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All Journal Jurnal Biomedika dan Kesehatan Jurnal Pengabdian Masyarakat Bangsa Jurnal Ilmiah Sultan Agung JUKEJ: Jurnal Kesehatan Jompa Indonesian Journal of Medical and Pharmaceutical Science
Sundawa, Angga Pria
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Journal : Indonesian Journal of Medical and Pharmaceutical Science

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Pengaruh Pemberian Vitamin C Dosis Tinggi Terhadap Kadar Tumor Necrosis Faktor Alfa Pada Aktivitas Fisik Berat: Studi Eksperimental Pada Tikus Galur Wistar Jantan Trisnadi, Reza Adityas; Sundawa, Angga Pria
Indonesian Journal of Medical and Pharmaceutical Science Vol. 1 No. 2 (2022)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v1i2.90

Abstract

ABSTRACT Strenuous physical activity will cause fatigue in athletes so it will be easier to experience infection. Strenuous physical activity will cause fatigue in athletes so it will be easier to experience infection. This condition in its prevention requires exogenous antioxidants such as vitamin C that reduce ros production. Vitamin C acts as a companion factor in several enzymatic reactions in the body and can boost components of the immune system so that it is expected to lower TNF-α levels. This type of research is an experimental laboratory with a post test only control group design approach using animals to try male white rats with malnutrition conditions that meet the criteria of inclusion and exclusion. The study plan was conducted for ± 22 days. The results of this study are expected to develop the use of high-dose vitamin C as an antioxidant to improve immune function or the immune system for the health of the body. Administering vitamin C at doses of 18 mg / ml / day and 36 mg / ml / day can reduce the amount of TNF-α in male rats who were given heavy physical activity.
Co-Authors Adila, Safira Razan Alfarra, Yuzza Alip, Muhammad Nur Ardiansyah, Muhammad Rifqi Atthar, Muhammad Shahid Fristiani, Ariesta Kurniasari Budi Hastuti, Rizkie Woro Hikmah, Annisa Nurul Puspitasari, Maylani Suryaningrum, Eka Yuliana Trisnadi, Reza Adityas Trisnasdi, Reza Adityas Tulus Ariyadi