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AUTOIMMUNE ENCEPHALITIS: DIAGNOSTIC AND TREATMENT APPROACH Hamdani, Ismi Adhanisa; Agustina, Lydia; Sasongko, Hari Andang; Gaharu, Maula Nuruddin; Rachmatullah, Fahmi; Ghufira, Nanda; Stevany, Nabila; Pawestri, Natasya Rahma Dewi; Fatahuddin, Rahaliya Salsabila; Natasya, Natasya
MNJ (Malang Neurology Journal) Vol. 10 No. 2 (2024): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.02.13

Abstract

Autoimmune encephalitis is a type of brain inflammation induced by an inappropriate immune response to a neuronal antigen, resulting in the generation of autoantibodies. Autoimmunity as important cause of encephalitis in recent years has not been much reported in Indonesia. Increased familiarity with autoimmune encephalitis among physician, not only neurologist, is extremely important for early detection. Prompt diagnosis and early immunotherapy leads to better prognosis in this potentially treatable disease, despite a long disease course. Autoimmune encephalitis is characterized by acute-subacute progressive neuropsychiatric symptoms with associated cognitive dysfunction, encephalopathy, psychiatric disorders, movement disorders and seizures, with anti-N-methyl-D-aspartate (NMDA) receptors encephalitis as the most common type. In addition to clinical features, further diagnostic investigations needed are brain magnetic resonance imaging (MRI), electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, and autoantibody testing. Challenges in establishing diagnosis include wide range of clinical symptoms, absence of abnormalities in brain MRI, unspecified EEG findings, negative antibody testing, and limited availability of antibody testing in Indonesia. This literature review discusses the recognition, diagnosis and principle of treatment of autoimmune encephalitis.
The Influence of Work Discipline and Work Environment on Compliance with Patient Safety Procedures among Health Workers at the Beriman Balikpapan Regional Hospital Rachmatullah, Fahmi; Purwadhi, Purwadhi; Suwardhani, Achmad Dheni
Research of Service Administration Health and Sains Healthys Vol 6, No 1 (2025): Research of Service Administration Health and Sains Healthys (Juni)
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/rehat.v6i1.9036

Abstract

Compliance with patient safety procedures is a crucial component in improving the quality of hospital services. This study aims to analyze the influence of work discipline and work environment on healthcare workers’ compliance with patient safety procedures at RSUD Beriman Balikpapan. The research used a quantitative method with a descriptive-verificative approach. Data were collected through questionnaires distributed to 207 healthcare worker respondents and analyzed using multiple linear regression with validity, reliability, normality, multicollinearity, and heteroscedasticity tests. The results showed that work discipline and work environment variables had a simultaneous and significant effect on compliance with patient safety procedures. Partially, work discipline had a significant influence with a greater contribution compared to the work environment. The coefficient of determination indicated that these two variables explained 52.2% of the compliance with patient safety procedures, while the remaining percentage was influenced by other variables not examined in this study, such as work culture, motivation, and workload. These findings suggest that improving discipline and enhancing the work environment can be effective strategies to encourage healthcare workers to comply with patient safety procedures. Other factors beyond this study, such as organizational culture or workload, are also suspected to influence the level of compliance. 
Tetanus Generalisata Rachmatullah, Fahmi; Mulyono, Eddy; Danarko, Ian
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.19917

