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All Journal Medical Journal of Indonesia Jurnal Berkala Epidemiologi CRJIM (Clinical and Research Journal in Internal Medicine)
Abellia, Gaby
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Postoperative Hormonal and Water Balance Disturbances After Non-Functioning Pituitary Macroadenoma Surgery Yudha, Nyoman; Setiabudi, Patan; Abellia, Gaby
Clinical and Research Journal in Internal Medicine Vol. 5 No. 1 (2024): Volume 5 No 1, May 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.01.12

Abstract

Non-functioning pituitary adenomas (NFPAs) are common sellar region tumors. Certain pituitary adenomas are categorized as functional, as they arise from specific cell types that excessively secrete hormones. In contrast, non-functional adenomas do not secrete hormones but can potentially compress the surrounding regions. The lack of hormonal activity in NFPAs often leads to a delayed diagnosis. It becomes clinically significant when the adenoma gets larger and starts causing symptoms. A 52-year-old man presented with visual field impairment since two years ago and throbbing headaches for the last three months. He was found to have pituitary macroadenoma and no hormonal excess was detected. He was diagnosed with non-functioning pituitary macroadenoma, then underwent endonasal endoscopic transsphenoidal hypophysectomy as a surgical procedure in our institute. A surgical procedure to remove pituitary adenomas can lead to high chance of complications in pituitary hormone regulation due to the manipulation of the pituitary gland and its stalk, such as water balance imbalance and hormonal disturbances. Endonasal endoscopic transsphenoidal hypophysectomy as a surgical procedure in treating pituitary macroadenoma has proven effective, resulting in good outcomes. A multidisciplinary approach involving specialists in endocrinology, ophthalmology, and neurosurgery is essential for the comprehensive evaluation of patients with pituitary adenoma.
Association of Sociodemographic Factors in Affecting the Knowledge, Attitude, and Behaviour of Tuberculosis and HIV in Malang: A Community-Based Study in Rural Area Rosandy, Milanitalia; Candradikusuma, Didi; Indiastari, Dewi; Fatma, Endah; Budiarti, Niniek; Sutanto, Heri; Abellia, Gaby
Clinical and Research Journal in Internal Medicine Vol. 5 No. 1 (2024): Volume 5 No 1, May 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.01.07

Abstract

Background: Tuberculosis is the leading cause of death among people with HIV. In Indonesia, the Tuberculosis prevalence in 2021 stood at 969,000 cases with an average of 354 cases per 100,000 people. Nevertheless, tuberculosis is often neglected by many people, whereas in fact, it is a preventable and curable disease. This study aims to assess the knowledge, perception, behaviour, and screening for tuberculosis and their association with sociodemographic factors in a rural area of Malang, Indonesia. Method: A cross-sectional community-based study was conducted. The subjects of this study were adults (≥18 years old) who could comprehend the Indonesian language. We included 462 individuals who were chosen randomly by a multistage stratified sampling technique in rural areas of Malang, Indonesia. A validated questionnaire was asked to be filled in by participants, which were selected randomly using a multistage stratified sampling technique. Collected data were analyzed on SPSS for Windows version 25.0 Results: This study found that most (59.77%) of adults from the study area are still unaware of tuberculosis infection, transmission, prevention, and its risk factors. Only 1.2% were aware of the importance of screening if they had contact with positive tuberculosis patients. Participants in the age groups of 61 to 70 and over 70 years old were 5.5 and 4.0 times more likely to exhibit unsatisfactory behaviour compared to those in the 27 to 30 age group. Conclusion: This study shows that knowledge, perceptions, behaviours and tuberculosis screening toward tuberculosis are still lacking in rural communities in Malang and showed that participant on younger age and higher educational subjects has better knowledge, behaviour, perception and screening towards Tuberculosis and HIV.
THE SOCIODEMOGRAPHICS INFLUENCE IN THE KNOWLEDGE, PERCEPTION, AND BEHAVIOR OF OSTEOPOROSIS IN MALANG: A COMMUNITY-BASED STUDY: Pengaruh Sosiodemografi dengan Tingkat Pengetahuan, Persepsi, dan Perilaku tentang Osteoporosis di Malang: Studi Komunitas Pratama, Mirza Zaka; Suryana, Bagus Putu Putra; Putra, Domy Pradana; Rahmad, Rahmad; Abellia, Gaby
Jurnal Berkala Epidemiologi Vol. 12 No. 2 (2024): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V12I22024.162-172

