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All Journal Jurnal Kartika Kimia
Annifah, Riri Uswatun
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education

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A Systematic Review: Chitosan/ Poly (vinyl alcohol) based Hydrogel composites for Drug Delivery Material Annifah, Riri Uswatun; Kadarohman, Asep; Khoerunnisa, Fitri; Nurhayati, Mita; Hendrawan, Hendrawan; Anwar, Budiman
Jurnal Kartika Kimia Vol 7 No 1 (2024): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v7i1.254

Abstract

This review article aims to systematically describe the synthesis methods, characterization, and performances of CS/PVA based hydrogel composites as drug delivery materials. The literature review was conducted through ScienceDirect and Google Scholar, where the article selection is based on Scopus index in the Q1 and Q2 categories within the past 5 years. The synthesis of CS/PVA hydrogel was performed using various methods, including crosslinking, freeze-thaw, and sol-gel. The synthesis methods of hydrogel composites included crosslinking, freeze-thaw, and sol-gel. Characterization of hydrogel composites was conducted using FTIR spectroscopy, SEM, and swelling ratio measurement. CS/PVA-based hydrogel composites as drug delivery materials have been successfully synthesized using crosslinker, freeze-thaw and sol-gel methods. FTIR spectra indicated that drug was successfully loaded into CS/PVA based hydrogel composite matrix, involving the hydrogen bonding as predominant mechanism of interaction between precursors and drug functionalities. The best swelling capacity was obtained in the CS/PVA/Tetracycline based hydrogel composites, up to 949%. The SEM images indicated the homogeneous morphological structure and surface of hydrogel composites. The CS/PVA/Tetracycline based hydrogel composites exhibited the largest cumulative drug release of 99.44%. The drugs loaded CS/PVA hydrogel composites are promising as a drug delivery material.
Review on Synthesis, Properties, and Performances of Polymer/ Metal Organic Framework (MOF) composites membranes for water filtration application Ashfiya, Putri Sayyida; Khoerunnisa, Fitri; Nurhayati, Mita; Kadarohman, Asep; Sanjaya, Eli Hendrik; Hendrawan, Hendrawan; Sonjaya, Yaya; Aziz, Hafiz Aji; Annifah, Riri Uswatun; Iasya, Yurin Karunia Apsha Albaina
Jurnal Kartika Kimia Vol 8 No 1 (2025): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v8i1.871

Abstract

Mixed matrix membranes (MMMs) have gained considerable attention as a cutting-edge filtration technology, leveraging the combined advantages of polymer and inorganic fillers. Metal-organic frameworks (MOFs), as a nanoporous materials, are regarded as highly effective fillers in MMM, significantly enhancing molecular separation efficiency. This article provides a comprehensive review of the synthesis, properties, and performance of polymer/MOFs-based MMMs. A comprehensive literature search was conducted using ScienceDirect and Google Scholar with keywords such as metal-organic framework, MMMs, polymers, filler, and membrane filtration. Polymer/MOFs-based MMMs are synthesized using techniques including in situ and layer-by-layer assembly methods. The MMMs exhibit porosity distribution ranges from57 to 78.3%, contact angle ranges from 45° to 75.27°. The MMMs have also demonstrated exceptional performance in water permeability and bovine serum albumin (BSA)/salts rejection reached up to 94.03 L/m2.h and 99.8%, respectively. These finding highlight the significant potential of polymer/MOFs-based MMMs for advanced water filtration application.
Co-Authors Asep Kadarohman Ashfiya, Putri Sayyida Aziz, Hafiz Aji Budiman Anwar Eli Hendrik Sanjaya Fitri Khoerunnisa Hendrawan Hendrawan Iasya, Yurin Karunia Apsha Albaina Nurhayati, Mita Yaya Sonjaya