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All Journal Folia Medica Indonesiana Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Jurnal Pengabdian kepada Masyarakat Nusantara CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Formosa Journal of Science and Technology (FJST) Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Scientica: Jurnal Ilmiah Sains dan Teknologi Buletin Pengabdian
Humairah, Ira
Department Of Physiology And Medical Biochemistry, Faculty Of Medicine, Universitas Airlangga, Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Prevention and Early Detection of Metabolic Syndrome in Household Community, Surabaya Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Siti Khaerunnisa; Gwenny Ichsan Prabowo; Suhartati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15747

Abstract

Introduction. Metabolic syndrome is a collection of factors believed to increase the risk of atherosclerosis and type 2 diabetes mellitus. The incidence of metabolic syndrome in young adults is increasing, especially in Asian countries. Therefore we need efforts to increase knowledge in society about this disease. Aim. We conducted a socialization program on prevention and early detection of metabolic syndrome in household community to increase public knowledge about this disease.Method. This program was conducted in August 2017 in Wonokromo District, Surabaya. The participants in the activity consisted of 32 people from household community. The activity consisted of blood sampling collection, body weight, and abdominal circumference measurement for risk factor assessment, pre-test, socialization of metabolic syndrome, and post-test.Results. From the results of the pre and post test, we found an increase knowledge of 76.9% participants. The laboratory test results for early detection of metabolic syndrome showed 37.5% of participants had metabolic syndrome. We also found a significant positive correlation between body weight and abdominal circumference (p = 0.000, r = 0.867). There was also a significant negative correlation between body weight and HDL (p = 0.004, r = -0.494), between abdominal circumference and HDL (p <0.05, r = -0.376), and between TG and HDL (p <0.05, r = -4.22).Conclusion. Socialization and early detection of metabolic syndrome can increase knowledge, awareness, and detection of metabolic syndrome in the household community.
The Improvement of Community Knowledge, Attitudes and Practices After Covid-19 Socialization Siti Khaerunnisa; Irmi Syafa'ah; Citrawati Dyah Kencono Wungu; Gwenny Ichsan Prabowo; Retno Handajani; Indri Safitri; Harianto Notopuro; Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Arief Bakhtiar; Suwandito Suwandito; Susi Wahyuning Asih; Zuhrotul Eka Yulis Anggraeni; Ginanjar Sasmito Adi; Ely Rahmatika Nugrahani; Ayesie Natasha Zulka; Soetjipto Soetjipto
Folia Medica Indonesiana Vol. 57 No. 2 (2021): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.653 KB) | DOI: 10.20473/fmi.v57i2.26262

Abstract

This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low attitude, very high practice, high practice, sufficient practice, and low practice were 58.33 ± 30.97, 77.70 ± 22.52, 62.5±21.7, 31±22.2, 6.5±17.1, 65±13.8, 32.3±13.8, 1.25±2.4, 1.25±1.8, respectively. Knowledge pre-test and post-test correlated 0.819 (p=0.001) and a t-test with p=0.003. Attitudes and practices correlated with p=0.001. Socialization of COVID-19 was useful to improve the community knowledge, attitudes, and practices in Rambipuji and Suci Village, Jember District, East Java, Indonesia that could prevent the transmission and inhibit the spread of the COVID-19 pandemic in Indonesia. Furthermore, continuous encouragement of COVID-19 socialization in wide areas was recommended.
SARI ETANOL, ETIL ASETAT ALANG-ALANG (IMPERATA CYLINDRICA) TERHADAP SUPEROXIDE DISMUTASE (SOD) St Khaerunnisa; Sutji Kuswarini; Suhartati Suhartati; Lina Lukitasari; Ira Humairah; Reza Arta BN; Gwenny IP
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 2 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i2.1080

