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Formulation Of Pipe-Reducing Paste (Blushon) Using Young Jati Leaf Extract (Tectona Grandis L.F) As Natural Dye Novrita, Sisri; Audry Reji Renata Griffin; Revi Yenti; Larysa Fernenda
JFARM - Jurnal Farmasi Vol. 2 No. 2 (2024)
Publisher : Yayasan Rahmatan Fiddunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jfarm.v2i2.910

Abstract

Young teak leaves (Tectona Grandis L.f) contain anthocyanin pigments which can give a red color. Utilization of anthocyanin pigments can be used as natural dyes. The purpose of this study was to formulate a blush paste preparation using young teak leaf extract (Tectona grandis l.f) as a natural dye. This study uses an experimental method. The extraction method for teak leaf dyes uses the maceration method. In this study, 3 formulas for blush on were prepared in the form of pastes with various concentrations of 2.0%, 2.5% and 3% thick extract of teak leaves. Then a physical evaluation of the blush preparation was carried out which included organoleptic, homogeneity, pH, spreadability, irritation, hedonic, and stability tests. Based on the organoleptic tests carried out, it indicates that there is a change in color and stability is not good. The results of the spreadability test did not meet the standards and the results of the homogeneity test and the pH test showed that there were no coarse grains then the pH test was around 6 (according to the general skin pH interval) and did not cause irritation so it was safe to use on the skin. The results of the physical evaluation of the blush paste from young teak leaf extract met the standards. So teak leaf extract (Tectona grandis l.f) can be formulated as a blush paste. The results of the hedonic test showed that the blush paste using young teak leaf extract (Tectona grandis l.f) with a concentration of 2% was the most preferred by the panelists.
Formulasi dan Evaluasi Spray Hand Sanitizer Ekstrak Etanol Daun Kemangi (Ocimum basilicum L.) Terhadap Staphylococcus aureus Novrita, Sisri; Berlian Aftynar Ruwi; Revi Yenti
JFARM - Jurnal Farmasi Vol. 2 No. 2 (2024)
Publisher : Yayasan Rahmatan Fiddunya Wal Akhirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58794/jfarm.v2i2.919

Abstract

Daun kemangi (Ocimum basilicum L.) merupakan tanaman yang memiliki aktivitas sebagai antibakteri. Daun kemangi memiliki banyak kandungan yang utama adalah flavonoid, saponin, dan alkaloid. Tujuan penelitian ini adalah memformulasi ekstrak daun kemangi sebagai spray hand sanitizer dan menguji aktivitas antibakterinya terhadap Staphylococcus aureus menggunakan metode replika. Penelitian ini menggunakan berbagai konsentrasi ekstrak etanol daun kemangi (Ocimum basilicum L.) pada sediaan spray hand sanitizer yaitu 0%; 2%; 4%; 6%. Kemudian dilakukan uji stabilitas fisik dengan parameter uji meliputi uji organoleptis, viskositas, homogenitas, pH, stabilitas, uji iritasi, uji kecepatan pengeringan dan uji aktivitas antibakteri. Berdasarkan hasil formulasi dan evaluasi sediaan spray hand sanitizer yang yang dibuat dalam berbagai konsentrasi yaitu 0%; 2%; 4%; 6% pada Pengujian organoleptis, uji viskositas, uji homogenitas, uji pH dan uji stabilitas untuk ketiga formula stabil selama masa penyimpanan. Kemudian untuk hasil uji aktivitas antibakteri yang dianalisis ANOVA satu arah menunjukkan bahwa pengaruh sediaan spray hand sanitizer ekstrak etanol daun kemangi terhadap pertumbuhan bakteri Staphylococcus aureus memiliki nilai sangat signifikan sebesar 0,001 (p˂0,05) yang dilanjutkan uji Duncan memberikan nilai sangat signifikan antara sediaan Formula F0, F1, F2, dan F3 bahwa semakin tinggi konsentrasi ekstrak etanol daun kemangi (Ocimum basilicum L.) pada sediaan spray hand sanitizer maka semakin besar pula aktivtas antibakteri yang diberikan. Maka dapat disimpulkan bahwa ekstrak etanol daun kemangi (Ocimum basilicum L.) dapat diformulasikan menjadi sediaan spray hand sanitizer atau dikenal dengan antiseptik tangan dan memiiki aktivitas antibakteri yang baik.
PHENOLIC TOTAL CONTENT AND ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT OF MARKISA KONYAL (Passiflora ligularis) SEEDS Sari, Tisa Mandala; Verawati; Revi Yenti; Ayu Anggraini
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2905

Abstract

Konyal passion fruit (Passiflora ligularis f. lobata) has been widely used as fruit juice by the community, it is necessary to conduct research to explore the potential of konyal passion fruit as a natural medicine. This study aims to determine the total phenolic compound content and antioxidant activity of ethanol extract from konyal passion fruit seeds using UV-Vis Spectrophotometry method. The sample was macerated with 70% and 96% ethanol solvent, repeated three times and the filtrate was concentrated using a rotary evaporator at 40°C. The extract obtained was determined by the concentration of phenolic compounds using the Follin - Ciocalteau method and the antioxidant activity test using the DPPH method with gallic acid as a comparison compound. The determination of the total phenolic compound content was obtained at 77,73 µg/mL at a wavelength of 747 nm. The antioxidant activity test of gallic acid obtained IC50: 2,04 µg/mL, and the antioxidant activity test of the sample obtained IC50: 21,89 µg/mL at a wavelength of 515 nm. Based on the IC50 value, it can be concluded that the antioxidant activity of the ethanolic extract of passion fruit seeds is in the very strong category, namely in the range <50 µg/mL. The equivalence of antioxidant activity of ethanolic extract of konyal passion fruit seeds with gallic acid is 1:10,73 mg, meaning that 1 mg gram of gallic acid is equivalent to 10,73 mg of ethanolic extract of konyal passion fruit seeds.
Co-Authors Audry Reji Renata Griffin Ayu Anggraini Berlian Aftynar Ruwi Larysa Fernenda Novrita, Sisri Tisa Mandala Sari Verawati