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All Journal Bali Dermatology and Venereology Journal Eduvest - Journal of Universal Studies Indonesian Journal of Biomedicine and Clinical Sciences Journal Management and Hospitality
Ni Kadek Setyawati, Ni Kadek
Institut Hindu Dharma Negeri Denpasar
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Social Sciences

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Glucocorticoid-induced hyperglycemia (GIH) in pemphigus vulgaris patient at Bangli District General Hospital: A case report Setyawati, Ni Kadek; Sari, A. A. I. A. Nindya; Mahariski, Pande Agung
Bali Dermatology and Venereology Journal Vol 2, No 2 (2019)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v2i2.19

Abstract

Background: Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous blistering and erosion. This is rare, but greatly affects the patient’s life quality and often cause complication of disease and therapy. Hyperglycemia is a complication due to steroid use called glucocorticoid-induced hyperglycemia (GIH). This case report describes hyperglycemia in PV treatment, which later can be a consideration of PV management.Case: A 44-year-old male patient complained of painful lesions on almost the whole body with a form of bullae, erosion, crusting, brittle, the Nikolsky sign (+), and Asboe-Hansen sign (+). The patient was diagnosed with PV. After he had supportive therapy and high-doses of methylprednisolone, his blood sugar is increased. Patients diagnosed by hyperglycemia state due to steroid use, then given insulin as therapy. The patient diagnosed with PV based on history taking and physical examination, but the histopathologic examination wasn’t done due to lack of modality at the hospital. The steroid was given as an immunosuppressive. Be the main therapy for PV, steroids lead hyperglycemia due to disruption of glucose metabolism, thereby increasing insulin resistance in tissues. The diagnosis of hyperglycemia due to steroid use is made in a patient with a normal sugar level before PV therapy. It occurred within the first 1-2 days of therapy. In these patients, diagnosis confirmed by increasing pre-prandial, 2 h post-prandial, and any-time glucose level, after two days methylprednisolone administration. Collaboration with internal medicine colleagues is needed.Conclusion: PV treatment with steroids can induce hyperglycemia, which is dangerous. The understanding mechanism is needed to make early detection and provide therapy properly.
Serpentine supravenous hyperpigmentation (SSH) in nasopharyngeal carcinoma patient on docetaxel and carboplatin chemotherapy: a case report Sutiawan, Indry Salonika; Puspawati, Ni Made Dwi; Martalova AJ, Adelia; Setyono, Alfred; Devi, Putu Akopita; Setyawati, Ni Kadek
Indonesian Journal of Biomedicine and Clinical Sciences Vol 56 No 2 (2024)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v56i2.13006

Abstract

Serpentine supravenous hyperpigmentation (SSH) is a rare but unique side effect of intravenous anticancer. It manifests as linear hyperpigmentation eruption on the skin that radiates along the superficial vein accompanied by mild pain and/or itch. This SSH does not cause systemic alterations, however, most patients complained about its cosmetic effects. The diagnosis of SSH can be made clinically, although histopathological examinations can aid in excluding differential diagnoses. We reported a case of SSH found in a nasopharyngeal cancer patient during docetaxel and carboplatin chemotherapy. It is a potentially alarming interface dermatitis that is not lot reported in the literature. It was reported, the patient tolerated the second and third cycles well with less severe side effects when premedicated with 250 mL NaCl 0.9% bolus intravenously before and after chemotherapy sessions, 10 mg cetirizine every 24 hr orally, and desoximetasone cream 0.25% every 12 hr topically added.
Molluscum Contagiosum Profile At The Dermatology And Venereology Polyclinic Of Prof. I.G.N.G. Ngoerah Central General Hospital Denpasar Salonika Sutiawan, Indry; Praharsini, I Gusti Ayu Agung; Martalova AJ, Adelia; Setyono, Alfred; Devi, Putu Akopita; Setyawati, Ni Kadek
Eduvest - Journal of Universal Studies Vol. 4 No. 4 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i4.1175

Abstract

Molluscum contagiosum (MC) is a viral infectious disease caused by the Molluscum Contagiosum Virus (MCV). There are four subtypes of MCV (MCV-1, MCV-2, MCV-3, and MCV-4). The worldwide incidence of MK infection is estimated to be around 2% to 8%, while in the HIV/AIDS population, it is approximately 5% to 18%. To date, there is limited research reporting on the profile of MC patients in Indonesia. This is a descriptive cross-sectional research design. Data were obtained retrospectively and collected from the medical records of patients with molluscum contagiosum who visited the Dermatology and Venereology Polyclinic at Prof. I.G.N.G. Ngoerah General Hospital in Denpasar, Bali, from January 2018 to December 2020. In this study of molluscum contagiosum infection at the Dermatology and Venereology Polyclinic of Sanglah General Hospital in Denpasar, Bali, during the period of January 2018 to December 2020, the majority of participants were aged between 18-44 years (61.1%) and were male (61.1%). Most participants were from Bali (77.8%) and were married (55.6%). Moreover, the majority of participants were sexually active (77.8%) and had a negative HIV status (55.6%). Concerning sexual orientation, most participants identified as heterosexual (83.3%). Regarding the type of therapy received, most participants underwent enucleation (55.5%) and combination therapy (22.2%). Broad public education, especially for parents, regarding molluscum contagiosum should be enhanced to support more effective healthcare efforts encompassing treatment, prevention, and health promotion.
Anemia on Chronic Disease in Leprosy Before and After Completing Multi Drug Therapy Setyawati, Ni Kadek; Rusyati, Luh Made Mas; Indira, I Gusti Ayu Agung Elis; Praharsini, I Gusti Ayu Agung; Darmaputra, I Gusti Nyoman; Karmila, I Gusti Ayu Agung Dwi
Eduvest - Journal of Universal Studies Vol. 4 No. 9 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i9.1500

