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All Journal Jurnal Prima Medika Sains Mejuajua Jurnal Pengabdian Masyarakat Tjut Nyak Dhien JURNAL KIMIA SAINTEK DAN PENDIDIKAN Journal of The Indonesian Society of Integrated Chemistry
Tambunan, Pravil Mistryanto
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Formulation and evaluation of red ginger extract tablet (Zingiber officinale var. rubrum) as lozenges Paramitha, Ratih; Marfitania, Taranipa; Januarti, Ria; Hanief, Said; Tambunan, Pravil Mistryanto
Jurnal Prima Medika Sains Vol. 6 No. 1 (2024): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i1.5256

Abstract

Red ginger (Zingiber officinale var. rubrum) with a high content of phenols (e.g. gingerol, shogaol, etc.) has potential effects against throat inflammation such as cold, sore throat, tonsilitis, etc. This research aims to determine the formulation of lozenge tablets using red ginger extracts. Lozenges tablets are made from dry ginger extract using a wet granulation method prepared by various concentrations of pregelatinized cassava starch 1 % w/v (F0); 2 % w/v (F1) and 5 % w/v (F2) as a binder and HPMC 2 % w/v (F3) as a comparative binder. Red ginger extract was prepared by maceration method using 96% ethanol solvent which is then evaporated using a rotary evaporator to obtain a thick extract. Thick red ginger extract is formulated into lozenges with various formulations F0, F1, F2, and F3. Physical characteristics evaluation of lozenge tablets includes physical appearance, weight uniformity, hardness, and disintegration time. The physical appearance of the tablet is round in shape and bright yellow in color. Based on the evaluation of all the formulas made, F2 has good criteria as a red ginger extract lozenge which has a hardness of 6 kg and disintegration time of 5 minutes 4 seconds.
Penyuluhan Pencegahan Diabetes Melitus Dengan Memanfaatkan Tumbuhan Obat Berkhasiat Kepada Komunitas Sehat Di Stadion Teladan Medan Tambunan, Pravil Mistryanto; Tambunan, Ika Julianti; Sari, Nurmala; Siahaan, Desi Natalia; Lubis, Salmah Handayani
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 2 No 2 (2023): Edisi Juli 2023 - Desember 2023
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v2i2.776

Abstract

Telah dilakukan penyuluhan kepada komunitas sehat di Stadion Teladan Medan terkait pencegahan diabetes melitus dengan mensosialisasikan manfaat penggunaan tumbuhan obat berkhasiat. Penyuluhan dilakukan secara acak dengan mendatangi individu-individu dari komunitas sehat yang sedang beristirahat selepas berolahraga di area Stadion Teladan Medan. Adapun tim yang tergabung atas para dosen dan mahasiswa menawarkan pemeriksaan kadar gula darah gratis dengan menggunakan glucometer digital. Setelah mendapatkan hasilnya, mahasiswa lalu menginterpretasikan hasilnya kepada individu yang diperiksa. Setelah itu, tim memberikan penyuluhan agar konsisten mengimplementasikan gaya hidup sehat serta menyarankan penggunaan tumbuhan obat untuk menjaga kadar gula darah di ambang normal. Evaluasi dilakukan berdasarkan ceklis pemahaman yang diberikan kepada semua individu yang diperiksa gula darahnya. Hasil evaluasi menunjukkan bahwa, setiap individu yang diperiksa pada komunitas Sehat di Stadion Teladan Medan telah memahami materi sosialisasi yang diberikan serta mampu mengolah tanaman obat berkhasiat sebagai ramuan untuk menjaga kesehatan agar bebas dari diabetes.
Testing the Antioxidant Potential of Mango Leaves (Mangifera indica) from Bandar Khalipah Village, Deli Serdang Regency Using the FRAP Method Tambunan, Pravil Mistryanto; Sihotang, Supran Hidayat
Journal of The Indonesian Society of Integrated Chemistry Vol. 16 No. 1 (2024): Journal of The Indonesian Society of Integrated Chemistry
Publisher : Pendidikan Kimia FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jisic.v16i1.34163

