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Mung Bean Sprouts (Vigna radiata) Ethanol Extract on Alanine Aminotransferase (ALT) Activity and Malondialdehyde (MDA) Levels in Toluene-Induced Rats Putu Bayu Agus S.Si; Siti Khaerunnisa M.Si; Lina Lukitasari, M.Si
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17607

Abstract

Objective –This study aimed to evaluate the effect ofethanol extract from mung bean sprouts on alanine aminotransferase (ALT) activity and malondialdehyde levels in toluene-induced white rats.Methods–This research is an experimental laboratory with a research design that is post-test only control group design using 40 rats (Rattus norvegicus) which were divided randomly into 5 groups, G1 (control without toluene), G2 (900 mg/kg toluene), G3 (mung bean sprouts extract 250 mg/kg + 900 mg/kg toluene), G4 (mung bean sprouts extract 500 mg/kg + 900 mg/kg toluene), G5 (mung bean sprouts extract 1000 mg/kg + 900 mg/kg toluene). ALT measurement using spectrophotometer method. Measurement of MDA using the ELISA method. The data collected will be statistically tested with the help of SPSS with a significant (p <0.05).Results–The results of the measurement of ALT activity (p=0.972) and MDA levels (p=0.190) in each group had no significant effect (p>0.05) in each treatment.Conclusion–It can be concluded that there was no significant effect of ethanol extract of sprouts on alanine aminotransferase (ALT) activity and malondialdehyde levels in white rats (Rattus norvegicus) induced by oral toluene.
Prevention and Early Detection of Metabolic Syndrome in Household Community, Surabaya Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Siti Khaerunnisa; Gwenny Ichsan Prabowo; Suhartati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15747

Abstract

Introduction. Metabolic syndrome is a collection of factors believed to increase the risk of atherosclerosis and type 2 diabetes mellitus. The incidence of metabolic syndrome in young adults is increasing, especially in Asian countries. Therefore we need efforts to increase knowledge in society about this disease. Aim. We conducted a socialization program on prevention and early detection of metabolic syndrome in household community to increase public knowledge about this disease.Method. This program was conducted in August 2017 in Wonokromo District, Surabaya. The participants in the activity consisted of 32 people from household community. The activity consisted of blood sampling collection, body weight, and abdominal circumference measurement for risk factor assessment, pre-test, socialization of metabolic syndrome, and post-test.Results. From the results of the pre and post test, we found an increase knowledge of 76.9% participants. The laboratory test results for early detection of metabolic syndrome showed 37.5% of participants had metabolic syndrome. We also found a significant positive correlation between body weight and abdominal circumference (p = 0.000, r = 0.867). There was also a significant negative correlation between body weight and HDL (p = 0.004, r = -0.494), between abdominal circumference and HDL (p <0.05, r = -0.376), and between TG and HDL (p <0.05, r = -4.22).Conclusion. Socialization and early detection of metabolic syndrome can increase knowledge, awareness, and detection of metabolic syndrome in the household community.
The Improvement of Community Knowledge, Attitudes and Practices After Covid-19 Socialization Siti Khaerunnisa; Irmi Syafa'ah; Citrawati Dyah Kencono Wungu; Gwenny Ichsan Prabowo; Retno Handajani; Indri Safitri; Harianto Notopuro; Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Arief Bakhtiar; Suwandito Suwandito; Susi Wahyuning Asih; Zuhrotul Eka Yulis Anggraeni; Ginanjar Sasmito Adi; Ely Rahmatika Nugrahani; Ayesie Natasha Zulka; Soetjipto Soetjipto
Folia Medica Indonesiana Vol. 57 No. 2 (2021): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.653 KB) | DOI: 10.20473/fmi.v57i2.26262

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This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low attitude, very high practice, high practice, sufficient practice, and low practice were 58.33 ± 30.97, 77.70 ± 22.52, 62.5±21.7, 31±22.2, 6.5±17.1, 65±13.8, 32.3±13.8, 1.25±2.4, 1.25±1.8, respectively. Knowledge pre-test and post-test correlated 0.819 (p=0.001) and a t-test with p=0.003. Attitudes and practices correlated with p=0.001. Socialization of COVID-19 was useful to improve the community knowledge, attitudes, and practices in Rambipuji and Suci Village, Jember District, East Java, Indonesia that could prevent the transmission and inhibit the spread of the COVID-19 pandemic in Indonesia. Furthermore, continuous encouragement of COVID-19 socialization in wide areas was recommended.
High Calorie Diet with a Combination of Intermittent Restriction Affects the Reproductive Cycle and The Uterine Weight of Mice (Mus Musculus) Anggraeni Dyah Kumalasari; Lilik Herawati; Raden Argarini; Lina Lukitasari; Zulhabri Othman; Astika Gita Ningrum
Folia Medica Indonesiana Vol. 57 No. 4 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (812.554 KB) | DOI: 10.20473/fmi.v57i4.29115

