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All Journal Eduvest - Journal of Universal Studies Indonesian Journal of Biomedicine and Clinical Sciences
Setyono, Alfred
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Social Sciences

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Serpentine supravenous hyperpigmentation (SSH) in nasopharyngeal carcinoma patient on docetaxel and carboplatin chemotherapy: a case report Sutiawan, Indry Salonika; Puspawati, Ni Made Dwi; Martalova AJ, Adelia; Setyono, Alfred; Devi, Putu Akopita; Setyawati, Ni Kadek
Indonesian Journal of Biomedicine and Clinical Sciences Vol 56 No 2 (2024)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v56i2.13006

Abstract

Serpentine supravenous hyperpigmentation (SSH) is a rare but unique side effect of intravenous anticancer. It manifests as linear hyperpigmentation eruption on the skin that radiates along the superficial vein accompanied by mild pain and/or itch. This SSH does not cause systemic alterations, however, most patients complained about its cosmetic effects. The diagnosis of SSH can be made clinically, although histopathological examinations can aid in excluding differential diagnoses. We reported a case of SSH found in a nasopharyngeal cancer patient during docetaxel and carboplatin chemotherapy. It is a potentially alarming interface dermatitis that is not lot reported in the literature. It was reported, the patient tolerated the second and third cycles well with less severe side effects when premedicated with 250 mL NaCl 0.9% bolus intravenously before and after chemotherapy sessions, 10 mg cetirizine every 24 hr orally, and desoximetasone cream 0.25% every 12 hr topically added.
Molluscum Contagiosum Profile At The Dermatology And Venereology Polyclinic Of Prof. I.G.N.G. Ngoerah Central General Hospital Denpasar Salonika Sutiawan, Indry; Praharsini, I Gusti Ayu Agung; Martalova AJ, Adelia; Setyono, Alfred; Devi, Putu Akopita; Setyawati, Ni Kadek
Eduvest - Journal of Universal Studies Vol. 4 No. 4 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i4.1175

Abstract

Molluscum contagiosum (MC) is a viral infectious disease caused by the Molluscum Contagiosum Virus (MCV). There are four subtypes of MCV (MCV-1, MCV-2, MCV-3, and MCV-4). The worldwide incidence of MK infection is estimated to be around 2% to 8%, while in the HIV/AIDS population, it is approximately 5% to 18%. To date, there is limited research reporting on the profile of MC patients in Indonesia. This is a descriptive cross-sectional research design. Data were obtained retrospectively and collected from the medical records of patients with molluscum contagiosum who visited the Dermatology and Venereology Polyclinic at Prof. I.G.N.G. Ngoerah General Hospital in Denpasar, Bali, from January 2018 to December 2020. In this study of molluscum contagiosum infection at the Dermatology and Venereology Polyclinic of Sanglah General Hospital in Denpasar, Bali, during the period of January 2018 to December 2020, the majority of participants were aged between 18-44 years (61.1%) and were male (61.1%). Most participants were from Bali (77.8%) and were married (55.6%). Moreover, the majority of participants were sexually active (77.8%) and had a negative HIV status (55.6%). Concerning sexual orientation, most participants identified as heterosexual (83.3%). Regarding the type of therapy received, most participants underwent enucleation (55.5%) and combination therapy (22.2%). Broad public education, especially for parents, regarding molluscum contagiosum should be enhanced to support more effective healthcare efforts encompassing treatment, prevention, and health promotion.
Profile of Psoriatic Arthritis Patients in the Dermatology and Venereology Clinic at RSUP Prof. I.G.N.G. Ngoerah Denpasar for the Period of 2021-2023 Setyono, Alfred; Sudarsa, Prima Sanjiwani Saraswati; Martalova, Adelia; Sutiawan, Indry Salonika; Setyawati, Ni Kadek; Devi, Putu Akopita
Eduvest - Journal of Universal Studies Vol. 4 No. 12 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i12.1528

Abstract

Psoriatic arthritis (PsA) presents a significant challenge due to its high prevalence and morbidity rates. Psoriasis vulgaris affects an estimated 0.19-2% of the global population, with approximately 30% of these individuals progressing to experience psoriatic arthritis. Methods: This is a retrospective study using medical records of psoriatic arthritis patients at the Dermatology and Venereology Clinic. Result and Discussion: A total of 168 psoriasis patients were assessed at the Dermatology and Venereology Clinic of Prof. I.G.N.G Ngoerah Hospital from 2021 to 2023. Among them, 58 cases were also diagnosed with Psoriatic Arthritis (PsA), accounting for 35.1% of the sample. Of these, 33 patients were male (67.3%) and 16 were female (32.7%). The highest prevalence was observed in the 40-59 age group (51%). Additionally, 77.5% of patients had a Body Surface Area (BSA) greater than 10%, 61.2% had a Psoriasis Area Severity Index (PASI) score of severe psoriasis (>10), and 49.0% had a Dermatology Life Quality Index (DLQI) score indicating moderate impact (6-10). Similarly, 49.0% of patients had a moderate Disease Activity Index for Psoriatic Arthritis (DAPSA) score (>4-14). The study revealed a PsA prevalence of 35.1%, which surpasses global averages, likely due to the hospital's role as a tertiary referral center for severe psoriasis cases. Conclusion: The prevalence of Psoriatic Arthritis (PsA) among patients treated is still high, particularly among male patients aged 40-59 years who have severe psoriasis based on BSA (Body Surface Area), PASI (Psoriasis Area Severity Index), and DLQI (Dermatology Life Quality Index) criteria.
Co-Authors Devi, Putu Akopita I Gusti Ayu Agung Praharsini Martalova AJ, Adelia Martalova, Adelia Ni Kadek Setyawati, Ni Kadek Ni Made Dwi Puspawati Prima Saraswati Sanjiwani Sudarsa Salonika Sutiawan, Indry Sutiawan, Indry Salonika