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MANFAAT ANTIOKSIDAN DAUN SALAM TERHADAP KADAR GLUKOSA DARAH DAN PENURUNAN APOPTOSIS NEURON DI HIPPOCAMPUS OTAK TIKUS YANG MENGALAMI DIABETES Ayu Anggraini
Jurnal Medika Hutama Vol. 2 No. 01 Oktober (2020): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Encephalopathy diabetes is a complication of diabetes mellitus due to changes in morphology and abnormal physiological functions of the brain, due to chronic hyperglycemic conditions. Morphological changes that occur can include hippocampal brain atrophy, inflammation of nerves, changes in neurotransmitters, blood brain barrier injuries, energy metabolism disorders, and neuronal apoptosis. Increased apoptosis of these neurons occurs in the CA1 and CA3 layers of the pyramidal zone. Apoptosis of hippocampal neurons occurs through increased oxidative stress, deficits in mitochondrial function, impaired gene expression and inhibition of caspases. Antioxidants are compounds that can capture and reduce oxidative stress. Bay leaf is an antidiabetic plant that has high antioxidant properties, namely flavonoids and tannins. Flavonoids are antidiabetic compounds that reduce blood sugar levels which act as inhibitors of  glucosidase, maltase and  amylase enzymes. Flavonoids are also able to stimulate glucose uptake through GLUT-4 regulation. In addition to flavonoids, tannins are also antioxidants found in bay leaves and function as protectors of pancreatic beta cells from apoptosis due to oxidative stress. In addition, tannins can also increase levels of neurotropic factors and neuroastrocytes, injured brain, and modulate potential brain function so that can prevent neuronal apoptosis which is the main pathogenesis of diabetes.
Kajian Penerapan Material Ekspos pada Rumah Tinggal Ditinjau dari Segi Estetika Achsien Hidajat; Putri Hardiyanti; Ayu Anggraini; Dewi Yuliana
REKA KARSA Vol 1, No 2
Publisher : Institut Teknologi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26760/rekakarsa.v1i2.288

Abstract

Abstrak Rumah tinggal merupakan bangunan yang dijadikan tempat tinggal selama jangkawaktu tertentu, biasanya disesuaikan dengan suatu konsep tertentu agar mendapatkan kesan berbeda pada hasil yang ditampilkannya. salah satu konsep yang dapat diterapkan adalah konsep material ekspos. material ekspos merupakan desain pada bangunan yang dipandang sebagai bagian dari pekerjaan bangunan yang belum selesai atau tanpa proses finishing. kajian ini bertujuan untuk memahami penerapan konsep ekspos pada rumah tinggal agar memiliki nilai estetika yang baik. rumah tinggal setraduta k8/8 dipilih sebagai bahan studi kasus karena mengaplikasikan banyak variasi material pada konsep eksposnya. kajian material dibatasi pada material yang terdapat pada studi kasus saja karena material tersebut umum digunakan sebagai material ekspos. kajian estetika pun dibatasi dari segi warna dan tekstur saja karena merupakan pembeda antara bangunan ekspos dengan bangunan biasa. kajian ini diharapkan dapat menjadi bahan rujukan untuk mendesain bangunan rumah tinggal dengan konsep material ekspos agar memiliki nilai estetika yang baik. metoda penelitian yang digunakan adalah metoda analisis kualitatif yang terdiri dari proses pengamatan, pengumpulan data, penyaringan data, dan pengembangan teori tentang konsep material ekspos, jenis material ekspos, dan estetika. Kata Kunci: material ekspos, estetika tekstur dan warna, rumah tinggal. Abstract Residential building used as a residence for a certain period, usually tailored to a particular concept in order to get a different impression of the results of the display. One of the concepts that can be applied is the concept of material exposed. Exposed material is the design of the building is seen as part of an unfinished building work or without a finishing process. This study aims to understand the application of the concept of exposure in residences that have good aesthetic value. Setraduta residential k8 / 8 is selected as a case study for applying the many variations on the exposed material concept. The study material is limited to the material contained in the case studies just because the material is commonly used as a exposed material. Aesthetic study is limited in terms of color and texture only because it is the difference between building exposure to regular building. This study is expected to be a reference material for designing residential buildings with exposed material concepts that have good aesthetic value. The method used in this study is a qualitative analysis method which consists of a process of observation, data collection, data filtering, and material development of the theory of the concept of exposure, type of material exposure, and aesthetics. Keywords: exposed material, colors and textures aesthetic, residential building.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS KOMPUTER BERBANTUAN WORKSHEET UNTUK MATERI TURUNAN FUNGSI ALJABAR DI SMA/MA Ayu Anggraini; Armis Armis; Titi Solfitri
Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Vol 5: Edisi 1 Januari-Juni 2018
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan

