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All Journal Bali Dermatology and Venereology Journal Indonesian Journal of Biomedicine and Clinical Sciences Journal Management and Hospitality
Ni Kadek Setyawati, Ni Kadek
Institut Hindu Dharma Negeri Denpasar
Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Glucocorticoid-induced hyperglycemia (GIH) in pemphigus vulgaris patient at Bangli District General Hospital: A case report Setyawati, Ni Kadek; Sari, A. A. I. A. Nindya; Mahariski, Pande Agung
Bali Dermatology and Venereology Journal Vol 2, No 2 (2019)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v2i2.19

Abstract

Background: Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous blistering and erosion. This is rare, but greatly affects the patient’s life quality and often cause complication of disease and therapy. Hyperglycemia is a complication due to steroid use called glucocorticoid-induced hyperglycemia (GIH). This case report describes hyperglycemia in PV treatment, which later can be a consideration of PV management.Case: A 44-year-old male patient complained of painful lesions on almost the whole body with a form of bullae, erosion, crusting, brittle, the Nikolsky sign (+), and Asboe-Hansen sign (+). The patient was diagnosed with PV. After he had supportive therapy and high-doses of methylprednisolone, his blood sugar is increased. Patients diagnosed by hyperglycemia state due to steroid use, then given insulin as therapy. The patient diagnosed with PV based on history taking and physical examination, but the histopathologic examination wasn’t done due to lack of modality at the hospital. The steroid was given as an immunosuppressive. Be the main therapy for PV, steroids lead hyperglycemia due to disruption of glucose metabolism, thereby increasing insulin resistance in tissues. The diagnosis of hyperglycemia due to steroid use is made in a patient with a normal sugar level before PV therapy. It occurred within the first 1-2 days of therapy. In these patients, diagnosis confirmed by increasing pre-prandial, 2 h post-prandial, and any-time glucose level, after two days methylprednisolone administration. Collaboration with internal medicine colleagues is needed.Conclusion: PV treatment with steroids can induce hyperglycemia, which is dangerous. The understanding mechanism is needed to make early detection and provide therapy properly.
Serpentine supravenous hyperpigmentation (SSH) in nasopharyngeal carcinoma patient on docetaxel and carboplatin chemotherapy: a case report Sutiawan, Indry Salonika; Puspawati, Ni Made Dwi; Martalova AJ, Adelia; Setyono, Alfred; Devi, Putu Akopita; Setyawati, Ni Kadek
Indonesian Journal of Biomedicine and Clinical Sciences Vol 56 No 2 (2024)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v56i2.13006

Abstract

Serpentine supravenous hyperpigmentation (SSH) is a rare but unique side effect of intravenous anticancer. It manifests as linear hyperpigmentation eruption on the skin that radiates along the superficial vein accompanied by mild pain and/or itch. This SSH does not cause systemic alterations, however, most patients complained about its cosmetic effects. The diagnosis of SSH can be made clinically, although histopathological examinations can aid in excluding differential diagnoses. We reported a case of SSH found in a nasopharyngeal cancer patient during docetaxel and carboplatin chemotherapy. It is a potentially alarming interface dermatitis that is not lot reported in the literature. It was reported, the patient tolerated the second and third cycles well with less severe side effects when premedicated with 250 mL NaCl 0.9% bolus intravenously before and after chemotherapy sessions, 10 mg cetirizine every 24 hr orally, and desoximetasone cream 0.25% every 12 hr topically added.
Blue Economy and the Attraction of Beach Tourism AURELIA, Devina; SETYAWATI, Ni Kadek; MORUK, Mariane Clarissa; CAHYANI, Ni Made Melia
Journal Management and Hospitality Vol. 2 No. 1 (2024): Journal Management and Hospitality (December-March 2024)
Publisher : PT Batara Swastika Harati

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Abstract

The Blue Economy is a sustainable development strategy that integrates economic growth, marine environmental conservation, and social welfare. This concept emphasizes the importance of balancing the utilization of marine resources with long-term ecosystem sustainability. In the context of tourism, the Blue Economy offers opportunities to develop coastal attractions that are both economically valuable and environmentally responsible. This article aims to analyze the relationship between the Blue Economy and the development of coastal tourism attractions. The method applied is a systematic literature review of 15 relevant national and international journals that discuss sustainable marine resource management, coastal tourism, and community involvement. The findings show that the application of Blue Economy principles not only ensures the sustainability of coastal ecosystems but also increases economic added value through sustainable tourism, marine-based product innovation, and local community empowerment. Furthermore, this study emphasizes the importance of multi-stakeholder collaboration including government, private sector, and local communities in designing policies and strategies that encourage sustainable coastal tourism development rooted in the Blue Economy framework.
Co-Authors AURELIA, Devina CAHYANI, Ni Made Melia Devi, Putu Akopita Mahariski, Pande Agung Martalova AJ, Adelia MORUK, Mariane Clarissa Ni Made Dwi Puspawati Sari, A. A. I. A. Nindya Setyono, Alfred Sutiawan, Indry Salonika