Abstract

Oxidative stress has been considered as a mechanism involved in the pathogenesis and progression of many diseases such as:hypercholesterolemia and atherosclerosis. The objective of this current study was to know the potential antioxidant role of ethanol andethyl acetate extract of reeds (Imperata cylindrica) by investigation in rats fed with a high-cholesterol diet. Imperata cylindrica is richin antioxidants and has a cholesterol-reducing effect. A group of twenty four male albino Wistar rats was divided into four subgroups: anormal diet group (K0), a high-cholesterol diet group (K1), the same diet with ethanol extract of Imperata cylindrica group (K2), and thesimilar diet with ethyl acetate fraction of Imperata cylindrica group (K3),. After the treatment period, the hepatic antioxidant enzymeactivity (Superoxide dismutase/SOD) was determined. The rats fed on high-cholesterol diet with supplementation exhibited a significantelevation in SOD activity (p<0. 05), 61.6±12.4% inhibition, compared to normal animals 37.44±12.2%. The treated animals withethanol and ethyl acetate extract of Imperata cylindrica showed a significantly reduced the level of SOD activity (p<0.05, 29.90±5.6%as well as a 33.49±7.4% inhibition). The level of SOD activity when restored was closer to that in normal animals, signifying reversalof the oxidative stress. The study results showed that the treatment with Imperata cylindrica positively changed the hepatic antioxidantenzyme activities in high fat-diet rats, and thus had potential hypocholesterolemic and antioxidant effects. Imperata cylindrica couldprotect against oxidative stress linked to atherosclerosis and also decrease the atherogenic index.
Mortalitas Pasien COVID-19 dengan Komorbiditas Diabetes Mellitus: Systematic Review Muhammad Rifqi Adinagoro; Ridhwan Biosia Wiratama; Yohanes Widyakusuma E.S; Humairah Humairah; Claudia Clary Navisa; Atika Atika
ANATOMICA MEDICAL JOURNAL | AMJ Vol 4, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/amj.v4i3.8475

Abstract

Latar Belakang: Diabetes mellitus (DM) adalah kelompok penyakit metabolik yang ditandai oleh hiperglikemia yang terjadi akibat kelainan pada sekresi insulin, kerja insulin atau keduanya. Penyakit kronis seperti DM adalah faktor risiko untuk derajat mortalitas dan morbiditas pada pasien COVID-19. Terdapat 42 orang dari 1000 kasus yang menderita COVID-19 dengan DM dengan angka mortalitas sebesar 10%. Penelitian ini diharapkan dapat memberikan gambaran mortalitas penderita COVID-19 yang memiliki komorbiditas DM. Metode: Penelitian ini menggunakan metode systematic review. Kriteria pencarian literatur adalah dengan menggunakan PICO (population, intervention, comparison, and outcome). Penilaian kualitas jurnal referensi dinilai dengan The Center for Review and Dissemination and the Joanna Briggs Institute Guideline sebagai pedoman., sedangkan evaluasi dari systematic review menggunakan checklist PRISMA. Hasil: Penelitian ini menggunakan jurnal referensi yang didapat dari mesin pencarian Scopus, ProQuest, Pubmed, CINAHL dan Science Direct dengan menggunakan keywords dan Boolean operators (AND, OR NOT or AND NOT). Terdapat 15 jurnal yang telah diseleksi dari diskusi komorbiditas DM dengan angka mortalitas pasien COVID-19 dengan hasil terdapat pengaruh signifikan komorbiditas DM terhadap angka kematian pasien COVID-19. Kesimpulan: Mortalitas pada pasien COVID-19 dengan komorbiditas DM lebih tinggi dibandingkan pasien COVID-19 tanpa komorbiditas DM.Kata kunci: COVID-19, diabetes mellitus, komorbid, mortalitas 
The Effect of Ajwa Date (Phoenix dactylifera) Extract on the Histopathology of Pancreatic Islets in Mice with Diabetes Mellitus Arna, Nadhifa; Humairah, Ira; Susanto, Joni; Yuliawati, Tri Hartini
Current Internal Medicine Research and Practice Surabaya Journal Vol. 5 No. 2 (2024): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v5i2.53610

