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All Journal Indonesian Journal of Chemistry Chemistry Indonesian Journal of Chemical Research Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat
Musa, Bulkis
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Engineering Environmental Science Law, Crime, Criminology & Criminal Justice Nursing

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Pemberdayaan Masyarakat Kabupaten Pinrang Melalui Pemanfaatan Kelapa, Kacang Tanah dan Kakao (Kalangka) dalam Proses Fermentasi Menjadi Produk Bahan Makanan Permatasari, Nur Umriani; Natsir, Hasnah; Haedar, Nur; Musa, Bulkis; Situmorang, Sarah Victoria Octovianni; Anggriani, Dhea Faraditha
Abdimas Galuh Vol 6, No 2 (2024): September 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i2.15462

Abstract

Kabupaten Pinrang adalah salah satu kabupaten di Sulawesi Selatan yang terkenal akan kelimpahan kekayaan hayati seperti kacang tanah, kakao, dan kelapa. Ketiga komoditas ini bila diolah melalui tahap fermentasi maka dapat menjadi bioproduk pangan yang berpotensi tinggi dan berkualitas. Fermentasi adalah proses tranformasi kimia substrat organik dengan memanfaatkan aktivitas enzim dari mikroorganisme. Kacang kedelai dan kacang tanah yang difermentasi serta penambahan ragi Rhizopus sp. menghasilkan bioproduk pangan yang dikenal sebagai tempe kalangka yang bermanfaat mencegah penyakit kanker payudara dan jantung koroner. Larutan palape dari limbah air kelapa dan kakao menjadi media asam yang mempercepat pertumbuhan ragi tempe. Nata de coko tinggi kandungan serat dapat meningkatkan kesehatan pencernaan. Metode pembuatan produk tersebut mudah untuk diterapkan. Kegiatan ini bertujuan memberikan pengetahuan akan cara pembuatan tempe, larutan palape dan nata de coko skala home industry, serta menumbuhkan kesadaran berwirausaha yang dapat memperbaiki taraf ekonomi keluarga di Kelurahan Tiroang, Kabupaten Pinrang. Langkah awal yang dilakukan yaitu mensurvei lokasi dan pembuatan ketiga produk dalam skala laboratorium. Pelaksanaan kegiatan dimulai dengan sesi penyuluhan materi manfaat ketiga produk beserta cara pembuatan desain pengemasan yang baik, dan diakhiri dengan sesi diskusi. Kegiatan ini dihadiri oleh target PKM, yaitu kaum ibu rumah tangga serta perwakilan daerah setempat. Kegiatan berlangsung dengan lancar dimana para hadirin mengikuti dengan seksama dan penuh antusias baik dalam sesi diskusi dan praktik. Survei data kegiatan melalui uji pre-test dan post test yang menunjukkan peningkatan pemahaman peserta terkait pelatihan yang diberikan. Diharapkan, kegiatan ini meningkatkan pemanfaatan komoditi lokal secara optimal.
Hydrothermal Synthesis and Characterization of Sodalite from Feldspar Mesawa Minerals Amin, Ida Ifdaliah; Wahab, Abdul Wahid; Taba, Paulina; Mukti, Rino R.; S, Giovanno Alvin; Musa, Bulkis; Azis, Hijrah A.
Indonesian Journal of Chemical Research Vol 12 No 3 (2025): Edition for January 2025
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2025.12-ami

Abstract

The mineral feldspar is a potential raw material in zeolite synthesis because of the high content of SiO2 and Al2O3. Characterization of X-ray diffraction (XRD) and X-ray fluorescence (XRF) on Mesawa feldspar minerals showed high crystallinity and aluminosilicate composition. The synthesis process uses the hydrothermal method with various times and concentrations of NaOH. The sample was mixed with NaOH, stirred until homogeneous at 300 rpm for 1 hour, and transferred to an autoclave. The autoclave was tightly closed and heated in an oven at 170 °C for 72 hours. XRD and XRF analysis revealed that the feldspar mineral had changed to sodalite with a purity of 90.89% and 90.06%; with a yield of 80.89% and 87.36%. FTIR characteristics show a specific peak for sodalite at 422-460 cm-1 related to Si-O bond vibrations, and absorption bands at 698 and 719 cm-1 related to Al-OH vibrations. The SEM results confirmed the morphology of the sodalite resembling balls like raspberries". This research proves that the Mesawa feldspar mineral sample contains type 6 secondary building units, the same blocks as zeolite analcime and cancrinite, so it has the potential as an adsorbent for heavy metals and as a catalyst alternative
Toxicity and α-Amylase Inhibitory Potential of Tagetes erecta Leaf Extract: In Vitro and In Silico Approaches Rasyid, Herlina; Soekamto, Nunuk Hariani; Musa, Bulkis; Siswanto, Siswanto; Labanni, Arniati; Suma, Artania Adnin Tri; Syahrir, Nur Hilal A; Bahrun, Bahrun; Badrawati, Kadek Susi; Yusuf, Mohammad Taufik
Indonesian Journal of Chemistry Vol 25, No 5 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.104489

Abstract

Tagetes erecta is one of traditional herbs with a variety of pharmacological actions. This study attempted to assess the toxicity and antidiabetic activity of T. erecta leaf extract. The extraction was carried out by maceration, then continued with phytochemical analysis. Toxicity of the extract was conducted using the brine shrimp lethality test. The antidiabetic activity was evaluated by α-amylase inhibitory using the 3,5-dinitrosalicylic acid method. The phytochemical of the most active extract was identified using GC-MS and subjected to bind the α-amylase (PDB ID: 2QV4) employing molecular docking. The LC50 values of n-hexane, EtOAc, and MeOH extracts were 33.41, 14.00, and 35.03 ppm, respectively, indicating high toxicity. The antidiabetic activity showed that EtOAc extract has the lowest IC50 value (1053.95 mg/L). Molecular docking analysis revealed the compounds 1–5 has range of binding energy at −4.07 to −4.83 kcal/mol. Acarbose as a positive control showed the lower binding energy at −5.03 kcal/mol, indicated more effective α-amylase inhibitory. This study revealed that T. erecta leaf extract has significant cytotoxic potential, which may warrant further exploration for anticancer applications. However, the relatively weak α-amylase inhibitory and lower binding affinity compared to acarbose imply limited utility as an antidiabetic agent.
Co-Authors Abdul Wahid Wahab Amin, Ida Ifdaliah Anggriani, Dhea Faraditha Artania Adnin Tri Suma Azis, Hijrah A. Badrawati, Kadek Susi Bahrun Bahrun Hasnah Natsir Labanni, Arniati Nunuk Hariani Soekamto Nur Haedar Paulina Taba Permatasari, Nur Umriani Rasyid, Herlina Rino R. Mukti S Siswanto S, Giovanno Alvin Situmorang, Sarah Victoria Octovianni Syahrir, Nur Hilal A. Yusuf, Mohammad Taufik