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All Journal Indonesian Journal of Pharmaceutical and Clinical Research Mejuajua Jurnal Indah Sains dan Klinis
Muflihah Fujiko
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Edukasi Pencegahan Penyakit Diabetes Menggunakan Obat Herbal di Lingkungan Pengajian Mesjid Namira Medan Muflihah Fujiko; Muharni Saputri; Ginting, Ernawaty; Fanny Rizki; Tambunan, Pravil Mistriyanto
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 4 No. 1 (2024): Agustus 2024
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v4i1.156

Abstract

Diabetes merupakan salah satu penyakit kronis yang ditandai dengan terjadinya peningkatan gula dalam darah yang dapat menyebabkan kerusakan serius pada jantung, pembuluh darah, mata, ginjal dan saraf. Pengobatan diabetes saat ini banyak dilakukan dengan menggunakan obat-obatan alami dari bahan alam, diantaranya adalah jahe, kulit kayu manis, pare, daun sambung nyawa, daun tapak dara, dan daun mimba. Banyak masyarakat yang belum mengetahui manfaat dari penggunaan bahan alam tersebut sehingga perlu dilakukan edukasi dengan melakukan penyuluhan kepada masyarakat. Metode yang dilakukan adalah melalui presentasi. Hasil kegiatan ini bertujuan meningkatkan pengetahuan masyarakat terkait penggunaan bahan alam sebagai terapi pencegahan penyakit diabetes
Efek Antihiperlipidemia Kombucha Daun Kari (Murraya koenigii (L.) Spreng) pada Tikus Putih Jantan (Rattus norvegicus) yang Diinduksi Dengan High Fat dan PTU Hardyanto Napitupulu,; Muharni Saputri; Salmah Handayani Lubis; Muflihah Fujiko; Ernawaty Ginting
Jurnal Indah Sains dan Klinis Vol 2 No 3 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/7xzsgc35

Abstract

Curry leaves (Murraya koenigii (L.) Spreng) is a plant that is often used in cooking spices that are high in fat because curry leaves contain secondary metabolite compounds such asalkaloids, glycosides, and flavonoids that serve to inhibit the growth of free radicals and lower cholesterol levels. Generally curry leaves are processed traditionally in a simple form, while research will process curry leaves in the form of fermented beverages in the form of kombucha tea. This study aims to explore the process of making curry leaf kombucha tea and know the antihiperlipidemia effect. This research is descriptive and experimental, including material collection, simplisia making, phytochemical screening, fermentation of curry leaf kombucha, evaluation of dosage quality, testing of triglyceride levels in rats with Electrode-Based Biosensor technique. The mice used in this study were 25 and divided into 5 test groups. K1 (negative blank), K2 (Simvastatin), K3 (dose 100 ml), K4 (dose 150 ml), K5 (dose 200 ml) induced using 80% egg yolk and PTU 0.2%. The results showed that the quality evaluation of kombucha tea gave good results to pH 3.08-3.44 and did not experience changes in taste and smell. In the group of 5 doses of 200 ml with kombucha tea administration on the 7th to 15th day, it was shown that cholesterol levels decreased from 253.0 mg/dL to 92.2 ml/dL where these results were close to comparing (simvastatin) from 247.8 mg/dL to 79.2 mg/dL
Formulasi dan Uji Antioksidan Sediaan Krim Ekstrak Etanol Buah Asam Cikala (Etlingera elatior (Jack) R. M. Sm) sebagai Pelembab Kulit Zebua, Nilsya Febrika; Sudewi; Siti Arum Widiyanti; Muflihah Fujiko; Nurul Karimah; Supran Hidayat; Rahma Yulia
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.63

Abstract

Cikala acid fruit is fruit of kecombrang plant (Etlingera elatior) which phenolic compounds including flavonoids and has strong antioxidants activity. Antioxidants are nutrients in the form of vitamins and minerals that function to prevent and repair damaged body tissues. Antioxidant compounds are generally used in cosmetic products. The purpose of this study to determine the antioxidant activity of the ethanolic extract of the cikala fruit was formulated into a moisturizing cream. This research is experimental, covering extract manufacture, phytochemical screening, manufacture and testing of cream preparations as well as testing of antioxidant activity in moisturizing cream. The cream formulation formula was made with a concentration ratio of 1.5%, 2%, 2.5% and blank. Chemical compounds from the ethanolic extract of cikala fruit are alkaloids, saponins, flavonoids and triterpenoids; has a homogeneous cream dosage form with a pH range of 5.7-6.1 after short storage and 12 weeks of storage; and has antioxidant activity with inhibitor concentration value of 19.92 g/mL at concentration 2.5%.
UJI AKTIVITAS ANTIHIPERLIPIDEMIA EKSTRAK ETANOL DAUN ARA SUNGSANG (Asystasia gangetica) TERHADAP KADAR KOLESTEROL PADA MENCIT PUTIH JANTAN (Mus musculus) Muharni Saputri; Muflihah Fujiko; Dasopang, Eva Sartika; Shinta Naswa; Nova Arianti
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 2 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i2.18083