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Abstract

Abstract : This research aims to develop computer-based learning media assisted by worksheet for derivative of algebra function. Development model using 4D model by Thiagarajan,et al there are (1) Define; (2) Design; (3) Develop; and (4) Disseminate. This research is limited to develop stage. On define stage, researcher make need analysis, on design stage make the paper based design, and on develop stage, media made by using Microsoft Office Power Point, then validated by four validators and revised based on validator's suggestion. Media was tested at two steps in class XI SMAN 8 Pekanbaru, there are small group test with six students and large group test with class XI MIA 10. Based on the results of data analysis obtained the result validation of media is 3,65 means very valid with the details are 3,56 for material aspect, 3,83 for learning aspect, 3,68 for program aspect, and 3,62 for display aspect, whereas for worksheet is 3,66 means very valid. Based on students questionnaire obtained the percentage of practicallity is 95,83% means very practice in small group test with the details 100% for material aspect, 97,2% for learning aspect, 91,67% for program aspect, and 91,67% language aspect. On the large group test obtained 94,25% means very practice with details are 92% for material aspect, 95,3% for learning aspect, 92% for program aspect, and 100% for language aspect. It can be concluded that computer-based learning media assisted by worksheet for derivative of algebra function are very valid and very practice for every aspects.Key Words: Computer-Based Learning, Research and Development, Derivative of Algebra Function.
PENATALAKSANAAN HOLISTIK PADA LANSIA USIA 68 TAHUN DENGAN TUBERKULOSIS PARU DENGAN PRINSIP PENDEKATAN KEDOKTERAN KELUARGA DI WILAYAH KERJA PUSKESMAS RAWAT INAP WAY KANDIS Ayu Anggraini
Jurnal Medika Hutama Vol. 5 No. 01 Oktober (2023): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Background: Tuberculosis is a type of infectious disease which is still a health problem in developing countries, including Indonesia. WHO states that in 2019 tuberculosis cases are expected to reach 10 million cases with 44℅ cases in the Southeast Asia region. In Indonesia, in 2020 the number of tuberculosis cases found was 543,874 cases, this figure slightly decreased when compared to 2019 where there were 566,623 cases found. Meanwhile, the number of Tuberculosis cases in Lampung Province in 2020 reached 16,006 cases with a case discovery rate of 54.6%. Objective: Application of holistic management with family doctor service approach by identifying risk factors, clinical problems, management and prevention of disease in patients based on a problem-solving framework with patient-centered, community-oriented and family-oriented approach. Method: This study is a case report analysis. Primary data is taken from autoanamnesis and alloanamnesis, physical examination, and visits to the patient's home. Secondary data was taken from patient medical records. Results: Based on holistic diagnosis. The patient is diagnosed with pulmonary tuberculosis and has internal risk factors in the form of a lack of knowledge about tuberculosis transmission and behavior to prevent transmission. Visits were made 3 times. Evaluation results show clinical improvement, and changes in patient and family behavior. Conclusion: Holistic management with the principles of family medicine is effective in providing clinical improvement and changes in patient and family behavior.
Efektivitas Fatwa Majelis Ulama Indonesia (MUI) ke-III Tentang Rokok ayu anggraini; Muhyidin
JOSH: Journal of Sharia Vol. 3 No. 02 (2024): Vol.03 No. 02 (Juni) 2024
Publisher : Institut Pesantren Sunan Drajat Lamongan, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55352/josh.v3i02.918

Abstract

One of the results produced by Ijtima’ Ulama of the Indonesian Fatwa Commission III which was held by the MUI (Indonesian Ulema Council) in 2009 in Padang Pajang was a fatwa concerning smoking. In the fatwa issued by the MUI, there are three points in the legal provisions regarding the cigarette law, namely first they agreed that there would be a difference regarding the smoking law, namely between makruh and haram. Secondly, the ijtima participants agreed to give the mandate to the Central MUI to establish a fatwa for the makruh or haram of smoking. Third, the ijtima’ulama agreed that smoking law is illegal for four things, namely smoking in public places, for children, for pregnant women and for the members of the Indonesian Ulama Council. This article seeks to examine the MUI fatwa in terms of its methodology.
Hubungan Pengetahuan Kader Tentang KPSP Stimulasi Deteksi Intervensi Dini Tumbuh Kembang (SDIDTK) Dengan Pelaksanaan SDIDTK Di Posyandu Wilayah Kerja Puskesmas Pasikolaga Kabupaten Muna Tahun 2024 SItti Alni Akmar; Ayu Anggraini
Jurnal Penelitian Sains dan Kesehatan Avicenna Vol 4 No 1 (2025): Jurnal Penelitian Sains dan Kesehatan Avicenna
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat (LPPM), Institut Teknologi Dan Kesehatan (ITK) Avicenna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69677/avicenna.v4i1.134

