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All Journal Journal Pharmaceutical Science and Application (JPSA) Pharmascience Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Cahaya Mandalika JOURNAL SCIENTIFIC OF MANDALIKA (JSM) Jurnal Pengabdian kepada Masyarakat Wahana Usada Bali Medical and Wellness Journal
I Putu Riska Ardinata
Farmasi Klinis, Fakultas Ilmu-ilmu Kesehatan Universitas Bali Internasional
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Medfarm: Jurnal Farmasi dan Kesehatan

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OPTIMALISASI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70% DAUN BINAHONG TERHADAP BAKTERI Staphylococcus aureus I Putu Gede Adi Purwa Hita; I Putu Riska Ardinata; Zainal Firdaus Wardhana
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 12 No 1 (2023): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v12i1.174

Abstract

Binahong leaf (Anredera cordifolia (Ten.) Steenis) contains flavonoids, alkaloids, tannins and saponins that function as antibacterial. Although antibacterial activity test of binahong leaves was done before, but not yet obtained optimum results using ethanol 70% as an extraction solvent. This study aims to determine the optimum antibacterial activity and the effect of increasing the concentration of 70% ethanolic extract of binahong leaves on Staphylococcus aureus bacteria. Binahong leaves were extracted by maceration method using ethanol 70% as solvent. The antibacterial activity was measured using the disc diffusion method and the inhibition zone obtained was also analyzed using statistical analysis. The results showed that the extract had good extract characteristics and contained a class of flavonoids, alkaloids, saponins, and tannins. The antibacterial activity of the binahong leaf extract showed a significant p-velue <0.05 from the Kruskal Wallis test with an inhibition zone in the moderate to strong group. Based on the results of this study it was concluded that the extract had good extract characteristics and contained several classes of phytochemical compounds. For antibacterial activity, the optimum concentration of antibacterial activity of 70% ethanolic extract of binahong leaves was obtained at an extract concentration of 80% with an inhibition zone was 12.85 mm and it also performed that the higher the concentration of the extract, the higher the antibacterial activity obtained. Keywords: Phytochemical Screening, Antibacterial Activity, Staphylococcus Aureus, Anredera cordifolia (Ten.) Steenis.
Co-Authors Adriani, Ni Putu Rina Bagus Komang Satriyasa Dewi, DAP Satrya Dhiancinantyan Windydaca Brata Putri Gayatri, Ni Kadek Weni Diah Hita, Putu Gede Adi Purwa I Gusti Ayu Agung Septiari I Ketut Tunas I Putu Gede Adi Purwa Hita I Wayan Sumardika Maharianingsih, NM Maheni, Ni Putu Asri Dewi Manuaba, IA Ratih Wulansari Ni Luh Sasih Ni Putu Aryati Suryaningsih Ni Putu Wintariani Ni Putu Wintariani Putra, IGNA Windra Wartana Putri, Dhiancinantyan Windydaca Brata Putu Yudhistira Budhi Setiawan Rudiartha, I Gusti Lanang Made Setiawan, Putu Yudhistira Budi Suryaningsih, NP Aryati Sutema, IA Manik Partha Widowati, I Gusti Ayu Rai - Zainal Firdaus Wardhana