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All Journal Pharmascience Jambura Journal of Health Sciences and Research Indonesian Journal of Pharmaceutical and Clinical Research Journal of Pharmaceutical and Health Research Mejuajua Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Indonesian Journal of Science and Pharmacy
Ginting, Ernawaty
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Perbandingan Kadar Fenolik Total Air Rebusan dan Ekstrak Etanol Daun dan Batang Sawi Langit (Cyanthillium cinereum (L.) H.Rob) Saputri, Muharni; Yulia, Rahma; Febriani, Yessi; Ginting, Ernawaty; Amara, Saniatul; Zulkhaira, Zulkhaira; Utami, Intan Putri
Journal of Pharmaceutical and Health Research Vol 5 No 1 (2024): February 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i1.4578

Abstract

Sky mustard is one of the herbaceous plants used by the community to treat diseases such as inflammation, malaria and fever. This herbaceous plant is believed to have secondary metabolites such as phenolics which have many functions. The aim of this research was to determine the total content of phenolic compounds in leaves and stems of sky mustard greens (Cyanthillium cinereum (L.) H.Rob). This research is experimental in nature, including collecting plant material, identifying plants, cold extraction using the maceration method using ethanol and boiled water as a solvent, phytochemical screening, and determining the total phenolic content of boiled water and equivalent ethanol extract of leaves and stems (Gallic Acid Equivalent (GAE)) or gallic acid by colorimetric method using reagents Folin-ciocalteu a wavelength of 760 nm using UV-Visible spectrophotometry. The result of phytochemical screening of sky mustard leaves and stems contain alkaloids, steroids, saponins, flavonoids, tannin, glycosides and phenols. The result showed that phenol levels were greater in the leaves than in the stem the ethanol solvents attracted more phenolic compounds than boiling, and the phenol by boiling was higher at 5 minutes at 0,649 mg/g GAE. For phenolic compounds using ethanol solvent, there was a yield of 748,33 mg/g extract.
Edukasi Pencegahan Penyakit Diabetes Menggunakan Obat Herbal di Lingkungan Pengajian Mesjid Namira Medan Muflihah Fujiko; Muharni Saputri; Ginting, Ernawaty; Fanny Rizki; Tambunan, Pravil Mistriyanto
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 4 No. 1 (2024): Agustus 2024
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v4i1.156

Abstract

Diabetes merupakan salah satu penyakit kronis yang ditandai dengan terjadinya peningkatan gula dalam darah yang dapat menyebabkan kerusakan serius pada jantung, pembuluh darah, mata, ginjal dan saraf. Pengobatan diabetes saat ini banyak dilakukan dengan menggunakan obat-obatan alami dari bahan alam, diantaranya adalah jahe, kulit kayu manis, pare, daun sambung nyawa, daun tapak dara, dan daun mimba. Banyak masyarakat yang belum mengetahui manfaat dari penggunaan bahan alam tersebut sehingga perlu dilakukan edukasi dengan melakukan penyuluhan kepada masyarakat. Metode yang dilakukan adalah melalui presentasi. Hasil kegiatan ini bertujuan meningkatkan pengetahuan masyarakat terkait penggunaan bahan alam sebagai terapi pencegahan penyakit diabetes
FORMULATION AND TEST OF ANTIOXIDANT CREAM PREPARATION OF ETHANOL EXTRACT OF MENTENG LEAVES (Baccaurea Racemosa) AS A SKIN MOISTURIZER Sitompul, Rowina Trinida; Sudewi, Sudewi; Febriani, Yessi; Ginting, Ernawaty
Jurnal Pharmascience Vol 11, No 2 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.18571

