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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Pengabdian Farmasi dan Sains
Ismail, Ihwan
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Standardization of Ethanol Extract of Dioscorea alata L. Variety of Paoateno from Banggai Islands District, Central Sulawesi: Standarisasi Ekstrak Etanol Dioscorea alata L. Varietas Paoateno Asal Kabupaten Banggai Kepulauan Sulawesi Tengah Ismail, Ihwan; Khumaidi, Akhmad; Putri, Ayu Dinawati; Primadia, Rizki; Syamsidi, Armini; Khaerati, Khildah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 9 No. 2 (2023): (October 2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2023.v9.i2.16065

Abstract

Background: Standardizing herbal medicines is crucial for assessing their quality and effectiveness. Objectives: This study aims to determine non-specific and specific standardization parameters for medicinal plants. Non-specific parameters include drying shrinkage, water content, total ash content, acid insoluble ash content, total bacteria, total mold, and metal limits (Pb, Hg, and Cd). Specific parameters involve organoleptic examination, identification of chemical content in extracts, dissolved compounds in specific solvents, total flavonoid content, and qualitative testing of anthocyanin content in the extract. Materials and Methods: An experimental laboratory approach was employed to extract Dioscorea alata L using 96% ethanol, which was later concentrated through a rotary evaporator to obtain a viscous extract. Specific and non-specific parameters were determined using standardized techniques. Results: The extract yielded 3.32% of the initial substance. Drying shrinkage was 19.7769±1.2682%, and specific gravity was 0.6192±0.1476 gram/ml for 5% m/v and 0.5101±3.9591 gram/ml for 10% m/v. Ash content was 0.6793%, with acid insoluble ash content at 0.1895%. Heavy metal contamination for Hg was 0.47 ppm, but undetected for Pb & Cd). The total plate number was 27 x 103 colonies/g, and negative Escherichia coli contamination. The mold count was 39 x 101 colonies/g. Additional specific parameters included the organoleptic properties of the viscous extract (purple color, characteristic odor, and sweet taste), water-soluble compound content (15.63%), ethanol-soluble compound content (14.73%), and a flavonoid content of 76.669 mg EQ/100 mg. Conclusions: The ethanol extract of Dioscorea alata complies with the standard requirements established by the Food and Drug Supervisory Agency. It presents as a viscous extract with a distinct odor, purple-black color, and sweet taste. The extract contains alkaloids, flavonoids, saponins, tannins, steroids, and phenolic compounds, with a total flavonoid content of 76.669 mg. Furthermore, it tested positive for anthocyanins.
UPAYA EDUKASI PENCEGAHAN PENYAKIT DISLIPIDEMIA MELALUI INFORMASI BROSUR PADA LANSIA DI KELURAHAN PANAU, KOTA PALU Ismail, Ihwan; Khildah Khaerati; Muhammad Fahrul Hardani; Andi Athira Masyta; Ririn Hardani; Yuliet
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 3 No. 1 (2024): Oktober 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v3.i1.17469

Abstract

Dyslipidemia is a medical condition caused by a lipid metabolism disorder in the body. In the early stages, dyslipidemia often shows no symptoms or complaints, so many sufferers are unaware of their condition. However, examinations of total cholesterol, low-density lipoprotein (LDL), and triglyceride levels often show elevated results in people with dyslipidemia. Public awareness of the dangers of dyslipidemia remains low, particularly among the elderly. To increase understanding and awareness of dyslipidemia, a community service activity was conducted in Pana Village. This activity began with cholesterol level checks. Following this, a presentation was given on the dangers of dyslipidemia, especially among the elderly, and the importance of maintaining a healthy lifestyle to prevent risks of heart disease, stroke, and even death. This counseling session focused on lifestyle changes that can help control cholesterol levels, such as regulating diet, exercising regularly, and avoiding unhealthy habits like smoking. Out of 95 participants who underwent cholesterol testing, the results showed that 46 elderly individuals (43%) had cholesterol levels below 200 mg/dl, which is still considered within normal limits. However, 54 elderly individuals (57.3%) had cholesterol levels above 200 mg/dl, indicating a high prevalence of dyslipidemia in this age group. These findings emphasize the importance of health education for the elderly, so they become more aware of the risks of dyslipidemia and are motivated to adopt a healthier lifestyle to prevent serious complications.
EDUKASI TERAPI KOMPLEMENTER DIABETES DAN HIPERTENSI PADA MASYARAKAT DESA TOSALE KABUPATEN DONGGALA Ismail, Ihwan; Yuliet; Fahrul Hardani, Muhammad; Khaerati, Khildah
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 1 No. 1 (2022): Oktober 2022
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2022.v1.i1.16110

