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Influence of chitosan addition on the properties and characteristics of acrylic acid-chitosan based superabsorbent prepared through gamma irradiation technique and its application for urea loading Jayanudin, Jayanudin; Lestari, Retno Sulistyo D.; Barleany, Dhena Ria; Pitaloka, Alia Badra; Yulvianti, Meri; Demustila, Harly; Yulianto, Amin; Anggoro, Dendy Vito; Ruhiatna, Adam
Jurnal Teknika Vol 19, No 2 (2023): AVAILABLE ONLINE IN NOVEMBER 2023
Publisher : Faculty of Engineering, Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36055/tjst.v19i2.20842

Abstract

Superabsorbent can be used as a carrier for urea-fertilizer which can release urea slowly and can be used as a dry soil moisturizer. The main goal of the current study was to investigate the influence of adding chitosan grafted onto acrylic acid as a superabsorbent base material on the properties and characteristics of the resulting superabsorbents. The method used to prepare the superabsorbent was the gamma irradiation technique. Acrylic acid was neutralized by adding KOH, and then chitosan was added. The mixture was put in a plastic container, followed by irradiation with gamma rays. The formed superabsorbent was washed and dried in an oven, then the dry superabsorbent was analyzed for its properties and characteristics. The results showed that superabsorbent properties such as swelling ratio (from 49.38 g/g to 49.38 g/g), water retention (0.43%-0.89% after 7 days), and urea loading (86.75% to 96.4%) were affected by the amount of chitosan added. However, adding too much chitosan can reduce the superabsorbent properties. The characterization of the superabsorbent revealed a smooth surface with a porous structure, and FTIR analysis showed that chitosan was grafted onto acrylic acid.   
Diffusion and Relaxation Kinetics of Chitosan-graft-poly (Acrylic Acid) Hydrogels: A Theoretical and Experimental Study Jayanudin, Jayanudin; Lestari, Retno S. D.; Barleany, Dhena Ria; Pitaloka, Alia Badra; Yulvianti, Meri; Prasetyo, Dimas
World Chemical Engineering Journal VOLUME 8 NO. 2 DECEMBER 2024
Publisher : Chemical Engineering Department, Engineering Faculty, Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/wcej.v8i2.29920

Abstract

Hydrogels, as three-dimensional polymer networks, are extensively utilized due to their ability to absorb significant amounts of water while remaining insoluble. Chitosan-grafted poly(acrylic acid) hydrogels, in particular, combine high water absorption with improved mechanical properties, making them ideal for applications in agriculture and drug delivery. This study investigates the swelling kinetics of chitosan-graft-poly(acrylic acid) hydrogels synthesized with varying concentrations of the crosslinker N,N'-methylenebisacrylamide (MBA). The objective is to establish the relationship between crosslinker concentration and hydrogel performance by evaluating their swelling behavior using kinetic models. The hydrogels were prepared via free-radical polymerization, with MBA concentrations of 0.015 g (Hgel 1), 0.05 g (Hgel 2), and 0.1 g (Hgel 3). The research results indicate that swelling increases as the MBA concentration decreases. This was attributed to the lower crosslinking density, which reduces the entanglement of polymer chains. Hgel 1 displayed the greatest swelling ratio 171.71 g/g, while Hgel 2 150.21 g/g and Hgel 3 144.76 g/g. The research results indicate that the swelling behavior is best described by the diffusion kinetics model, as evidenced by the best fit between the experimental data and calculations, with R² values of 0.996, 0.996, and 0.984 for Hgel 1, Hgel 2, and Hgel 3, respectively. The applicability of pseudo-second order model, in good agreement with the one found for Hgel 2 (R2 = 0.997). These results suggest that diffusion dominates the swelling behaviour and that hydrogel behaviour is sensitive to crosslinker concentration. This work highlights the potential use of chitosan-graft-poly(acrylic acid) hydrogels for sustainable applications in agriculture and biomedicine.
Molecular docking of seagrass extracts: investigating the interaction with lipoate protein ligase from enhalus acoroides Rochmat, Agus; Kamil, Kintan NR; Syawalia, Nabila R; Yulvianti, Meri; Bukhari, Ahmad; Hariri, Ahmad; Suaedah, Suaedah; Ganiadi, Mochamad
Jurnal Teknika Vol 20, No 2 (2024): Available Online in November 2024
Publisher : Faculty of Engineering, Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/tjst.v20i2.30833