Abstract

Tetanus generalisata adalah suatu penyakit yang disebabkan oleh bakteri Clostridium tetani dan dapat menyebabkan gejala serius pada sistem saraf. Penelitian ini bertujuan untuk mengevaluasi berbagai aspek tetanus generalisata, termasuk gejala, penularan, faktor risiko, diagnosis, pengobatan, dan pencegahan. Studi ini menyajikan hasil penelitian berdasarkan analisis data medis dan epidemiologi dari sejumlah kasus tetanus generalisata yang terjadi dalam beberapa tahun terakhir. Ditemukan bahwa gejala khas tetanus generalisata melibatkan kekakuan otot, kejang, dan gangguan sistem saraf. Penularan penyakit ini terjadi melalui luka terbuka atau luka sayatan yang terkontaminasi oleh spora C. tetani. Faktor risiko utama yang diidentifikasi dalam penelitian ini termasuk ketidaklengkapan vaksinasi tetanus, perawatan luka yang tidak adekuat, dan kondisi sosial ekonomi yang rendah. Diagnosis tetanus generalisata didasarkan pada gejala klinis dan pemeriksaan laboratorium. Pengobatan melibatkan pemberian antitoksin tetanus, perawatan luka yang baik, serta manajemen gejala dan komplikasi yang mungkin timbul. Pencegahan tetanus generalisata sangat penting melalui vaksinasi rutin dan perawatan luka yang tepat. Upaya edukasi masyarakat tentang pentingnya vaksinasi tetanus dan perawatan luka yang baik perlu ditingkatkan untuk mengurangi risiko penyakit ini. Penelitian lebih lanjut juga diperlukan untuk memahami epidemiologi dan perubahan tren tetanus generalisata dalam populasi yang berbeda. Kesimpulannya, tetanus generalisata tetap menjadi masalah kesehatan masyarakat yang signifikan. Upaya pencegahan dan penanganan yang tepat sangat penting untuk mengurangi angka kejadian dan dampak negatif penyakit ini pada individu dan masyarakat secara keseluruhan.
Pola Terapi Diare Akut pada Balita Di Rumah Sakit Umum Daerah Ciawi Sulawati, Ity; Cornelia, Celine; Feliks, Mikhael; N, Ivy Fu; Simatupang, Lestari; Angelina, Chesia; Christian, David; Rachmatullah, Fahmi
MAHESA : Malahayati Health Student Journal Vol 3, No 9 (2023): Volume 3 Nomor 9 (2023)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v3i9.11047

Abstract

ABSTRACT Acute diarrhea is one of the most common diseases found in Indonesia. The prevalence of acute diarrhea in Indonesia in 2018 reached 37.88%, in most cases, viral in origin. The mortality rate for acute diarrhea was high among children aged <5 years. This study was conducted to examine the therapy pattern of acute diarrhea in toddlers. This study aims to find out whether the pattern of therapy for acute diarrhea in toddlers at the Ciawi Regional General Hospital is in accordance with WHO therapy standards and how the pattern of therapy for acute diarrhea in toddlers at the Ciawi Regional General Hospital. This research is a descriptive and was conducted in the SMF Department of Pediatrics, Ciawi Hospital. Data collection is carried out retrospectively using medical records starting from April 01, 2022 to June 30, 2022. Out of 78 samples, children afflicted with acute diarrhea is predominantly male (65.5%), aged 1-1.5 years (28%), with mild-moderate dehydration (57.7%) requiring hospitalization (61.5%). The most frequently administered pharmacological therapy was zinc (94.9%) followed by probiotics (92.3%), while ORS (15.4%) and antibiotics (12.8%) were given only in selective cases. This study found that the treatment pattern for acute diarrhea in children at RSUD Ciawi was generally in line with guidelines for the management of acute diarrhea according to WHO standards, where only 4 (5.1%) patients were outpatients who missed out zinc prescription. Keywords: Acute Diarrhea, Antibiotics, Probiotics, Toddler, Zinc  ABSTRAK Diare akut adalah salah satu penyakit yang banyak ditemukan di Indonesia. Prevalensi diare akut di Indonesia pada tahun 2018 mencapai 37,88%, sebagian besar disebabkan rotavirus. Angka mortalitas terbesar diare akut ditemukan pada anak usia <5 tahun. Karena itu, penelitian ini dilakukan untuk menelaah kesesuaian pola terapi diare akut pada balita. Penelitian ini bertujuan untuk mengetahui apakah pola terapi diare akut pada balita di Rumah Sakit Umum Daerah Ciawi sudah sesuai dengan standar terapi WHO dan bagaimana pola terapi diare akut pada balita di Rumah Sakit Umum Daerah Ciawi. Penelitian ini bersifat deskriptif dan dilakukan dibagian SMF Ilmu Kesehatan Anak RSUD Ciawi. Pengambilan data dilakukan secara retrospektif menggunakan rekam medis mulai dari 01 April 2022 hingga 30 Juni 2022. Dari 78 sampel, ditemukan penderita diare akut paling banyak berjenis kelamin laki-laki (65,5%), berusia 1-1.5 tahun (28%), dengan derajat dehidrasi ringan-sedang (57,7%) hingga memerlukan rawat inap (61,5%). Terapi farmakologik yang paling banyak diberikan adalah zink (94,9%) lalu diikuti probiotik (92,3%), sedangkan oralit (15,4%) dan antibiotik (12,8%) hanya diberikan pada kasus selektif. Penelitian ini menemukan pola terapi diare akut pada anak di RSUD Ciawi secara umum sesuai dengan pedoman tatalaksana diare akut menurut standar WHO, dimana hanya 4 (5,1%) pasien rawat jalan yang tidak mendapat zink. Kata Kunci: Antibiotik, Balita, Diare akut, Probiotik, Zink