Abstract

Diabetes melitus dan hipertensi merupakan dua penyakit degeneratif yang mayoritas masyarakat derita diera modern ini. Diabetes melitus merupakan penyakit yang ditandai peningkatan kadar glukosa darah disebabkan retensi insulin, selain bekerja merubah glukosa menjadi glikogen, retensi insulin juga dapat mengakibatkan peningkatan retensi natrium di ginjal dan mengakibatkan aktivitas sistem syaraf simpatik. Retensi natrium dan meningkatnya aktivitas sistem syaraf simpatik merupakan dua hal yang berpengaruh terhadap meningkatnya tekanan darah atau sebut hipertensi. Pengabdian ini bertujuan untuk meningkatkan pengetahuan dan pemahaman masyarakat tentang Diabetes melitus dan hipertensi dan cara penanganannya dengen terapi komplementer berbasis bahan obat tradsional yang ada disekitar masyarakat sehingga dapat meningkatkan kualitas hidup. Metode pelaksanaan pengabdian pada masyarakat ini menggunakan pendekatan pemeriksaan kesehatan meliputi penimbagan berat badan, tekanan darah dengan tensimeter elektrik, kadar gula darah dengan glokotest dan dilanjutkan dengan penyuluhan dengan memberikan edukasi berupa liaflet dan brosur serta booklet terkait terapi komplemeter berbasis bahan alam pada Diabetes melitus dan hipertensi kepada masyarakat Desa Tosale Kecamatan Banawa Selatan Kabupaten Donggala. Hasil pemeriksaan dari 50 warga Desa Tosale diperoleh 2 % (1 warga) memiliki kadar gula darah diatas 200 mg/dl yang dikategorikan dalam diabetes dan 98% (49 warga) memiliki kadar gula darah normal sedangkan pemeriksaan tenanan darah diperoleh 46% warga dengan tekanan dara normal, 28% kategori prehipertensi, 16% hipertensi stage 1 dan 10 % warga mengalami hipertensi stage 2. Kesimpulan pengabdian ini adala terdapat Meningkatnya pengetahuan dan pemahaman masyarakat tentang diabetes melitus dan hipertensi dan cara penanganannya dengen terapi komplementer bahan obat tradsional yang ada disekitar masyarakat sehingga dapat meningkatkan kualitas hidup dan Peningkatan perilaku sehat dengan penggunaan obat berbasis bahan alam
Edukasi Pengenalan Apoteker Cilik dan DAGUSIBU Pada Siswa SDN 4 di Desa Bahomoleo Kecamatan Bungku Tengah Kabupaten Morowali Ismail, Ihwan; Khaerati, Khildah; Yuliet, Yuliet; Yuyun, Yonelian
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 2 (2024): April 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v2.i2.17099

Abstract

Pharmacists are pharmaceutical graduates who have completed pharmacy education and have taken the pharmacist oath, carrying out pharmaceutical work including the manufacturing, quality control of pharmaceutical preparations, security, procurement, storage, distribution, or dispensing of drugs, drug management, prescription drug services, drug information services, as well as drug development, drug substances, and traditional medicines. Currently, the empowerment of health education programs and health services at an early age, especially at the elementary school level, has begun to develop. Children need to receive a lot of information about various professions to increase their insights and stimulate their learning spirit. Based on this, education activities of Junior Pharmacists (Apoteker Cilik) and DAGUSIBU (acronym for Obtaining, Using, Storing, and Disposing of drugs properly) were conducted for elementary school students to introduce the pharmacist profession and educate them on obtaining, using, storing, and disposing of drugs properly. The education was conducted for 5th and 6th-grade students at SDN 4 Bungku Tengah, Morowali, Central Sulawesi, involving 60 students. The method of this activity was through PowerPoint presentations, selection of speakers and materials for Junior Pharmacists and DAGUSIBU, and evaluation of education through question and answer sessions on the material. The evaluation results showed a positive outcome, namely an increase in knowledge about the pharmacist profession and proper drug DAGUSIBU.
Co-Authors Akhmad Khumaidi Andi Athira Masyta Armini Syamsidi Fahrul Hardani, Muhammad Khildah Khaerati Muhammad Fahrul Hardani Primadia, Rizki Putri, Ayu Dinawati Ririn Hardani Yonelian Yuyun Yuliet Yuliet