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All Journal Jurnal Ilmiah Farmako Bahari Praeparandi : Jurnal Farmasi dan Sains Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia
Mardhiyyah, Cut Ainul
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology

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ANALISIS FAKTOR RESIKO KEMATIAN DENGAN KOMORBID PASIEN COVID-19 DI RUMAH SAKIT PERMATA CIREBON Mardhiyyah, Cut Ainul; Septiansyah, Luky; Mundzir, O. Ahmad; Karsidin, Bambang; Pandanwangi, Siti; Utami, Amanda Dwi
Praeparandi : Jurnal Farmasi dan Sains Vol 6 No 1 (2022): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Praeparandi : Jurnal Farmasi dan Sains

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.096 KB) | DOI: 10.58365/ojs.v6i1.187

Abstract

Penyakit coronavirus 2019 (COVID-19) menimbulkan perhatian kesehatan yang besar saat ini, terutama untuk lanjut usia. Wabah pneumonia virus yang tidak diketahui dengan etiologinya pertama kali diperkenalkan di Wuhan, Cina pada 12 Desember 2019. Orang-orang dengan penyakit komorbid lebih beresiko menderita gejala yang parah apabila terkena virus corona. Penelitian ini bersifat deskriptif dengan menggunakan data retrospektif. Jumlah sampel yang memenuhi kriteria inklusi dan tidak memenuhi kriteria eksklusi sebesar 200 orang. Penelitian ini bertujuan untuk mengetahui karakteristik data demografi usia dan jenis kelamin pada komorbid pasien COVID-19 dan dapat menganalisis faktor resiko kasus terkonfirmasi COVID-19 dengan komorbid di Rumah Sakit Permata Cirebon. Hasil data demografi jenis kelamin pada pasien COVID-19 didominasi oleh laki-laki 1,93 kali dari jenis kelamin perempuan, data demografi usia pada pasien COVID-19 didominasi oleh kelompok usia kurang dari 60 tahun sebanyak 4,38 kali dari kelompok usia lebih dari 60 tahun, sedangkan faktor komorbid COVID-19 yang paling banyak adalah Penyakit Jantung yaitu 1,050 kali dari komorbid lainnya yaitu hipertensi, diabetes melitus, dan penyakit ginjal.
Penggunaan Deksametason pada Pasien COVID-19: Systematic Review dan Meta-analisis Mardhiyyah, Cut Ainul; Setiawan, Didik; Dhiani, Binar Asrining
Jurnal Kefarmasian Indonesia VOLUME 13, NOMOR 1, FEBRUARI 2023
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v13i1.5455

Abstract

COVID-19 is associated with disseminated lung damage in patients, Dexamethasone can reduce lung injury caused by inflammation and there reduce the progression to respiratory failure and prevent death. This systematic review aimed to determine the benefits and safety of Dexamethasone in COVID-19 treatment. The study was performed by a comprehensive literature search which were published in several databases i.e., PubMed, Science Direct, VHL Regional Portal, and ClinicalTrials.gov within the search time of 28 November 2020. Inclusion criteria were articles on the study on COVID-19 patients who received Dexamethasone, observational and experimental studies on the outcomes use evaluation of Dexamethasone. Exclusion criteria are the articles that do not provide control in controlled studies and do not show clear research results on the use of Dexamethasone. An initial search from four databases by entering keywords resulted in 1,046 articles. After screening articles duplication we obtained 835 studies. Finally, 6 articles were obtained after we screened for the article that it can be obtained its full text and 5 articles joined in articles included in the meta-analysis. The analysis showed that Dexamethasone in Covid-19 patients could reduce the incidence of death within 28 days with RR of 0.78 (95% CI 0.57–0.97 P=0.13) compared with Methylprednisolone, Dexamethasone was compared without corticosteroids with RR 0.89 (95% CI 0.82-0.97 P=0.01). Dexamethasone also reduced mechanical ventilator use during treatment with RR 0.95 (95% CI = 0.86-1.05 P = 0.28) compared without corticosteroids. The conclusion from these results: the use of Dexamethasone can reduce the number of deaths in COVID-19 patients, especially severe and critically ill category patients.
CORRELATION OF COMMUNITY PHARMACIST KNOWLEDGE, ATTITUDES, AND PRACTICES IN THE DETECTION OF TUBERCULOSIS CASES IN WEST JAVA PROVINCE Mardhiyyah, Cut Ainul; Zuniarto, Ahmad Azrul; Amanatin, Alfitia Dwi; Ryansyah, Hardi; Antonia, Vonny
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1296