Abstract

Introduction: It is necessary to develop alternative antidiabetic therapies that are safer and more affordable to overcome the high prevalence of diabetes mellitus in Indonesia. Ajwa dates (Phoenix dactylifera) have a high flavonoid content; hence, this study aimed to investigate their effect on streptozotocin-induced diabetes mellitus mice by examining the number of beta cells and the islets of Langerhans. Methods: Twenty-five mice were divided into five groups: a negative control group (K1), a positive control group (K2), and three treatment groups (P1, P2, and P3). The K2, P1, P2, and P3 groups were induced by 100 mg/kg bw of streptozotocin. Additionally, the P1, P2, and P3 groups received oral treatment using ajwa date methanol extract at different doses of 3, 5, and 7 g/kg bw, respectively. The treatment was administered daily for four weeks. The initial analysis included the homogeneity test and the Shapiro-Wilk test. As the data were non-normally distributed, the analysis proceeded with the Kruskal-Wallis test (p<0.05). Results: The comparative analysis revealed significant differences in the number of beta cells among the groups, with a notable decrease observed in the K2 group and an increase in each treatment group. The measurement of the islets of Langerhans exhibited significant differences among the groups, with p=0.001.  Conclusion: The administration of ajwa date methanol extract can affect the number of beta cells and the islets of Langerhans in mice with diabetes mellitus.   Highlights: 1. This original study examined the antioxidant compounds derived from naturally sourced ajwa date (Phoenix dactylifera) extract. 2. Ajwa date extract has the potential to protect against histological damage, specifically to beta cells and pancreatic islets, in mice induced by streptozotocin.
Risk Factor Profile and Role of Cardiovascular Disease Outreach Program by Experts in Rural Communities: A Pilot Study in Magetan Regency, Indonesia Wungu, Citrawati Dyah Kencono; Elvaretta, Clarissa; Palupi, Dian Eka Roro; Qurnianingsih, Ema; Susilo, Hendri; Lukitasari, Lina; Humairah, Ira; Khaerunnisa, Siti; Soetjipto, Soetjipto; Handajani, Retno; Safitri, Indri; Ummah, Fithriyah Cholifatul; Waskito, Langgeng Agung; Prabowo, Gwenny Ichsan; Wiratama, Bayu Satria; Amin, Indah Binti Mohd
Jurnal Keperawatan Soedirman Vol 19 No 2 (2024): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2024.19.2.10947

Abstract

Cardiovascular outreach programs and risk factors profiling have been regarded as key strategy in preventing and controlling cardiovascular diseases as the leading global causes of death worldwide, especially when being conducted by a professional. This pilot study aims to evaluate the effectiveness of a cardiovascular outreach program in Plaosan District, Magetan Regency, to improve knowledge and influence changes in the community’s behavior related to cardiovascular risk factors. This study was conducted by providing educational interventions and profiling cardiovascular risk factors on 90 adults using consecutive sampling method. Health education was performed by experts and evaluated by pre-post tests before and after the material delivery. Statistical analysis was used to assess the relationship of risk factors that can contribute to cardiovascular disease. This study showed a significant increase in the participants' knowledge score after the intervention (p = 0.007). There were several risk factors for cardiovascular disease in the participants, with the highest risk prevalence being diabetes mellitus (33.33%). Six participants (6.67%) had abnormal electrocardiography results. In conclusion, our study showed a high prevalence of cardiovascular risk factors in rural communities and the importance of cardiovascular outreach programs by experts to improve the understanding of cardiovascular disease in a specific community.
Peningkatan pengetahuan untuk pencegahan stunting melalui sosialisasi dan demo pembuatan makanan balita berbahan dasar protein hewani bagi kelompok istri peternak sapi pedaging rumahan di Desa Lando, Lombok Timur, Nusa Tenggara Barat [Increasing knowledge for stunting prevention through socialization and demonstration for creating animal protein-based toddler food for a group of wives of home-based beef cattle farmers in Lando Village, East Lombok, West Nusa Tenggara] Qurnianingsih, Ema Ema; Rusyda, Aqila sabila; Hamzah, Arshq Mirza; Rachmawati, Kadek; Humairah, Ira Ira; Lukitasari, Lina; Khaerunnisa, St; Wungu, Citrawati Dyah Kencono; Ummah, Fithriyah Cholifatul Ummah; Kholik, Kholik; Riwu, Katty Hendriana Priscilia; Pradana, Munawer; Yansri, Alifianita Anake; Hidayat, Muhammad; Prabowo, Gwenny Ichsan
Buletin Pengabdian Vol 4, No 3 (2024): Bull. Community. Serv.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/bulpen.v4i3.40293

