Article Per Year (5 Year)
p-Index From 2020 - 2025
0.751
P-Index
This Author published in this journals
All Journal MNJ (Malang Neurology Journal) PREPOTIF : Jurnal Kesehatan Masyarakat Neurona
Agustina, Lydia
Unknown Affiliation
Health Professions Medicine & Pharmacology Neuroscience Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
AUTOIMMUNE ENCEPHALITIS: DIAGNOSTIC AND TREATMENT APPROACH Hamdani, Ismi Adhanisa; Agustina, Lydia; Sasongko, Hari Andang; Gaharu, Maula Nuruddin; Rachmatullah, Fahmi; Ghufira, Nanda; Stevany, Nabila; Pawestri, Natasya Rahma Dewi; Fatahuddin, Rahaliya Salsabila; Natasya, Natasya
MNJ (Malang Neurology Journal) Vol. 10 No. 2 (2024): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.02.13

Abstract

Autoimmune encephalitis is a type of brain inflammation induced by an inappropriate immune response to a neuronal antigen, resulting in the generation of autoantibodies. Autoimmunity as important cause of encephalitis in recent years has not been much reported in Indonesia. Increased familiarity with autoimmune encephalitis among physician, not only neurologist, is extremely important for early detection. Prompt diagnosis and early immunotherapy leads to better prognosis in this potentially treatable disease, despite a long disease course. Autoimmune encephalitis is characterized by acute-subacute progressive neuropsychiatric symptoms with associated cognitive dysfunction, encephalopathy, psychiatric disorders, movement disorders and seizures, with anti-N-methyl-D-aspartate (NMDA) receptors encephalitis as the most common type. In addition to clinical features, further diagnostic investigations needed are brain magnetic resonance imaging (MRI), electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, and autoantibody testing. Challenges in establishing diagnosis include wide range of clinical symptoms, absence of abnormalities in brain MRI, unspecified EEG findings, negative antibody testing, and limited availability of antibody testing in Indonesia. This literature review discusses the recognition, diagnosis and principle of treatment of autoimmune encephalitis.
EFEKTIVITAS TOKSIN BOTULINUM TIPE A TERHADAP SKALA SPASME, SKALA DEPRESI DAN KUALITAS HIDUP PASIEN HEMIFASIAL SPASME DI RSUD CIAWI Cornelia, Celine; Hamdani, Ismi Adhanisa; Gaharu, Maula N.; Agustina, Lydia
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 4 (2024): Volume 40, No 4 - September 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i2.560

Abstract

Introduction: Approximately 10/100.000 individuals worldwide experience hemifacial spasm (HFS) with a ratio of women-to-men at 2:1. Around 90% HFS patients face social life challenges, leading to self-isolation and decreased quality of life. Therapy modalities for HFS include oral therapy, botulinum toxin injection and surgery, but the oral therapy response rate is low. Aim: To determine the effectiveness of botulinum toxin type A injection on, spasm scale, depression scale and quality of life of HFS patients Methods: A quasi-experimental study was conducted at Ciawi Regional Hospital in May-December 2023. Data were collected using a total sampling technique, injection of Clostridium botulinum neurotoxin type A and succeeded by a 2-weeks, 1 month and 2 month follow-up. We used modified Jankovic scale, Mini International Neuropsychiatric Interview and HFS-7 criteria for our instruments. Results: 29 patients are included in this research, aged 30-93 years (31% are male and 69% are female). 69% suffered left-sided HFS and 31% right-sided HFS. 44,8% patients had hypertension. After 2 weeks post-injection, 81.8% patients with 2nd degree HFS and 71.4% patients with 1st degree HFS reported significant symptom improvement (p = 0.046 and 0.025). Both patient’s degree reported depression improvement without significant p-value (p = > 0.05) after 2 weeks until 2 month post injection. Increased quality of life (p = 0.001). Discussion: Clostridium botulinum neurotoxin type A injection is an effective treatment modality to improve spasm, depression and quality of life in HFS patients at Ciawi Regional Hospital. Keywords: Botulinum Toxin, Degree of Spasm, Experimental, Hemifacial Spasm, Quality of Life
PENDEKATAN DIAGNOSIS DEMENSIA VASKULAR : LAPORAN KASUS Hong, Vicky; A. Hamdani, Ismi; Agustina, Lydia
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i1.26642