Abstract

Hyperlipidemia can be treated with medication. However, the large side effects cause people to return to herbal medicine. Sungsang fig leaves contain flavonoid, tannin and saponin compounds that can reduce cholesterol levels. The stages of the procedure carried out are making simplisia, followed by cold extraction, namely maceration with ethanol p.a solvent as the solvent of choice. Furthermore, phytochemical screening of sungsang fig leaf extract and simplisia characterization studies were carried out. After that, anti-hyperlipidemia activity was tested in vivo using male white mice to determine the effect of reducing blood cholesterol levels with ethanol extract of sungsang fig leaves. The result of the decrease in cholesterol levels in white male mice from ethanol extract of sungsang fig leaves at a dose of 500 mg/kg BW was 41%. These results are 1.20 times greater than the dose of 125 mg/kg BW and 1.17 times greater than the dose of 250 mg/kg BW. Synergistic compounds to reduce cholesterol levels are flavonoids, tannins and saponins. The decrease in cholesterol levels from ethanol extract of sungsang fig leaves at a dose of 500 mg/kg BW is not significantly different from simvastatin 10 mg.
EDUKASI BAHAYA PENGGUNAAN OBAT TANPA RESEP DAN PENYALAHGUNAAN OBAT DI DESA MARINDAL 1, PATUMBAK DELI SERDANG Tambunan, Pravil Mistryanto; Barus, Bunga Rimta; Muflihah Fujiko; Ginting, Ernawati
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 5 No. 1 (2025): Agustus 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v5i1.260

Abstract

Kegiatan pengabdian masyarakat ini bertujuan memberikan edukasi tentang bahaya penggunaan obat tanpa resep dan penyalahgunaan obat kepada masyarakat Desa Marindal 1, Patumbak Deli Serdang. Metode yang digunakan adalah ceramah interaktif, diskusi kelompok, dan pembagian leaflet edukasi dengan melibatkan 45 peserta yang terdiri dari ibu-ibu PKK, remaja, dan tokoh masyarakat. Evaluasi dilakukan melalui pre-test dan post-test menggunakan 15 soal pilihan ganda. Hasil menunjukkan peningkatan signifikan pengetahuan peserta dengan rata-rata nilai pre-test 58,7 (SD=18,2) meningkat menjadi 82,4 (SD=12,6) pada post-test, menunjukkan peningkatan 23,7 poin (40,4%, p<0,001). Sebanyak 33 peserta (73,3%) mencapai kategori baik-sangat baik (?75) pada post-test dibandingkan hanya 12 peserta (26,7%) pada pre-test. Tingkat kepuasan peserta mencapai 4,7/5,0 dengan 91,1% menyatakan sangat puas. Follow-up setelah 1 bulan menunjukkan 78% peserta telah menerapkan pengetahuan dalam kehidupan sehari-hari dan 82% peserta telah menyosialisasikan informasi kepada keluarga dan tetangga. Kegiatan ini berhasil meningkatkan kesadaran masyarakat tentang pentingnya penggunaan obat yang rasional dan mengurangi risiko penyalahgunaan obat di tingkat komunitas. Dampak jangka panjang yang diharapkan dari kegiatan ini meliputi keberlanjutan kesadaran yang dihasilkan melalui pembentukan kader kesehatan serta rencana tindak lanjut yang melibatkan kerjasama dengan fasilitas kesehatan setempat untuk memberikan konsultasi berkelanjutan dan monitoring praktik penggunaan obat rasional di masyarakat.
Co-Authors Barus, Bunga Rimta Ernawaty Ginting Eva Sartika Dasopang Fanny Rizki Sembiring Ginting, Ernawati Ginting, Ernawaty Hardyanto Napitupulu, Muharni Saputri Nilsya Febrika Zebua, Nilsya Febrika Nova Arianti NURUL KARIMAH Rahma Yulia Salmah Handayani Lubis Shinta Naswa Siti Arum Widiyanti Sudewi Supran Hidayat Tambunan, Pravil Mistriyanto Tambunan, Pravil Mistryanto