Abstract

Latar Belakang: Keberhasilan kader dalam SDIDTK sangat bergantung pada pengetahuan mereka. Pengetahuan yang baik pada kader meningkatkan status kesehatan masyarakat dan mendukung pencapaian posyandu mandiri. Kader yang berpengetahuan baik dapat memperbaiki keterampilan, membantu petugas, dan memperkuat kerja sama. SDIDTK penting untuk deteksi dini penyimpangan dalam pertumbuhan, perkembangan, dan kesehatan mental emosional anak. Proses ini harus dilakukan secara rutin dua kali setahun di posyandu untuk balita dan di sekolah untuk anak prasekolah, bukan hanya untuk anak yang dicurigai bermasalah. Tujuan: untuk mengetahui dan menganalisis hubungan antara pengetahuan kader tentang KPSP SDIDTK dengan pelaksanaan SDIDTK di posyandu wilayah kerja Puskesmas Pasikolaga. Metode: pendekatan analitik yang desainnya dengan cross sectional, sampel yang berjumlah 33 kader posyandu, dengan penarikan total sampel. SPSS digunakan untuk pengolahan data dan uji yang digunakan adalah uji chi-square dengan nilai kepercayaan kurang dari 0,05. Hasil: penelitian ini menunjukkan uji statistik didapatkan nilai p= 0,009 (α<0.05) sehingga dapat disimpulkan bahwa ada hubungan pengetahuan kader tentang KPSP SDIDTK dengan pelaksanan SDIDTK di posyandu wilayah kerja Puskesmas Pasikolaga. Hasil penelitian ini menunjukkan uji statistik didapatkan nilai p= 0,008 (α<0.05) sehingga dapat disimpulkan bahwa ada hubungan sikap kader tentang KPSP SDIDTK dengan pelaksanan SDIDTK di posyandu wilayah kerja Puskesmas Pasikolaga. Kesimpulan: dari penelitian ini bahwa ada hubungan sikap kader tentang KPSP SDIDTK dengan pelaksanan SDIDTK di posyandu wilayah kerja Puskesmas Pasikolaga
Pengaruh Promo Flash Sale 3.3 4.4 Pada Aplikasi Shopee Terhadap Minat Pembelian Mahasiswa Aktif Prodi Perbankan Syariah STEBIS IGM Palembang Ayu Anggraini; Havis Aravik; Meriyati, Meriyati
Jurnal Bisnis dan Manajemen (JURBISMAN) Vol. 1 No. 3 (2023): Jurnal Bisnis dan Manajemen (JURBISMAN)
Publisher : Penerbit dan Percetakan CV. Picmotiv

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61930/jurbisman.v1i3.236

Abstract

Penelitian ini membahas mengenai Pengaruh Promo Flash Sale 3.3 4.4 Pada Aplikasi Shopee Terhadap Minat Pembelian Mahasiswa Aktif Prodi Perbankan Syariah STEBIS IGM Palembag. Rumusan masalah pada penelitian ini adalah bagaimana Pengaruh Promo Shopee Flash Sale Pada Aplikasi Shopee Terhadap Minat Pembelian Mahasiswa Aktif Prodi Perbankan Syariah STEBIS IGM. Tujuan penelitian ini untuk menganalisis Pengaruh Promo Flash Sale 3.3 4.4 Pada Aplikasi Shopee Terhadap Minat Pembelian Mahasiswa Aktif Prodi Perbankan Syariah STEBIS IGM Palembang. Pada Penelitian ini menggunakan jenis penelitian kuantitatif yaitu metode analisis yang berdasarkan perhitungan yang dilakukan oleh peneliti. Data dalam penelitian ini menggunakan data sekunder yang diperoleh langsung dari responden yaitu mahasiswa aktif prodi perbankan syariah STEBIS IGM Palembang dengan menjawab kuisoner. Metode yang digunakan untuk menguji penelitian ini menggunakan uji regresi linear sederhana, uji parsial (t) dan uji determinasi (R²) yang di bantu program komputer SPSS ( Statistical Package For Social Science) versi 25. Hasil penelitian ini bahwa ada pengaruh yang positif dan signifikan pada Promo Flash Sale 3.3 4.4 Shopee Terhadap Minat Pembelian Mahasiswa Aktif Prodi Perbankan Syariah STEBIS IGM Palembang.
Efektivitas Fatwa Majelis Ulama Indonesia (MUI) ke-III Tentang Rokok ayu anggraini; Muhyidin
JOSH: Journal of Sharia Vol. 3 No. 02 (2024): Vol.03 No. 02 (Juni) 2024
Publisher : Universitas Sunan Drajat Lamongan, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55352/josh.v3i02.918

