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All Journal International Journal of Health and Pharmaceutical (IJHP)
Nyoman Ehrich Lister, I
Unknown Affiliation
Nursing Public Health

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Antiaging Cream Formula From Lemongrass Leaf Extract (Chymbopogon Citratus) Ramadhani, Shafira; Nyoman Ehrich Lister, I; Fachrial, Edy; Hakim Nasution, Ikhwanul
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 4 (2023): November 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i4.222

Abstract

This study aimed to determine the formula of anti-aging cream using lemongrass leaf extract. The treatment by giving respondents lemongrass leaf extract and using moisture, evenness, pore, spot, and wrinkle as parameters. Human skin provides protection on the surface of the body against the influence of the surrounding environment. Skin can experience aging, especially in areas that are often exposed to direct sunlight such as the face, neck, upper arms, and hands. Aging is a process experienced by humans in their 30s whose functions in the human body are decreasing, for example, thinning skin, wrinkles, rough skin, and dark spots on the face. Treatment to prevent aging of the skin by using an antioxidant product such as flavonoids because it has the function of preventing or neutralizing free radicals. In Indonesia, several species of plants can be found that function as food and cosmetic ingredients. The lemongrass leaf extract which contains antiaging are Alkaloids, Flavonoids, and Tannins. The data were analysed by using the Kolmogorov-Smirnov method to determine homogeneity and normality. Then, if the data is normal, it is continued to be analysed using the One-Way ANOVA method to determine the average difference between groups. There is a difference between treatments, and it is continued with the Post-hoc Tukey HSD test. The higher the concentration of extract used, the greater the anti-aging productivity formed. It is concluded, the best anti-aging effect is a concentration of 9% with increase in moisture, evenness, pore reduction, reducing spots and wrinkles.
Anti-Diabetic Effect of Snake Fruit Skin Extract in Alloxan-Induced Wistar Rat Marzuki, Marlinda; Girsang, Ermi; Napiah Nasution, Ali; Nyoman Ehrich Lister, I
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.251 KB) | DOI: 10.51601/ijhp.v3i1.143

Abstract

Basic Health Research Report shows that an average prevalence of diabetes mellitus (DM) in urban areas is 5.7% in the population aged over 15 years. Many studies have been conducted to explore the pharmacological effects of snake fruit skin as different preparations against DM. In this study, the effect of snake fruit skin extract (SFSE) on body weight and blood glucose levels induced by alloxan was tested on 25 male Wistar rats. All rats were initially induced with 5% alloxan (150 mg/kg BW) then after 48 hours were grouped into: control (Na-CMC 0.5%), standard (Metformin), SFSE-I (60 mg/200 gBW), SFSE -II (120 mg/200 gBW), and SFSE-III (240 mg/200 gBW). The treatment was given for 14 days. The results showed that the tendency for the highest blood glucose levels of about 333 mg/dl (after 28 days of treatment) was found in the control group, followed by SFSE-I (222 mg/dl), -II (205 mg/dl), -III (138 mg/dl), and the lowest in the standard group was about 129 mg/dl. Hence, it can be concluded that SFSE which has the best antihyperglycemic effect was obtained with the highest dose of 240 mg/200 gBW.
Co-Authors Edy Fachrial Girsang, Ermi Hakim Nasution, Ikhwanul Marzuki, Marlinda Napiah Nasution, Ali Ramadhani, Shafira