eunike Didi Suryadi Eldy, Eldy Ellyamurti, Devanti Octavia Erwin, Ferdinand Felicia, Clarissa Heni Pujiastuti Larissa, Olivia Liora, Kevin Mayung, Claraiva Negara, Puspa Niaga, Karmenia Jessica Kurnia Nugroho, Fajar Prianto Oktavia, Anissya Rima Putra, Ananda Ramli Rianto, Louis Riskyana, Claudya Dwie Saryatmo, Mohammad Agung Suherman, Levita Dyah Kartika Sungkarto, Kenny Suryakanto, Milani Syarifah, Anisa Ulaya Tarigan, Tiara Namora Velma Herwanto Wijaya, Jeremiah Hilkiah Wiracakra, I Gusti Lanang Krisna Wiyono, Putri Dhiya Prameswari Yohanes, Guntur