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All Journal Jurnal Biologi Tropis Oto Rhino Laryngologica Indonesiana
Lubis, Yuliani M.
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Correlation of Tympanomastoidectomy Pathological Findings With Hearing Loss In Chronic Suppurative Otitis Media Patients Nasution, Nurhalimah; Zahara, Devira; Lubis, Yuliani M.; Harahap, Pahala Hanafi; Herwanto, H.R. Yusa; Ashar, Taufik
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.614

Abstract

Background: Patients with chronic suppurative otitis media (CSOM) often experience hearing loss from mild to very severe degrees. In addition, patients with CSOM often have intraoperative pathological findings. Aims of this study is to determine the correlation between intraoperative tympanomastoidectomy pathological findings with the type and degree of hearing loss using pure tone audiogram images in CSOM patients. Methods: This study is an analytic type study that uses a cross-sectional design. This research was conducted in three hospitals during October 2021 to December 2021. The sample size in this study was 37 patients who would undergo tympanomastodectomy surgery. Results: The most common pathological finding was granulation in 36 patients (97.3%) and followed by sclerotic in 31 patients (83.8%). The average patient had more than 2 pathological findings. Most of patients (78.4%) had conductive hearing loss and most of patients had moderate degree of hearing loss in 25 patients (67.6%). Based on type of hearing loss, there were significant associations with several pathological findings, namely cholesteatoma (p=0.003), defect ossicles (p=0.009), ossicular defects (p=0.001), facial nerve defects (p=0.009). In terms of the number of pathological findings, there was a significant correlation with hearing loss (p=0.004, r=0.467) and the degree of hearing loss (p=0.029, r=0.360). Conclusion: Among the pathological findings by type of hearing loss, a significant correlation was found.
Correlation Between Noise Levels and Noise-Induced Hearing Loss in Ground Handling Officers at Kualanamu Airport Putra, Aldi Maulana; Herwanto, Yusa; Lubis, Yuliani M.; Ashar, Taufik
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8867

Abstract

Airport ground handling officers are highly exposed to noise from aircraft operations, potentially leading to Noise-Induced Hearing Loss (NIHL). This study aims to investigate the correlation between noise levels and NIHL among ground handling officers at Kualanamu Airport. A cross-sectional observational design was applied. Data on noise levels were obtained using a sound level meter, and NIHL was assessed with a calibrated Interacoustics audiometer AD528. Among 23 officers exposed to 95 dB, 16 (69.6%) had NIHL, and among 5 officers exposed to 100 dB, 4 (80%) had NIHL. Statistical analysis using the Kruskal-Wallis test confirmed a significant relationship between noise levels and NIHL (p<0.001). The study highlights the need for preventive strategies in noisy airport environments. The conclusion is that there is a significant correlation between occupational noise exposure and the incidence of Noise Induced Hearing Loss (NIHL) among ground handling officers at Kualanamu International Airport.
Correlation of Tympanomastoidectomy Pathological Findings With Hearing Loss In Chronic Suppurative Otitis Media Patients Nasution, Nurhalimah; Zahara, Devira; Lubis, Yuliani M.; Harahap, Pahala Hanafi; Herwanto, H.R. Yusa; Ashar, Taufik
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.614

Abstract

Background: Patients with chronic suppurative otitis media (CSOM) often experience hearing loss from mild to very severe degrees. In addition, patients with CSOM often have intraoperative pathological findings. Aims of this study is to determine the correlation between intraoperative tympanomastoidectomy pathological findings with the type and degree of hearing loss using pure tone audiogram images in CSOM patients. Methods: This study is an analytic type study that uses a cross-sectional design. This research was conducted in three hospitals during October 2021 to December 2021. The sample size in this study was 37 patients who would undergo tympanomastodectomy surgery. Results: The most common pathological finding was granulation in 36 patients (97.3%) and followed by sclerotic in 31 patients (83.8%). The average patient had more than 2 pathological findings. Most of patients (78.4%) had conductive hearing loss and most of patients had moderate degree of hearing loss in 25 patients (67.6%). Based on type of hearing loss, there were significant associations with several pathological findings, namely cholesteatoma (p=0.003), defect ossicles (p=0.009), ossicular defects (p=0.001), facial nerve defects (p=0.009). In terms of the number of pathological findings, there was a significant correlation with hearing loss (p=0.004, r=0.467) and the degree of hearing loss (p=0.029, r=0.360). Conclusion: Among the pathological findings by type of hearing loss, a significant correlation was found.
Relationship Between Cigarette Smoke Exposure and Laryngeal Histopathology in Rattus novergicus Rats Nasution, Erizal Salam Putra; Herwanto, H. R. Yusa; Zahara, Devira; Aliandri, Aliandri; Lubis, Yuliani M.; Ashar, Taufik; Chrestella, Jessy
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10804

Abstract

Smoking can cause health problems for both active and passive smokers because the toxic substances contained in it cause health problems, especially in the larynx, one of which is laryngeal cancer. Animal studies have shown histopathological changes in mice exposed to cigarette smoke, including increased immune cells and focal inflammation in these mice. The study aims to determine the relationship between cigarette smoke and the number of inflammatory cells, edema, hyperplasia, and dysplasia after exposure to cigarette smoke for 120 minutes in histopathological sampling at observations of 0, 10, 20, 30 and 40 days. This study used a true experimental design model with a post-test only group laboratory experimental design. The results of the study found a significant difference in the number of lymphocytes before and after exposure to cigarette smoke with p = 0.043. There was no significant change in the number of macrophages with p = 0.406 and eosinophils with p = 0.119. There were no histopathological changes, namely edema (p = 0.06), dysplasia (p = 0.126) and hyperplasia (p = 0.960). In conclusion, there is a relationship between cigarette smoke exposure and laryngeal histopathology in Rattus novergicus Rats.
Co-Authors Aliandri, Aliandri Chrestella, Jessy Harahap, Pahala Hanafi Herwanto, H. R. Yusa Herwanto, R. Yusa Herwanto, Yusa Nasution, Erizal Salam Putra Nasution, Nurhalimah Putra, Aldi Maulana Taufik Ashar Zahara, Devira