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All Journal Jurnal EduHealth Action Research Literate (ARL)
Dwi Rantisari Thayeb, Andi Meinar
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Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Public Health Social Sciences Veterinary

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Evaluation Of Side Effects Of First-Line Antiretroviral (ARV) Therapy In HIV Patients At Kassi-Kassi Public Health Center Of Makassar Dwi Rantisari Thayeb, Andi Meinar; Kesrianti, A. Maya; Saputri, Rizky; Saleh, Adriandy
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

The treatment for HIV/AIDS therapy is by administering antiretrovirals (ARVs) for life, therefore it is necessary to monitor patients for side effects or symptoms of ARV toxicity. The aim of this study is to evaluate the side effects of drugs in HIV sufferers who were taking first-line antiretroviral (ARV) drugs at the Kassi-Kassi Public Health Centre of Makassar. This research was quantitative research with descriptive research type. The results showed that of the 36 patients who met the inclusion and exclusion criteria based on their characteristics, the majority of respondents were male (91.67%), in the 25-54 year age group (72.22%), and had a tertiary level education ( 58.33%). Based on the length of time they received antiretroviral drug therapy (ARV), the majority of patients were in the 6 months-5 years category (80.56%), with the most widely used ARV combination being tenofovir + lamivudine + efavirenz (47.22%). The number of patients who did not experience ARV side effects was greater (50.7%) than those who experienced side effects. The most common side effects include:dizziness, nausea, rash, fatigue and sleep disturbances. Even though several patients experienced ARV side effects, judging from the medical records, after treatment of ARV side effects, the patients continued therapy well.
Formulasi dan Uji Antioksidan Sediaan Serum Wajah dari Ekstrak Etanol Daun Binahong Merah (anredera cordifolia (tan.) Steenis) dengan Menggunakan Metode DPPH Marzuki, Asnah; Dwi Rantisari Thayeb, Andi Meinar; Luturdas, Kasparina
Action Research Literate Vol. 8 No. 8 (2024): Action Research Literate
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/arl.v8i8.479

Abstract

Daun Binahong Merah  (Anredera Cordifolia (Tan.) Steenis) memiliki kandungan metabolit sekunder yang berpotensi sebagai antioksidan yaitu flavonoid, saponin, tanin, vitamin C, alkaloid. Penelitian ini bertujuan untuk mengetahui  formulasi dalam bentuk sediaan serum ekstrak daun binahong merah (Anredera Cordifolia (Tan.)(Steenis) yang stabil secara fisik kimia dan dapat berpotensi sebagai aktivitas antioksidan berdasarkan nilai IC50. Metode penelitian ini secara eksperimental menggunakan metode maserasi dengan variasi konsentrasi yaitu F1 (5%); F2 (10%); F3 (15%); dalam pengujian aktivitas antioksidan menggunakan metode DPPH. Hasil evaluasi sediaan serum wajah menyatakan bahwa uji organoleptik diperoleh bentuk cairan sedikit kental, bau khas ekstrak, uji homogenitas diperoleh sediaan yang homogen, uji pH <0.14 , uji viskositas  <235, uji daya sebar <038, dan uji iritasi tidak menimbulkan iritasi pada kulit. Uji aktivitas antioksidan menunjukkan bahwa F1 (27,025). F2 (26,846). F3 (24,624). Maka disimpulkan bahwa serum dari ekstrak etanol daun binahong merah (Anredera Cordifolia (Tan.)(Steenis) memiliki kestabilan fisik dan kimia dan berpotensi sangat kuat sebagai antioksidan.
Formulation and Test of Antibacterial Activity Gel Mask Peel Off Stem and Suruhan Leaves (Peperomia Pellucida L.) Extract Against Propionibacterium Acne Farid, Nurfiddin; Dwi Rantisari Thayeb, Andi Meinar; Sulfiani, Sulfiani; Saleh, Adriandy
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

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Abstract

Stems and leaves of suruhan (Peperomia Pellucida L.) contain compounds belonging to the class of flavonoids, alkaloids, tannins, phenols, terpenes and essential oils which have potential as antibacterials. This study aimed to find out whether the stem and leaf extracts of suruhan (Peperomia pellucida L.) can be formulated into a gel peel-off mask preparation that is physically and chemically stable, and can inhibit the acne-causing bacteria Propionibacterium acne. This study used a laboratory experimental method, namely the formulation of Peel off gel mask preparations of stem and leaf extracts with different base concentration variations. Testing the characteristics of the preparation which includes organoleptic test, homogeneity, spreadability test, pH test, drying time test, viscosity test using the cycling test method and for antibacterial activity test using the well diffusion method. The results showed that the gel peel-off mask preparation of suruhan stem and leaf extract (Peperomia pellucida L.) fulfilled the requirements for the characteristics of the preparation both physically and chemically, and could inhibit the growth of acne-causing bacteria (Propionibacterium acne) at a concentration of 2% (15.1 mm), 3%, (17.8 mm) and 4% (19.4 mm) in the zone of strong inhibition. It can be concluded that formulation gel mask preparations Peel off stems and leaves of suruhan (Peperomia pellucida L.) can provide antibacterial activity against Propionibacterium acne with respective inhibition zones of 15.1 mm, 17.8 mm and 19.4 mm which are equally strong in inhibiting Propionibacterium acne bacteria
Co-Authors Asnah Marzuki Farid, Nurfiddin Kesrianti, A. Maya Luturdas, Kasparina Rizky Saputri, Rizky Saleh, Adriandy Sulfiani, Sulfiani