Abstract

Stunting is a condition of failure to thrive in children under five (toddlers) which can hinder the child's physical and mental development. Data from the 2023 Indonesian Health Survey (SKI) shows that the number of stunted toddlers in West Nusa Tenggara (NTB) Province is still quite high, namely 24.6%. Stunting cannot be cured but can be prevented. One of the prevention efforts is to increase the knowledge of mothers or prospective mothers regarding stunting and preventing it by providing food with high nutrition. This Community Service Activity (PKM) was carried out with the aim of educating mothers and wives of home-based beef cattle farmers in Lando Village, East Lombok, NTB about preventing stunting by providing highly nutritious supplementary food (PMT) and stunting detection. The methods used were socialization and demonstration of making toddler food. The results of this PKM activity were that there was a significant increase in participants' knowledge regarding the material being socialized (p0.0001). The conclusion that can be drawn is that There had been an increase in knowledge among PKM participants regarding stunting and preventing stunting through providing food with high protein content.
Integrating FIB-4 and APRI into Clinical Practice Guidelines: A Literature Review Ghaniyya, Willandra Fitriyanri; Humairah , Ira; Kholili , Ulfa
Scientica: Jurnal Ilmiah Sains dan Teknologi Vol. 3 No. 2 (2024): Scientica: Jurnal Ilmiah Sains dan Teknologi
Publisher : Komunitas Menulis dan Meneliti (Kolibi)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The FIB-4 and APRI indices have emerged as pivotal tools in the non-invasive assessment of liver fibrosis and cirrhosis, providing clinicians with accessible and cost-effective alternatives to liver biopsy. These scoring systems utilize routine laboratory parameters to stratify patients based on their risk of advanced fibrosis, making them especially valuable in managing chronic hepatitis B (HBV), hepatitis C (HCV), and non-alcoholic fatty liver disease (NAFLD). Their integration into clinical practice has significantly improved diagnostic accuracy and reduced the burden of invasive procedures, particularly in resource-constrained settings. Despite their advantages, the global adoption of FIB-4 and APRI faces several barriers. Variability in healthcare infrastructure, access to diagnostic resources, and differences in patient populations pose challenges to their consistent implementation. Furthermore, inequality in healthcare delivery systems and a lack of standardized protocols can lead to inconsistent utilization, particularly in low- to middle-income countries. Addressing these obstacles is critical to ensuring equitable and reliable liver disease assessment across diverse healthcare systems. Future research should focus on refining these indices, exploring their performance in diverse populations, and integrating them with emerging diagnostic technologies. Policymakers and healthcare stakeholders must work collaboratively to develop adaptable clinical guidelines that incorporate non-invasive liver tests into routine practice. By overcoming these challenges, the global integration of FIB-4 and APRI has the potential to transform liver disease management, improve patient outcomes, and promote health equity worldwide.
Dyslipidemia is Associated with Coronary Heart Disease in Patients with Type 2 Diabetes Mellitus at a Tertiary Hospital in Surabaya, Indonesia Ramadhani, Rizqi Nabila; Humairah, Ira; Novida, Hermina; Qurnianingsih, Ema
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 1 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i1.64560

Abstract

Introduction: Diabetes mellitus ranks as the third leading cause of mortality in Indonesia. The commonly found comorbidity of diabetes mellitus is cardiovascular disease, which contributes to elevated mortality rates. Diabetes mellitus sufferers face a heightened risk of cardiovascular disease, in part, due to dyslipidemia. This study aimed to establish the association between dyslipidemia and coronary heart disease (CHD) in type 2 diabetes mellitus (T2DM) patients receiving treatment at the diabetes subdivision of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Methods: This retrospective cross-sectional investigation examined 100 eligible individuals with T2DM and dyslipidemia at the diabetes subdivision of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, to assess the prevalence of CHD. Statistical analysis was performed using Pearson's chi-squared test to determine whether there was an association between dyslipidemia and CHD in the T2DM sufferers. If the p-value was below 0.05, the findings of the analysis were considered significant. The statistical test was conducted through IBM SPSS Statistics for Windows, version 26.0 (IBM Corp., Armonk, N.Y., USA). Results: Dyslipidemia was present in 74% of the T2DM patients. Patients who had dyslipidemia and T2DM were primarily female and aged between 51 and 60 years. Meanwhile, CHD affected 40 T2DM patients (40%). These patients were predominantly male and between the ages of 51 and 60. T2DM patients who also suffered from CHD typically presented with dyslipidemia (85%). Conclusion: This study demonstrates that the presence of dyslipidemia in T2DM sufferers is associated with CHD.   Highlights: 1. This study examined type 2 diabetes mellitus patients receiving treatment in a tertiary hospital to determine the association between dyslipidemia and coronary heart disease, an important concern given the rising prevalence of the disease in Indonesia. 2. The analysis revealed that type 2 diabetes mellitus patients who also have dyslipidemia face an elevated risk of developing coronary heart disease. 3. This study offers additional information, particularly related to the presence of dyslipidemia and coronary heart disease, which may enhance the management of type 2 diabetes mellitus throughout primary, secondary, and tertiary health facilities.
Pendampingan Kegiatan Pemberian Makanan Tambahan (PMT) di TK Negeri 01 Loa Janan Melalui Program Kerja Mahasiswa KKN Humairah, Ira; Alfian, Adit Alfian; Septiyani, Michaelia; Putri, Anis Natasya; Salsabila, Annisa Aulia; Sabir, Rafni Nuranda; Muhtar, Muhtar
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 6 No. 2 (2025): Jurnal Pengabdian kepada Masyarakat Nusantara Edisi April - Juni
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v6i2.5870

