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Trends in publication and collaboration of health-themed systematic reviews before and during the COVID-19 pandemic: A bibliometric study Chiari, Williams; Amirah, Shakira; Lemu, Yohannes K.; Subbaram, Kannan; Edwards, Robert J.; Kretchy, James-Paul; Vento, Sandro; Khader, Yousef; Rademaker, Marius
Narra X Vol. 2 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v2i1.106

The presence of global threats such as coronavirus disease 2019 (COVID-19) pandemic could potentially affect the research landscape, particularly that of systematic reviews. The aim of this study was to examine disparities between countries and the role of funding availability in the publication of health-themed systematic reviews. Metadata of published literature was collected from the Scopus database as of June 30, 2023. The dataset was divided into ‘pre-COVID-19 (2017–2019)’ and ‘during COVID-19 (2020–2022)’ by utilizing filter feature of the Scopus search engine. Network visualization of co-authorship was carried out on VoSviewer to identify collaborative patterns between countries. Our results suggest that most of the systematic reviews were published by authors from the United States of America (USA), both in pre-COVID-19 (n=29,463; Total link strength, TLS=32,832) and during COVID-19 (n=35,520; TLS=45,616). During COVID-19, the trend was not much different with the USA (14.6%), the UK (8.8%), and Australia (5%) in the top position among high-income countries. China (12.3%) and Iran (2.4%) topped the upper-middle-income and low-income countries groups. Publications by those who were from low-income countries were in a concerning low number; Ethiopia ranked first in this group only occupied 0.4% of the total publications (n=1,047). Furthermore, the number of publications was proportional to the number of funded studies (as observed in the top countries). However, during COVID-19 pandemic, the proportionality between funded publications and total publications was observed less. Taken altogether, our findings stress the importance of capacity building and providing more funds for on-desk research to close the disparity among countries.

Fabrication and characterization of SiO2-embedded castor oil-based membrane (Ricinus communis L) for aqueous Fe adsorption Nisah, Khairun; Khairi, Miratul; Sukandar , Redha; Nuzlia, Cut; Nasution, Reni S.; Ilhami, Syarifa; Chiari, Williams
Narra X Vol. 2 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v2i2.158

Castor seed oil (Ricinus communis L) can be utilized for the manufacturing of membranes reacted with toluene diisocyanate (TDI). The aim of this study was to examine the effect and membrane characteristics of castor seed oil with a combination of silica used as an adsorbent, with a combination of silica (SiO2) 0.5 mg, 1 mg, 1.5 mg, and 2 mg. The initial analysis of the membrane was carried out with a swelling test of 1.5 mg of silica variation to obtain the most ideal result of 200%. The best chemical resistance characterization occurred at a variation of 1.5 mg of silica. Further characterization, particularly the FTIR test, thermal test, mechanical test, and SEM test, showed that there were Si-O groups and amine groups (NH2), and on the membrane there were groups OH, C=O, and NH. The thermal characterization of the silica membrane (1.5 mg) gave the greatest residue concentration, measuring 3.2%. In mechanical terms, the silica membrane has a higher elongation value than the membrane. In SEM characterization, the silica membrane has holes and is solid. This study indicated that the highest drop in Fe metal occurred at an immersion period of 6 hours with a combination of silica with a flux value of 9.25 L/m2 hour and a rejection value of 0.098%.

Chemometric-empowered spectroscopic techniques in pharmaceutical fields: A bibliometric analysis and updated review Zulkifli, Baidillah; Fakri, Fajar; Odigie, Joan; Nnabuife, Loveday; Isitua, Chinwe C.; Chiari, Williams
Narra X Vol. 1 No. 1 (2023): April 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v1i1.80

Undeniable increase in pharmaceutical demand has encouraged researchers to develop analytical techniques to analyze drugs and monitor their effects. Chemometrics enabled simple spectroscopic approaches (such as infrared or UV spectroscopy) to analyze complex samples, including drug formulations, excreted fluids and tissues of living organisms. The aim of this study was to evaluate the research trend of this combinatorial technique utilized for pharmaceutical-related sample analysis using a bibliometric analysis. Bibliometric data of published literature from the Scopus database on March 14, 2023 were retrieved using the keyword combinations of "multivariate", "chemometrics", "pattern recognition", "drug", "pharmaceutical" and "spectroscopy". Network visualization analysis was performed using VOSviewer on the co-occurring keywords and authorships, presenting data such as top cited papers (n=10). The literature review was performed based on the research trend revealed by the clusters that emerged in the network visualization. The analysis revealed that the first paper was published in 1973 (n=1) and a total of 3544 records have been published as of March 14, 2023, comprising original research articles (n=3144, 88.71%) and review articles (n=232, 6.55%). The keyword “chemometrics” with Total Link Strength (TLS) of 826 emerged as the most abundant, followed by “metabolomics” (TLS=388), “Raman spectroscopy” (TLS=280), “metabonomics” (TLS=272), “nuclear magnetic resonance” or “NMR” (TLS=271), and “multivariate analysis” (TLS=254). Network visualization revealed that the research falls into two general categories: (1) drug toxicity and efficacy monitoring and (2) quality control of drug manufacturing. The top cited paper (n=3269) was a review article published in 1999 describing the utility of nuclear magnetic resonance combined with multivariate statistics for metabolite profiling of biological samples. The chemometric-empowered spectroscopy techniques were expected to provide objective measurement during clinical studies and monitoring of therapeutic effects.

