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Gender Differences in Sociademographic Characteristics and Risk Factors Among Condyloma Acuminata Patients in DR. Moewardi General Hospital Surakarta Adniana Nareswari; Prasetyadi Mawardi; Arie Kusumawardhani; Endra Yustin Ellistasari
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2020): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v14i2.2169

Condyloma acuminata (CA) known as anogenital wart is the most frequent sexually transmitted infection worldwide. This highly infectious disease is caused by the human papilloma virus, whose its high reccurence rates contribute to direct medical costs, productivity loss and increased psychosocial impact. Thus, the prevention of this viral disease is more important than focusing on its treatment. This cross sectional retrospective study assesed the gender differences in sociodemographic characteristics and sexual risk factors of CA patients. There were 94 newly diagnosed CA patients, 47 males (50%) and 47 females (50%) during the period of January 2013- December 2017. The demographic data were taken from medical record and the additional data about the risk factors were from the questionnaires. Chi-square test was performed to compare between genders and p < 0.05 was considered statistically significant. There was significant difference between genders on all sociodemographic characteristics (age, occupation, education, marrital status) and risk factors (HIV/AIDS infection, condom using, age at the first sexual intercourse, number of lifetime sexual partner, type of intercourse) among CA patients. Our study revealed that male CA patients were mostly single, employed and multipartner, while CA female patients were mostly married, housewives and singlepartners.

Kombinasi Krioterapi dan KOH 5% untuk Terapi Kondiloma Akuminata Raksasa dengan Infeksi HIV Rini Hastuti; Etty Farida Mustifah; Endra Yustin Ellistasari
Cermin Dunia Kedokteran Vol 45, No 7 (2018): Onkologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i7.645

Pendahuluan. Kondiloma akuminata raksasa (KAR) atau disebut juga tumor Buschke-Lowenstein adalah tumor akibat infeksi human papillomavirus (HPV) di daerah anorektal dan genitalia eksterna dengan diameter lebih dari 2,5 cm. Kasus. Seorang laki-laki homoseksual, 32 tahun dengan benjolan yang bertambah banyak dan membesar sejak 2 bulan. Pasien terinfeksi HIV sejak 2 tahun. Kombinasi krioterapi dan larutan KOH 5% memberikan perbaikan klinis. Diskusi. Terapi kombinasi dapat dijadikan pilihan terapi KAR disertai penyulit atau jika terapi tunggal tidak memberikan perbaikan klinis.Background. Giant condyloma acuminata also known as Buschke-Lowenstein tumor is a tumor caused by human papillomavirus (HPV) infection in anorectal area and external genitalia with diameter more than 2,5 cm. Case. A 32 year-old homosexual male, with multiplying and growing lumps since two months. Patient was diagnosed with HIV since 2 years. A combination therapy with cryotherapy and KOH 5% solution resulted in clinical improvement. Discussion. Combination therapy may be an option for giant condyloma acuminata if single therapy does not provide clinical improvement.

Pemeriksaan Serologi untuk Diagnosis Sifilis Ambar Aliwardani; Putti Fatiharani; Fiska Rosita; Endra Yustin Ellistasari
Cermin Dunia Kedokteran Vol 48, No 11 (2021): Kardio-SerebroVaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i11.1563

Sifilis merupakan infeksi kronis bakteri T. pallidum subspesies pallidum dengan manifestasi klinis dapat menyerupai penyakit kulit lain. Diagnosis sifilis dari anamnesis dan pemeriksaan fisik harus selalu didukung oleh temuan laboratorium. Pemeriksaan serologi untuk deteksi antibodi terdiri dari pemeriksaan non-treponema untuk skrining dan evaluasi pengobatan serta pemeriksaan treponema untuk konfirmasi diagnosis. Klinisi hendaknya memahami pemeriksaan serologi agar dapat memilih pemeriksaan yang tepat sesuai klinis dan menentukan terapi. Syphilis is a chronic infectious disease caused by the bacteria T. pallidum subspecies pallidum with clinical manifestations resembling other skin diseases. Diagnosis should always be supported by appropriate laboratory findings. Serological examination to detect antibodies consists of non-treponema examination for treatment screening and evaluation and treponema examination for diagnosis confirmation. Clinicians should be able to choose the appropriate examinations for diagnosis and therapy.