Abstract

Tuberculosis (TB) control is hampered by suboptimal case detection and treatment delays. Pharmacies are reported as a first-aid treatment for patients with TB. Therefore, researchers analyzed knowledge, attitudes, and practices (KAP) regarding TB case detection among community pharmacists, aiming to find innovative strategies to involve community pharmacists in TB case detection. The research aims to determine the level of knowledge, attitudes, and practices, and the relationship between knowledge and attitude, knowledge-practice, and attitude-practice of community pharmacists in detecting tuberculosis cases in West Java Province. This research uses a descriptive observational method with 419 pharmacists who practice pharmacies. The results showed that pharmacists had a sufficient level of knowledge (14.94 ± 1.99), an adequate level of attitude (63.58 ± 9.12), and a sufficient level of practice (20.58 ± 8.55) regarding TB case detection. There is a very low relationship between knowledge and attitude (p-value 0.024<0.05), knowledge and practice ( p-value 0.018>0.05), and attitude and practice ( p-value 0.000< 0.05). This study concluded that community pharmacists in West Java Province have sufficient knowledge, attitudes, and practices in detecting TB cases, but the level of relationship between knowledge attitude and detecting TB cases, and the level of association between knowledge attitude and knowledge practice was very low, while the relationship between attitude practice was low. Keywords: Pharmacist, Knowledge, Practice, Attitude, Tuberculosis
Pengetahuan, Sikap, dan Praktik Apoteker Komunitas dalam Pemantauan Pengobatan Pasien Tuberkulosis di Provinsi dengan Prevalensi Tuberkulosis Tinggi di Indonesia Mardhiyyah, Cut Ainul; Zuniarto, Ahmad Azrul; Ryansyah, Hardi; Amanatin, Alfitia Dwi; Antonia, Vonny; Sumari, Sumari
Jurnal Ilmiah Farmako Bahari Vol 16 No 2 (2025): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v16i2.42294

Abstract

Indonesia ranks second globally in tuberculosis (TB) cases, with West Java identified as a high-burden TB region. Community pharmacists, often the first point of patient contact, have the potential to support TB monitoring. However, their role remains underutilized and understudied. This study aimed to evaluate community pharmacists' knowledge, attitudes, and practices (KAP) in monitoring TB medication, and to examine the relationships among these variables and respondent characteristics. A cross-sectional study was conducted among 419 pharmacists across 27 districts and cities in West Java Province. Data were collected via a validated online questionnaire comprising KAP domains. Descriptive statistics, Spearman’s correlation, and Chi-Square tests were used to analyze relationships between KAP scores and demographic/professional characteristics. Community pharmacists demonstrated moderate knowledge in TB treatment (14.94 ± 1.99), generally have a positive attitude towards the importance of their role and ability to monitor use of TB drug (21.6 ± 3.3). In practice, community pharmacists are low in reporting, monitoring, and providing assistance related to TB patients (10.7 ± 5.2). Significant but low correlations were observed between knowledge and attitude (r = 0.110, p = 0.024), knowledge and practice (r = 0.116, p = 0.018), and attitude and practice (r = 0.343, p < 0.001). Practice scores were significantly associated with access to patient consultation services (p < 0.001), while knowledge was linked to pharmacy location (p = 0.032), and attitude to gender (p = 0.026). Although community pharmacists in West Java show sufficient knowledge and positive attitudes, their involvement in TB monitoring practices remains limited. Targeted education and policy interventions are essential for their engagement in national TB control efforts.
Co-Authors Amanatin, Alfitia Dwi Antonia, Vonny Binar Asrining Dhiani Didik Setiawan Karsidin, Bambang Mundzir, O. Ahmad Ryansyah, Hardi Septiansyah, Luky Siti Pandanwangi TW Sumari Sumari Utami, Amanda Dwi Zuniarto, Ahmad Azrul