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Agustini, Dewi Darwati
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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PENGGUNAAN METFORMIN PADA PASIEN POLYCYSTIC OVARY SYNDROME (PCOS) Salasanti, Citra Dewi; Agustini, Dewi Darwati; Ramdani, Amalia Dewi
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1139

Abstract

Infertility in women of reproductive age with Polycystic Ovary Syndrome (PCOS) in Indonesia is increasing. Insulin resistance occurs in some PCOS patients, so the use of insulin sensitivity-enhancing drugs such as metformin is recommended. This study was conducted to determine the use of metformin in PCOS patients at independent doctor's practices in Bandung City. The study was conducted as an observational descriptive study with data collected retrospectively using purposive sampling. Data were taken from patient medical records and interviews with the doctor in charge. The sample in this study consisted of patients who met the inclusion and exclusion criteria. The data obtained were then summarized and displayed in table form. The results showed that the majority of PCOS patients were 26-30 years old with marriages that had lasted for 3 years. Ovulation and pregnancy in PCOS patients who used oral metformin treatment occurred in 15% of cases. The metformin used had a dose of 500-850 mg, which was given twice a day for 4-9 months.
The STUDI INTERAKSI OBAT ANTIHIPERLIPIDEMIA PADA PASIEN RAWAT JALAN DI SALAH SATU RUMAH SAKIT SWASTA CIKAMPEK Amal, Andi Nurzakiah; Agustini, Dewi Darwati; Amal, Surya
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1209

Abstract

Hyperlipidemia is a lipid metabolism disorder characterized by an increase in total cholesterol levels in the blood, which is a risk factor for various cardiovascular diseases. Treatment of hyperlipidemia is often combined with other drugs, increasing the potential for drug interactions. This study aims to identify the severity of antihyperlipidemia drug interactions in outpatients in private hospitals in Cikampek during the period of June to December 2023. The research uses an analytical survey design with a retrospective approach. Data were obtained from 251 patient prescriptions that met the inclusion criteria and were analyzed univariably using the Stockley Drug Interaction and drugs.com application. The results showed that 67.65% of prescriptions had potential drug interactions, while 32.35% did not. Patients aged 50–59 years were the largest group (42.6%) receiving antihyperlipidemia, with simvastatin being the most frequently prescribed drug and causing drug interactions most often (51.11%). Of the 135 cases of drug interactions identified, moderate severity accounted for 57.03%, while major severity reached 46.97%. No cases with minor severity were found. This study highlights the importance of monitoring drug interactions to prevent more serious risks in hyperlipidemia patients.
STUDI PELAPORAN KEJADIAN NYARIS CEDERA (KNC) DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT DI KARAWANG TAHUN 2017 Agustini, Dewi Darwati; Safitri, Maida; Mariam, Iyam
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1379

Abstract

Pelaporan keselamatan pasien pada pelayanan kefarmasian dititikberatkan pada KNC yang menjadi aspek penting dalam menunjang keselamatan pasiend engan mengurangi terjadinya medication error. Penelitian ini bertujuan untuk mengetahui banyaknya angka kejadian nyaris cedera yang dilaporkan selama tahun 2017 dan pada bagian mana paling sering terjadinya KNC di unit rawat jalan RSUD Karawang. Penelitian dilakukan bersifat deskriptif cross sectional. Penelitian dilakukan pada lembar rekapitulasi laporan KNC selama tahun 2017. Hasil penelitian menunjukkan selama tahun 2017 terjadinya KNC pada penginputan resep sebanyak 316 kali, penulisan etiket 47 kali, peracikan 122 kali, dan penyerahan obat sebanyak 4 kali. Total keseluruhan terjadi KNC sebanyak 489 kali atau sekitar 0,5% terhadap lembar resep. Dapat disimpulkan bahwa selama tahun 2017 bagian yang paling sering mengalami KNC adalah pada penginputan resep sebanyak 316 kali terjadinya KNC.
Co-Authors Amal, Andi Nurzakiah Amal, Surya Citra Dewi Salasanti Iyam Mariam Ramdani, Amalia Dewi Safitri, Maida