Diaper Dermatitis Rakhma Tri Irfanti; Ance Imelda Betaubun; Ferry Arrochman; Ahmad Fiqri; Ummi Rinandari; Reti Anggraeni; Endra Yustin Ellistasari
Cermin Dunia Kedokteran Vol 47, No 5 (2020): CME - Continuing Medical Education
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i5.362

Diaper dermatitis (juga dikenal sebagai ruam popok, nappy rash, atau dermatitis iritan karena popok) adalah istilah umum untuk meggambarkan inflamasi akut pada area terkena popok; kondisi ini umumnya terjadi pada bayi. Etiologi dermatitis popok adalah multifaktorial. Diagnosis dan penatalaksanaan tepat mendapatkan hasil optimal; diperlukan kerjasama antara orang tua, pengasuh, dan tenaga medis.Diaper dermatitis (also known as diaper rash, nappy rash, or irritant dermatitis due to diapers) is a general term used to describe acuteinflammation in an area affected by a diaper; this condition generally occurs in infants. The etiology of diaper dermatitis is multifactorial. Proper diagnosis and management get optimal results; collaboration between parents, caregivers, and medical personnel is needed.

Late latent syphilis with early syphilis titer in pregnancy: A case report Frieda Yanuar; Eka Devinta Novi Diana; Wibisono Nugraha; Ammarilis Murastami; Endra Yustin Ellistasari
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art14

Syphilis is a chronic and systemic sexually transmitted infection caused by Treponema pallidum. The prevalence of syphilis according to the World Health Organization (WHO) is around 12 million cases worldwide and in pregnant women around 1.8 million cases. Syphilis screening in pregnancy is important to break the chain of transmission of congenital syphilis. We reported Mrs. S, 33 years old, 18 weeks pregnant, came with history of itchy patches appeared 8 months ago along with her husband and abortion 1 year ago. The plantar pedis dextra et sinistra showed multiple hyperpigmented macules and no clinical founding in the vagina. Serological tests, reactive Venereal Disease Research Laboratory (VDRL) 1:32, Treponema pallidum hemagglutination (TPHA) >1:5120 and non-reactive human immunodeficiency virus (HIV), support the diagnosis of latent syphilis. Patients were injected with benzathine penicillin 2.4 million units 3 times (1 week apart). Serological test evaluated at months 1, 3 and 6. At month 6, there was a decrease in VDRL value 4 times the initial value, indicating successful therapy in laten syphilis and had received therapy according to the guidelines for late latent syphilis. Syphilis in pregnancy can cause congenital syphilis in the fetus, although latent syphilis has no symptoms. The patient's VDRL titer was reactive in early latent syphilis (>1:8), but based on history and duration of infection more than 1 year including late latent syphilis. Based on this case report, we found that the VDRL titer value did not always correspond to the duration of infection.

Familial Lamellar Ichthyosis in 6 Years Old and 2 Years Old Children: A Rare Case Report Endra Yustin Ellistasari; Suci Widhiati; Ervina Rosmarwati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.724

Background: Lamellar ichthyosis (LI) is a rare non-syndromic congenital ichthyosis and is autosomal recessive. LI patients are generally born with abnormalities of keratinization, then develop into lamellar scales and persist into adulthood. This study aimed to describe cases of lamellar ichthyosis and provide appropriate management to prevent worsening patient prognosis. Case presentation: A 6-year-old girl and her younger brother, 2-year-old have been complaining of scaly skin all over their bodies since birth. Both patients were born with a history of being covered by a collodion membrane. On physical examination, thick and wide lamellar scales were seen with an erythematous base and palmoplantar hyperkeratosis. Ectropion of the eyelids, eclabium in the mouth area, and microtia in the ears were seen. The results of the dermoscopy examination showed brownish quadrilateral structures with white scales forming a lamellar pattern. Laboratory examination showed vitamin D insufficiency. Both patients were referred to the Pediatric Polyclinic regarding insufficiency and developmental complaints. Patients received therapy in the form of moisturizers, artificial eye drops, topical urea as a keratolytic, and oral vitamin D 2,000 IU per day. There was a clinical improvement after 3 months of treatment. Conclusion: Lamellar ichthyosis is an autosomal recessive congenital ichthyosis with clinical manifestations limited to the skin. In a minority of cases, LI can be inherited in an autosomal dominant manner. Thorough management is necessary to prevent a poor prognosis in patients.

Familial Lamellar Ichthyosis in 6 Years Old and 2 Years Old Children: A Rare Case Report Endra Yustin Ellistasari; Suci Widhiati; Ervina Rosmarwati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.724

Background: Lamellar ichthyosis (LI) is a rare non-syndromic congenital ichthyosis and is autosomal recessive. LI patients are generally born with abnormalities of keratinization, then develop into lamellar scales and persist into adulthood. This study aimed to describe cases of lamellar ichthyosis and provide appropriate management to prevent worsening patient prognosis. Case presentation: A 6-year-old girl and her younger brother, 2-year-old have been complaining of scaly skin all over their bodies since birth. Both patients were born with a history of being covered by a collodion membrane. On physical examination, thick and wide lamellar scales were seen with an erythematous base and palmoplantar hyperkeratosis. Ectropion of the eyelids, eclabium in the mouth area, and microtia in the ears were seen. The results of the dermoscopy examination showed brownish quadrilateral structures with white scales forming a lamellar pattern. Laboratory examination showed vitamin D insufficiency. Both patients were referred to the Pediatric Polyclinic regarding insufficiency and developmental complaints. Patients received therapy in the form of moisturizers, artificial eye drops, topical urea as a keratolytic, and oral vitamin D 2,000 IU per day. There was a clinical improvement after 3 months of treatment. Conclusion: Lamellar ichthyosis is an autosomal recessive congenital ichthyosis with clinical manifestations limited to the skin. In a minority of cases, LI can be inherited in an autosomal dominant manner. Thorough management is necessary to prevent a poor prognosis in patients.