Abstract

Leprosy infection can cause anemia due to chronic disease (ACD). Multidrug therapy (MDT) for leprosy patients can overcome the infection. This study aims to determine the comparison in the incidence of ACD before and three months after MDT to leprosy patients at Prof. Dr. I G.N.G. Ngoerah Central General Hospital. A cross-sectional analytical observational study was conducted using secondary data from medical records of leprosy patients. A total of 142 samples were taken through total sampling. Data taken included gender, domicile, type of leprosy suffered, incidence of ACD, hemoglobin levels, and erythrocyte index before and three months after completing MDT leprosy therapy. Data analysis was carried out with SPSS version 21 using chi-square and paired t tests (dependent t-test), p value <0.05 means significant. The incidence of ACD was significantly higher before leprosy MDT therapy compared to 3 months after completing leprosy MDT therapy (49.3% vs. 16.2%; p value <0.001) with a prevalence ratio of 3.043 (2.021-4.584) CI95%. The mean hemoglobin levels, MCV, MCH, and MCHC levels 3 months after MDT leprosy therapy were significantly higher than before receiving MDT therapy (13.73 ± 1.47 vs. 12.40 ± 2.06 g/dL; p value <0.001), (88.18±7.22 vs. 84.07±9.55 fl; p value<0.001), (28.32±2.76 vs. 26.72±3.17 pg/cell; p value <0.001), (32.03±1.30 vs. 31.69±1.47%; p value<0.001). The incidence of ACD was significantly higher before MDT compared to 3 months after MDT. Mean hemoglobin, MCV, MCH, and MCHC levels were found to be significantly higher 3 months after MDT compared to before receiving MDT.
Profile of Psoriatic Arthritis Patients in the Dermatology and Venereology Clinic at RSUP Prof. I.G.N.G. Ngoerah Denpasar for the Period of 2021-2023 Setyono, Alfred; Sudarsa, Prima Sanjiwani Saraswati; Martalova, Adelia; Sutiawan, Indry Salonika; Setyawati, Ni Kadek; Devi, Putu Akopita
Eduvest - Journal of Universal Studies Vol. 4 No. 12 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i12.1528

Abstract

Psoriatic arthritis (PsA) presents a significant challenge due to its high prevalence and morbidity rates. Psoriasis vulgaris affects an estimated 0.19-2% of the global population, with approximately 30% of these individuals progressing to experience psoriatic arthritis. Methods: This is a retrospective study using medical records of psoriatic arthritis patients at the Dermatology and Venereology Clinic. Result and Discussion: A total of 168 psoriasis patients were assessed at the Dermatology and Venereology Clinic of Prof. I.G.N.G Ngoerah Hospital from 2021 to 2023. Among them, 58 cases were also diagnosed with Psoriatic Arthritis (PsA), accounting for 35.1% of the sample. Of these, 33 patients were male (67.3%) and 16 were female (32.7%). The highest prevalence was observed in the 40-59 age group (51%). Additionally, 77.5% of patients had a Body Surface Area (BSA) greater than 10%, 61.2% had a Psoriasis Area Severity Index (PASI) score of severe psoriasis (>10), and 49.0% had a Dermatology Life Quality Index (DLQI) score indicating moderate impact (6-10). Similarly, 49.0% of patients had a moderate Disease Activity Index for Psoriatic Arthritis (DAPSA) score (>4-14). The study revealed a PsA prevalence of 35.1%, which surpasses global averages, likely due to the hospital's role as a tertiary referral center for severe psoriasis cases. Conclusion: The prevalence of Psoriatic Arthritis (PsA) among patients treated is still high, particularly among male patients aged 40-59 years who have severe psoriasis based on BSA (Body Surface Area), PASI (Psoriasis Area Severity Index), and DLQI (Dermatology Life Quality Index) criteria.
Blue Economy and the Attraction of Beach Tourism AURELIA, Devina; SETYAWATI, Ni Kadek; MORUK, Mariane Clarissa; CAHYANI, Ni Made Melia
Journal Management and Hospitality Vol. 2 No. 1 (2024): Journal Management and Hospitality (December-March 2024)
Publisher : PT Batara Swastika Harati

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The Blue Economy is a sustainable development strategy that integrates economic growth, marine environmental conservation, and social welfare. This concept emphasizes the importance of balancing the utilization of marine resources with long-term ecosystem sustainability. In the context of tourism, the Blue Economy offers opportunities to develop coastal attractions that are both economically valuable and environmentally responsible. This article aims to analyze the relationship between the Blue Economy and the development of coastal tourism attractions. The method applied is a systematic literature review of 15 relevant national and international journals that discuss sustainable marine resource management, coastal tourism, and community involvement. The findings show that the application of Blue Economy principles not only ensures the sustainability of coastal ecosystems but also increases economic added value through sustainable tourism, marine-based product innovation, and local community empowerment. Furthermore, this study emphasizes the importance of multi-stakeholder collaboration including government, private sector, and local communities in designing policies and strategies that encourage sustainable coastal tourism development rooted in the Blue Economy framework.
Co-Authors AURELIA, Devina CAHYANI, Ni Made Melia Darmaputra, I Gusti Nyoman Devi, Putu Akopita I Gusti Ayu Agung Dwi Karmila I Gusti Ayu Agung Praharsini Indira, I Gusti Ayu Agung Elis Luh Made Mas Rusyati Mahariski, Pande Agung Martalova AJ, Adelia Martalova, Adelia MORUK, Mariane Clarissa Ni Made Dwi Puspawati Prima Saraswati Sanjiwani Sudarsa Salonika Sutiawan, Indry Sari, A. A. I. A. Nindya Setyono, Alfred Sutiawan, Indry Salonika