Abstract

Highlight:High-calorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice were analyzed.Calories balance impact for female reproductive health. Abstract :Balanced calories affected for body health and daily activities. Lose of energy can disturb the health and daily activities, while over calorie for diets also causes disorders such as metabolic. When there are excess calories in the body will be involved. It can be an obesity risk, diabetes mellitus, fertility disorder, cancer, and cardiovascular disease. Furthermore, in women there can be an increase in menstrual disorders and fertility disorder risk (Silvestris et al., 2018). This study aims to analyze highcalorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice. Experimental laboratory is a mouse (mus musculus) female’s balb/c as object population. Sampling techniques using probability sampling with simple random sampling type. The study results on fisher's exact test gave a result of p > 0.05 so there was no significant difference between control group, high calorie diet group, and high calorie diet with interval restrictions group on the results of vaginal swabs /post-treatment reproductive cycle. The study outcome on robust tests between control, high calorie diet, and high calorie diet with interval restrictions groups. Obtained results (p < 0.05) that mean there are some significant discrepancies in the weight of uterine organ between groups. Calories balance in the body can impact female reproductive health.
APRI Profile of Cirrhotic Patients with Positive HBsAg Nadya Husni; Leonita Anniwati; Lina Lukitasari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.482 KB) | DOI: 10.20473/juxta.V10I12019.34-37

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Introduction: Hepatitis B is a viral infection that has the potency to become chronic infection and cause serious complications such as liver cirrhosis and hepatocellular carcinoma. One of the tools in diagnosing hepatitis B or cirrhosis and predicting the prognosis is aspartate aminotransferase to platelet ratio index (APRI). The purpose of this study is to evaluate the profile of APRI among cirrhotic patients with positive hepatitis B surface antigen (HBsAg).Method: This research was a descriptive observational study. The number of samples was 35 cirrhotic patients with positive HBsAg in RSUD Dr. Soetomo Surabaya from January-December 2017.Results: The majority of cirrhotic patients had >1,5 APRI score (48,57%). The most prevalent APRI score in Child A patients for first classification was 0,5 – 1,5 (5,71%) while for second classification was 0,7 – 1,5 (5,71%). The most prevalent APRI score in Child B patients for first classification was 0,5 – 1,5 (17,14%) while for second classification was 0,7 – 1,5 (11,43%). Most of Child C patients had >1,5 APRI score (22,86%). The majority of malignant degeneration patients also had >1,5 APRI score (14,29%).Conclusion: The majority of cirrhotic patients had >1,5 APRI score. In cirrhotic patients with Child A or B classification, the increase of APRI score was not as much as those with Child C or malignant degeneration classification.Keywords: Hepatitis B, cirrhosis, liver, hepatocellular carcinoma, APRI
SARI ETANOL, ETIL ASETAT ALANG-ALANG (IMPERATA CYLINDRICA) TERHADAP SUPEROXIDE DISMUTASE (SOD) St Khaerunnisa; Sutji Kuswarini; Suhartati Suhartati; Lina Lukitasari; Ira Humairah; Reza Arta BN; Gwenny IP
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 2 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i2.1080