Abstract

One of the results produced by Ijtima’ Ulama of the Indonesian Fatwa Commission III which was held by the MUI (Indonesian Ulema Council) in 2009 in Padang Pajang was a fatwa concerning smoking. In the fatwa issued by the MUI, there are three points in the legal provisions regarding the cigarette law, namely first they agreed that there would be a difference regarding the smoking law, namely between makruh and haram. Secondly, the ijtima participants agreed to give the mandate to the Central MUI to establish a fatwa for the makruh or haram of smoking. Third, the ijtima’ulama agreed that smoking law is illegal for four things, namely smoking in public places, for children, for pregnant women and for the members of the Indonesian Ulama Council. This article seeks to examine the MUI fatwa in terms of its methodology.
COMPETITIVE ADVANTAGE IMPROVEMENT MODEL OF PT. BANK PEMBANGUNAN DERAH JAMBI THROUGH DIGITAL LEADERSHIP AND ORGANIZATIONAL CULTURE MEDIATED BY INNOVATIVE WORK BEHAVIOR Ayu Anggraini; Fitriaty; Lubis, Tona Aurora
Journal of Business Studies and Management Review Vol. 8 No. 2 (2025): JBSMR, Vol 8 No.2 June 2025
Publisher : Management Department, Faculty of Economics and Business, Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jbsmr.v8i2.41922

Abstract

This research aims toanalyzing the influence of digital leadership and organizational culture on the competitive advantage of Bank Jambi, through innovative work behavior. The research sample used was 242 respondents, taken using a simple random sampling technique. The types of data collected include primary data in the form of questionnaires on digital leadership, organizational culture, innovative work behavior, and competitive advantage, as well as secondary data in the form of other publications such as; books, journals and other documents related to the topic of this research. The data that has been collected is then analyzed using descriptive statistical analysis methods and verification analysis in the form of Partial Least Square (PLS). The results of the direct effect analysis prove that; (1) digital leadership and organizational culture directly have a significant effect on innovative work behavior, (2) digital leadership, organizational culture, and innovative work behavior directly have a significant effect on competitive advantage, (3) digital leadership indirectly has a significant effect on competitive advantage, through innovative work behavior, and (4) organizational culture indirectly has a significant effect on competitive advantage, through innovative work behavior. The results of this study have implications for efforts to improve innovative work behavior and competitive advantage of Bank Jambi, through a more adaptive corporate culture, as well as improving the quality of digital leadership, especially in terms of change management competency
Hubungan Berat Badan Lahir dan Panjang Badan Lahir Terhadap Kejadian Stunting Pada Balita Usia 24-59 Bulan Di Wilayah Kerja Puskesmas Nanggulan Kulon Progo Ayu Anggraini; Luluk Rosida; Esitra Herfanda
Bunda Edu-Midwifery Journal (BEMJ) Vol. 8 No. 2 (2025): September 2025
Publisher : Akademi Kebidanan Bunga Husada Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54100/bemj.v8i2.500

Abstract

Latar belakang : Stunting adalah keadaan di mana ukuran atau tinggi anak-anak tidak selaras dengan norma umurnya. Hal ini mencerminkan adanya gangguan dalam pertumbuhan fisik anak (Pertiwi et al., 2025). Salah satu faktor risiko terjadinya stuntingadalah berat badan lahir rendah, yaitu berat bayi ≤ 2.500 gram saat lahir, serta panjang badan lahir, yaitu panjang bayi ≤ 47 cm. Tujuan : Penelitian ini bertujuan untuk mengetahui Hubungan Berat Badan Lahir dan Panjang Badan Lahir terhadap kejadian Stunting pada balita usia 24-59 bulan di wilayah kerja Puskesmas Nanggulan Kulon Progo. Metode : Penelitian ini menggunakan desain kuantitatif dengan pendekatan case control, melibatkan populasi 887 balita. Sampel terdiri dari 45 kasus dan 45 kontrol, Teknik pengambilan sampel menggunakan teknik purposive sampling. Data dikumpulkan melalui buku KIA/KMS dan Rekam medis. Hasil : Dari 90 sampel, 45 Balita (50%) mengalami stunting, sedangkan 45 (50%) tidak stunting. Jumlah balita berat badan lahir 17 (18,9%) dan panjang badan lahir 34 (37,8%). Analisis statistik menggunakan Chi-square menunjukkan p-value 0.000, yang menunjukan adanya hubungan signifikan antara berat badan lahir, panjang badan lahir, dan kejadian stunting. Kesimpulan : Terdapat hubungan berat badan lahir dan panjang badan lahir dengan kejadian stunting di Puskesmas Nanggulan Kulon Progo.