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Journal : Widya Warta

DAYA ANTIBAKTERI EKSTRAK ETANOL BUAH PACE (Morinda citrifolia, L) TERHADAP BAKTERI Shigella dysentriae SECARA IN VITRO SERTA PROFIL KROMATOGRAFI LAPIS TIPIS Nurcahyani, Diah
Widya Warta No. 02 Tahun XL/Juli 2016
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Pace fruit (Morinda citrifolia, L) is known by people as an ingredient of beverage. In addition, the people take it as medicine for dysentery. It was carried out a study with the intention of observing the antibacterial activity of extract of pace fruit, on bacteria Shigella dysentriae. The dried fruit was pounded to powder then a filtering was made employing Soxhlet, with ethanol as the extractor. The extract had been obtained was then evaporated to achieve viscosity and it was made a serial of dilution in various concentration, namely, 2,5%, 5%, 10%, and 20% b/v by propilen glikol solvent and an examination was performed for the activity of antibacterial involved. To negative control it was used propilen glikol and while positive control it was used kanamizi. Bacteria used was Shigella dysentriae. The examination adapted the method of Nutrient gel solid diphusy to see Minimal Obstacle Rate (Kadar Hambat Minimal). The outcome of antibacterial test showed that the extract of pace demonstrated antibacterial activity on Shigella dysentriae, at a minimal obstacle rate 20% b/v. To see the chemical content of pace fruit, it was performed thin chromatography on the extract of pace fruit to observe the profile of spots involved. The outcome of examination for the content of compound under ultra violet ray 254 nm and 366 nm, showed that the extract of pace was possibly containing fenol compound.
PENGARUH KAPSUL EKSTRAK TEMULAWAK (Curcuma xanthorrhiza Roxb.) TERHADAP KADAR LDL DAN HDL KOLESTEROL PADA MENCIT HIPERLIPIDEMIA Nurcahyani, Diah
Widya Warta No. 01 Tahun XLIII/Januari 2019
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Hyperlipidemia is an increase in blood lipid levels. Hyperlipidemia is strongly associated with changes in HDL levels and increases in LDL levels. One alternative natural ingredient to  reduce cholesterol levels in the blood is ginger (Curcuma xanthorrhizaRoxb.). The purpose of this study was to determine the effect of capsules of temulawak extract (Curcuma xanthorrhizaRoxb.) on decreasing LDL and HDL cholesterol levels in hyperlipidemic mice. This study used 12 mice (Mus musculus L.). Models of hyperlipidemia animals were made with induction of egg yolk for 7 days. Therapy was carried out for 7 days with a curcuma xanthorrhizaRoxb extract capsule of 3x0.2 ml / day and 3x0.4 ml / day. The analysis used in this study is the One Way Analysis of Variance (ANOVA) with Duncan's advanced test for LDL and HDL levels. The results of the data analysis can be concluded that the curcuma xanthorrhizaRoxb Extract capsule significantly reduced LDL levels and significantly increased HDL levels in hyperlipidemic mice (Mus musculus L.).
ANALISIS MUTU PELAYANAN PETUGAS FARMASI DAN KETERSEDIAAN OBAT TERHADAP KEPUASAN PASIEN RAWAT JALAN DI RS SANTA CLARA MADIUN TAHUN 2019 Nurcahyani, Diah; Kartikaningrum, Vidya
Widya Warta No. 02 Tahun XLIII/Juli 2019
Publisher : Universitas Katolik Widya Mandala Surabaya Kampus Kota Madiun

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Abstract

Service quality, pharmaceutical providers, and the availability of medicines determine the outpatients’ satisfaction in the Department of Hospital Pharmaceutical Installation (IFRS). The phenomena, found in RS Santa Clara Madiun, are that and patients usually wait too long to get medicines, and the presence of empty drugs. The objective of the research was to find out the influence of the service quality pharmaceutical providers and the availability of medicines on the outpatients’ satisfaction in RS Santa Clara, in June 2019h . The research was a cross sectional method on 100 outpatients, using accidental sampling technique. The data were gathered by using questionnaires and analyzed by using bilinear regression test (α= 0,05). The result of the research showed that the variables of pharmaceutical providers and the availability of medicines influenced patients’ satisfaction (p < 0.005). The variable of the availability of medicines had the most dominant influence on outpatients’ satisfaction at the coefficient value of (β) 0.853). It is recommended that the management of RS Santa Clara Madiun furnish the availability of medicines and the facility of the IFRS waiting rooms, and pharmaceutical providers increase the dimension of the guarantee in order to improve the performance of the pharmaceutical providers and the information service about medicines.