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All Journal Majalah Obat Tradisional Jurnal Penelitian Pendidikan IPA (JPPIPA) Chemistry Indonesian Journal of Chemical Research Jurnal Abdimas Kesehatan
Astuti, Ayun Dwi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Engineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Antibacterial Activity and Toxicity of Honey Derived from Bone, South Sulawesi, Indonesia Zakaria, Zakaria; Misriyani, Misriyani; Astuti, Ayun Dwi; Masyita, Ayu
Indonesian Journal of Chemical Research Vol 10 No 3 (2023): Edition for January 2023
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.10-zak

Abstract

Honey is a sweet substance produced by honey bees from the nectar of flowers or other parts of plants. Honey obtained from Bone, in South Sulawesi, has been extracted and tested for antibacterial activity and toxicity. Honey was macerated with methanol to obtain a crude extract. Methanol crude extract was then partitioned successively with n-hexane and ethyl acetate to obtain ethyl acetate and methanol fraction. Antibacterial activity test was performed by agar diffusion method against Escherichia coli and Staphylococcus aureus. Methanol extract, ethyl acetate fraction, and methanol fraction showed an inhibition zone against E. coli at 10.10, 10.05, and 8.40 mm, respectively with amoxicillin as a positive control (20.05 mm). Also against S. aureus, inhibition zone was obtained at 11.90, 9.30, 8.60, and 13.70 mm for methanol extract, ethyl acetate fraction, methanol fraction, and amoxicillin, respectively. The greatest inhibition zone was obtained from methanol extract against E. coli and S. aureus, both including the strong category. The LC50 value of methanol extract and methanol fraction was 273.57 µg/ml and 765.66 µg/ml, respectively, categorized as toxic against Artemia salina, while ethyl acetate fraction was not toxic.
Scoping Review: Study of Herbs Consumption for Self-Medication in Indonesia 2019-2022 Azzahra, Fatimah; Astuti, Ayun Dwi; Arifin, Bustanul; Alam, Gemini
Majalah Obat Tradisional Vol 29, No 3 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.94091

Abstract

Indonesia is a country that has high biodiversity and is rich in traditional medicine from natural ingredients or herbs. One use of these natural ingredients is as a treatment for self-medication. Many previous studies have been carried out but none has reviewed it systematically, especially during the Covid-19 pandemic. This research was carried out systematically using the PRISMA statement approach using the Google Scholar data bank. Out of 2,214 papers in the 2019-2022 period,  45 articles/scientific papers papers met the criteria, including inclusion and exclusion criteria, for a description/profile of the use of natural ingredients or herbs as self-medication for traditional medicine. The central region of Java (D.I.Y Yogyakarta and Central Java) is the region with the largest number of articles. The distinctiveness of Indonesia's approach to self-medication lies in its utilization of various natural elements to address similar ailments, which can be attributed to geographical factors, cultural beliefs, and diverse knowledge across different regions. Meanwhile, Covid-related studies were very limited due to the availability or the preference for chemical self-medication.
Edukasi Penyalahgunaan Obat Resep terhadap Kesehatan Jiwa Remaja di Sekolah Menengah Pertama Negeri 2 Kecamatan Galesong Utara Kabupaten Takalar Fitriani, Nurlaila; Astuti, Ayun Dwi; Fadilah, Nur; Febrianty, Eva; Azzahra, Nur Inaayah; Nurazizah, Nurazizah; Rasak, Risna
Jurnal Abdimas Kesehatan (JAK) Vol. 7 No. 2 (2025): Juni
Publisher : Universitas Baiturrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jak.v7i2.819

Abstract

Prescription drug abuse has been widely practiced by adolescents in Indonesia. Seeing this condition requires an intervention that can increase adolescent knowledge related to prescription drug abuse. Psychoeducation for students of SMPN 2 North Galesong is one of the interventions to educate students, teachers, and parties related to the impact of prescription abuse among adolescents. The results of the implementation of this community service obtained that students' knowledge related to prescription drug abuse predominantly increased as evidenced by the highest score in the pre-test of only 60 to 100 in the post-test. In conclusion, there was an increase in knowledge in students of SMPN 2 North Galesong after being given psychoeducation related to prescription drug abuse. The Hasanuddin University community service team hopes that this psychoeducation can prevent prescription drug abuse in adolescents
Comparison of Antioxidant Activity of Stem Bark, Stem Wood, and Leaf Extracts of Bayur Plant (Pterospermum Subpeltatum C.B.Rob) Zakaria; Soekamto, Nunuk Hariani; Nur, Suriani; Astuti, Ayun Dwi
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.9721

Abstract

Antioxidants play a role in preventing and repairing damage to human cells. Searches for antioxidant sources continue to be carried out including in P. subpeltatum plants. This study aims to compare the antioxidant activity of the bark, wood, and leaves of P. subpeltatum C.B. Rob plants. The materials were dried and then shaved to a fineness level of 80 mesh. Materials were extracted using the maceration method with ethanol solvent. The macerate was filtered and the filtrate obtained was concentrated with an evaporator. The three extracts were tested for antioxidants using the DPPH (1,1-diphenyl-2-picrylhydrazyl) Free radical scavengers method, ascorbic acid was used as a comparison. Absorbances was measured using UV-Vis spectroscopy. Each material was made in 5 concentrations. The IC50 value was calculated using the Blois regression equation. The results of the antioxidant test were obtained consecutively: stem wood with an IC50 value = 3.39 μg/mL, stem bark = 5.15 μg/mL, and leaf = 258.58 μg/mL, the IC50 value of ascorbic acid was 2.79 μg/mL. Based on these data, it shows that the antioxidant activity of stem wood and stem bark is in the high category, although still lower than ascorbic acid, while the leaf are included in the weak category.
Co-Authors Azzahra, Nur Inaayah Bustanul Arifin Fatimah Azzahra Febrianty, Eva Gemini Alam Masyita, Ayu Misriyani Misriyani Nunuk Hariani Soekamto NUR FADILAH Nurazizah Nurazizah, Nurazizah Nurlaila Fitriani Rasak, Risna Suriani Nur, Suriani Zakaria Zakaria Zakaria