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All Journal Biotika: Jurnal Ilmiah Biologi CommIT (Communication & Information Technology) JURNAL PERBENIHAN TANAMAN HUTAN Jurnal Matematika Sains dan Teknologi Chimica et Natura Acta ALCHEMY Jurnal Penelitian Kimia Journal of Science Innovare Komputasi: Jurnal Ilmiah Ilmu Komputer dan Matematika FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Jurnal Ilmu Kefarmasian Indonesia Jurnal Sosial dan Teknologi Gunung Djati Conference Series
Triastinurmiatiningsih, Triastinurmiatiningsih
Program Studi Biologi, FMIPA Universitas Pakuan, Bogor
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Journal : Jurnal Ilmu Kefarmasian Indonesia

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Kajian Mekanisme Estrogenik Kombinasi Ekstrak Kemangi dan Adas melalui Histopat Ovarium dan Uterus Yulianita Yulianita; E. Mulyati Effendi; Triastinurmiatiningsih Triastinurmiatiningsih
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.822

Abstract

Research on the Estrogenic Mechanism Study of the Combination of Basil Herb (Ocimumamericanum) and Fennel Fruit (Foeniculum vulgare) against the background of research results whichshowed that the combination of 70% ethanol extract of basil herbs 0.35g / 200g BB and fennel fruit0.0725g / 200g BB had effi cacy estrogenic because it greatly aff ects the duration of the estrus phase,vascularization and weight of the ovaries and uterus. The aim and target to be achieved from thisresearch is to know the working mechanism of the combination of estrogenic basil and fennel fruitherbs. The parameters observed were histopathological examination of the ovary and uterus. Histopathictest results in the ovary and uterus show the eff ect of treatment on the development of follicles in theovary and uterine wall thickening. So it can be concluded that the mechanism of estrogenic combinationof basil and fennel fruit extracts occurs through the mechanism of genomics, where phytoestrogencompounds in both plants pass through cell membranes and interact with receptors so that they canproduce estrogen-like eff ects.
Co-Authors - Ertina - Ismanto Ade Heri Mulyati, Ade Heri Ade Kusmiati Agustine, Dine Alexander A. S. Gunawan, Alexander A. S. Alexander Agung Santoso Gunawan Ardiani, Weni Ardiansyah , Deden Arfa Ul Hikmah Arie Qur’ania Bilkis, F.G Bina Lohita Sari Bina Lohita Sari D.G. Maelani Dede Giwang Maelani Dewi Sugiharti Dhiandani, Sri Boedi Diana Widiastuti E. Mulyati Effendi Eha Soliha Eka Herlina Erika Candra Ertina, - F.G Bilkis Ghina Athyah Wahid Haris Shobir Hikmah, Arfa Ul Ihat Ismawat Indah Nur Sayyidah Ismanto Ismanto Ismanto, - Jayawinangun,, Roni Jureka Tampubolon Lili Ayu Wulandhari Maelani, D.G. MOERFIAH . Moerfiah Moerfiah Nazar Muhamad Ikhbal Prihastuti Harsani Rahayu, S.Y. Srie Rangga Eka S. P Ratna Uli Damayanti Sianturi Rina Yulianti Rina Yulianti S.Y. Srie Rahayu Sadjarwa, Boedi Shobir, Haris Sinaga, Siska Elisahbet Siti Warnasih Sofian, Yayan Soliha, Eha Sri Wiedarti Sri Wiedarti Sugiharti, Dewi Tampubolon, Jureka Tania Oktavia Herlinda Tri Saptari Haryani Tri Saptari Haryani Tri Saptari Haryani Weni Ardiani Wulandhari, Lili Ayu Yulianita Yulianita Zulkhoir Zulkhoir