Abstract

This study aims to identify and analyze the antioxidant potential of mango leaves (Mangifera indica) sourced from Bandar Khalipah Village, Deli Serdang Regency. Mango leaves are known to contain various secondary metabolites such as flavonoids, tannins, saponins, alkaloids, glycosides, as well as steroids and triterpenoids, which play a crucial role as natural antioxidants. The extraction process was carried out by maceration using 96% ethanol, yielding a thick extract with a rendement of 117%. Phytochemical screening indicated the presence of active compounds in the mango leaf extract. Antioxidant capacity was measured using the FRAP (Ferric Reducing Antioxidant Power) method, resulting in an average value of 151.7 mgAAE/g extract. These results suggest that mango leaves have significant potential as a natural antioxidant source that can be utilized to prevent damage caused by free radicals in the body. This study reinforces the use of mango leaves as a natural alternative for public health.
KARAKTERISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN SERAI (Cymbopogon citratus) DESA BANDAR KHALIPAH TERHADAP MENCIT JANTAN (Mus musculus) Tambunan, Pravil Mistryanto
JURNAL KIMIA SAINTEK DAN PENDIDIKAN Vol. 6 No. 1 (2022): JURNAL KIMIA SAINTEK DAN PENDIDIKAN
Publisher : Program Studi Kimia - Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/kimia.v6i1.2968

Abstract

Research has been carried out to determine the LD50 value and observe the toxic effects of Ethanol Extract of Lemongrass Leaves (EEEL) on male mouse using 64 male mouse which were divided into 4 groups. The control group was given 0.5% CMC-Na suspension while the treatment group was given a single dose of EEEL suspension with doses of 1500, 3500, and 7000 mg/kg BW given on the first day. Observations of toxic symptoms, changes in body weight and number of deaths were carried out for a span of 7-14 days. After observation, the surviving mouses were sacrificed for macropathological and histopathological examination of the liver and kidneys. The determination of the LD50 value was calculated based on the Indonesian Pharmacopoeia Method Edition VI, while the statistical data was tested using Quadratic Nonlinear Regression (QNR) with the SPSS computer program. The simplicia characterization showed positive results on triterpenoid, tannin, flavonoid, and saponin tests, and anthraquinone glycosides and negative results on alkaloid and steroid tests. The results showed that there were toxic symptoms starting in the 3500 and 7000 mg/kg BW dose groups. The statistical results of Quadratic Nonlinear Regression (QNR) also showed no significant difference between each group. In addition, there were no color differences in all groups in the results of organ macropathology. However, liver damage was found on organ macropathological examination at doses of 1500, 3500, and 7000 mg/kg BW. Meanwhile, EEEL doses of 3500 and 7000 mg/kg caused glomerular hypertrophy and dilation of several renal tubules. The LD50 result is 4,965.92 mg/kg BW which indicates that EEEL was categorized as moderate toxic.
Pelatihan Sistem Sertifikasi International Sustainability and Carbon Certification (ISCC) di Industri Oleokimia Pengolahan Bahan Baku Berbasis Kelapa Sawit Tambunan, Pravil Mistryanto; Juniar, Anna; Rajali, Mariany; Saputri, Muharni; Kembaren, Fanny
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 4 No 2 (2025): Edisi Juli 2025 - Desember 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v4i2.1783

Abstract

This community service activity aims to provide training on the International Sustainability and Carbon Certification (ISCC) system to employees of a palm oil-based oleochemical industry company that processes residues and waste from palm oil derivative products. The training utilized a blended learning approach with pre-test and post-test evaluation using 20 multiple-choice questions, involving 30 participants. The results showed a significant improvement in participants' understanding, with average pre-test scores of 62.3 (SD=15.8) increasing to 87.7 (SD=9.4) on post-test, indicating an improvement of 25.4 points (40.7%, p<0.001). Twenty-one participants (70%) achieved excellent category (90-100) on post-test compared to only 6 participants (20%) on pre-test. Participant satisfaction reached 4.6/5.0 with 83.3% expressing high satisfaction. Follow-up after 1 month showed that 80% of participants had applied their knowledge in the workplace and 66.7% of companies began ISCC certification preparation. This activity successfully increased the human resource capacity of the oleochemical industry in understanding and implementing ISCC standards, supporting the competitiveness of Indonesian products in the global market that prioritizes sustainability aspects.
EDUKASI BAHAYA PENGGUNAAN OBAT TANPA RESEP DAN PENYALAHGUNAAN OBAT DI DESA MARINDAL 1, PATUMBAK DELI SERDANG Tambunan, Pravil Mistryanto; Barus, Bunga Rimta; Muflihah Fujiko; Ginting, Ernawati
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 5 No. 1 (2025): Agustus 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v5i1.260