Abstract

Kosmetik sudah menjadi kebutuhan bagi kalangan wanita karena meningkatkan kepercayaan diri. Namun bahan berbahaya juga sering digunakan dalam pembuatan kosmetik sehingga menimbulkan kerusakan pada kulit. Daun menteng dengan nama latin Baccaurea racemosa mengandung metabolit sekunder yang bermanfaat bagi kulit.  Tujuan dari penelitian ini adalah memformulasikan ekstrak daun menteng sebagai sediaan krim pelembab dengan konsentrasi tertentu. Daun menteng dimaserasi dengan etanol 96% dan ditentukan metabolit sekunder yang terkandung. Kemudian diformulasikan menjadi sediaan krim dengan konsentrasi 1,5%, 2% dan 3% dan dilakukan pemeriksaan mutu fisik sediaan yang meliputi uji homogenitas, uji pH, uji tipe emulsi, uji stabilitas, uji iritasi, uji efektivitas kelembaban dan uji aktivitas antioksidan. Hasil rendemen yang diperoleh sebesar 14%. Metabolit sekunder yang teridentifikasi adalah alkaloid, flavonoid, saponin, tanin dan terpenoid. Sediaan krim dengan konsentrasi 3% yang terbaik karena homogen dan stabil. Sediaan tersebut tidak mengiritasi kulit karena pH sediaan sesuai dengan pH kulit. Kemampuan dalam melembapkan kulit sebesar 97% dan nilai IC50 sebesar 35,67 ppm. Jadi, ekstrak daun menteng bisa diformulasikan ke dalam sediaan krim yang berpotensi sebagai pelembab kulit tanpa menimbulkan iritasi. Kata Kunci: Antioksidan, Daun Menteng, Krim, Pelembab, IC50 Cosmetics have become a necessity for women because they increase their confidence. However, harmful ingredients are also often used in the manufacture of cosmetics so that they cause damage to the skin. Menteng leaves with the Latin name Baccaurea racemosa contain secondary metabolites that are beneficial to the skin.  The purpose of this study is to formulate menteng leaf extract as a moisturizing cream preparation with a certain concentration. Menteng leaves macerated with 96% ethanol and determined the skunder metabolites contained. Then it is formulated into cream preparations with concentrations of 1.5%, 2% and 3% and physical quality checks of the preparation are carried out which include homogeneity tests, pH tests, emulsion type tests, stability tests, irritation tests, moisture effectiveness tests and antioxidant activity tests. The yield obtained is 14%. The secondary metabolites identified were alkaloids, flavonoids, saponins, tannins and terpenoids. Cream preparations with a concentration of 3% are best because they are homogeneous and stable. The preparation does not irritate the skin because the pH of the preparation is in accordance with the pH of the skin. The ability to moisturize the skin by 97% and IC50 value of 35.67 ppm. So, menteng leaf extract can be formulated into cream preparations that have the potential to moisturize the skin without causing irritation.
The Effect of Adding Ethanol Extract of Pomegranate Peel (Punica Granatum L.) on the Sun Protection Factor (SPF) Value of Sunscreen Cream Combination of Avobenzone and Octyl Methoxycinnamate Julianty, Siti Muliani; Ginting, Ernawaty; Sudewi, Sudewi; Rizki, Fanny; Nadia, Syarifah; Saputri, Muharni
Indonesian Journal of Science and Pharmacy Vol. 2 No. 1 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v2i1.57

Abstract

The compounds contained in pomegranate skin are phenolic acids, flavonoids, and tannins, including anthocyanidin, gallic acid, ellagic acid, ellagitannin, gallotanin, catechin, quercetin, which have antioxidant properties. The benefits of pomegranate peels are that they treat health problems and maintain beautiful skin. This research aimed to see the effect of adding pomegranate peel (Punica granatum L.) ethanol extract on the Sun Protection Factor (SPF) value of a combination of avobenzone and octyl methoxycinnamate sunscreen cream. This research was carried out using experimental methods. The formulation of sunscreen cream preparations uses pomegranate peel ethanol extract in various concentrations. The cream was evaluated to determine its Sun Protection Factor (SPF) value, organoleptic test, homogeneity, pH, emulsion type, and irritation test. The organoleptic test results showed that the cream produced in the blank had no odor and was white, while the cream with the addition of pomegranate peel ethanol extract had a distinctive smell and was brown. The emulsion type test shows the oil in the water type.  The addition of pomegranate peel ethanol extract to each formula increased the sun protection factor (SPF) value of sunscreen preparations. The average SPF value of each formula was FI 12.5956, FII 13.9673, FIII 16 .8205, FIV 17.9187, and FV 18.8437.
Edukasi Pembuatan Linimen Fresh Oil dari Bahan Alami bagi Masyarakat Kelurahan Empus Kecamatan Bahorok. Tambunan, Pravil Mistryanto; Saputri, Muharni; Rizki, Fanny; Ginting, Ernawaty
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 4 No 1 (2025): Edisi Januari 2025 - Juni 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v4i1.1578

Abstract

Linimen Fresh Oil is a natural-based product with significant potential to support community health, particularly as a topical oil for pain relief and relaxation. This community service program aims to educate the residents of Empus Village, Bahorok District, on the production of Linimen Fresh Oil. The program is designed to enhance community knowledge and skills in utilizing local natural resources as raw materials for health products. The implementation methods include lectures, hands-on demonstrations, and intensive mentoring for participants. The ingredients used include coconut oil, essential oils such as peppermint and eucalyptus, and local herbal extracts readily available in the area. During the program, participants were taught simple yet effective formulation techniques, including blending, packaging, and storage procedures. Evaluation was conducted through pre-test and post-test surveys to measure participants' knowledge improvement and practical assessments to evaluate their skills. The results demonstrated a significant increase in participants’ understanding of the benefits and production techniques of Linimen Fresh Oil. Additionally, participants successfully produced the liniment independently, meeting quality standards for personal use and potential small-scale businesses. This program is expected to contribute to community self-reliance, local resource management, and economic well-being by developing natural-based products.
EFEKTIVITAS EKSTRAK DAUN BINAHONG SEBAGAI ANTIBAKTERI DALAM HAND SANITIZER Ginting, Ernawaty; Tambunan, Ika Julianti; Dachi, Kanne; Putri, Nurul Maulida; Pratama, Danawan Heru; Gori, Iradat Novtworian; Hasibuan, Munawwaroh
Jambura Journal of Health Sciences and Research Vol 7, No 1 (2025): JANUARI: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v7i1.28704