Abstract

Kegiatan pemberian makanan tambahan (PMT) merupakan salah satu upaya untuk meningkatkan status gizi anak usia dini guna mendukung pertumbuhan dan perkembangan yang optimal. Program Kuliah Kerja Nyata (KKN) menjadi wadah bagi mahasiswa untuk berkontribusi dalam mendampingi pelaksanaan PMT di TK Negeri 01 Loa Janan Desa Tani Harapan. Kegiatan ini bertujuan untuk meningkatkan pemahaman guru dan orang tua terkait pentingnya gizi seimbang serta memastikan keberlanjutan program PMT di lingkungan sekolah. Metode yang digunakan meliputi edukasi gizi, pendampingan penyusunan menu PMT, serta praktik langsung dalam penyajian makanan bergizi. Hasil kegiatan menunjukkan adanya peningkatan kesadaran dan keterampilan guru serta orang tua dalam menyediakan makanan sehat bagi anak-anak. Selain itu, program ini juga mendapatkan respons positif dari pihak sekolah dan masyarakat, sehingga diharapkan dapat menjadi model bagi pelaksanaan PMT di sekolah lainnya.
Co-Authors . Kholik Alfian, Adit Alfian Amin, Indah Binti Mohd Arna, Nadhifa Artaria Tjempakasari, Artaria Atika Atika Ayesie Natasha Zulka Bakhtiar, Arief Bayu Satria Wiratama Claudia Clary Navisa Elvaretta, Clarissa Ely Rahmatika Nugrahani Ghaniyya, Willandra Fitriyanri Ginanjar Sasmito Adi Gwenny IP Hamzah, Arshq Mirza Harianto Notopuro Hendri Susilo HERAWATI, LILIK Hermina Novida, Hermina Indri Safitri Indri Safitri, Indri Joni Susanto, Joni Kadek Rachmawati Khaerunnisa, Siti Lauric, Kelsey Lukitasari, Lina Mahindisyah, Muhammad Ghifary Manik, Andrea Valerie Muhammad Hidayat Muhammad Rifqi Adinagoro Muhtar Muhtar Palupi, Dian Eka Roro Prabowo, Gwenny Ichsan Pradana, Munawer Putri, Anis Natasya Qurnianingsih, Ema Ramadhani, Rizqi Nabila Retno Handajani Reza Arta BN Ridhwan Biosia Wiratama Riwu, Katty Hendriana Priscilia Rusyda, Aqila sabila Sabir, Rafni Nuranda Salsabila, Annisa Aulia Septiyani, Michaelia Siti Khaerunnisa Siti Khaerunnisa SOETJIPTO . Suhartati Suhartati Suhartati Susi Wahyuning Asih Sutji Kuswarini Suwandito Suwandito Syafa’ah, Irmi Ulfa Kholili Ummah, Fithriyah Cholifatul Ummah, Fithriyah Cholifatul Ummah Waskito, Langgeng Agung Wungu, Citrawati Dyah Kencono Yohanes Widyakusuma E.S Yuliawati, Tri Hartini Zuhrotul Eka Yulis Anggraeni