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and has become a serious global health issue due to increasing antibiotic resistance. Genetic variations in this bacterium enable the emergence of drug-resistant strains, necessitating the search for more effective alternative therapies. This study evaluates the potential of Enhalus acoroides metabolites as inhibitors of the Lipoate Protein Ligase (LipB) enzyme, which plays a crucial role in the fatty acid synthesis of M. tuberculosis. The research was conducted through in silico analysis, including Lipinski's Rule of Five screening, ADMET pharmacokinetic modeling, compound identification using GC-MS, and molecular docking using PyRx, with interaction analysis performed via Biovia Studio. Three tested compounds—Lanosterol, N,N'-1,4-phenylenebis Benzamide, and Astragalin—exhibited significant binding affinity to the 1W66 receptor, with binding energies of -7.5 kcal/mol, -6.8 kcal/mol, and -7.8 kcal/mol, respectively. These values surpass those of the positive controls, Rifampicin (-7.0 kcal/mol) and Streptomycin (-6.5 kcal/mol), indicating the potential of these compounds as new anti-TB drug candidates. This study confirms that Enhalus acoroides metabolites have therapeutic potential in TB treatment, particularly in addressing antibiotic resistance. Further in vitro and in vivo studies are required to validate their pharmacological efficacy.TRANSLATE with x EnglishArabicHebrewPolishBulgarianHindiPortugueseCatalanHmong DawRomanianChinese SimplifiedHungarianRussianChinese TraditionalIndonesianSlovakCzechItalianSlovenianDanishJapaneseSpanishDutchKlingonSwedishEnglishKoreanThaiEstonianLatvianTurkishFinnishLithuanianUkrainianFrenchMalayUrduGermanMalteseVietnameseGreekNorwegianWelshHaitian CreolePersian //  TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster PortalBack//
OPTIMASI KONSENTRASI POLIETILEN GLIKOL UNTUK KUAT TARIK, ELONGASI, DAN BIODEGRADASI DALAM TANAH PADA EDIBLE FILM SELULOSA ASETAT Rahmayetty, Rahmayetty; Ramadani, Putri Dwi; Astari, Raisa; Nuryoto, Nuryoto; Adiwibowo, Muhammad Triyogo; Yulvianti, Meri; Hendra, Hendra
JURNAL INTEGRASI PROSES Vol 14, No 1 (2025)
Publisher : JURNAL INTEGRASI PROSES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/jip.v14i1.33264

Abstract

Plastik konvensional yang digunakan sebagai kemasan makanan menimbulkan permasalahan serius karena ketahanannya terhadap panas yang rendah, serta potensi migrasi monomer ke dalam bahan yang dikemas. Permasalahan ini mendorong pencarian alternatif pengganti plastik dari sumber terbarukan yang aman bagi kesehatan dan ramah lingkungan. Salah satu polimer alam yang menjanjikan untuk produksi bioplastik adalah selulosa asetat, yang dikenal ramah lingkungan, tidak beracun, bersifat antimikroba, dan biokompatibel. Untuk meningkatkan kekuatan mekanik edible film berbahan selulosa asetat, digunakan polietilen glikol (PEG) sebagai plasticizer. Penelitian ini bertujuan untuk menentukan konsentrasi PEG yang optimal dalam menghasilkan edible film dengan kekuatan terbaik dari segi kuat tarik, elongasi, dan biodegradasi tanah. Metode yang digunakan yaitu melarutkan 3 gram selulosa asetat ke dalam 30 mL aseton hingga larut sempurna, kemudian menambahkan PEG dengan variasi konsentrasi (1–5% v/v) dan diaduk hingga homogen. Larutan kemudian dicetak dalam cawan petri dan dikeringkan pada suhu ruang selama 24 jam. Hasil penelitian menunjukkan kuat tarik tertinggi (22,29 MPa, ketebalan 0,13 mm) diperoleh pada penambahan PEG 2%. Nilai elongasi tertinggi (66,8%, ketebalan 0,19 mm) dan tingkat biodegradasi terbaik dengan kehilangan berat 36% pada hari ke-14 diperoleh pada PEG 5%. Konsentrasi PEG optimal berada pada 2% dengan nilai tensile strength paling mendekati standar minimal SNI.