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Oxidative stress has been considered as a mechanism involved in the pathogenesis and progression of many diseases such as:hypercholesterolemia and atherosclerosis. The objective of this current study was to know the potential antioxidant role of ethanol andethyl acetate extract of reeds (Imperata cylindrica) by investigation in rats fed with a high-cholesterol diet. Imperata cylindrica is richin antioxidants and has a cholesterol-reducing effect. A group of twenty four male albino Wistar rats was divided into four subgroups: anormal diet group (K0), a high-cholesterol diet group (K1), the same diet with ethanol extract of Imperata cylindrica group (K2), and thesimilar diet with ethyl acetate fraction of Imperata cylindrica group (K3),. After the treatment period, the hepatic antioxidant enzymeactivity (Superoxide dismutase/SOD) was determined. The rats fed on high-cholesterol diet with supplementation exhibited a significantelevation in SOD activity (p<0. 05), 61.6±12.4% inhibition, compared to normal animals 37.44±12.2%. The treated animals withethanol and ethyl acetate extract of Imperata cylindrica showed a significantly reduced the level of SOD activity (p<0.05, 29.90±5.6%as well as a 33.49±7.4% inhibition). The level of SOD activity when restored was closer to that in normal animals, signifying reversalof the oxidative stress. The study results showed that the treatment with Imperata cylindrica positively changed the hepatic antioxidantenzyme activities in high fat-diet rats, and thus had potential hypocholesterolemic and antioxidant effects. Imperata cylindrica couldprotect against oxidative stress linked to atherosclerosis and also decrease the atherogenic index.
PENGARUH PELAKASANAAN PROGRAM KESEJAHTERAAN JAMINAN SOSIAL, INSENTIF DAN PELATIHAN KERJA TERHADAP PRODUKTIVITAS KARYAWAN CV. IJO GENENG NGAWI Lina Lukitasari
FIPA : Forum Ilmiah Pendidikan Akuntansi Vol 3, No 1 (2015): FIPA 5
Publisher : FIPA : Forum Ilmiah Pendidikan Akuntansi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.912 KB)

Abstract

Produktivitas suatu perusahaan menggambarkan kinerja yang ada didalam sebuah perusahaan, dan mencerminkan berhasil tidaknya sistem kerja didalam menghasilkan output berupa barang atau jasa. Penelitian ini bertujuan untuk menguji pengaruh jaminan sosial, insentif dan pelatihan kerja secara parsial dan silmutan terhadap produktivitas karyawan pada CV. IJO Geneng Ngawi.    Populasi dalam penelitian ini adalah seluruh karyawan bagian produksi CV. IJO Geneng Ngawi, yaitu sebanyak 45 karyawan. Teknik pengambilan sampel dilakukan dengan sampling jenuh sehingga jumlah sampel yang diperoleh sebanyak 33 karyawan bagian produksi. Teknik pengumpulan data dilakukan dengan menggunakan kuesioner, observasi dan wawancara. Metode analisis yang digunakan adalah regresi linier berganda. Hasil penelitian ini menunjukkan bahwa jaminan sosial, insentif dan pelatihan kerja berpengaruh signifikan secara simultan terhadap produktivitas karyawan. Secara parsial jaminan sosial tidak berpengaruh signifikan terhadap produktivitas karyawan. Sedangkan insentif dan pelatihan kerja berpengaruh positif dan signifikan terhadap produktivitas karyawan.  Kata Kunci : Produktivitas Karyawan, Jaminan Sosial, Insentif, Pelatihan Kerja.
Effect of Short-Term Extra Maltodextrin during a Diet Break on the Resistance Training Performance of Rattus norvegicus Muhammad Irfan Indiarto; Irfiansyah Irwadi; Lina Lukitasari; Atika
Folia Medica Indonesiana Vol. 59 No. 4 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v59i4.39677

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Highlights: 1. The ongoing advancement of dietary research has significant importance in the exploration of strategies to optimize the impact of nutrition on performance during resistance training.2. This study provides a prompt for future research to explore the effectiveness of incorporating an additional dietary strategy that may enhance resistance training performance.   Abstract: Poor diet with a purpose to lose a certain body weight or body fat can impair muscle protein synthesis. This results in muscle loss and poor performance in physical training, particularly resistance training. This study aimed to determine the short-term effect of extra carbohydrates, specifically in the form of maltodextrin, during a diet break on the resistance training performanced by rats. This study was an experimental laboratory study with a randomized posttest-only control group design. Twenty-seven male rats, aged 3 months with a weight range of 140–165 g, were randomly and equally assigned into three groups: KN (standard diet), KP (75% calorie intake), and K1 (65% calorie intake with a diet break and extra maltodextrin every week). These diets were administered for four weeks, during which the rats had ad libitum feeding. Additionally, the rats underwent ladder-climbing training three times a week. The body weight was measured pre- and post-treatment, while the performance in resistance training was evaluated post-intervention using a ladder climbing platform. There was no significant difference in the weight before and after treatment, with p>0.05 for the increments (∆) among KN (14.00±9.89 g), KP (13±9.5 g), and K1 (20.89±14.77 g). According to the posttest assessment results, only 17 out of 27 rats succeeded in the maximum weightlifting test. This study showed that a short-term high-carbohydrate diet break does not improve the resistance training performance of rats. Further research is necessary to ascertain the outcomes of the treatment implemented over an extended period of time. 
Risk Factor Profile and Role of Cardiovascular Disease Outreach Program by Experts in Rural Communities: A Pilot Study in Magetan Regency, Indonesia Wungu, Citrawati Dyah Kencono; Elvaretta, Clarissa; Palupi, Dian Eka Roro; Qurnianingsih, Ema; Susilo, Hendri; Lukitasari, Lina; Humairah, Ira; Khaerunnisa, Siti; Soetjipto, Soetjipto; Handajani, Retno; Safitri, Indri; Ummah, Fithriyah Cholifatul; Waskito, Langgeng Agung; Prabowo, Gwenny Ichsan; Wiratama, Bayu Satria; Amin, Indah Binti Mohd
Jurnal Keperawatan Soedirman Vol 19 No 2 (2024): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2024.19.2.10947