Abstract

Kegiatan pengabdian masyarakat ini bertujuan memberikan edukasi tentang bahaya penggunaan obat tanpa resep dan penyalahgunaan obat kepada masyarakat Desa Marindal 1, Patumbak Deli Serdang. Metode yang digunakan adalah ceramah interaktif, diskusi kelompok, dan pembagian leaflet edukasi dengan melibatkan 45 peserta yang terdiri dari ibu-ibu PKK, remaja, dan tokoh masyarakat. Evaluasi dilakukan melalui pre-test dan post-test menggunakan 15 soal pilihan ganda. Hasil menunjukkan peningkatan signifikan pengetahuan peserta dengan rata-rata nilai pre-test 58,7 (SD=18,2) meningkat menjadi 82,4 (SD=12,6) pada post-test, menunjukkan peningkatan 23,7 poin (40,4%, p<0,001). Sebanyak 33 peserta (73,3%) mencapai kategori baik-sangat baik (?75) pada post-test dibandingkan hanya 12 peserta (26,7%) pada pre-test. Tingkat kepuasan peserta mencapai 4,7/5,0 dengan 91,1% menyatakan sangat puas. Follow-up setelah 1 bulan menunjukkan 78% peserta telah menerapkan pengetahuan dalam kehidupan sehari-hari dan 82% peserta telah menyosialisasikan informasi kepada keluarga dan tetangga. Kegiatan ini berhasil meningkatkan kesadaran masyarakat tentang pentingnya penggunaan obat yang rasional dan mengurangi risiko penyalahgunaan obat di tingkat komunitas. Dampak jangka panjang yang diharapkan dari kegiatan ini meliputi keberlanjutan kesadaran yang dihasilkan melalui pembentukan kader kesehatan serta rencana tindak lanjut yang melibatkan kerjasama dengan fasilitas kesehatan setempat untuk memberikan konsultasi berkelanjutan dan monitoring praktik penggunaan obat rasional di masyarakat.
Edukasi Pembuatan Linimen Fresh Oil dari Bahan Alami bagi Masyarakat Kelurahan Empus Kecamatan Bahorok. Tambunan, Pravil Mistryanto; Saputri, Muharni; Rizki, Fanny; Ginting, Ernawaty
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 4 No 1 (2025): Edisi Januari 2025 - Juni 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v4i1.1578

Abstract

Linimen Fresh Oil is a natural-based product with significant potential to support community health, particularly as a topical oil for pain relief and relaxation. This community service program aims to educate the residents of Empus Village, Bahorok District, on the production of Linimen Fresh Oil. The program is designed to enhance community knowledge and skills in utilizing local natural resources as raw materials for health products. The implementation methods include lectures, hands-on demonstrations, and intensive mentoring for participants. The ingredients used include coconut oil, essential oils such as peppermint and eucalyptus, and local herbal extracts readily available in the area. During the program, participants were taught simple yet effective formulation techniques, including blending, packaging, and storage procedures. Evaluation was conducted through pre-test and post-test surveys to measure participants' knowledge improvement and practical assessments to evaluate their skills. The results demonstrated a significant increase in participants’ understanding of the benefits and production techniques of Linimen Fresh Oil. Additionally, participants successfully produced the liniment independently, meeting quality standards for personal use and potential small-scale businesses. This program is expected to contribute to community self-reliance, local resource management, and economic well-being by developing natural-based products.
Co-Authors Anna Juniar Barus, Bunga Rimta Fanny Rizki Sembiring Ginting, Ernawati Ginting, Ernawaty Hanief, Said Januarti, Ria Lubis, Salmah Handayani Marfitania, Taranipa Muflihah Fujiko Nurmala Sari Paramitha, Ratih Rajali, Mariany Saputri, Muharni Siahaan, Desi Natalia Sihotang, Supran Hidayat Tambunan, Ika Julianti