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TINGKAT EFEKTIVITAS DETEKSI MANDIRI HIPERTENSI OLEH KOMUNITAS DI PUSKESMAS GAJAHAN Myrtha, Risalina; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 28 No. 1 (2024): June 2024
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v28i1.2323

Abstract

Pengabdian ini bertujuan untuk menguatkan peran komunitas dalam kemandirian kesehatan melalui deteksi mandiri hipertensi dan kelainan irama jantung di Puskesmas Gajahan. Peningkatan prevalensi penyakit tidak menular, khususnya hipertensi dan fibrilasi atrium, memerlukan intervensi berbasis komunitas yang efektif untuk mengurangi beban penyakit ini. Metode pengabdian ini melibatkan pada kader kesehatan di wilayah kerja Puskesmas Gajahan dengan melakukan edukasi dan pelatihan kepada kader puskesmas Gajahan mengenai cara deteksi mandiri hipertensi dan kelainan irama jantung. Pelatihan ini mencakup cara pengukuran tekanan darah mandiri dan cara deteksi mandiri kelainan irama jantung dengan cara meraba nadi sendiri (MENARI), serta edukasi mengenai faktor risiko dan tanda-tanda kedua penyakit ini. Hasil dari implementasi pelatihan ini menunjukkan peningkatan pengetahuan dan keterampilan masyarakat dalam mendeteksi dini hipertensi dan kelainan irama jantung. Partisipan yang mengikuti pelatihan mampu melakukan pemeriksaan tekanan darah dan deteksi kelainan irama jantung secara mandiri dengan benar. Selain itu, terdapat peningkatan kesadaran masyarakat tentang pentingnya pemeriksaan kesehatan rutin dan perubahan gaya hidup untuk mengurangi risiko penyakit tidak menular. Kesimpulannya, penguatan peran komunitas melalui edukasi dan pelatihan deteksi mandiri terbukti efektif dalam meningkatkan kemandirian kesehatan masyarakat di wilayah kerja Puskesmas Gajahan.
Role of Gamma-Glutamyl Transferase, High Sensitivity C Reactive Protein and Apolipoprotein B as A Marker of Disease Severity in Psoriasis Shofiyah, Laily; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Aprilningsih, Hendrastutik; Myrtha, Risalina; Kuncorowati, Niken Dyah Aryani; Suwandono, Adji; Nugroho, Novianto Adi; Sari, Maria Galuh Kamenyangan; Dyanneza, Frieska
Gema Lingkungan Kesehatan Vol. 23 No. 3 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i3.285

Abstract

Psoriasis can develop into systemic psoriasis, which primarily affects the liver, bile ducts, and cardiovascular system. Assessing the severity of psoriasis was crucial for determining treatment and cardiovascular disease risk. The aim of this study was to determine the role of Gamma-Glutamyl Transferase (GGT), High Sensitivity C-Reactive Protein (HS-CRP), and apolipoprotein B (APO B) in assessing the severity of psoriasis. Methods: This study was a cross-sectional, observational analytic study. A total of 33 psoriasis patients were tested for GGT, HS-CRP, APO B levels, and the Psoriasis Area and Severity Index (PASI) score. Results: The average GGT level was 70.75±56.47 u/L, the average HS-CRP level was 0.91±1.03 mg/L, the average APO B level was 110.09±26.47 mg/dL, and the average PASI score was 11.70±4.54. 12.1% of patients had mild psoriasis, 51.5% had moderate psoriasis, and 36.4% had severe psoriasis. There was a positive and strong correlation between GGT and PASI score, HS-CRP and PASI score, and APO B and PASI score. The multivariate correlation between GGT, HS-CRP, and APO B with PASI score had a value of R = 0.874, F = 31.145, p = <0.001. Conclusion: The multivariate correlation between GGT, HS-CRP, and APO B with PASI scores shows a positive and strong correlation, thus it useful for assessing the severity of psoriasis and evaluating the likelihood of cardiovascular disease.
Rice growth and the associated phosphate solubilizing bacteria on an Alfisol treated with insecticide and endophytes inoculum Shofiyah, Laily; Sudadi, Sudadi; Cahyani, Vita Ratri
Journal of Degraded and Mining Lands Management Vol. 12 No. 5 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2025.125.8481

Abstract

The long-term use of excessive amounts of chemical fertilizers and pesticides adversely affects soil fertility, crop productivity, and biodiversity of soil and endophytes microbes. This study evaluated the ability of endophytic bacteria isolated from rice plants to enhance soil fertility, promote plant growth, and induce rice plant resistance on Alfisols treated with insecticide 10x usage dose (chlorantraniliprole 100 g L-1 and thiamethoxam 200 g L-1), and also assessed the diversity and population density of the associated phosphate solubilizing rhizospheric and endophytic bacteria. Three isolates of Burkholderia sp. YErOI-1 (I1), Bacillus sp. NErOI-2 (I2), Burkholderia sp. PElOI-3 (I3) and a mixture of three isolates (I4) were tested in combination with (P1) and without (P0) insecticide treatments in the pot cultivation of rice Inpari 32 using Alfisols in a completely randomized factorial design with three replications. The results showed that the control (I0P0) demonstrated higher plant growth compared to I0P1, indicated insecticide treatment resulted in toxicity effect. Among all the treatments, I2P0, I2P1, and I1P0 yielded the highest plant growth, whereas the lowest was indicated by I1P1. The rice associated phosphate solubilizing rhizospheric and endophytic bacteria indicated the highest population density and diversity index on the treatments I3P0 and I3P1 which significantly correlated with the highest P concentration and P uptake in these two treatments. Isolate I2 showed the strongest effect in inducing plant growth to insecticide resistance, in contrast isolate I1 showed no support in inducing plant resistance to insecticide. Further study is needed to examine the effect of the present assessed endophytes in other type of pesticide treatments.
Serum Angiopoeitin Like-4 As An Early Detection Marker Of Diabetic Kidney Disease Habsari, Pusparini; Ariningrum, Dian; Shofiyah, Laily
Eduvest - Journal of Universal Studies Vol. 4 No. 6 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i6.1459

Abstract

Diabetic kidney disease (DKD) is a long-term complication of diabetes mellitus (DM). The gold standard for diagnosis of DKD is kidney biopsy, but it is difficult to perform. Several clinical conditions have found an association between higher ANGPTL4 plasma levels in DKD. Methods: A total of 87 patients with Type 2 DM were analysed using an observational analytic method with a cross-sectional design. The study subjects were divided into DKD and non DKD groups, then serum ANGPTL4 was measured using the sandwich ELISA method. Furthermore, ANGPTL index cutoff was determined. Several other variables including glycemic control, duration of DM, history of hypertension, and dyslipidemia were analysed for their association with DKD and non DKD groups. The study continued by conducting multivariate analysis with logistic regression. Results: A total of 23 (26.4%) subjects were classified as DKD and 64 (73.6%) subjects as non DKD. ANGPTL cutoff determination of 16.64 ng/mL had a sensitivity and specificity of 87% and 51.6%, respectively. Bivariate analysis showed glycaemic control, duration of DM, and serum ANGPTL4 (p=0.044; p=0.009; p=0.014) were associated with the incidence of DKD. Multivariate analysis showed that serum ANGPTL4 with a cutoff of >16.64 ng/mL could be used as an independent predictor of DKD incidence with an adjusted OR of 6.73 (95%CI= 1.79-25.30; p=0.005). Conclusion: serum ANGPTL4 is an independent predictor of DKD. Suggestion: Urine sampling for UACR examination twice, periodic examination of serum ANGPTL4 levels to assess the progressiveness of DKD.