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All Journal Majalah Obstetri dan Ginekologi Jurnal Layanan Masyarakat (Journal of Public Service)
Kusumastuti, Etty Hari
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Humanities Decision Sciences, Operations Research & Management Environmental Science Health Professions Medicine & Pharmacology Social Sciences Other

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EDUCATION ABOUT BREAST CANCER IN THE COMMUNITY AT NGLUYU HEALTH CENTER, NGANJUK Mastutik, Gondo; Fauziah, Dyah; Rahaju, Anny Setijo; Rahniayu, Alphania; Ridholia; Kurniasari, Nila; Kusumastuti, Etty Hari; Ilmiah, Khafidhotul
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 8 No. 3 (2024): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v8i3.2024.422-431

Abstract

Breast cancer is the most common cancer found in the world and this cancer is the second cause of death due to cancer after lung cancer in Indonesia. This high mortality rate can be prevented by carrying out early detection. However, this is still not done well, especially in communities living in remote areas with low to medium economic and educational levels. The aim is to convey knowledge about breast cancer and training in the self-examination of the breast. It was held on Tuesday, 12 September 2023 at the Ngluyu Community Health Center, Nganjuk, from 07.00 to 14.00 WIB and was attended by 111 people. Data on breast cancer risk factors was collected through questionnaires. There were 96 participants who filled out the questionnaire, aged between 22-63 years. Risk factors data showed that 3.13% did not have children, 15.63% breastfed children less than 6 months, 5.21% were exposed to X-rays more than once a year; 1.04% had breast tumors, and 4.17% had family members suffering from cancer. In addition, 89.58% were over 25 years old and 42.71% had doing self-examination of breast. There was an increase in public understanding at the Ngluyu Community Health Center from 77.70% to 84.12%, namely an increase of 6.42%. This can increase public understanding about breast cancer and procedures to self-examination of breast and contribute in early detection of breast cancer as well as reducing the incidence of breast cancer. The results of this counseling can be used as recommendations by health centers in the Nganjuk district area.
Collagen-1 and elastin expression in cervical tissue: A comparison across cervical elongation, pelvic organ prolapse, and combined conditions Widyasari, Anis; Hardianto, Gatut; Kusumastuti, Etty Hari; Kurniawati, Eighty Mardiyan
Majalah Obstetri & Ginekologi Vol. 32 No. 3 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I32024.189-195

Abstract

HIGHLIGHTS Pathogenesis of cervical elongation is still limited, including the histological and molecular differences between a cervical elongation and a normal cervix. The expression of collagen-1 level in the cervical elongation group was stronger compared to the cervical elongation with POP and control group.   ABSTRACT Objective: This study aimed to assess differences in the expression of collagen-1 and elastin in cervical tissues among patients with Cervical Elongation (CE), Pelvic Organ Prolapse (POP), a combination of CE with POP, and those without either condition. Materials and Methods: An analytical study with a cross-sectional design was conducted, using immunohistochemistry (IHC) to analyze cervical tissue samples preserved in paraffin blocks. Patient groups included those diagnosed with CE, POP, CE combined with POP, and a control group without CE or POP. All participants underwent surgery between January 2021 and April 2023. IHC was used to measure the expression levels of collagen-1 and elastin in each tissue sample. Observations were made under 400x magnification, focusing on five randomly selected visual-field areas in each sample to determine the area fraction. Two experienced pathologists conducted the analyses in a blinded manner to ensure objective evaluation. Results: Statistical analysis using the Kruskal-Wallis test revealed significant differences in the expression of collagen-1 across the four groups (CE, POP, CE with POP, and control). Patients with CE showed a higher expression of collagen-1 than those with CE and POP combined, as well as the control group. However, no significant differences in elastin expression were observed among the groups. Conclusion: Collagen-1 expression differs significantly across patients with CE, POP, and CE combined with POP, suggesting a distinct role in cervical tissue remodeling in these conditions. Conversely, elastin expression was consistent across all groups, indicating that it may not play a differentiating role in these pathologies. These findings highlight collagen-1’s potential involvement in the structural changes associated with CE and POP.
Co-Authors Alphania Rahniayu Anis Widyasari Anny Setijo Rahaju, Anny Setijo DYAH FAUZIAH, DYAH Eighty Mardiyan K, Eighty Gatut Hardianto, Gatut Gondo Mastutik Ilmiah, Khafidhotul Nila Kurniasari Ridholia