Abstract

Background: Osteoporosis is a major global health issue that results in disability and high medical expenses. It can significantly impact both individuals and their caregivers, leading to pain, limitations in daily activities, and emotional distress. Purpose: This study observed the association of sociodemographic factors in affecting knowledge, perception, and behavior related to osteoporosis in a rural area of Malang, Indonesia. Methods: A cross-sectional study was conducted in a rural area of Malang to assess the knowledge, perception, and behavior of adults (≥18 years old) toward osteoporosis. Participants were asked to fill in a validated questionnaire, which was selected randomly using a multistage stratified sampling technique. Collected data were analyzed on SPSS for Windows version 25.0. Results: The study included 376 randomly selected participants from various rural areas in Malang. The subjects mostly were within the 51-60 age group (34.0%), with female respondents accounting for 73.4% of the sample. On average, participants scored 1.8 (±2.5) for knowledge, 12.0 (±2.1) for perception, and 12.2 (±2.9) for behavior regarding osteoporosis. Both age and education levels showed associations with knowledge and perception, while only age was significantly linked to behavior concerning osteoporosis. Conclusions: Our study revealed a strong association between low educational levels, especially among the elderly, and the lack of knowledge, perceptions, and behavior toward osteoporosis. 
Formulation of mice diet with low cholecalciferol content Sumariyono; Handayani, Dian; Setiati, Siti; Amalialjinan, Nadia; Abellia, Gaby; Anindyanti, Risma Debby; Dienillah, Syifa Sarah; Ernawati; Tanadi, Caroline
Medical Journal of Indonesia Online First
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257859

Abstract

BACKGROUND Vitamin D deficiency has been linked to autoimmune diseases, cancer, and cardiovascular diseases. Although 1 study attempted to elucidate the ingredients required to make this diet, the process remained unclear. Hence, this study aimed to customize a low cholecalciferol diet with good tolerability in mice. METHODS We customized a diet containing a normal cholecalciferol content (1 IU/g diet) and another with a low cholecalciferol content (0.05 IU/g diet). Samples from both diets were sent to an independent laboratory to ensure that the levels of cholecalciferol, phosphorus, and calcium present in the custom diets matched our calculations. 5 mice were fed the customized normal cholecalciferol diet for 1 week to assess tolerability. Tolerability was assessed by measuring the amount of food consumed, weight gained, and the presence of any adverse events. RESULTS Cholecalciferol, phosphorous, and calcium levels in both diets satisfactorily matched our calculations. The diet was well tolerated without any adverse events or mortalities. The mice consumed an adequate amount of food (mean: 5.34 [0.08] g diet/day, 95% confidence interval [CI]: 5.12–5.56; 19.38 kcal, fat: 0.43 g, protein: 0.14 g, carbohydrates: 3.16 g, and cholecalciferol: 0.007 mg) and gained a slight amount of weight by the end of the experiment (mean: 1.86 [0.46] g, 95% CI: 0.58–3.14). CONCLUSIONS This study successfully created 2 custom diets with quantified cholecalciferol contents. This animal model may prove valuable for studies involving vitamin D.
Co-Authors Amalialjinan, Nadia Anindyanti, Risma Debby Dian Handayani Didi Candradikusuma Dienillah, Syifa Sarah Ernawati Fatma, Endah Heri Sutanto Indiastari, Dewi Niniek Budiarti B Pratama, Mirza Zaka Putra, Domy Pradana Rahmad Rahmad Rosandy, Milanitalia Setiabudi, Patan Siti Setiati Sumariyono Suryana, Bagus Putu Putra Tanadi, Caroline Yudha, Nyoman