Abstract

Demensia vaskular adalah penurunan kognitif multidomain dengan gangguan aktivitas kehidupan sehari-hari yang diakibatkan oleh penyakit serebrovaskular, baik stroke iskemik maupun stroke hemoragik. Demensia vaskular adalah penyebab demensia yang paling umum kedua setelah demensia Alzheimer pada orang usia lanjut (di atas 65 tahun). Demensia vaskular perlu didiagnosis sedini mungkin. Pada kasus gangguan kognitif, diagnosis dan intervensi dini akan memberikan prognosis yang lebih baik, terutama dalam memperlambat penurunan kognitif, aspek fungsional, dan kualitas hidup. Pendekatan diagnostik untuk demensia vaskular menggunakan kriteria yang ada melalui anamnesis, pemeriksaan fisik, skrining neurokognitif dan pencitraan. Alat diagnostik untuk skrining demensia vaskular termasuk The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), Penilaian Kognitif Montreal (MoCA), Pemeriksaan Status Mental Mini (MMSE), dll. Simpulan laporan kasus ini ialah penggunaan kriteria diagnostik dan pemeriksaan akan mengarahkan kepada diagnosis yang tepat. Kami menyajikan kasus demensia vaskular pada pasien berusia 74 tahun yang memiliki riwayat stroke iskemik selama 9 tahun. Keluhan utamanya adalah pelupa, tetapi ternyata skrining neurokognitif menunjukkan adanya gangguan kognitif multidomain. Pasien bergantung penuh dalam aktivitas kehidupan sehari-hari. CT scan kepala menunjukkan infark lakunar multipel dan atrofi otak.
LIPOMA INTRAVENTRIKEL DENGAN KADAR TRIGLISERIDA TINGGI SEBAGAI PENYEBAB NYERI KEPALA SEKUNDER : SEBUAH LAPORAN KASUS Maurika, Elisya Shafa Ananda; Adhanisa, Ismi; Mumaiyyizah, Shofiatul; Sasongko, Hari Andang; Gaharu, Maula Nuruddin; Agustina, Lydia; Wati, Djung Lilya
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 3 (2025): DESEMBER 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i3.51990

Abstract

Lipoma intraventrikular merupakan lesi intrakranial jinak yang jarang ditemukan dan umumnya asimtomatik, namun dapat menimbulkan gejala neurologis bila disertai faktor risiko metabolik seperti dislipidemia. Seorang laki-laki berusia 35 tahun datang dengan nyeri kepala kronis non-pulsatil dengan NRS 6 sejak tiga bulan, tidak membaik dengan terapi konservatif, serta memiliki riwayat konsumsi makanan tinggi lemak dan keluarga dengan dislipidemia. Tekanan darah 160/100 mmHg, pemeriksaan fisik umum dan status neurologi dalam batas normal, dan pemeriksaan laboratorium menunjukkan hipertrigliseridemia berat (2410 mg/dL). Berdasarkan panduan ICHD-3, pasien memenuhi kriteria chronic tension-type headache, serta terdapat sefalgia sekunder terkait hipertensi dan hipertrigliseridemia, disertai lipoma intraventrikular. Pemeriksaan MRI kepala memperlihatkan lesi berdensitas lemak konsisten dengan lipoma intraventrikular pada ventrikel lateralis kanan (8,2 × 6,2 mm) dan ventrikel ketiga (8,3 × 16,6 mm). Pasien diberikan fenofibrate 600 mg dua kali sehari dan terapi simptomatik berupa parasetamol 1000 mg dua kali sehari eperisone 50 mg dua kali sehari. Didapatkan perbaikan klinis nyeri kepala menjadi NRS 2, tekanan darah 120/80, disertai penurunan kadar trigliserida menjadi 110 mg/dL dicapai setelah terapi.
Co-Authors A. Hamdani, Ismi Adhanisa, Ismi Cornelia, Celine Fatahuddin, Rahaliya Salsabila Gaharu, Maula N. Gaharu, Maula Nuruddin Ghufira, Nanda Hamdani, Ismi Adhanisa Hong, Vicky Maurika, Elisya Shafa Ananda Mumaiyyizah, Shofiatul Natasya Natasya Pawestri, Natasya Rahma Dewi Rachmatullah, Fahmi Sasongko, Hari Andang Stevany, Nabila Wati, Djung Lilya