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FAKTOR DETERMINAN PENCEGAHAN POTENSI PENULARAN TB PARU PADA KELUARGA DI WILAYAH KERJA PUSKESMAS KAR-TINI KOTA PEMATANG SIANTAR TAHUN 2023 Nasution, Erizal Salam Putra; Sarma, Amelia; Lubis, Ayu Zulhafni; Tarigan, Beti Susanti; Putri, Dian Primadia; Ariescha, Putri Ayu; Fentiana, nina
Deli Medical and Health Science Journal Vol 2 No 1 (2024): Deli Medical And Health Science Journal (JDMHC)
Publisher : Fakultas Kedokteran, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jdmhc.v2i1.2096

Abstract

Pulmonary TB is ranked as the 10th largest disease in all Pematang Siantar city health centers with a total of 546,324 cases (57.8%).The Kartini Health Center in Pematang Siantar City in 2019 there were 13 people with pulmonary TB, in 2020 there were 15 people, while in 2021 there were 28 people and an increase in 2022 for the October period as many as 49 people.The purpose of this study was to analyze the determinants of potential prevention of pulmonary TB transmission in families.The type of research used is analytic quantitative with a cross sectional design, the number of samples is 44 people.Data collection using a questionnaire.Data analysis used univariate analysis and bivariate analysis with the Chi-Square test.The results showed that the knowledge of pulmonary TB sufferers was in the good category by 50.0%, the attitude was in the good category by 54.5%, the ventilation category was eligible by 52.3%, the coaching of health workers was in the good category by 52.3%, the family support was in the good category by68.2%, prevention of the potential transmission of pulmonary TB in the family is 59.1%.The head of the Puskesmas should carry out socialization or counseling regarding efforts to prevent and control pulmonary TB disease, especially for those around TB patients by involving health cadres, RT, RW, religious leaders, and youth organizations.
Relationship Between Cigarette Smoke Exposure and Laryngeal Histopathology in Rattus novergicus Rats Nasution, Erizal Salam Putra; Herwanto, H. R. Yusa; Zahara, Devira; Aliandri, Aliandri; Lubis, Yuliani M.; Ashar, Taufik; Chrestella, Jessy
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10804

Abstract

Smoking can cause health problems for both active and passive smokers because the toxic substances contained in it cause health problems, especially in the larynx, one of which is laryngeal cancer. Animal studies have shown histopathological changes in mice exposed to cigarette smoke, including increased immune cells and focal inflammation in these mice. The study aims to determine the relationship between cigarette smoke and the number of inflammatory cells, edema, hyperplasia, and dysplasia after exposure to cigarette smoke for 120 minutes in histopathological sampling at observations of 0, 10, 20, 30 and 40 days. This study used a true experimental design model with a post-test only group laboratory experimental design. The results of the study found a significant difference in the number of lymphocytes before and after exposure to cigarette smoke with p = 0.043. There was no significant change in the number of macrophages with p = 0.406 and eosinophils with p = 0.119. There were no histopathological changes, namely edema (p = 0.06), dysplasia (p = 0.126) and hyperplasia (p = 0.960). In conclusion, there is a relationship between cigarette smoke exposure and laryngeal histopathology in Rattus novergicus Rats.