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Uji Efektivitas Pemberian Salep Ekstrak Etanol Daun Rimbang (Solanum torvum Swartz) Terhadap Penyembuhan Luka Sayat Pada Mencit Putih Jantan (Mus musculus) Diana Novita; Helmice Afriyeni; Rosiana Rizal
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 1 (2023): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v1i1.79

Abstract

Wounds are the loss or damage of part of the body's tissues that come from internal or external, resulting in several effects, namely bleeding, blood clotting, cell death, bacterial contamination and loss of some organ functions. This study aimed to examine the effect of giving ethanol extract ointment from mini-eggplant leaves (Solanum torvum Swartz) on wound healing in male white mice (Mus musculus). As many as 25 animals were induced with cuts and divided into 5 treatment groups, namely the positive control group (vaseline album), the comparison group (povidone iodine ointment 10%) and the treatment group with the ethanol extract of mini-eggplant leaf ointment (Solanum torvum Swartz) with a concentration of 2,5%, 5% and 10%. The ointment was applied according to the treatment group once a day for 14 days, measuring the length and width of the wound daily using a caliper to obtain the area of ​​the wound. The data obtained were then analyzed statistically using two-way ANOVA and continued with Duncan's test. The results of statistical analysis showed that the ethanol extract of mini-eggplant leaf (Solanum torvum Swartz) ointment had a significant effect on the healing of the wound area in male white mice (p<0.05). Mini-eggplant leaf ethanol extract ointment group had effectiveness on wound healing, which was indicated by the smaller the wound area in the test animals. The smallest area is shown at 5% ointment concentration, and the longer the time of administration of the ointment the smaller the incision area is shown on day 14.
Uji Efektivitas Sediaan Sintetis Dan Herbal Terhadap Percepatan Penyembuhan Luka Bakar Derajat II Pada Tikus Putih Jantan Vania Zahara; Helmice Afriyeni; Rosiana Rizal
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 1 (2023): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v1i1.80

Abstract

Burns are injuries that are caused by direct contact with heat, chemicals, electricity and radiation that cause tissue, muscle, nerve skin damage and tearing of blood vessels to disrupt the body's balance. The purpose of this study was to determine the effect of preparation and time on the reduction of burn area in male white rats. All rats were induced by burns and divided into 5 groups, namely the bioplacenton preparation group, synergy herbal oil, aloevera medigel, then treated with the preparation for 28 days. Wound area measurements were carried out on days 0, 4, 8, 12, 16, 20, 24 and 28, then histopathological examination of the rat skin tissue was carried out on the final day. The data from the study measuring the area of ​​the wound were analyzed using the Two-Way Anova method followed by Duncan's, then quantitative descriptive histopathology using the Kruskal Wallis method. The results of statistical analysis of preparation and time had a significant effect on decreasing burn area in male white rats (<0.05). The dosage and time groups have effectiveness in reducing wound area, where the percentage of the largest decrease in wound area is in the herbal preparation of Medigel aloevera and the longer the time of administration of the preparation the greater the percentage decrease in wound area. In addition, the histopathological state of rat skin tissue at the end of the day for all groups was in a mature state in epithelial cells and 6-10 blood vessel cells with score 2.
Hubungan Tingkat Pengetahuan Dan Sikap Mahasiswa Terhadap Kejadian Acne Vulgaris Muhamad Aldo Putra; Helmice Afriyeni; Dwisari Dillasamola
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 1 (2023): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v1i1.81

Abstract

So far, there are still many people who prioritize and assume that physical appearance is the key in interacting both directly and interacting on social media. In the campus environment, students have very wide interactions and are concerned with appearance to bind self-confidence, therefore the importance of students' knowledge and attitudes towards the incidence of acne vulgaris. This study aims to determine whether or not there is a relationship between the level of knowledge and attitudes of students towards acne vulgaris. This study used descriptive analytic method with cross sectional design and the sampling used random sampling method and data analysis using chi-square. The results obtained were in the knowledge test of Dharma Andalas University Padang students the majority were in the good category (82.78%) and the results on the attitude test were the majority in the sufficient category (65.57%). In the results of the chi-square test analyzing the relationship between knowledge and attitudes towards the incidence of acne vulgaris, the p value = 0.039 (p < 0.05) and p = 0.813 (p> 0.05) and in the analysis of knowledge and attitude, p = 0.796 ( p>0.05). The conclusion in this study is that there is a relationship between knowledge and the incidence of acne vulgaris, there is no relationship between attitudes towards the incidence of acne vulgaris and there is no significant correlation between knowledge and attitudes of students.
Pengaruh Pemberian Informasi Obat Terhadap Tingkat Pengetahuan Penggunaan Antibiotik Pada Pasien Di Puskesmas Belimbing Kota Padang Nadira Atiqah Ricardo; Helmice Afriyeni; Rahmi Yosmar; Rosiana Rizal
Jurnal Sains Farmasi Dan Kesehatan Vol. 2 No. 1 (2024): Mei - Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v2i1.1454

Abstract

Antibiotics are drugs that function to prevent and treat infections caused by bacteria. Antibiotics given to patients irrationally can cause resistance. Antibiotic resistance is a condition where the body becomes resistant to antibiotics. Inappropriate use of antibiotics is influenced by several factors, such as knowledge problems. One of the efforts in improving knowledge about the use of antibiotics is by providing information. Providing drug information is part of pharmaceutical services that include the selection, use, determination of drugs, and how to administer the right drugs. The purpose of this study was to determine the knowledge of patients in the use of antibiotics before and after providing information and whether there is a significant influence between the provision of information on the level of knowledge. This study is descriptive with accidental sampling method using pretest and posttes design. The instrument used was a questionnaire, then the results were analyzed using chi square test analysis. In this study, the level of knowledge of respondents after being given information about the use of antibiotics at the highest percentage was in the less category (73.2%) and after being given information was in the good category (99.9%). There was no significant influence between the level of knowledge of respondents before and after giving information about antibiotics with a p value of 0.161.