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All Journal Infotekmesin Journal of Experimental and Clinical Pharmacy (JECP)
Ismawati, Nurul
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Electrical & Electronics Engineering Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health

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Aktivitas Antibakteri Ekstrak Buah Pare (Momordica charantia L.) Terhadap Bakteri Vibrio cholerae dan Bacillus cereus Ismawati, Nurul; Salasa, Alfrida Monica; Daswi, Dwi Rachmawaty
Journal of Experimental and Clinical Pharmacy (JECP) Vol 3, No 1 (2023): February 2023
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v3i1.611

Abstract

Buah pare (Momordica charantia L.)  merupakan tanaman yang memiliki bau khas yang dimanfaatkan oleh masyarakat sebagai sayuran dan untuk pengobatan tradisional seperti batuk berdahak dan disentri. Buah pare memiliki kandungan senyawa alkaloid, flavonoid, saponin, tannin, dan triterpenoid yang dapat memiliki aktivitas sebagai antibakteri. Penelitian ini bertujuan untuk menentukan aktivitas antibakteri berdasarkan diameter zona hambat ekstrak buah pare terhadap Vibrio cholerae dan Bacillus cereus. Buah pare dikeringkan lalu di maserasi dengan pelarut etanol 96% dilanjutkan uji skrinning fitokimia dan uji aktivitas antibakteri dengan metode disc diffusion konsentrasi ekstrak 2%, 4%, 8% kontrol positif menggunakan antibiotik kloramfenikol dan kontrol negatif DMSO. Hasil penelitian menunjukkan ekstrak buah pare memiliki aktivitas terhadap bakteri Vibrio cholerae dan Bacillus cereus dan konsentrasi yang memiliki zona hambat terbesar adalah konsentrasi 8%.Bitter gourd fruit (Momordica charantia L.) is a plant that has a distinctive smell and is used by the community as a vegetable and for traditional medicine such as cough with phlegm and dysentery. Bitter gourd contains alkaloids, flavonoids, saponins, tannins, and triterpenoids that have antibacterial activity. This study aims to determine the antibacterial activity based on the diameter of the inhibition zone of bitter melon extract against Vibrio cholerae and Bacillus cereus. Bitter gourd fruit was dried and then macerated with 96% ethanol as a solvent, followed by phytochemical screening tests and antibacterial activity tests using the disc diffusion method with extract concentrations of 2%, 4%, and 8% as positive controls using chloramphenicol antibiotics and DMSO as a negative control. The results showed that bitter melon extract had activity against the bacteria Vibrio cholerae and Bacillus cereus, and the concentration that had the largest inhibition zone was 8%.
Pengembangan Aplikasi Telemedicine Carevul Sebagai Optimalisasi Pelayanan Kesehatan Berbasis Cloud Ismawati, Nurul; Rosi Subhiyakto, Egia
Infotekmesin Vol 15 No 1 (2024): Infotekmesin: Januari, 2024
Publisher : P3M Politeknik Negeri Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35970/infotekmesin.v15i1.2150

Abstract

Telemedicine is a healthcare service that utilizes information and communication technology to offer virtual medical services, eliminating the need for the physical presence of patients and medical professionals in a single location. The development of telemedicine enhances the accessibility of healthcare services, helps overcome constraints of time and resources, and can reduce healthcare service costs. Consultation services at UPT Puskesmas Tirto Kota Pekalongan are still manual and have not fully optimized the use of technology. The process of meeting the needs for consultations with doctors requires a direct visit to the health center, resulting in a significant use of time and resources. Therefore, a website-based system is needed as a platform to provide easy and practical online telemedicine consultation services. This research employs the prototyping development method, allowing users to participate by evaluating and providing feedback during the development process. System testing using Blackbox and User Acceptance Test (UAT) shows a user satisfaction percentage of 89.6%, indicating that the majority of users strongly agree with the developed website. The development of this website is expected to facilitate users and medical personnel in conducting online consultations anywhere and anytime without the need to visit the health center.
Co-Authors Daswi, Dwi Rachmawaty Rosi Subhiyakto, Egia Salasa, Alfrida Monica