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Cardiovascular outreach programs and risk factors profiling have been regarded as key strategy in preventing and controlling cardiovascular diseases as the leading global causes of death worldwide, especially when being conducted by a professional. This pilot study aims to evaluate the effectiveness of a cardiovascular outreach program in Plaosan District, Magetan Regency, to improve knowledge and influence changes in the community’s behavior related to cardiovascular risk factors. This study was conducted by providing educational interventions and profiling cardiovascular risk factors on 90 adults using consecutive sampling method. Health education was performed by experts and evaluated by pre-post tests before and after the material delivery. Statistical analysis was used to assess the relationship of risk factors that can contribute to cardiovascular disease. This study showed a significant increase in the participants' knowledge score after the intervention (p = 0.007). There were several risk factors for cardiovascular disease in the participants, with the highest risk prevalence being diabetes mellitus (33.33%). Six participants (6.67%) had abnormal electrocardiography results. In conclusion, our study showed a high prevalence of cardiovascular risk factors in rural communities and the importance of cardiovascular outreach programs by experts to improve the understanding of cardiovascular disease in a specific community.
Peningkatan pengetahuan untuk pencegahan stunting melalui sosialisasi dan demo pembuatan makanan balita berbahan dasar protein hewani bagi kelompok istri peternak sapi pedaging rumahan di Desa Lando, Lombok Timur, Nusa Tenggara Barat [Increasing knowledge for stunting prevention through socialization and demonstration for creating animal protein-based toddler food for a group of wives of home-based beef cattle farmers in Lando Village, East Lombok, West Nusa Tenggara] Qurnianingsih, Ema Ema; Rusyda, Aqila sabila; Hamzah, Arshq Mirza; Rachmawati, Kadek; Humairah, Ira Ira; Lukitasari, Lina; Khaerunnisa, St; Wungu, Citrawati Dyah Kencono; Ummah, Fithriyah Cholifatul Ummah; Kholik, Kholik; Riwu, Katty Hendriana Priscilia; Pradana, Munawer; Yansri, Alifianita Anake; Hidayat, Muhammad; Prabowo, Gwenny Ichsan
Buletin Pengabdian Vol 4, No 3 (2024): Bull. Community. Serv.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/bulpen.v4i3.40293

Abstract

Stunting is a condition of failure to thrive in children under five (toddlers) which can hinder the child's physical and mental development. Data from the 2023 Indonesian Health Survey (SKI) shows that the number of stunted toddlers in West Nusa Tenggara (NTB) Province is still quite high, namely 24.6%. Stunting cannot be cured but can be prevented. One of the prevention efforts is to increase the knowledge of mothers or prospective mothers regarding stunting and preventing it by providing food with high nutrition. This Community Service Activity (PKM) was carried out with the aim of educating mothers and wives of home-based beef cattle farmers in Lando Village, East Lombok, NTB about preventing stunting by providing highly nutritious supplementary food (PMT) and stunting detection. The methods used were socialization and demonstration of making toddler food. The results of this PKM activity were that there was a significant increase in participants' knowledge regarding the material being socialized (p0.0001). The conclusion that can be drawn is that There had been an increase in knowledge among PKM participants regarding stunting and preventing stunting through providing food with high protein content.