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Maharani, Dhavina
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Health Professions Public Health Veterinary

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Evaluation of the Use of Antidiarrheal Drugs and Antibiotics in Inpatients at a Number of Hospitals Maharani, Dhavina; Hilmi, Indah Laily
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

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Abstract

Diarrhea is one of the health problems that are often faced by the community, usually caused by microorganisms such as bacteria, parasites, viruses, and protozoa that are transmitted between individuals through the fecal-oral route. The handling of diarrhea recommended by WHO is referred to as cross-management of diarrhea by providing rehydration, zinc supplements, nutrition, antibiotics and education for parents or caregivers. The research method used is to collect several articles from the latest published journals which were then reviewed and reviewed. The purpose of this review article is to know the evaluation of the use of antidiarrheal drugs and antibiotics based on categories of inpatients in several hospitals. The results show that the prevalence of diarrhea in patients is dominated by men with an age range of 0-14 in children and the elderly over 50 years. Diarrhea can be managed by giving rehydration, zinc supplements, nutritional therapy, antibiotics, antidiarrheals, antipyretics, analgesics and antiemetics to reduce the symptoms and duration of diarrhea. Diarrhea therapy at several health facilities has shown quite good results through evaluation of drug administration through several observations including the right indication, right patient, right drug, right dose, right administration and right time of administration.
Study Of Molecular Docking On Compounds With Potential As Anti-Inflammatory Ravelliani, Andien; Nisrina, Hasna'; Sari, Lala Komala; Marisah, Marisah; Agustin, Annastya Eka; Maharani, Dhavina; Utami, Marsah Rahmawati; Nurfadhila, Lina
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.665 KB)

Abstract

Inflammation is a protective response caused by damage to certain tissues. Anti-inflammatory is a substance or drug used to treat redness, increased body temperature, swelling, pain and loss of function of an organ. Steroid and non-steroidal anti-inflammatory drugs have many side effects, so studies are needed to develop new drugs to minimize side effects and improve therapeutic effects. The method used is literature review from journals and articles obtained from Google Scholar in 15 journals. The purpose of the literature review is to find out the study of the development of new drugs from several compounds that have potential as anti-inflammatories. Secondary metabolites that have potential as anti-inflammatory include essential oils, flavonoids, alkaloids, terpenoids, and anthocyanins. Secondary metabolites will interact with the cyclooxygenase (COX) enzyme which is the main mediator of inflammation. The results obtained from the 15 compounds contain these secondary metabolites so they have the potential as anti-inflammatory.
Co-Authors Agustin, Annastya Eka Fauziah, Anisa Indah Laily Hilmi Marisah, Marisah Marsah Rahmawati Utami Mukti, Galih Ibnu Nisrina, Hasna' Nurfadhila, Lina Nurfadhilah, Lina Ravelliani, Andien Sari, Lala Komala Tyasna, Putri Setya Zakiyah, Wildani