Metal oxide/chitosan composite for organic pollutants removal: A comprehensive review with bibliometric analysis Ahmad, Khairunnas; Chiari, Williams
Narra X Vol. 1 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v1i2.91

Organic pollutants are now a global concern because of their rapid increase following the rapid industrial growth. In tackling this problem, researchers have used chitosan that could act as adsorbing material. However, chitosan use in wastewater treatment requires further modification owing to its drawbacks of being susceptible to acidic environment and mechanically weak. Of many modifying approaches, metal-oxide embedment is perceived as promising because not only does it improve the chemical and physical properties of chitosan, but it also adds new features to the material such as being magnetic or photocatalytic. This present review describes the modification of chitosan through metal oxide embedment aiming to its utility in organic waste removal. Firstly, the definition of chitosan and the progress of its application in wastewater treatment are presented. Types of metal oxides, namely photocatalyst and magnetic iron oxide are also discussed. Embedment of metal oxides into chitosan could be done using methods such as sol-gel, high-energy ball milling, and spray-drying, where they affect the chemical and physical properties of the produced metal oxide/chitosan composites. Reported studies suggest a high percentage of organic pollutant removal, up to 100%. In addition to its removal ability, metal oxide/chitosan is also proven to be environmentally friendly and economical.

Trends in publication and collaboration of health-themed systematic reviews before and during the COVID-19 pandemic: A bibliometric study Chiari, Williams; Amirah, Shakira; Lemu, Yohannes K.; Subbaram, Kannan; Edwards, Robert J.; Kretchy, James-Paul; Vento, Sandro; Khader, Yousef; Rademaker, Marius
Narra X Vol. 2 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v2i1.106

The presence of global threats such as coronavirus disease 2019 (COVID-19) pandemic could potentially affect the research landscape, particularly that of systematic reviews. The aim of this study was to examine disparities between countries and the role of funding availability in the publication of health-themed systematic reviews. Metadata of published literature was collected from the Scopus database as of June 30, 2023. The dataset was divided into ‘pre-COVID-19 (2017–2019)’ and ‘during COVID-19 (2020–2022)’ by utilizing filter feature of the Scopus search engine. Network visualization of co-authorship was carried out on VoSviewer to identify collaborative patterns between countries. Our results suggest that most of the systematic reviews were published by authors from the United States of America (USA), both in pre-COVID-19 (n=29,463; Total link strength, TLS=32,832) and during COVID-19 (n=35,520; TLS=45,616). During COVID-19, the trend was not much different with the USA (14.6%), the UK (8.8%), and Australia (5%) in the top position among high-income countries. China (12.3%) and Iran (2.4%) topped the upper-middle-income and low-income countries groups. Publications by those who were from low-income countries were in a concerning low number; Ethiopia ranked first in this group only occupied 0.4% of the total publications (n=1,047). Furthermore, the number of publications was proportional to the number of funded studies (as observed in the top countries). However, during COVID-19 pandemic, the proportionality between funded publications and total publications was observed less. Taken altogether, our findings stress the importance of capacity building and providing more funds for on-desk research to close the disparity among countries.

Fabrication and characterization of SiO2-embedded castor oil-based membrane (Ricinus communis L) for aqueous Fe adsorption Nisah, Khairun; Khairi, Miratul; Sukandar , Redha; Nuzlia, Cut; Nasution, Reni S.; Ilhami, Syarifa; Chiari, Williams
Narra X Vol. 2 No. 2 (2024): August 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narrax.v2i2.158

Castor seed oil (Ricinus communis L) can be utilized for the manufacturing of membranes reacted with toluene diisocyanate (TDI). The aim of this study was to examine the effect and membrane characteristics of castor seed oil with a combination of silica used as an adsorbent, with a combination of silica (SiO2) 0.5 mg, 1 mg, 1.5 mg, and 2 mg. The initial analysis of the membrane was carried out with a swelling test of 1.5 mg of silica variation to obtain the most ideal result of 200%. The best chemical resistance characterization occurred at a variation of 1.5 mg of silica. Further characterization, particularly the FTIR test, thermal test, mechanical test, and SEM test, showed that there were Si-O groups and amine groups (NH2), and on the membrane there were groups OH, C=O, and NH. The thermal characterization of the silica membrane (1.5 mg) gave the greatest residue concentration, measuring 3.2%. In mechanical terms, the silica membrane has a higher elongation value than the membrane. In SEM characterization, the silica membrane has holes and is solid. This study indicated that the highest drop in Fe metal occurred at an immersion period of 6 hours with a combination of silica with a flux value of 9.25 L/m2 hour and a rejection value of 0.098%.

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