Abstract

Hand sanitizer adalah alat yang sangat baik untuk menghilangkan bakteri di tangan yang dapat menyebabkan penyakit seperti Staphylococcus aureus dan Escherichia coli.  Dengan mengekstraknya daun binahong yang mengandung zat antibakteri flavanoid dan tanin dapat digunakan untuk membuat semprotan pembersih tangan alami. Kebaruan penelitian ini untuk mengetahui efektivitas ekstrak daun binahong sebagai antibakteri dalam Hand Sanitizer. Penelitian ini bertujuan untuk mengevaluasi efektivitas ekstrak daun binahong dalam hand sanitizer sebagai antibakteri dengan menggunakan etanol p.a. Sebagai langkah-langkahnya, dilakukan ekstraksi dan skrining daun binahong, pemilihan formula dasar, formulasi, uji antibakteri, dan evaluasi hand sanitizer. Hasil penelitian menunjukkan bahwa sediaan hand sanitizer daun sirih merah paling disukai formula F3. Hasil uji aktivitas zona hambat menunjukkan bahwa formula F3 memiliki daya hambat paling besar yaitu 18,75 mm terhadap bakteri Escherichia coli. Sebagai perbandingan, formula F1 memiliki daya hambat terbesar yaitu 15,73 mm terhadap bakteri Staphylococcus aureus. Semua pengujian pada sediaan Hand sanitizer memenuhi persyaratan berdasarkan SNI, yang berarti pengujian antibakteri dapat dikatakan “aktif”. Kesimpulannya bahwa ekstrak daun binahong efektif sebagai antibakteri dan dapat digunakan pada hand sanitizer.
FORMULASI DAN UJI ANTIOKSIDAN EKSTRAK ETANOL DAUN BINAHONG (Anredera Cordifolia) SEBAGAI GEL PELEMBAP Ginting, Ernawaty; nadia, syarifah; Nurul Karima; rossela; Ovalina Sylvia Br Ginting
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 2 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i2.17967

Abstract

Dry skin is often caused by air pollution and sun exposure. Binahong leaves (Anredera Cordifolia) contain flavonoids that can keep the skin moisturized. The gel formulation of binahong leaf extract was chosen because it has good penetration, making it an effective solution for dry skin.This study began by macerating the simplicia of binahong leaves (Anredera Cordifolia) with ethanol p.a (1:10), then formulated into gel preparations with concentrations of 2.5%, 3% and 3.5% with CMC, TEA, nipagin, glycerin and propylene glycol as gel preparation ingredients. Then the physical quality of the preparation was checked which included organoleptic test, pH test, homogeneity test, stability test, dispersion test, adhesion test, irritation test, liking test and viscosity test. In addition, moisture tests and antioxidant tests were carried out using the DPPH method. The gel formulation made has met the physical quality requirements of the preparation, namely all preparations are homogeneous, stable and do not irritate the skin. The pH value is 4.5-4.8, the spread power is 5.5-6.8 cm, the adhesion value is 15-24 seconds and the viscosity value is 12,400-22,299 m.Pas. The amount of antioxidants in formulation 3 was 84.61 mcg/mL ± 0.05 with the strong category and the recovery percentage was 66.94% with a very humid scale. The amount of antioxidants in formulation 2 was 118.56 mcg/mL ± 0.00 with the medium category and the percent recovery was 54.39% with a humid scale. The number of antioxidants in formulation 1 was 163.98 mcg/mL ± 5.71 with the weak category and the recovery percentage was 44.50% with the dry scale. Formulation 3 with a concentration of 3.5% has the highest antioxidants and recovery.
Co-Authors Amara, Saniatul Dachi, Kanne Fanny Rizki Sembiring Febriani, Yessi Gori, Iradat Novtworian Hasibuan, Munawwaroh Julianty, Siti Muliani Muflihah Fujiko Muharni Saputri Nadia, Syarifah Nurul Karima Ovalina Sylvia Br Ginting Pratama, Danawan Heru Putri, Nurul Maulida rossela Saputri, Muharni Sitompul, Rowina Trinida Sudewi Sudewi Tambunan, Ika Julianti Tambunan, Pravil Mistriyanto Tambunan, Pravil Mistryanto Utami, Intan Putri Yulia, Rahma Zulkhaira, Zulkhaira