Pemeriksaan Serologi untuk Diagnosis Sifilis Ambar Aliwardani; Putti Fatiharani; Fiska Rosita; Endra Yustin Ellistasari
Cermin Dunia Kedokteran Vol 48 No 11 (2021): Penyakit Dalam - COVID-19
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i11.155

Sifilis merupakan infeksi kronis bakteri T. pallidum subspesies pallidum dengan manifestasi klinis dapat menyerupai penyakit kulit lain. Diagnosis sifilis dari anamnesis dan pemeriksaan fisik harus selalu didukung oleh temuan laboratorium. Pemeriksaan serologi untuk deteksi antibodi terdiri dari pemeriksaan non-treponema untuk skrining dan evaluasi pengobatan serta pemeriksaan treponema untuk konfirmasi diagnosis. Klinisi hendaknya memahami pemeriksaan serologi agar dapat memilih pemeriksaan yang tepat sesuai klinis dan menentukan terapi. Syphilis is a chronic infectious disease caused by the bacteria T. pallidum subspecies pallidum with clinical manifestations resembling other skin diseases. Diagnosis should always be supported by appropriate laboratory findings. Serological examination to detect antibodies consists of non-treponema examination for treatment screening and evaluation and treponema examination for diagnosis confirmation. Clinicians should be able to choose the appropriate examinations for diagnosis and therapy.

Kombinasi Krioterapi dan KOH 5% untuk Terapi Kondiloma Akuminata Raksasa dengan Infeksi HIV Rini Hastuti; Etty Farida Mustifah; Endra Yustin Ellistasari
Cermin Dunia Kedokteran Vol 45 No 7 (2018): Onkologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i7.753

Pendahuluan. Kondiloma akuminata raksasa (KAR) atau disebut juga tumor Buschke-Lowenstein adalah tumor akibat infeksi human papillomavirus (HPV) di daerah anorektal dan genitalia eksterna dengan diameter lebih dari 2,5 cm. Kasus. Seorang laki-laki homoseksual, 32 tahun dengan benjolan yang bertambah banyak dan makin membesar sejak 2 bulan. Pasien terinfeksi HIV sejak 2 tahun yang lalu. Kombinasi krioterapi dan larutan KOH 5% memberikan perbaikan klinis. Diskusi. Terapi kombinasi dapat dijadikan pilihan terapi KAR disertai penyulit atau jika terapi tunggal tidak memberikan perbaikan klinis. Background. Giant condyloma acuminata also known as Buschke-Lowenstein tumor is a tumor caused by human papillomavirus (HPV) infection in anorectal area and external genitalia with diameter more than 2.5 cm. Case. A 32 year old homosexual male had multiplying and growing lumps since two months. Patient was diagnosed HIV since 2 years ago. A combination therapy with cryotherapy and KOH 5% solution resulted in clinical improvement. Discussion. Combination therapy may be an option for giant condyloma acuminata with complications or if single therapy does not provide clinical improvement.

Pemeriksaan Serologi untuk Diagnosis Sifilis Ambar Aliwardani; Putti Fatiharani; Fiska Rosita; Endra Yustin Ellistasari
Cermin Dunia Kedokteran Vol 48 No 11 (2021): Penyakit Dalam - COVID-19
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i11.155

Sifilis merupakan infeksi kronis bakteri T. pallidum subspesies pallidum dengan manifestasi klinis dapat menyerupai penyakit kulit lain. Diagnosis sifilis dari anamnesis dan pemeriksaan fisik harus selalu didukung oleh temuan laboratorium. Pemeriksaan serologi untuk deteksi antibodi terdiri dari pemeriksaan non-treponema untuk skrining dan evaluasi pengobatan serta pemeriksaan treponema untuk konfirmasi diagnosis. Klinisi hendaknya memahami pemeriksaan serologi agar dapat memilih pemeriksaan yang tepat sesuai klinis dan menentukan terapi. Syphilis is a chronic infectious disease caused by the bacteria T. pallidum subspecies pallidum with clinical manifestations resembling other skin diseases. Diagnosis should always be supported by appropriate laboratory findings. Serological examination to detect antibodies consists of non-treponema examination for treatment screening and evaluation and treponema examination for diagnosis confirmation. Clinicians should be able to choose the appropriate examinations for diagnosis and therapy.

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