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Uji Aktivitas Sitotoksik Ekstrak Kulit Bawang Putih (Allium satovum L.) Dengan Metode BSLT (Brine Shrimp Lethality Test) Hesti Marliza; Yunisa Friscia Yusri; Henny Rachdiati
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 1 (2022): Januari: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v1i1.2824

Abstract

Garlic (Allium sativum L.) stores many benefits as traditional medicines that have long been known to overcome and prevent various diseases such as antimicrobials, anticancers, antioxidants and antidiabetics but the potential of garlic skin research has not been found as an anticancer by using the BSLT (Brine shrimp lethality test) method as a preliminary test. This study was conducted to find out the toxicity of garlic skin extract (Allium sativum L.) using the BSLT extract method made by maceration using methanol solvent. Toxicity tests are performed using the larvae of the 48-hour-old Artemia saline Leach shrimp. The toxic effects of the extract are identified with a percentage of shrimp larva mortality using probit analysis (LC50). The results showed that garlic skin extract contains alkaloid compounds, flavonoids, phenolics, and triterpenoids. Toxic extracts are characterized by LC50 values <1000μg/ml. and the results of the toxicity test of garlic skin extract with methanol solvent have an LC50 value of 44.18μg / ml with toxic category. Keywords: Garlic Tuber skin ((Allium sativum L.), Brine Shrimp Lethality Test, The results showed that garlic skin extract contains alkaloid compounds, flavonoids, phenolics, and triterpenoids. Toxic extracts are characterized by LC50 values <1000μg/ml. and the results of the toxicity test of garlic skin extract with methanol solvent have an LC50 value of 44.18μg / ml with toxic category.
Pengabdian Kepada Masyarakat Melalui Peningkatan Kualitas Hidup Lansia Melalui Penerapan Pola Hidup Sehat Di Batam Aprilya Sri Rachmayanti; Suhaera Suhaera; Ghalib Syukrillah Syahputra; Henny Rachdiati
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 1 No. 1 (2023): Februari : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v1i1.220

Abstract

The aging process is a natural phenomenon experienced by every individual, characterized by physical and mental changes that affect the body's functions and capabilities. The speed of the aging process can vary between individuals due to the influence of hormones and other factors. Elderly is often thought of as a disease, whereas aging is actually a natural process of decreasing the body's resistance to external and internal stimuli. During aging, the elderly experience physical, mental and psychological changes. Efforts to improve the health of older adults with chronic diseases are made through the adoption of a healthy lifestyle. This includes regular exercise programs, a healthy diet by limiting salt, fat, and cholesterol intake, quitting smoking, avoiding alcoholic beverages and caffeine, managing emotional stress, and undergoing regular monthly health check-ups. With age, older adults are at risk of various diseases, decreased body functions, imbalances, and the risk of falls. These challenges often conflict with older adults' desire to remain independent and active. The mismatch between expectations and conditions can even lead to depression. Therefore, there is a need for special attention to the health and well-being of the elderly with chronic diseases to maintain their quality of life.