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Risk Factor Profile and Role of Cardiovascular Disease Outreach Program by Experts in Rural Communities: A Pilot Study in Magetan Regency, Indonesia Wungu, Citrawati Dyah Kencono; Elvaretta, Clarissa; Palupi, Dian Eka Roro; Qurnianingsih, Ema; Susilo, Hendri; Lukitasari, Lina; Humairah, Ira; Khaerunnisa, Siti; Soetjipto, Soetjipto; Handajani, Retno; Safitri, Indri; Ummah, Fithriyah Cholifatul; Waskito, Langgeng Agung; Prabowo, Gwenny Ichsan; Wiratama, Bayu Satria; Amin, Indah Binti Mohd
Jurnal Keperawatan Soedirman Vol 19 No 2 (2024): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2024.19.2.10947

Abstract

Cardiovascular outreach programs and risk factors profiling have been regarded as key strategy in preventing and controlling cardiovascular diseases as the leading global causes of death worldwide, especially when being conducted by a professional. This pilot study aims to evaluate the effectiveness of a cardiovascular outreach program in Plaosan District, Magetan Regency, to improve knowledge and influence changes in the community’s behavior related to cardiovascular risk factors. This study was conducted by providing educational interventions and profiling cardiovascular risk factors on 90 adults using consecutive sampling method. Health education was performed by experts and evaluated by pre-post tests before and after the material delivery. Statistical analysis was used to assess the relationship of risk factors that can contribute to cardiovascular disease. This study showed a significant increase in the participants' knowledge score after the intervention (p = 0.007). There were several risk factors for cardiovascular disease in the participants, with the highest risk prevalence being diabetes mellitus (33.33%). Six participants (6.67%) had abnormal electrocardiography results. In conclusion, our study showed a high prevalence of cardiovascular risk factors in rural communities and the importance of cardiovascular outreach programs by experts to improve the understanding of cardiovascular disease in a specific community.
Severe Inflammatory Bowel Disease Manifestations in a Patient with Post-Acute COVID-19 Syndrome (PACS): A Case Report and Literature Review Riswanto, Arival Yanuar; Waskito, Langgeng Agung; Arfijanto, Muhammad Vitanata; Imro'ati, Tri Asih; Nasronudin, Nasronudin
Indonesian Journal of Tropical and Infectious Disease Vol. 14 No. 1 (2026): January - April Edition
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v14i1.78750

Abstract

Post-acute COVID-19 syndrome (PACS) refers to the persistence or recurrence of symptoms lasting more than four weeks after the acute phase of COVID-19. Based on symptom duration, it is classified as subacute symptomatic COVID-19 or long COVID. The interaction between SARS-CoV-2 and the angiotensin-converting enzyme 2 (ACE2) receptor triggers immune system activation, cytokine production, and redistribution of immune cells. Impaired self-tolerance hampers immune reconstitution. In combination with environmental and genetic factors, this dysregulated immune response may act as a potential trigger for autoimmune disease, such as Inflammatory Bowel Disease (IBD). This article aims to describe a possible case of IBD, specifically Crohn’s disease developing as a manifestation of PACS. A 57-year-old male presented with hematemesis, nausea, and decreased appetite four weeks after recovering from COVID-19 infection. Esophagogastroduodenoscopy (EGD) was performed and the results were esophagitis, gastroduodenitis, and multiple lacerations of the gastric corpus. Colonoscopy demonstrated findings consistent with Crohn’s disease, including mucosal ulcerations and segmental inflammation. With supportive therapy and administration of 300 mg of infliximab, 500 mg of mesalazine three times daily, and 125 mg of methylprednisolone intravenously every 24 hours, the patient demonstrated clinical improvement and resolution of bleeding. This case highlights a possible association between PACS and de novo Crohn’s disease, suggesting that post-viral immune dysregulation following COVID-19 may unmask or trigger IBD in predisposed individuals. Clinicians should remain vigilant for gastrointestinal manifestations suggestive of IBD in patients with persistent digestive symptoms after COVID-19 infection, as early recognition and targeted therapy are essential for improving outcomes.