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All Journal MNJ (Malang Neurology Journal) PREPOTIF : Jurnal Kesehatan Masyarakat
Sasongko, Hari Andang
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Neuroscience Public Health

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AUTOIMMUNE ENCEPHALITIS: DIAGNOSTIC AND TREATMENT APPROACH Hamdani, Ismi Adhanisa; Agustina, Lydia; Sasongko, Hari Andang; Gaharu, Maula Nuruddin; Rachmatullah, Fahmi; Ghufira, Nanda; Stevany, Nabila; Pawestri, Natasya Rahma Dewi; Fatahuddin, Rahaliya Salsabila; Natasya, Natasya
MNJ (Malang Neurology Journal) Vol. 10 No. 2 (2024): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.02.13

Abstract

Autoimmune encephalitis is a type of brain inflammation induced by an inappropriate immune response to a neuronal antigen, resulting in the generation of autoantibodies. Autoimmunity as important cause of encephalitis in recent years has not been much reported in Indonesia. Increased familiarity with autoimmune encephalitis among physician, not only neurologist, is extremely important for early detection. Prompt diagnosis and early immunotherapy leads to better prognosis in this potentially treatable disease, despite a long disease course. Autoimmune encephalitis is characterized by acute-subacute progressive neuropsychiatric symptoms with associated cognitive dysfunction, encephalopathy, psychiatric disorders, movement disorders and seizures, with anti-N-methyl-D-aspartate (NMDA) receptors encephalitis as the most common type. In addition to clinical features, further diagnostic investigations needed are brain magnetic resonance imaging (MRI), electroencephalography (EEG), cerebrospinal fluid (CSF) analysis, and autoantibody testing. Challenges in establishing diagnosis include wide range of clinical symptoms, absence of abnormalities in brain MRI, unspecified EEG findings, negative antibody testing, and limited availability of antibody testing in Indonesia. This literature review discusses the recognition, diagnosis and principle of treatment of autoimmune encephalitis.
LIPOMA INTRAVENTRIKEL DENGAN KADAR TRIGLISERIDA TINGGI SEBAGAI PENYEBAB NYERI KEPALA SEKUNDER : SEBUAH LAPORAN KASUS Maurika, Elisya Shafa Ananda; Adhanisa, Ismi; Mumaiyyizah, Shofiatul; Sasongko, Hari Andang; Gaharu, Maula Nuruddin; Agustina, Lydia; Wati, Djung Lilya
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 3 (2025): DESEMBER 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i3.51990

Abstract

Lipoma intraventrikular merupakan lesi intrakranial jinak yang jarang ditemukan dan umumnya asimtomatik, namun dapat menimbulkan gejala neurologis bila disertai faktor risiko metabolik seperti dislipidemia. Seorang laki-laki berusia 35 tahun datang dengan nyeri kepala kronis non-pulsatil dengan NRS 6 sejak tiga bulan, tidak membaik dengan terapi konservatif, serta memiliki riwayat konsumsi makanan tinggi lemak dan keluarga dengan dislipidemia. Tekanan darah 160/100 mmHg, pemeriksaan fisik umum dan status neurologi dalam batas normal, dan pemeriksaan laboratorium menunjukkan hipertrigliseridemia berat (2410 mg/dL). Berdasarkan panduan ICHD-3, pasien memenuhi kriteria chronic tension-type headache, serta terdapat sefalgia sekunder terkait hipertensi dan hipertrigliseridemia, disertai lipoma intraventrikular. Pemeriksaan MRI kepala memperlihatkan lesi berdensitas lemak konsisten dengan lipoma intraventrikular pada ventrikel lateralis kanan (8,2 × 6,2 mm) dan ventrikel ketiga (8,3 × 16,6 mm). Pasien diberikan fenofibrate 600 mg dua kali sehari dan terapi simptomatik berupa parasetamol 1000 mg dua kali sehari eperisone 50 mg dua kali sehari. Didapatkan perbaikan klinis nyeri kepala menjadi NRS 2, tekanan darah 120/80, disertai penurunan kadar trigliserida menjadi 110 mg/dL dicapai setelah terapi.
Co-Authors Adhanisa, Ismi Agustina, Lydia Fatahuddin, Rahaliya Salsabila Gaharu, Maula Nuruddin Ghufira, Nanda Hamdani, Ismi Adhanisa Maurika, Elisya Shafa Ananda Mumaiyyizah, Shofiatul Natasya Natasya Pawestri, Natasya Rahma Dewi Rachmatullah, Fahmi Stevany, Nabila Wati, Djung Lilya